CURRICULUM VITAE

06/12

NAME: Rodney D. Wiersma

ACADEMIC RANK:The University of Chicago, Assistant Professor, Full Time

DEPARTMENT:Radiation and Cellular Oncology

CITIZENSHIP:Canadian

TITLE:Assistant Professor of Clinical Radiation and Cellular Oncology

BUSINESS ADDRESS:

Department of Radiation and Cellular Oncology

University of ChicagoMedicalCenter

5758 South Maryland Avenue, MC 9006

Chicago, IL 60637

Voice: 773-702-6874

Fax: 773-834-7299

EDUCATION:

09/95–04/99University of Alberta, Canada, Bachelor of Science with Honors in Physics

09/99–06/02SimonFraserUniversity, Canada, Master of Science in Physics

06/02–05/06University of Hanover/Max-Plank-Institute, Germany, Doctor of Philosophyin Physics

Academic Appointments:

09/99–06/02Research Assistant, SimonFraserUniversity, Vancouver, Canada

06/02–05/06Research Assistant, Max-Plank-Institute FKF, Stuttgart, Germany

06/06–12/08Postdoctorial Scholar in Medical Physics, StanfordUniversity, Stanford, USA

12/08–present Assistant Professor, Dept. of Radiation and Cellular Oncology, Committee on Medical Physics, The University of Chicago,IL, USA

Certification:

  • American Board of Radiology (ABR)(Certified in Therapeutic Radiologic Physics in 2010)

Professional Associations:

2004-presentAmerican Physics Society (APS)

2006-presentAmerican Association of Physicists and Medicine (AAPM) (Member)

2009-presentAmerican Cancer Society on grant panel for Epidemiology and Clinical Research (Member)

Professional Activity:

2005Reviewer, Physica E-Low Dimensional Systems & Nanostructures

2006-presentReviewer, Medical Physics

2006-presentReviewer, Physics in Medicine and Biology

2007-presentReviewer, International Journal of Radiation Oncology-Biology-Physics

2008-presentReviewer, Medical & Biological Engineering & Computing

2008-presentGuest associate editor, Medical Physics

RESEARCH SUPPORT:

Completed Support

02/08 - 12/08DAMD17-02-1-0034,

Status: Complete, Principal Investigator

Support Source: Department of Defense Prostate Cancer Training Award

Title: "Real-Time Tracking of Implanted Markers during Radiation Treatment by Use of Simultaneous kV and MV imaging”

Amount: $120000

Ongoing Support

01/11 - 01/12Cancer Research Foundation Young InvestigatorAward,

Status:Principal Investigator

Support Source:Cancer Research Foundation

Title: "Dynamically Adaptive kV Aperture for Low Dose Real-Time Prostate Motion Tracking during Radiation Therapy by Combined MV-kV Imaging”

Amount: $75000

AWARDS:

Undergraduate Rutherford Scholarship, 1999

SFU Graduate Research Award, 2002

Full Financial PhD Deutsche Promotionstipendium (German Scholarship), 2002 - 2006

Basic Science Travel Grant to ASTRO’s 49th Annual Meeting, 2007

MAJOR RESEARCH INTERESTS:

Real-time organ motion tracking using on board LINAC MV and kV radiation imaging systems.

  • combined MV-kV 3D internal fiducial tracking
  • cone-beam reconstruction using multiple kV x-ray sources
  • adaptive kV beam aperture adjustment for target tracking and dose sparing

Molecular imaging and organ motion tracking techniques using iron oxided nano-particles.

  • magnetic field based localization of iron oxide fiducials using coil arrays (similar to Calypso)
  • magnetic particle molecular imaging techniques

Electronic portal imaging devices for tracking.

  • continuous real-time EPID imaging for organ motion tracking and dose verification
  • EPID segmentation algorithms for fiducials and organs
  • high speed EPID frame grabbing and image enhancement

TEACHING:

Teaching Assistant, SimonFraserUniversity, Vancouver, Canada 09/99 – 06/02

  • Phys. 131 entry level physics course targeted towards physics and engineering students.

Instructor, Max-Plank-Institute FKF, Stuttgart, Germany 06/02 – 05/06

  • Lecturer on low dimensional physics at the 14th International Winterschool on New Developments in Solid State Physics in Mauterndorf, Austria (2006).

