CHEMISTRY 208

ORGANIC AND BIOLOGICAL CHEMISTRY FOR THE HEALTH SCIENCES

SPRING 2011

Instructor: Duane Smith, Jr., Ph.D. Course section: CHEM 208-6M

Office: BEA 134 Room: BEA 165

Office Hours: MWF 7:30 – 9:30 am Meeting Time: MWF 12:55 – 1:50 pm

TR 9:00 – 12:00 noon

(or as arranged with the instructor)

Phone: (985) 448-4165 Email:

COURSE DESCRIPTION: CHEM 208. Organic and Biological Chemistry for the Health Sciences. 330. Prerequisite: CHEM 101. Emphasis is on practical aspects of biochemistry necessary for the comprehension of biological processes occurring within the human body. A course designed for students in various health related programs – nursing, dietetics, etc. Degree credit will not be given for both CHEM 208 and 435. This course is also available via Internet. Basic computer knowledge is required for students enrolled in the Internet section. (40.0599)

PRE-REQUISITE: CHEM 101

REQUIRED TEXT: Organic & Biochemistry by Janice Gorzynski Smith, McGraw Hill publisher, 2010 (ISBN 0077329694).

RECOMMENDED: A course website is set up at the Nicholls Blackboard™ server: http://www.nicholls.edu At this website, you will find a copy of this syllabus, the course calendar, a discussion forum, Internet resources, and online quizzes.

As a student attending Nicholls, you have access to several computer labs on campus (Cenac, WAC, LS&T) through a dial-in account, and at the Ellender library.

COURSE GOAL: The goal of this class is to help the student become familiar and comfortable with the concepts, terms, and processes of organic chemistry. Fundamental aspects of organic compounds and biological molecules and their reactivity will be explored. The student will be able to name and identify basic molecules, recognize reactions and write equations.

GENERAL EDUCATION STUDENT LEARNING OUTCOMES

CHEM 208 , as a Core Curriculum course, fulfills three hours of general education requirements in the area of the natural sciences and is thus designed to enable students to meet the following broad outcome for all the natural sciences:

Goal: Upon completion of the undergraduate curriculum, students will be able to comprehend and to apply the basic principles of science and methods of scientific inquiry.

For further explanation of the learning objectives associated with this goal, go to http://www.nicholls.edu/gened/goals_objectives.html.

STUDENT OUTCOME OBJECTIVES: Upon completion, the student will be able to:

1.  Identify and name organic and biological molecules

2.  Draw organic and biological molecules or deduce their structure from the name

3.  Understand the structural features of organic functional groups

4.  Discuss the metabolism of carbohydrates, lipids, and protein molecules

5.  Analyze the kinetic principles associated with the enzymatic process

6.  Classify and characterize carbohydrates and their importance in metabolism

7.  Identify amino acids and understand their importance in protein metabolism

8.  Understand and explain the chemical bonding concepts of organic molecules

9.  Understand the effects of chirality of molecules on metabolism

10.  Recognize and identify the various levels of protein structure and function

11.  Discuss the production and metabolism of ATP

COURSE CONTENT:

1.  Structure and classification of simple organic molecules

2.  Structure and classification of biologically-important organic macromolecules

a.  Carbohydrates

b.  Lipids

c.  Proteins

d.  Nucleic Acids

3.  Biochemical energy production

4.  Basic metabolic pathways in

a.  Glycolysis

b.  Citric Acid Cycle

c.  Oxidative Phosphorylation

d.  Lipid Metabolism

e.  Protein Metabolism

COURSE REQUIREMENTS:

1.  Required written work:

a.  Homework assignments (10%)

b.  Exams (90%)

2.  Activities

a.  Cooperative group discussions

b.  Quizzes

METHOD OF EVALUATION:

Grades will be based on a 10-point grading scale.

90 – 100 A

80 – 89 B

70 – 79 C

60 – 69 D

< 60 F

*Grades will be based on the average of four exams plus the Final with the option of dropping the lowest grade, excluding the final exam. Several topic area quizzes may be given throughout the semester, and the average quiz grade may account for 10% of the total grade. Homework assignments will be made throughout the semester and will account for 10% of the total grade value. This grading policy may be amended due to any unforeseen changes in schedule.

