Table S1. Summary of identified genes from Ridgeia piscesae

Accession
no. / Sequence homology / amino acid
identity / E
value / Accession no.
of similar protein / cl-
on-
es
Adaptation and Defence Related Proteins
EV802526 / myohemerythrin [Theromyzon tessulatum] / 36/62 (58%) / 2e-14 / AAG01808 / 1
EV802527 / myohemerythrin isoform I
[Phascolopsis gouldii] / 72/118 (61%) / 2e-37 / AAB22826 / 1
EV802528 / myohemerythrin [Theromyzon tessulatum] / 40/67 (59%) / 4e-17 / AAG01808 / 1
EV802529 / myohemerythrin [Sipunculus nudus] / 25/38 (65%) / 4e-07 / CAG14944 / 1
EV802562 / exoskeleton beta-chitin-specific binding protein [Riftia pachyptila] / 106/167 (63%) / 1e-63 / AAF76890 / 90
EV802563 / exoskeleton beta-chitin-specific binding protein / 48/132 (36%) / 5e-20 / AAF76890 / 44
EV802564 / exoskeleton beta-chitin-specific binding protein / 35/89 (39%) / 2e-10 / AAF76890 / 1
EV802566 / exoskeleton beta-chitin-specific binding protein / 64/141 (45%) / 2e-30 / AAF76890 / 2
EV802567 / exoskeleton beta-chitin-specific binding protein / 89/142 (62%) / 3e-50 / AAF76890 / 1
EV802568 / exoskeleton beta-chitin-specific binding protein / 98/157 (62%) / 4e-54 / AAF76890 / 2
EV802569 / exoskeleton beta-chitin-specific binding protein / 106/167 (63%) / 2e-64 / AAF76890 / 2
EV802570 / exoskeleton beta-chitin-specific binding protein / 33/90 (36%) / 7e-11 / AAF76890 / 1
EV802571 / exoskeleton beta-chitin-specific binding protein / 67/154 (43%) / 3e-22 / AAF76890 / 1
EV802572 / exoskeleton beta-chitin-specific binding protein / 53/101 (52%) / 2e-23 / AAF76890 / 1
EV802575 / exoskeleton beta-chitin-specific binding protein / 84/170 (49%) / 1e-37 / AAF76890 / 4
EV802576 / exoskeleton beta-chitin-specific binding protein / 54/154 (35%) / 2e-22 / AAF76890 / 3
EV802577 / exoskeleton beta-chitin-specific binding protein / 80/166 (48%) / 4e-40 / AAF76890 / 22
EV802578 / exoskeleton beta-chitin-specific binding protein / 46/128 (35%) / 2e-13 / AAF76890 / 1
EV802579 / exoskeleton beta-chitin-specific binding protein / 63/201 (31%) / 4e-10 / AAF76890 / 15
EV802580 / exoskeleton beta-chitin-specific binding protein / 28/89 (31%) / 8e-06 / AAF76890 / 1
EV802581 / exoskeleton beta-chitin-specific binding protein / 58/173 (33%) / 5e-15 / AAF76890 / 1
EV802582 / exoskeleton beta-chitin-specific binding protein / 37/114 (32%) / 1e-09 / AAF76890 / 1
EV802583 / exoskeleton beta-chitin-specific binding protein / 81/166 (48%) / 6e-41 / AAF76890 / 11
EV802584 / exoskeleton beta-chitin-specific binding protein / 36/91 (39%) / 4e-13 / AAF76890 / 1
EV802585 / exoskeleton beta-chitin-specific binding protein / 55/163 (33%) / 2e-14 / AAF76890 / 5
EV802586 / exoskeleton beta-chitin-specific binding protein / 58/173 (33%) / 5e-15 / AAF76890 / 15
EV802587 / exoskeleton beta-chitin-specific binding protein / 29/119 (24%) / 5e-04 / AAF76890 / 1
EV802588 / chitinase 7 [Tribolium castaneum] / 40/70 (57%) / 1e-17 / ABG47445 / 1
EV802589 / lysozyme [Eisenia fetida] / 70/123 (56%) / 3e-40 / ABC68610 / 1
EV802590 / lysozyme [Eisenia fetida] / 72/120 (60%) / 1e-40 / ABC68610 / 1
