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CURRICULUM VITAE

I. PERSONAL DATA

Name PHILLIP LAWRENCE PEARL, M.D.

Address Department of Neurology

Children’s National Medical Center

111 Michigan Avenue, NW

Washington, DC 20010-2970

Telephone (202) 884-2120

Fax Number (202) 884-5226

E-mail Address

Date and place of birth: June 22, 1958

Baltimore, Maryland

Married: Maria Tartaglia Pearl, M.D.

Children: Melinda Erin Pearl (DOB 2/9/87)

Adam Timothy Pearl (DOB 3/10/89)

Suzanne Elizabeth Pearl (DOB 12/3/03)

Natalie Michelle Pearl (DOB 6/16/05)

II. EDUCATION

Undergraduate: B.A. with Honors (Natural Sciences) 1980

Johns Hopkins University

Baltimore, Maryland

Medical School: University of Maryland School of Medicine 1984

Baltimore, Maryland

Post-Graduate: Pediatric Internship and Residency, 1984-1986

Baylor College of Medicine, Houston, Texas

Chief of Service: Ralph D. Feigin, M.D.

Neurology and Child Neurology 1986-1989

Baylor College of Medicine, Houston, Texas

Chief of Service: Marvin A. Fishman, M.D.

Fellowship in Clinical Neurophysiology 1989-1990

Children's Hospital, Beth Israel Hospital,

Harvard Medical School, Boston, Massachusetts

Chief of Service: Gregory L. Holmes, M.D.

Graduate Certificate in Leadership Development 2003

Graduate School of Education and Human Development,

George Washington University, Washington, DC

III.  EMPLOYMENT HISTORY

CURRENT POSITION: Associate Professor of Pediatrics and Neurology

Director of Medical Student Education, Dept Neurology

The George Washington University School of Medicine and Health Sciences

Washington, D.C.

Chief of General Child Neurology

Director of Education, Department of Neurology

Member, Children’s Research Institute

Children's National Medical Center

Washington, D.C.

Special Volunteer 1997-Present

Clinical Epilepsy Branch

Office of the Clinical Director

Division of Intramural Research

National Institute of Neurological Disorders and Stroke

National Institutes of Health

Bethesda, Maryland

Scholar, Master Teachers Program in Medical Education

2002-2005

George Washington University School of Education

Medical Staff:

Children’s National Medical Center

Georgetown University Hospital

INOVA Fairfax Hospital

NIH Clinical Center

PRIOR POSITIONS AND ACADEMIC APPOINTMENTS:

Assistant Professor of Pediatrics and Neurology 1997-2002

George Washington University School of Medicine

Clinical Assistant Professor of Neurology and Pediatrics,

George Washington University School of Medicine 1990-97

Clinical Assistant Professor of Pediatrics and

Neurology 1990 - present

University of Maryland School of Medicine

Clinical Assistant Professor of Pediatrics (Neurology),

1994 – present, Clinical Instructor 1990-1994

Georgetown University School of Medicine

Visiting Associate Professor of Pediatrics 2006-present

Clinical Associate Professor of Pediatrics 2000-2006

Clinical Assistant Professor 1996-2000

University of Virginia School of Medicine

The Neurology Center 1990-1995

VA Neuroscience Center 1995-1997

INOVA Fairfax Hospital for Children

IV. LICENSURES: District of Columbia #18619 (8/17/90)

Virginia #0101 045295 (6/1/90)

CERTIFICATION:

American Board of Pediatrics, # 41010, 1989, re-certification 1996, 2004, exp 2010.

American Board of Psychiatry and Neurology, with Special Qualification in Child Neurology, # 784, 1991.

American Board of Clinical Neurophysiology 1993.

American Board of Psychiatry and Neurology, Subspecialty Certification in Clinical Neurophysiology, # 1139, 1999, exp 2009.

V.  HONORS AND AWARDS

Michael T. Ty Memorial Lecturer, Massachusetts General Hospital Department of Neurology, Boston 2008

“Best Doctors in America” 2007-2008.

“Outstanding Physicians,” Washingtons’ Consumer Checkbook 2007.

American Neurological Association, elected 2006.

American Pediatric Society, elected 2006.

