Curriculum Vitae

SONGSONG CAO

Department of Neurobiology

Duke University Medical Center

Box 3209

Durham, NC, 27710

(205) 348-9993

Name: SONGSONG CAO

Status: Postdoctoral researcher

Department: Neurobiology

Education: Institution and location Degree Year Field of study

Duke University Postdoc 2006-present Neurobiology

University of Alabama, Ph.D. 2000-2006 Biology

Tuscaloosa, Alabama

Nanjing University, China B.S. 1996-2000 Biochemistry

Professional

Experience: Research assistant, National Biochemical Engineering Laboratory, China, 1998

Research assistant, Institute of Metallurgical Chemistry, Chinese Academy of Sciences, China, 1999

Tutor for Biochemistry class BSC-439, at The Univeristy of Alabama, Fall, 2001.

Teaching assistant for Integrated Genetics class BSC-442, at The University of Alabama, Spring, 2002

Teacher for Introductory Biology class BSC-115, at The University of Alabama, Fall, 2002

Tutor for Genetics BSC 315 and Cell Biology BSC 300, at The University of Alabama, Spring, 2003

Presentations: 13Th International C. elegans Meeting, Los Angeles, 2001

41st American Society for Cell Biology Meeting, Washington, D.C., 2001

Midwest Worm Meeting, St. Louis, 2002

American Society for Cell Biology Meeting, San Francisco, 2002 (2 presentations)

Ubiquitin & Ubiquitin-like Modifications in Health & Disease Meeting, NIH, Bethesday, MD, 2003

14th International C. elegans Meeting, Los Angeles, 2003

Cell Biology of the Neuron, New Orleans, 2003

43rd American Society for Cell Biology Meeting, San Francisco, 2003 (3 presentations)

Society for Neuroscience Annual Meeting, San Diego, 2004

15th International C. elegans Meeting, Los Angeles, 2005

Gordon Research Conference on Stress Proteins in Growth, Development & Disease, Newport, RI, 2005

Guest

Lectures: Howard Hughes Medical Institute Undergraduate Research Interns Program class, March 2004

Howard Hughes Medical Institute Undergraduate Research Interns Program class, April 2005

Membership: American Society for Cell Biology

Society for Neuroscience

Publications: “Suppression of Polyglutamine-induced Aggregation in C. elegans by Torsin Proteins”. G. A. Caldwell, S. Cao, E. G. Sexton, C. C. Gelwix, J. P. Bevel and K. A. Caldwell. Human Molecular Genetics, February, 12 (3): 1-13, 2003.

“An animal model to discern torsin function: suppression of protein aggregation in C. elegans”. G. A. Caldwell, S. Cao, E. G. Sexton, C. C. Gelwix, J. P. Bevel and K. A. Caldwel. Adv Neurol. 94: 79-85, 2004

“Torsin-mediated protection from cellular stress in the dopaminergic neurons of C. elegans”. S. Cao, C. C. Gelwix, K. A. Caldwell, G. A. Caldwell. J Neurosci 25 (15): 3801-3812, 2005.

“Deletion of CHIP leads to caspase-3 activation and neuronal apoptosis associated with increase in non-ubiquitinated, soluble phosphor-tau species without neurofibrilllary tangles”. C. A. Dickey, D. Dickson, M. Yue, W-L Lin, J. Dunmore, G. West, C. Patterson, S. Cao, A. K. Clark, G. A. Caldwell, K. A. Caldwell, C. Eckman, M. Hutton, L. Petrucelli. J Neurosci 26 (26): 6985-6996, 2006.

“Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models”. AA Cooper, AD Gitler, A Cashikar, CM Haynes, KJ Hill, B Bhullar, K Liu, K Xu, KE Strathearn, F Liu, S Cao, KA Caldwell, GA Caldwell, G Marsischky, RD Kolodner, J Labaer, JC Rochet, NM Bonini, S Lindquist. Science, 313 (5785): 324-328, 2006.

“A C. elegans-based drug screen for torsinA effectors: implications for therapeutic development toward human movement disorders” S. Cao, A. C. Clark, K. A. Caldwell, G. A. Caldwell (Manuscript in preparation)

Book

Chapters: “Use of C. elegans to model human movement disorders”. Guy A. Caldwell, Songsong Cao, Iyare Izevbaye, and Kim A. Caldwell. In Animal Models of Movement Disorders, LeDoux, M. (ed.) Elsevier: New York.

Published

Abstracts: ] “In Vivo Suppression of Protein Aggregation by a C. elegans Torsin Homologue”. G.A. Caldwell, E.G. Sexton, S. Cao, J.P. Bevel, K.A. Caldwell. Movement Disorders, Vol. 17, No. 5: 1123, 2002.

Patents

Pending: “Methods of using small molecules for preventing protein misfolding and aggregation” No. 60/738, 761, 2005.

“Methods of using small molecule compounds for neuroprotection” No. 60/749, 910, 2005.

GPA: 3.75

GRE: 2210

Honors: People’s Scholarship, 1996-1997, Nanjing University, China

People’s Scholarship, 1997-1998, Nanjing University, China

Graduate Council fellowship, 2000-2001, The University of Alabama

Graduate Council fellowship supplement, 2000-2002, The University of Alabama

2001 GSA Travel Award, The University of Alabama

2001 SGA Travel Award, The University of Alabama

2001 American Society for Cell Biology Predoctoral Travel Award

2002 Graduate Student Research and Travel Support Award, The University of Alabama

2002 SGA Travel Award, The University of Alabama

Graduate Council Research and Creative Activity Fellowship, 2003-2004, The University of Alabama

Joab L. Thomas Scholarship, 2004-2005, The University of Alabama

Recipient of Excellence in Research by a Doctoral student in College of Arts and Sciences at The University of Alabama, 2004-2005

Recipient of Excellence in Research by a Doctoral student of The University of Alabama, 2004-2005

References: Dr. Janis O’Donnell, , 205-348-9810

Dr. Perry Churchill, , 205-348-4097

Dr. Guy Caldwell, , 205-348-9926