Coordinator and Instructor, StanfordUniversity, Stanford, USA06/06

  • Coordinated the practical demonstration session of the Stanford Image Guided Radiation Therapy (IGRT) Short Course
  • Lectured on managing intra-fraction organ motion using 4D-CT, 4D-PET and IGRT treatment planning using Eclipse.
  • Gave a practical demonstration of gated treatment delivery including placement of RPM block, IMRT delivery using gating, patient positioning using EPID and/or OBI.

Instructor, The University of Chicago, Chicago, USA02/09 - Present

  • BIOS 29326: Introduction to Medical Physics. An advanced undergraduate course in medical physics.
  • MPHY 35100: Physics of Radiation Therapy, first year graduate course for medical physicists students.

MENTOR:

Undergraduate Honors Thesis Advisor, The University of Chicago, Chicago, USA 09/09 – 05/10

  • Superviser for Meredith Sadinski (Physics Major). Thesis title: Iron-oxide nanoparticle detection. Final grade: A-

GraduateThesis Advisor, The University of Chicago, Chicago, USA 01/10 – Present

  • Superviser for Zachary Grelewicz (Medical Physics Major).

PATENTS:

  1. Title: Using a Moving Imaging System to Monitor Anatomical Position as a Function oTime

Inventors: Wu Liu, Rodney D. Wiersma, Nadeem Raiz, Jing Wang, Lei Xing

Application number: 12/802,952

  1. Title: 3D real-time tracking of human anatomy using combined kV and MV imaging

Inventors: Rodney D. Wiersma, Lei Xing, Weihua Mao

Patent number: 8121368

PUBLICATIONS AND PRESENTATIONS:

Peer Review Articles

1.R. D. Wiersma, J. A. H. Stotz, O. J. Pitts, C. X. Wang, M. L. W. Thewalt, and S. P. Watkins, P-type carbon doping of GaSb, Journal of Electrical Materials, 30, 1429 (2001)

2.X. K. Chen, R. D. Wiersma, C. X. Wang, O. J. Pitts, C. Dale, C. R. Bolognesi, S. P. Watkins, Local vibrational mode of carbon in GaSb and GaAsSb, Applied Physics Letters, 80, 1942 (2002)

3.S. P. Watkins, R. D. Wiersma, C. X. Wang, O. J. Pitts, and C. R. Bolognesi, Structural Effects of Carbon in GaSb Grown by Metalorganic Vapor Phase Epitaxy, Journal of Crystal Growth (2003)

4.R. D. Wiersma, J. A. H. Stotz, C. X. Wang, M. L. W. Thewalt, and S. P. Watkins, Electrical and optical properties of carbon doped GaSb, Physical Review B, 67, 165202 (2003)

5.R. D. Wiersma, J. G. S. Lok, S. Kraus, W. Dietsche, K. von Klitzing, D. Schuh, M. Bichler, H. -P. Tranitz, and W. Wegscheider, Activated Transport in the Separate Layers that form the vT=1 Exciton Condensate, Physical Review Letters, 93, 266805 (2004)

6.R. D. Wiersma, J. G. S. Lok, S. Kraus, W. Dietsche, K. von Klitzing, et al., Activated Transport in the vT=1 Exciton Condensate at Balanced and Imbalanced Densities Measured in Drag and Counter-flow Configuration, Physica E, 34 (1-2): 16-21, (2006)

7.R. D. Wiersma, J. G. S. Lok, W. Dietsche, K. von Klitzing, D. Schuh, M. Bichler, H. -P. Tranitz, and W. Wegscheider, Role of density imbalance in the vT=1 exciton condensate state for electron bilayer systems, Physica Status Solidi, 243, No. 14, (2006)

8.R. D. Wiersma, J. G. S. Lok, L. Tiemann, W. Dietsche, K. von Klitzing, D. Schuh, M., W. Wegscheider, Investigations of the vT=1 exciton condensate, Physica E-Low Dimensional Systems & Nanostructures, 35 (2), 320-39)26, (2006)

9.R. D. Wiersma and L. Xing, Examination of Geometric and Dosimetric Accuracies of Gated Step-and-Shoot Intensity Modulated Radiation Therapy, Med. Phys., 34 (10), 3962 - 3970 (2007)

