Table S2. Intestinal and systemic health biomarker values by assigned supplementation group in 18-month-old environmental enteric dysfunction (EED) study participants

Group / n / L:M,
Mean (SE)1 / MPO (ng/mL),
Mean (SE) / AAT (μg/mL),
Mean (SE) / NEO (nmol/L),
Mean (SE) / GLP-2 (ng/mL),
Mean (SE) / EndoCAb IgG (mu/mL),
Mean (SE) / CRP (mg/L),
Mean (SE) / AGP (mg/dL),
Mean (SE)
CFC-only / 102 / -2.70 (0.09) / 8.29 (0.09) / 5.63 (0.09) / 6.62 (0.08) / 1.10 (0.06) / 3.67 (0.10) / 0.23 (0.17) / 4.66 (0.03)
Chickpea / 120 / -2.93 (0.08) / 8.42 (0.08) / 5.72 (0.08) / 6.60 (0.07) / 1.05 (0.05) / 3.84 (0.09) / -0.07 (0.16) / 4.65 (0.03)
Plumpy'doz / 111 / -2.84 (0.08) / 8.50 (0.08) / 5.87 (0.08) / 6.78 (0.08) / 1.06 (0.05) / 3.89 (0.09) / 0.34 (0.16) / 4.66 (0.03)
Rice-lentil / 106 / -2.90 (0.08) / 8.45 (0.09) / 5.90 (0.09) / 6.60 (0.08) / 1.19 (0.05) / 3.81 (0.10) / 0.11 (0.17) / 4.67 (0.03)
WSB++ / 100 / -2.82 (0.08) / 8.34 (0.09) / 5.81 (0.09) / 6.63 (0.08) / 1.12 (0.06) / 3.85 (0.10) / 0.32 (0.17) / 4.61 (0.03)
P-value / 0.395 / 0.376 / 0.171 / 0.436 / 0.359 / 0.519 / 0.324 / 0.721

1Values are marginal means and standard errors from linear regression models with dependent variable log-transformed biomarker and indicator variables for the supplementation groups as independent variables. Abbreviations: AGP, α-1 acid glycoprotein; AAT, α-1 antitrypsin; CRP, C-reactive protein; CFC, child feeding counseling; EED, environmental enteric dysfunction; EndoCAb IgG, endotoxin core antibody immunoglobulin G; GLP-2, glucagon-like peptide-2; L:M, lactulose:mannitol ratio; MPO, myeloperoxidase; NEO, neopterin; WSB++, wheat-soy blend plus plus.