America’s Top Physicians, Consumers’ Research Council of America 2004-2005.

Association of American Medical Colleges (AAMC) Faculty Award for Humanism in Medicine, Nominee from George Washington University School of Medicine 2004.

Board Examiner, American Board of Psychiatry and Neurology Oral Examinations 1999-present.

Local Host Chairman for Washington, DC examinations (2005, 2007)

Certificate of Appreciation for Outstanding Performance, Children’s Hospital, Washington, D.C. 2001.

Clinical Research Award Winner, Junior Faculty, Children’s Research Institute, 14th Annual Advances in Pediatrics, Children’s National Medical Center, May 4, 2000.

“Top Doctors”, Washington Area Specialists, Washingtonian Magazine 2008, 2005, 2002, 1999, 1995.

“Best Specialists”, Consumer Checkbook Magazine, Washington, D.C., 1998, 1995.

Physician’s Recognition Award, American Medical Association 1996.

Certificate of Appreciation, Autism Society of America 1990.

Award for Top Score, Epilepsy Mini-Fellowship Program, J.K. Penry, M.D. 1989

Bowman-Grey School of Medicine.

American Academy of Neurology Medical Student Essay Contest, Honorable Mention: Spontaneous Regression of Stage IV-S Neuroblastoma 1984.

Henry Zoller, Jr., Scholarship Award, 1978 Johns Hopkins University.

PROFESSIONAL SOCIETIES/COMMITTEES:

NATIONAL

American Academy of Pediatrics (Fellow, FAAP) 2000-present

American Academy of Neurology

Councilor, Child Neurology Section 2006-2008

A.B. Baker Education Section 2000 – present.

Child Neurology Section 1999 – present.

Counselor to Child Neurology Section, elected 2005.

Epilepsy Section 1999 – present.

American Board of Psychiatry and Neurology

Committee on Written Examination (Neurology questions for Psychiatry examination) 2003- present.

Committee on Written Examination (Child Neurology examination) 2005-present.

American Clinical Neurophysiology Society 1989-present (elected Fellow 2005)

American Epilepsy Society

Practice Committee 2000-2003.

CME Review Committee 2006-present.

Program Committee 2006-present.

American Sleep Disorders Association 1998-2006

American Society for Experimental NeuroTherapeutics 2004-2006.

CDGS (Congenital Disorders of Glycosylation) Family Network, Medical Advisory Board

Child Neurology Foundation

Career Development Committee 2002 – present.

Medical Student Scholarship Committee 2004-present.

Executive Board 2006-present.

Child Neurology Society 1989 – present.

Awards Committee 2003 – present.

Chairman, Awards Committee 2004 – present.

Data and Safety Monitoring Board, Cooperative Internatl Neuromuscular Research Group, 2000-2003.

Doctors Opposed to Child Soldiers (DOCS) 2000

National Capital Cure Epilepsy Conference, Steering Committee 2004.

Pediatric Neurotransmitter Diseases (PND) Association, Medical and Scientific Advisory Board

Professors of Child Neurology 2004-present.

Secretary-Treasurer, elected 2006.

REGIONAL

Epilepsy Foundation of America, National Capital Area, Professional Advisory Board

Fairfax County Medical Society

National Down's Syndrome Congress, National Professional Advisory Board

Northern Virginia Pediatric Society

Tourette Syndrome Association

Virginia Neurological Society

VI.  ADMINISTRATIVE DUTIES AND UNIVERSITY ACTIVITIES

George Washington Universtiy School of Medicine and Health Sciences

Admissions Office Interviews 2002 – 2004

Faculty Senate, Department of Neurology 2003 – present

Year 3-4 Curriculum Committee 2001-present

Children’s National Medical Center

Graduate Medical Education Committee 2003-present.