10.Wiersma, RD; Lok, JCS; Tiemann, L, W. Dietsche, K. von Klitzing. Investigations of the nu(T)=1 exciton condensate, INTERNATIONAL JOURNAL OF MODERN PHYSICS B, (21), 1256-1265 (2007)

11.R. D. Wiersma, W. Mao, and L. Xing, Combined kV and MV imaging for real-time tracking of implanted fiducial markers, Med. Phys., 35 (4), 1191-1198 (2008)

12.Mao W, Wiersma R. D., Xing L., Fast internal marker tracking algorithm for onboard MV and kV imaging systems, Med Phys., 35 (5), 1942-9 (2008)

13.Mao W, Riaz N, Lee L, Wiersma R, Xing L., A fiducial detection algorithm for real-time image guided IMRT based on simultaneous MV and kV imaging, Med. Phys., 2008 Aug;35(8):3554-64

14.Liu W, Wiersma R. D., Mao W, Luxton G, Xing L., Real-time 3D internal marker tracking during arc radiotherapy by the use of combined MV-kV imaging, Phys Med Biol., 53 (24), 7197-213 (2008)

15.R. D. Wiersma, N. Riaz, Sonja Dieterich, Yelin Suh, L. Xing, Use of MV and kV imager correlation for maintaining continuous real-time 3D internal marker tracking during beam interruptions,Phys Med Biol., 54 (1), 89-103 (2009)

16.Nadeem Riaz, Piyush Shanker, Rodney Wiersma, Olafur Gudmundsson, Weihua Mao, Bernard Widrow and Lei Xing, Predicting respiratory tumor motion with multi dimensional adaptive filters and support vector regression, Phys. Med. Biol., 54 (19), 5735-5748, (2009)

17.Weihua Mao, Annie Hsu, Nadeem Riaz, Louis Lee, Rodney Wiersma, Gary Luxton, Christopher King, Lei Xing, Timothy Solberg, Image-Guided Radiotherapy in Near Real Time With Intensity-Modulated Radiotherapy Megavoltage Treatment Beam Imaging, International Journal of Radiation Oncology * Biology * Physics, 75 (2), 603-610, (2009)

18.Wiersma RD, Wen Z, Sadinski M, Farrey K, Yenice KM. Development of a frameless stereotactic radiosurgery system based on real-time 6D position monitoring and adaptive head motion compensation. Phys Med Biol. 2010;55(2):389-401.

19.Liu Wu, Rodney D. Wiersma, Lei Xing, Optimized Hybrid MV-kV Imaging Protocol for Volumetric Prostate Arc Therapy, International Journal of Radiation Oncology * Biology * Physics, 78 (2), 595-604, (2010)

20. Ji Li, Rodney D. Wiersma, Christopher J. Stepaniak, Karl J. Farrey, and Hania A. Al-Hallaq, Improvements in dose accuracy delivered with static-MLC IMRT on an integrated linear accelerator control system,Med Phys., 39 (5), 2456-62 (2012)

21. Grelewicz Z, Kang H, Wiersma RD. An EPID based method for performing high accuracy calibration between an optical external marker tracking device and the LINAC reference frame,Med Phys., 39(5), 2771–2779 (2012)

22. H.J. Kang, Z. Grelewicz, and R.D. Wiersma, Development of an automated region of interest selection method for 3D surface monitoring of head motion, Med. Phys. 39, 3270 (2012)

23. Wiersma RD, Tomarken S.L., Grelewicz Z, Belcher A., Kang H, Feasibility of using Real-Time 3D Optical Surface Tracking for Robotic Motion Compensated Frameless SRS. Submitted to Phys. Med. Biol. (2012)

Book Chapters

1)Rodney D. Wiersma, Nadeem Riaz, and Lei Xing, Real-Time Imaging for Radiation Therapy Guidance, in Biomedical Mathematics: Promising Directions in Imaging, Therapy Planning, and Inverse Problems, Yair Censor, Ming Jiang, and Ge Wang (editors), Medical Physics Publishing, p509–542, 2010.

