TEACHING & ASSESSMENT PLAN

1. College : Engineering College

2. Department : Chemical Engineering

3. Semester : Spring 2010-2011

4. Course Code : CHPE 422

5. Course Name : Bioreactors Engineering

6. Time Table : Day Time Class Room

Sunday / 11:00 AM-12:15 PM / 4-14
Tuesday / 11:00 AM-12:15 PM / 4-14

7. Faculty Name : Sagheer Onaizi

8. Office No. : 5D-40

9. E-mail :

10. Time for office hours : Day Time

Sat, Mon, Wed / 10:00-15:00

11. Text Book & References :

Text Book / References
Shuler M.L. and Kargi F. “Bioprocess Engineering: Basic Concepts” Prentice Hall 2nd Edition (2002) / 1.  Bioprocess Engineering Principles, Doran, Academic Press, 2006.
2. Biochemical Engineering, Blanch and Clark, Marcel Decker, 1997.

12. Course Description

This course deals with the engineering, biochemical, and physiological considerations in the design of bioreactor processes: enzyme kinetics, mass transfer limitations, microbial growth, and product formation kinetics. fermentation reactor selection, design, scale-up, control.

13. Learning Outcomes

At the end of this course
Upon completion of this course, students shall be able to:
·  Quantitatively analyze enzyme systems.
·  Quantitatively describe the growth of microorganisms.
·  Determine the reaction stoichiometry for bioreactors.
·  Select, scale up, and understand the operation of
Bioreactors.
·  Learn principles of bioreactor analysis and design.
·  Develop sufficient skills to read current literature in
the bioreactors field and pursue further understanding
of the material.
·  Understand where the field is heading and identify
future opportunities.

14. Assessment Policy

Assessment process takes direct and indirect measurements to ensure that learning outcomes and program objectives have been achieved. The assessment includes assignments, quizzes, tests, projects and discussions. The type of assessment is indicated in the weekly plan table and the assessment details are as follows:

Assessment Details:

Assessment / Percentage % / Due
Assignments / 10%
Project / 10%
Quizzes / 10 %
Two Midterm Exams / 30%
Final Exam / 40% / Final Exam

15. Plagiarism policy

As per the University Policy UoN-STC-CR-1-2009, the following actions(not limited to), without proper attribution (quoting and/or referencing), will attract stringent penalties:
1.  copy the work of another student;
2.  directly copy any part of another person’s work;
3.  summaries another person’s work;
4.  use or develop an idea or thesis derived from another person’s work; or
5.  use experimental results or data obtained or gathers by another person.
6.  cheating during exam

16. Attendance policy

As per the University Absentee Regulations Uon-RR-AP-1-2009, Absentee warning notice will be issued to the student according to:
1.  “Absentee Warning 1” has to be issued to student who has missed 5% of course contact hours.
2.  “Absentee Warning 2” has to be issued to student who has missed 10% of course contact hours.
3.  “Drop one Grade” has to be issued to student who has missed 15% of course contact hours.
4.  “Barred from Examination” has to be issued to student who has missed 25% of course contact hours.

17. Weekly Teaching & Assessment Plan:

Week No. / Title / Course Outcome / Assessment of Outcomes
1.  / Introduction and Basics of Cell Biology and Biochemistry: Eukaryotic and Prokaryotic cells, Structural characteristics of a bacterial cell, Bacteria (cell) growth, Gram staining, Nutration and growth. / To get acquainted with the basic concepts and terminologies of Bioprocess Engineering and also to be able to differentiate between different types of cells.
2. 
3.  / Enzymes kinetics : Amino acids and protein, How Enzymes work, Simple Enzyme kinetic, Michel-Menten kinetic model, Steady state assumptions, Inhibited enzyme kinetics, Effect of pH and temperature, Immobilized enzyme system.
. / To be able to understand the kinetics of enzymatic reactions and also the ability to derive the reaction rate based on different models both for free and immobilized enzymes. / Assignment/Quiz
4. 
5. 
6. 
7.  / How Cells grow: Cell Growth, Batch Growth Kinetics, Product formation kinetics, Nutrient limitation, Ideal Chemostat, Modeling approaches. / To understand the relationship between the different forms of energy in terms of heat and work and the applications of the first law of thermodynamics / Assignment/Quiz
8. 
9. 
10. 
11.  / Operating Considerations for Bioreactors for Suspension and immobilized Cultures: choosing the cultivation method, modifying batch and continuous reactors, multistage chemostat systems, fed batch operation, immobilized cell systems / To be able to select the best cultivation method for suspended and immobilized cell culture and also to be able to design/modify different types of bioreactors based given operational conditions / Assignment/Quiz
12. 
13. 
14.  / Scale-Up and Optimization of Bioreactors: Oxygen Mass Transfer and Mixing (agitation and aeration), Selection, scale-up, operation, and control of bioreactors. / To be able to differentiate between different types of bioreactor and to make the appropriate selection of a reactor based the given conditions. It is also to be able to optimize the design of bioreactors taking into consideration reaction and mass transfer limitations / Assignment/Quiz
15.