Web Table 1. TCR and TCRgene rearrangements in thymocytes of c-Myc–/–
RAG-1–/– chimeras
Genotype / V / N / D / N / J / TCR joinsC57BL/6 / TTC TGT GCC AGC TC / C C / GA CTG GGG / TTA / CAA GAC ACC CAG TAC TTT GGG / V5J2.5
TTC TGT GCC AGC TCT CTC / TTA / GGA CT / T / CAA GAC ACC CAG TAC TTT GGG
TTC TGT GCC AGC TCT C / C / G ACA G / AG G / AA GAC ACC CAG TAC TTT GGG
TTC TGT GCC AGC TCT C / CT C / GG ACT GGG GG / T CG / A GAC ACC CAG TAC TTT GGG
c-Myc–/–RAG-1–/– / TTC TGT GCC AGC TCT C / G / G GGA CAG / A / AA GAC ACC CAG TAC TTT GGG
TTC TGT GCC AGC TCT C / CC / GGG ACA / CA / CAA GAC ACC CAG TAC TTT GGG / *
TTC TGT GCC AGC TCT C / AC / GGG ACT GGG GGG / CT / A GAC ACC CAG TAC TTT GGG / *
TTC TGT GCC AGC TCT CT / A GA / G GGG GGG C / T / C CAA GAC ACC CAG TAC TTT GGG
C57BL/6 / TTC TGT GCC AGC GGT G / G / G GGA CAG / TAA / T TCC TAT AAT TCG CCC CTC TAC TTT GCG / V8J1.6
TTC TGT GCC AGC GGT GA / G ACA / ACA CT / C TAT AAT TCG CCC CTC TAC TTT GCG
TTC TGT GCC AGC GGT G / GC / GAC AGG GG / T / TAT AAT TCG CCC CTC TAC TTT GCG
TTC TGT GCC AGC GGT GAT / TGG GGG G / TT / TCC TAT AAT TCG CCC CTC TAC TTT GCG
c-Myc–/–RAG-1–/– / TTC TGT GCC AGC GGT GA / C AGG GG / T AAT TCG CCC CTC TAC TTT GCG / *
TTC TGT GCC AGC GGT GAT G / CA C / GA / T TCC TAT AAT TCG CCC CTC TAC TTT GCG / *
C57BL/6 / TTC TGT GCC AGC GGT GA / A T / CA / A / CA AAC ACC GGG CAG CTC TAC TTT GGT / V8J2.2
TTC TGT GCC AGC GGT GA / C CA / C AGG G / AC ACC GGG CAG CTC TAC TTT GGT
TTC TGT GCC AGC GGT GAT G / CA CG / A GG / A GG / C ACC GGG CAG CTC TAC TTT GGT
TTC TGT GCC AGC GGT GAT G / CT GG / C ACC GGG CAG CTC TAC TTT GGT
c-Myc–/–RAG-1–/– / TTC TGT GCC AGC GGT GAT G / TG GGG GGG / AAC ACC GGG CAG CTC TAC TTT GGT / *
TTC TGT GCC AGC GGT GAT / CA / G GGG GGG / AAC ACC GGG CAG CTC TAC TTT GGT / *
TTC TGT GCC AGC GGT GAT G / GG GTG / AAC ACC GGG CAG CTC TAC TTT GGT
TTC TGT GCC AGC GGT GAT G / CA CAA / ACT G / CA AAC ACC GGG CAG CTC TAC TTT GGT
C57BL/6 / TAT TAC TGT GCC TCG GGC / GGA / CTC G / CT ACC GAC AAA CTC GTC / V5J1
TAT TAC TGT GCC TCG GGG TAT / ACG / CC GAC AAA CTC GTC
TAT TAC TGT GCC TCG GGG / C / GA GGG ATA CG / G GCT A / ACC GAC AAA CTC GTC
c-Myc–/–RAG-1–/– / TAT TAC TGT GCC TCG G / AA ATA TGC / GAG GGA TAC GAG / CTT AGG / ACC GAC AAA CTC GTC
TAT TAC TGT GCC TCG GGG TAT / GA / C GGA GGG ATA CGA G / CT GT / C GAC AAA CTC GTC / *
TAT TAC TGT GCC TCG GG / C AGT / GGG ATA / TCG GAG / CT ACC GAC AAA CTC GTC
TAT TAC TGT GCC TCG GGG TAT / ATC GGA GGG ATA / CT ACC GAC AAA CTC GTC
Gene rearrangements are shown according to germline contributions from V, D and J segments and presumed template-independent N or P nucleotides. Asterisk (*) denotes sequence represented more than once.