Graduate Medical Education Executive Committee 2007-present

Institutional Ethics Forum, CNMC, 2004 – 2007

Physician Liasion and Planning Committee, Jazzmatazz, Development Office 2000-2006

Search Committee, Chairman of Pulmonary Department 2001

Specialty Services to Emergency Department Task Force 2000 – 2003

Regional Hospitals

Child Abuse Committee, Arlington Hospital 1997-1998

Education Committee, Chairman, Section of Neruology, INOVA Fairfax Hospital 1997-1998

Education Committee, Co-chairman, Section of Neurology, Fairfax Hospital 1994 – 1997

Neurophysiology Technology Committee, Section of Neurology, Fairfax Hospital 1993-1994

VII.  EDUCATIONAL ACHIEVEMENTS

A.  Courses Taught

1.  Director, ICM (Introduction to Clinical Medicine): Neurology Portion, GWU 2nd Year Medical School Course, 2001-present.

2.  Lecturer, Neurology Update Course, CNMC:

  1. Genetics of Sleep Disorders 1998
  2. Biological Basis of Autism 1999
  3. Sleep Disorders in Children 2000
  4. Sleep Investigations 2001
  5. Therapies in Sleep Disorders of Childhood 2002
  6. Alternative Medicines in Epilepsy 2003
  7. Seizures and Metabolic Disease2004
  8. Case Studies in Neurogenetics: Diagnostic Dilemmas 2005
  9. Neurology of Famous Musicians: In Words and Music 2006
  10. Biological Basis of Autism 2007
  11. Moderator of General Child Neurology Session 2008

3.  Neurology Lecturer: Pediatric Board Review Course, CNMC 1998-present.

4.  Lecturer: Seizures and Epilepsy, GWU 3rd Year Pediatrics Rotation, CNMC 2000-2004

5.  Lecturer: Headaches, GWU 3rd Year Pediatrics Rotation, CNMC, 2001-2004

6.  Lecturer: Introduction to Practice of Medicine Course, GWU School of Medicine, 2001-present.

  1. Neurological Examination
  2. Neurology Case Vignettes
  3. Localization in the Nervous System
  4. Epilepsy
  5. Congenital Brain Development

7.  Intake Attending, CNMC Pediatric Residency Program, 2000-2004

8.  Walk Rounds Teaching Attending, GWU Medical Students, 1998-2005

9.  Professorial Rounds, CNMC, Pediatric Residency Program

  1. Neurocutaneous Syndromes 2000
  2. Gait Dysfunction 2001
  3. Encephalitis 2003
  4. Complex partial seizures 2006

10.  Preceptor and Director: Localization in the Nervous System, Dept. Neurology, CNMC 1997-Present.

11.  Program Director, Institutionalization and the Brain: The Internationally Adopted Child, CNMC, Oct 14-16, 1998.

B.  New Courses or Programs Developed

1.  Director, Neurology Clerkship Year IV, GWU School of Medicine, July 2004- present.

2.  Director, Neurology Fellowship Training Program, CNMC 2002-present.

3.  Coordinator, Neurology Fellowship Training Program, CNMC 1997-2002.

4.  Program Director: CNMC Pediatric Neurology CME (Mary Washington Hospital) 2007

5.  Seminar on Neurology in Great Musicians: In Words and Music. Annual Meeting of the Child Neurology Society 2006, 2007

6.  Combined Neuropharmacology Elective for MS IV students: Mechanisms of Epilepsy and Antiepileptic Therapy with Timothy Hales PhD, Dept. Pharmacology, GWU 2007.

7.  Use and Misuse of Alternative and Complementary Medicines in Epilepsy, Annual Meeting of the American Academy of Neurology, with Joan Conry MD, Denver, CO 2002, Honolulu, HA 2003, San Francisco, CA 2004.

8.  Program Director, Institutionalization and the Brain: The Internationally Adopted Child, CNMC 1998.

C.  Students mentored as primary advisor

1.  Sophie Rich, Yale University Undergraduate, Epilepsy Research Program, Summer 2000, CNMC, cf publications: Sleep Medicine 2002, and abstracts 39, 43.

2.  Elizabeth Allen, Yale University Undergraduate, Epilepsy Research Program, Summer 2000, CNMC, cf publications: Epilepsy 2000; 3:9-11, and abstracts 39, 43.

3.  Amanda Stahl, Cornell University Undergraduate, Epilepsy Research Program, Summer 2000, CNMC, cf publications: abstracts 39, 43.

4.  Molly Galgano MS IV, GWU School of Medicine, Senior project: Assessment of EEG Characteristics in Patients with Landau-Kleffner Syndrome 2001.

