Therapeutic Options in Drug Resistant Epilepsy
Bucharest, Novotel Hotel, 23-25th of April 2015
Organized by
Romanian Neurological Society (SNR)
in collaboration with
Romanian Society for Pediatric Neurology(SRNP)
Thursday 23 rd of April 2015 - Genetic epilepsies
Morning session
Chairs : Olivier Dulac andIoana Mindruta
09.00 – 09.10 Opening remarks
09.10 – 10.00Epileptic syndromes with genetic etiology
Olivier Dulac, Paris, France
10.00 – 10.20 Role of genetic mechanisms for therapeutic options
Catrinel Iliescu
10.30 - 11.00 Role of genetics in pharmacoresistance
Dana Craiu
11.00 -11.20 coffee break
Chairs: Petia Dimova and Dana Craiu
11.20 – 11.50 Epilepsies related to chromosomal disorders – clinical cases
Diana Barca, Magda Budisteanu, Catrinel Iliescu, Cristina Motoescu, Cristina Pomeran, Oana Tarta-Arsene, Madalina Leanca, Nina Butoianu, Carmen Burloiu, Dana Craiu
11.50 – 12.20 Treating epilepsy in adolescence
Dana Craiu
12.20 – 13.00 Clinical cases in adult population
Csilla Nagy, Ana Ciurea, Irina Popa, Raluca Gurgu
13.00 – 14.00 Lunch
Afternoon session
Chairs: Carmen Burloiu and Raluca Teleanu
14.00 – 14.30 How do we get to the diagnosis in genetic epilepsies?
Petia Dimova, Sofia, Bulgaria
14.30 – 15.00 Malformation of cortical development
Raluca Teleanu, Bucharest, Romania
15.00 – 15.30 Phenotype and genotype spectrum in Dravet Syndrome
Dana Craiu
15.30 – 16.00 ESES – clinical manifestations and genetics
Cristina Pomeran, Cristina Motoescu
16.00 – 16.20 Coffee break
Chairs: Catrinel Iliescu and Oana Tarta
16.20 – 17.20 The role of cerebellum and basal ganglia in epilepsy
Olivier Dulac, Paris, France
17.20 – 17.50 Photosensitivity and genetic determinism
Carmen Sandu, Catrinel Iliescu, Cristina Motoescu, Cristina Pomeran, Alice Dica, Dana Craiu
17.50 – 18.00Discussions, Q&A
Friday, 24th of April – Surgical treatment in MRI positive vs. MRI negative epilepsies
Morning session
Chairs: Philippe Kahane and Dana Craiu
09.00 – 09.50Presurgical evaluation and surgery results in symptomatic partial epilepsy (MRI positive)
Lorella Minotti, Grenoble, France
09.50 – 10.50 Clinical cases – pediatric epilepsy
Oana Tarta Arsene, Alice Dica, Cristina Pomeran, Cristina Motoescu, Carmen Sandu, Dana Craiu, Bucharest, Romania
10.50 – 11.00 Discussions, Q&A
11.00 – 11.20 coffee break
Chairs: Petia Dimovaand Raluca Teleanu
11.20 –12.10 Presurgical evaluation and surgical outcome in MRI negative epilepsies
Philippe Kahane, Grenoble, France
12.10 – 12.40 Romanian experience in the National Program for Pharmacoresistant Epilepsies
Ioana Mindruta, Bucharest. Romania
12.40 – 13.00 Case discussions (adult and pediatric patients)
Adina Roceanu, Catrinel Iliescu, Carmen Burloiu, Bucharest, Romania
13.00 – 14.00 lunch
Afternoon session
Chairs: Lorella Minotti and Catrinel Iliescu
14.00 – 14.20Lesions located in the eloquent cortex - presurgical evaluation and surgery outcome in lesional occipital lobe epilepsies in children
Laura Craciun, Bucharest, Romania
14.20 – 15.00 Epilepsy surgery in genetic epilepsies
Petia Dimova, Sofia, Bulgaria
15.00 – 15.15 Radiofrequency thermocoagulation, possible alternative to open brain surgery
Irina Popa, Ana Ciurea, Alin Rasina, Jean Ciurea, Bucharest, Romania
15.15 – 15.30 Case discussion
15.30 – 15.45 coffee break
Chairs: Carmen Burloiu and Ioana Mindruta
15.45 – 16.15 Case discussions in adult population
Irina Constantinescu (Iasi) and Sanda Petrutiu (Tg Mures)
16.15 – 17.45Case discussions in pediatric population
Raluca Teleanu, Bucharest, Romania
17.45 – 18.00 Discussions, Q&A
Saturday, 25th of April, 2015
1) Neurostimulation methods for brain mapping and therapy in drug resistant epilepsies
Chairs: Andrei Barborica and Jean Ciurea
09.00 – 09.40 Neurostimulation for brain mapping in presurgical evaluation
Lorella Minotti, Grenoble, France
09.40 – 10.20 Neurostimualtion as a therapeutic tool in drug resistant epilepsy VNS and DBS
Philippe Kahane, Grenoble, France
10.20 – 10.40 Vagal nerve stimulation - surgical technique
Mircea Gorgan, Felix Brehar, Bucharest, Romania
10.40 -11.00 coffee break
2) Signal analysis methods and the epileptogenic networks
Chairs: Olivier David and Adina Mincic
11.00 – 11.40 StereoEEG method and computer assisted signal analysis
Olivier David, Grenoble, Franta
11.40 – 12.10Modern methods to study cognition - applicability in epilepsy
Adina Mincic, Oradea, Romania,
12.10 – 12.40 Microelectrodes recordings in the seizure onset zone
Andrei Barborica, Bucharest, Romania
12.40 – 13.10 StereoEEG method – surgical technique for electrodes implantation
Bogdan Balanescu, Ana Ciurea, Alin Rasina, Jean Ciurea
13.10 – 13.40A functional connectome of the human brain based on intracranial electrical stimulation in patients with epilepsy
Cristian Donos, Romania
13.40 – 13.50Discussions
13.50 – 14.00Closing remarks