Published Abstracts

1)Wiersma, RD; Xing, L, Temporal, dosimetric, and geometric precision of gated step-and-shoot intensity modulated radiation therapy, MEDICAL PHYSICS Volume: 34 Issue: 6 Pages: 2601-2601 Published: JUN 2007

2)Wiersma, RD; Xing, L, Temporal precision of gated step-and-shoot intensity modulated radiation therapy, MEDICAL PHYSICS Volume: 34 Issue: 6 Pages: 2560-2560 Published: JUN 2007

3)Wiersma, RD; Xing, L, Dosimetric consequences of electronic delay on gated radiation therapy (RT), INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS Volume: 69 Pages: S131-S132 Published: 2007

4)Wiersma, RD; Mao, W; Riaz, N; Xing, L, Real-time tracking of implanted fiducial markers using combined kV and MV imaging, MEDICAL PHYSICS Volume: 35 Issue: 6 Pages: 2634-2634 Published: JUN 2008

5)Mao, W; Riaz, N; Lee, K; Wiersma, RD; King, C:Hsu, A; Luxton, G; Xing, L, Using Treatment Beam Imaging to Monitor Prostate Motion in Near Real-Time On a Conventional LINAC, MEDICAL PHYSICS Volume: 35 Issue: 6 Pages: 2634-2634 Published: JUN 2008

6)Wiersma, RD; Mao, W; Riaz, N; Xing, L, Use of Synchronized Beam Switching for Real-Time 3D kV-MV Internal Marker Tracking with Step-and-Shoot IMRT, MEDICAL PHYSICS Volume: 35 Issue: 6 Pages: 2598-2598 Published: JUN 2008

7)Riaz, N; Wiersma, RD; Mao, W; Xing, L, Improving Tracking of Implanted Radio-Opaque Markers on MV and kV Imaging with Techniques from Computer Vision and Machine Learning, MEDICAL PHYSICS Volume: 35 Issue: 6 Pages: 2618-2618 Published: JUN 2008

8)Wiersma, RD; Mao, W; Lee, K; Xing, L, Riaz, N, Tracking Multiple Moving Fiducials During Treatment Based on Simultaneous Onboard kV and Treatment MV Imaging, MEDICAL PHYSICS Volume: 35 Issue: 6 Pages: 2621-2621 Published: JUN 2008

9)Wiersma, RD; Mao, W; Xing, L; Luxton, G, Liu, W; Riaz, N, Nearly Real-Time Tumor Position Monitoring During Arc Therapy with Combined MV and kV Imaging, MEDICAL PHYSICS Volume: 35 Issue: 6 Pages: 2626-2626 Published: JUN 2008

10)Wiersma, RD; Mao, W; Xing, L; Riaz, N, Prediction of Fiducial Motion in Respiratory Tumors for Image-Guided Radiotherapy, MEDICAL PHYSICS Volume: 35 Issue: 6 Pages: 2626-2626 Published: JUN 2008

Oral Talks

1) P-type Carbon Doping of GaSb, Pacific Center for Advanced Materials and Microstructures (PCAMM) Conference, SimonFraserUniversity, (2001)

2) P-type Carbon Doping of GaSb, Canadian Association of Physics (CAP) Meeting, University of Victoria, (2001)

3) Activted Transport in the Separate Layers that form the ν=1 Exciton Condensate, Electronic Properties of Two-Dimensional System 16 (EP2DS-16), Albuquerque, New Mexico, (2005)

4) Investigations of the νT=1 Exciton Condensate and Possible Novel Devices,14th International Winterschool on New Developments in SolidState Physics, Mauterndorf, Austria, (2006)

5) Precision of Gated Step-and-Shoot Intensity Modulated Radiation Therapy,VisitingProfessor Research Symposium, Stanford, USA (2007)

6) Dosimetric Consequences of Electronic Delay on Gated Radiation Therapy (RT),49th Annual ASTRO Meeting, Los Angeles, USA (2007)

7) Dosimetric Precision of Gated Step-and-Shoot Intensity Modulated Radiation Therapy,49th Annual AAPM Meeting, Minneapolis, USA (2007)

8) Temporal Precision of Gated Step-and-Shoot Intensity Modulated Radiation Therapy,49th Annual AAPM Meeting, Minneapolis, USA (2007)

9) Real-time Tracking of Implanted Fiducial Markers using Combined Onboard kV Fluoroscopy and MV EPID Imaging,50th Annual ASTRO Meeting, Boston, USA (2008)

10) Managing intra-fraction organ motion I: 4D CT and IGRT treatment planning,Stanford IGRT Short Course, Stanford, USA (2008)