5.  Emily Robbins, Georgetown University Undergraduate, Research Project: Clinical Database and Antiepileptic Drug Treatments in the Murine Model of SSADH Deficiency, Summer 2003. Research published in the Georgetown Undergraduate Science Bulletin 2004.

6.  Sarah Reece-Staunton, GWU Medical Student, Project: Alternative Therapies in Epilepsy, Winner of Joseph Collins Scholarship Award for Medical Students interested in careers in neuroscience 2003.

7.  Philip Cap, MD 2005, GWU Medical Student, Project: Pediatric Sleep Disorders: Seminars in Primary Care (publication 2005); Pediatric Neurotransmitter Diseases (publication 2005); Methylphenidate Pharmacology and Therapy (publication 2005).

8.  Heather D. Bennett, BA, Johns Hopkins Postbaccalaureate Premedical Student, Research in Pediatric Neurotransmitter Diseases, Sept 2004-June 2005; matriculates into medical school Fall 2005.

9.  Jessica Cabalza, BA, Johns Hopkins Postbaccalaureate Premedical Student, Research in Pediatric Neurotransmitter Diseases and Educational Coordinator, July 2005-present.

10.  Thomas Hartka, BA, Johns Hopkins Postbaccalaurate Premedical Student, Research in Neurogenetics, February 2006 – present.

11.  Elizabeth Molloy, BA, MD 2006, GWU Medical Student, Research Elective: MRI abnormalities associated with vigabatrin therapy; Dorsal midbrain MRI abnormalities in acute encephalopathies; Pontocerebellar hypoplasia in neurocutaneous hypermelanosis; February/March 2006.

12.  Stacey Trzcinski, MS III-IV, University of Pittsburgh School of Medicine, Research Year 2006-2007 in conjunction with NIH sponsored GCRC research program for medical students.

13.  Jacob Taylor BA Yale University, Johns Hopkins Postbaccalaureate Premedical School, Research and Education Coordinator, 2006-2007.

14.  Alexander Sokohl BA Duke University, Johns Hopkins Postbaccalaureate Premedical Program, Research Assistant in Neurogenetics 2006-2007.

15.  Peter Peloquin BA, MS, Johns Hopkins Postbaccalaureate Premedical School, Research and Education Coordinator, 2007-2008.

16.  Janis Sethness BA, Johns Hopkins Postbaccalaureate Premedical Program, Research Assistant in Neurogenetics 2007-2008.

17.  Jennifer Pettiford MA, MS III, GWU School of Medicine, Clinical Research Year 2008-2009.

18.  Katherine Forester BA, Johns Hopkins Postbaccalaureate Premedical School, Research and Education Coordinator, 2007-2008.

D.  Educational Awards

Distinguished Teacher Award 2005, George Washington University School of Medicine

Master Teacher Certificate in Medical Education, Children’s National Medical Center and George Washington University Medical Center, June 30, 2003.

Certificate in Leadership Development, Graduate School of Education and Human Development, George Washington University, May 15, 2003.

Teacher Recognition Certificate, American Academy of Neurology 2002.

Outstanding Teacher Commendation, 1990 Harvard-Longwood Neurology House Staff

Children's Hospital, Harvard Medical School.

Outstanding Teacher Commendation, 1987 Dept. Neurology, Baylor College of Medicine.

E.  Training of Graduate Students/Post Doctoral as Program Director

1.  1997-2000 Kimberly Krohn MD, Pediatric Neurology Fellow; Current: Staff Neurologist, Duluth Clinic, Duluth, MN

2.  1998-2001 Susanne Schmandt MD, Pediatric Neurology Fellow; Current: Child Neurology Clinic, Germany

3.  1999-2002 Tena Rosser MD, Pediatric Neurology Fellow; Current: Assistant Professor of Pediatrics and Neurology, GWU, CNMC 2002-2004; Children’s Hosp Los Angeles 2004-present.

4.  1999-2002 Sylvia Mandler MD, Pediatric Neurology Fellow; Current: Pediatric Neurology practice, Bethesda, MD.

