Table S9. Alignment of genomic region surrounding rs1990760 for available mammal genomes. The base corresponding to rs1990760 is nearly universally conserved as “G”, with a resulting alanine codon. Sequence is shown reverse complement, in the direction of the reading frame, showing five codons in either direction. Squirrel may have a threonine (Thr) side-chain; interestingly, tenrec may have a 2-amino acid deletion. Alignment of Chr2: 163124034 - 163124066, 33 bps (reverse complement).

Species / Scientific name / Version / 5’ sequence / codon / 3’ sequence
Human / Homo sapiens / hg19/GRCh37 / GTAAGAGAAAACAAA / GCA / CTGCAAAAGAAGTGT
Chimp / Pan troglodytes / panTro2 / GTAAGAGAAAACAAA / GCA / CTGCAAAAGAAGTGT
Gorilla / Gorilla gorillagorilla / gorGor1 / GTAAGAGAGAACAAA / GCA / CTGCAAAAGAAGTGT
Orangutan / Pongopygmaeusabelii / ponAbe2 / GTAAGAGAAAACAAA / GCA / CTGCAAAAGAAGTGT
Rhesus / Macacamulatta / rheMac2 / GTAAGAGAAAATAAA / GCC / CTGCAAAAGAAGTGT
Baboon / Papiohamadryas / papHam1 / GTAAGAGAAAACAAA / GCC / CTGCAAAAGAAGTGT
Gibbon / Nomascusleucogenys / NCBI trace archive / GTAAGAGAAAACAAA / GCA / CTGCAAAAGAAGTGT
Marmoset / Callithrixjacchus / calJac1 / GTGAGAGAAAACAAA / GCA / CTGCAAAAGAAGTTT
Tarsier / Tarsier syrichta / tarSyr1 / GTGAGAGAAAACAAA / GCA / TTGCAAAAAAAGTTT
Bushbaby / Otolemurgarnettii / otoGar1 / ATGAGAGAAAACAAA / GCT / CTGAAAGAGAAGTTT
Tree shrew / Tupaiabelangeri / tupBel1 / GTGAGAGAAAACAAA / GCA / CTACAAGAGAAGTTT
Mouse / Musmusculus / mm9 / GTAAGAGAAAACAAA / GCA / CTGCAAAAGAAATTT
Rat / Rattusnorvegicus / rn4 / GTGAGAGAGAACAAA / GCA / CTACAAATGAAATTT
Naked mole rat / Heterocephalusglaber / NCBI trace archive / GTGAGAGAAAACAAA / GCA / CTGCAAAATAAGTTT
Guinea pig / Caviaporcellus / cavPor3 / ACAAGAGAAAACAAA / GCA / CTGCAAAGTAAGTTC
Squirrel / Spermophilustridecemlineatus / speTri1 / GTGACAGAAAACAAA / ACT / CTGCAGAAGAAGTTT
Rabbit / Oryctolaguscuniculus / oryCun2 / GTGAGAGAAAGCAAA / GCA / CAAAAGAAGAACTTT
Alpaca / Vicugnapacos / vicPac1 / GTGAGAGGAAACAGA / GCA / CTGCAAAACAGGTTT
Dolphin / Tursiopstruncatus / turTru1 / GTGAGAGGAAACAAA / GCA / CTGCAAACAAAGTTT
Cow / Bostaurus / bosTau4 / GTGAGAGGAAACAAA / GCA / CTGCAAACAATGTGT
Pig / Susscrufa / NCBI trace archive / GTGAGAGGAAACAAG / GCA / CTGCAGACGAAGTTT
Horse / Equuscaballus / equCab2 / GTGAGAGAAAACAAA / GCA / CTGAAAAAGAAGTTT
Cat / Feliscatus / felCat3 / GTGAGAGAAAACAAA / GCC / CTACGAAAGAAGTTT
Dog / Canis lupus familiarus / canFam2 / GTGAGAGAAAACAAA / GCA / CTACGAAAGAAGTTT
Microbat / Myotislucifugus / myoLuc1 / GTGAGAGAAAACAAA / GCA / CTGCAAAAGAAGTTT
Megabat / Pteropusvampyrus / pteVam1 / ATGAGAGAAAACAAA / GCA / CTGAAAAAGAAGTTT
Hedgehog / Erinaceuseuropaeus / eriEur1 / GTGATAGAAAACAAA / GCA / CTGAAAAAGAAATTT
Shrew / Sorexaraneus / sorAra1 / GTCATAGAAAACAAA / GCA / CTAAAAGAAAAGTTT
Elephant / Loxodontaafricana / loxAfr3 / GTGAGAGAAAACAAA / GCA / TTGCAAAAAAAGTTT
Panda / Ailuropodamelanoleuca / NCBI / GTGAGAGAAAACAAA / GCA / CTACGGAAGAAATTT
Tenrec / Echinopstelfairi / echTel1 / GTGAGAGAAGGCACG / --- / ---AAAAGCAAGTTT
Armadillo / Dasypusnovemcinctus / dasNov2 / GTGAGAGAAAACAAA / GCA / TTGCAAGAGAAGTTT
Sloth / Choloepushoffmanni / choHof1 / GTGAGAGAAAACAAA / GCA / CTACAAGAGAAGTTT
Wallaby / Macropuseugenii / macEug1 / GTAAGAGAAAATAAA / GCA / TTGCAAAAGAAATTC
Opossum / Monodelphisdomestica / monDom5 / GTAAGAGAAAATAAA / GCA / CTACAAAAGAAATTT