MAKE-UP POLICY: If a student misses a class, he or she is still responsible for the material covered during that class period. If a student misses an exam, a makeup will not be given unless the student notifies the instructor in advance of his or her absence. If no advance notice is given, the student must provide documentation as to the reason for having been absent, such as death of a close family friend (death notice), illness (doctor’s bill), or court appearance (summons).

ATTENDANCE POLICY: Absences amounting to the equivalent of 10% of class time, whether consecutive or not, is grounds for the student being dropped from the course. You are expected to be present, prepared, and alert at all sessions.

ACADEMIC HONESTY POLICY: Any student found cheating will be subject to the penalties as stated in the Student Code of Conduct Handbook; including, but not limited to, a score of zero on an exam, expulsion from the class, and/or expulsion from the University.

SEMESTER WITHDRAWALS:

The responsibility for withdrawing from the course, if you decide not to continue, lie completely with the student. Failure to drop a course by the final deadline will result in your receiving a grade of “F”. The last day to drop the course with a “W” is Monday, March 28, 2011.

DISABILITIES POLICY: If you have a documented disability that requires assistance, you will need to register with the Office of Disability Services for coordination of your academic accommodations. The Office of Disability Services is located in Peltier Hall, Room 100-A. The phone number is (985) 448-4430 (TDD 449-7002).

ACADEMIC GRIEVANCES: The proper procedure for filing a grade appeal or grievances related to other academic matters is listed in Section 5 of the Code of Student Conduct and at the following link: http://www.nicholls.edu/documents/student_life/code_of_conduct.pdf

CONTINUED LEARNING FOLLOWING AN EXTREME EMERGENCY: In order to make continued learning possible following an extreme emergency, students are responsible for:

·  reading regular emergency notification on the NSU website; http://www.nicholls.edu

·  knowing how to use and access Blackboard (or university designated electronic delivery system);

·  being familiar with emergency guidelines;

·  evacuating with textbooks and other course materials;

·  knowing their Blackboard (or designated system) student login and password;

·  contacting faculty regarding their intentions for completing the course.

Faculty are responsible for:

·  their development in the use of the Blackboard (or designated) software;

·  having a plan for continuing their courses using only Blackboard and email;

·  continuing their course in whatever way suits the completion of the course best, and being creative in the continuation of these courses;

·  making adjustments or compensations to a student’s progress in special programs with labs, clinical sequences or the like, only in the immediate semester following the emergency.

NO AUDIBLE BEEPERS OR TELEPHONES WILL BE ALLOWED IN CLASS. Be sure that these devices are turned off or on silent mode as you enter the classroom. These devices are a distraction to the instructor as well as your classmates. If there is an emergency and you need to respond please let the instructor know of this before the class starts.

THIS SYLLABUS, IN NO WAY, IS TO BE MISCONSTRUED AS A CONTRACT, AND MAY BE AMENDED BY THE INSTRUCTOR AS DEEMED NECESSARY.

OUTLINE OF TOPICS

CHAPTER(S) POINTS

11. Introduction to Organic Molecules

12. Alkanes (Saturated Hydrocarbons)

13.  Unsaturated Hydrocarbons

14.  Organic Compounds that Contain Oxygen, Halogens, or Sulfur

EXAM 1 (Fri., Feb. 11) 100

15. The Three-Dimensional Shape of Molecules

16.  Aldehydes and Ketones

17.  Carboxylic Acids, Esters, and Amides

18.  Amines and Neurotransmitters

EXAM 2 (Fri., Mar. 4) 100

19.  Lipids

20. Carbohydrates

21. Amino Acids, Proteins, and Enzymes

LAST DAY TO DROP WITH ‘W’ GRADE IS Monday, March 28, 2011

EXAM 3 (Fri., Apr. 1) 100

22.  Nucleic Acids and Protein Synthesis

23.  Digestion and the Conversion of Food into Energy

24.  Carbohydrate, Lipid, and Protein Metabolism

EXAM 4 (Weds., May 4) 100

FINAL EXAM (Fri., May 6 at 1:00 p.m.) 100

TOTAL POINTS 500*

*Note: Able to drop lowest exam score excluding Final Exam. Everyone MUST take the Final Exam. Average exam score will constitute 90% of the final grade. Homework constitutes 10% of the final grade.