5.  2000-2003 Taeun Chang MD, Pediatric Neurology Fellow; Current: Assistant Professor of Pediatrics and Neurology, GWU, CNMC

6.  2000-2003 Maria Acosta, MD, Pediatric Neurology Fellow; Current: Pediatric Residency, GWU, CNMC; Clinical Fellow in SSADH Deficiency Research 2004-2005; Current: Assistant Professor, GWU, CNMC..

7.  2001-2004: Adeline Vanderver MD, Pediatric Neurology Fellow; Current: Assistant Professor, GWU, CNMC.

8.  2002-2005: William Benko MD, Pediatric Neurology Fellow; Current: Practice, Hershey, PA.

9.  2003-2006: Janet Lam MD, Pediatric Neurology Fellow; Current: Dept Neurology, Univ Maryland School of Medicine, Baltimore, MD.

10.  2003-2006: John Crawford MD, Pediatric Neurology Fellow; Current: NSADA fellow, CNMC.

11.  2003-2004: Denise Wallis MD, Post-doctoral Research in Pediatric Neurotransmitter Diseases; Current: Psychiatry Residency for 7/04, Chicago Medical School.

12.  2004-2007: Tarannum Lateef MD, Pediatric Neurology Fellow; Current: Assistant Professor, GWU, CNMC.

13.  2004-2007: Jessica Carpenter MD, Pediatric Neurology Fellow; Current: Assistant Professor, GWU, CNMC.

14.  2005-2008: Joseph Scafidi DO, Pediatric Neurology Fellow; Current: Instructor, GWU, CNMC.

15.  2005-2008: David Hsieh MD, Pediatric Neurology Fellow; Current: San Antonio, TX, US Air Force, Chief of Neurogenetics Clinic.

16.  2005-2008: Kevin DeBrangca MD, Pediatric Neurology Fellow; Current: Fellow, Memorial Sloan Kettering Institute, New York, NY.

17.  2006: Ana Roche Martinez MD, Visiting Pediatrician from Spain, Clinical Research summer program.

18.  2007-present: Emily Freilich MD, Pediatric Neurology Fellow

19.  2007-present: Carolina Tesi-Rocha MD, Pediatric Neurology Fellow

20.  Oct-Dec 2007: Ina Knerr MD, Visiting Scientist-Metabolic Pediatrician, Nuremberg-Erlangen Children’s Hospital: SSADH research.

21.  May 2008: Yana Jane Tavyev MD, Visiting Neurodevelopmental Disabilities Resident from Baylor College of Medicine, Houston, TX

22.  2007-2008: Ari Heffron MD, Research Coordinator for NIH R-01 Study: Levetiracetam for the Prevention of Post-traumatic Seizures, Current: Resident in Obstetrics/Gynecology, Wayne State University, Detroit, MI.

VIII.  CONSULTANT APPOINTMENTS

National Tuberous Sclerosis Alliance Mid-Atlantic Region Clinic,

Fairfax, VA 1996 – present (voluntary).

School for Contemporary Education, Neurology Educator and Consultant, Fairfax, VA 1992-1996 (voluntary).

Hospital Consulting Privileges: NIH Clinical Center, Bethesda, MD

Georgetown University Hospital, Wash., DC

INOVA Fairfax Hospital for Children, Fairfax, VA

IX.  RESEARCH PROTOCOLS/GRANTS/CONTRACTS AWARDED

(In chronological order)

Pearl PL. Clinical Studies on SSADH Deficiency,” Pediatric Neurotransmitter Disease Association $ 40,000, 2007-2009.

Pearl PL. Cerebral MRI Abnormalities Associated with Vigabatrin Therapy. CNMC IRB #3953, approval 12/5/06.

Pearl PL. Master Teacher Funding Bridge Award, CNMC Department of Medical Education. 0.1 support award 2005-2006; $ 15,000 award on competitive renewal 2006-2007.

Conry JA (PI), Gaillard WD, Lavenstein B, Pearl PL, Tsuchida TN, Weinstein SL, Moorjani B. A Double-Blind, Placebo-Controlled, Parallel-Group Study of Rufinamide given as Adjunctive Therapy in Paitents with Refractory Partial Seizures. Eisai Global Clinical Development, IRB submission 10/06.