EV802591 / fibrinogen and fibronectin [Aedes aegypti] / 29/79 (36%) / 7e-06 / EAT44910 / 1
EV802593 / heat shock protein 20.6 [Locusta migratoria] / 23/79 (29%) / 4e-05 / ABC84493 / 1
Cell Proliferation Related Proteins
EV802594 / TNF receptor-associated protein 1 [Danio rerio] / 74/125 (59%) / 1e-36 / XP_695428 / 1
EV802595 / breast carcinoma amplified sequence 2 variant [Homo sapiens] / 144/201 (71%) / 2e-71 / BAD96357 / 1
EV802596 / tumor suppressor [Suberites domuncula] / 21/27 (77%) / 2e-04 / CAC80049 / 1
EV802597 / B-cell receptor-associated protein 37
[Tribolium castaneum] / 69/91 (75%) / 1e-32 / XP_974101 / 1
EV802598 / prohibitin [Strongylocentrotus purpuratus] / 52/72 (72%) / 1e-20 / XP_001178147 / 1
EV802599 / prohibitin protein WPH [Bombyx mori] / 116/150 (77%) / 7e-56 / ABD36375 / 1
EV802600 / B-cell translocation gene 1, anti-proliferative, isoform CRA_a [Homo sapiens] / 32/62 (51%) / 5e-11 / EAW97466 / 1
EV802601 / lipoma HMGIC fusion partner-like 3
[Danio rerio] / 104/196 (53%) / 4e-59 / CAK11284 / 1
EV802602 / Sdccag1 protein [Rattus norvegicus] / 61/100 (61%) / 5e-29 / AAH89999 / 2
Signal Transduction and Cyclins
EV802603 / cyclic AMP-regulated protein
[Marsupenaeus japonicus] / 80/143 (55%) / 5e-39 / BAB85575 / 1
EV802604 / guanine nucleotide binding protein
[Lethenteron japonicum] / 176/192 (91%) / 2e-103 / BAE93065 / 1
EV802605 / cloned by ability to arrest the cell cycle when expressed in the fission yeast Schizosaccharomyces pombe / 67/78 (85%) / 3e-30 / AAA03464 / 1
EV802606 / Nuclear receptor binding protein
[Xenopus tropicalis] / 81/102 (79%) / 1e-41 / AAH74684 / 1
EV802607 / anaphase-promoting complex subunit 4 isoform 2 [Danio rerio] / 99/296 (33%) / 3e-18 / XP_707691 / 1
EV802608 / inosine triphosphatase [Mus musculus] / 130/187 (69%) / 5e-76 / NP_080198 / 1
EV802609 / BolA [Aedes aegypti] / 59/111 (53%) / 9e-24 / EAT44928 / 1
EV802610 / casein kinase 2 beta polypeptide
[synthetic construct] / 187/191 (97%) / 5e-98 / AAX37079 / 1
EV802611 / thymidine kinase 2 [Mus musculus] / 92/237 (38%) / 7e-46 / AAF08104 / 1
EV802612 / chemotaxin [Oncorhynchus mykiss] / 91/129 (70%) / 7e-44 / AAG28030 / 1
EV802613 / S100-like calcium binding protein
[Salvelinus fontinalis] / 70/93 (75%) / 1e-25 / AAC28367 / 1
EV802614 / differentially regulated trout protein 1 [Pseudosciaena crocea] / 86/88 (97%) / 3e-39 / ABE02825 / 1
EV802615 / differentially regulated trout protein 1 [Pseudosciaena crocea] / 57/87 (65%) / 1e-21 / ABE02825 / 1
Basal Metabolism
EV802484 / cytochrome c oxidase subunit 1
[Riftia pachyptila] / 365/397 (91%) / 0.0 / AAU20751 / 14
EV802485 / cytochrome c oxidase subunit 3
[Riftia pachyptila] / 167/190 (87%) / 7e-73 / AAU20754 / 4
EV802487 / cytochrome c oxidase subunit IV [Bombyx mori] / 48/101 (47%) / 1e-16 / ABF51243 / 1
EV802488 / cytochrome c oxidase polypeptide Vb
[Ixodes scapularis] / 60/136 (44%) / 2e-27 / AAY66932 / 2
EV802489 / cytochrome c-1 isoform 1 [Danio rerio] / 184/298 (61%) / 1e-99 / XP_686816 / 2
EV802490 / cytochrome oxidase subunit VIIc
[Ixodes pacificus] / 33/72 (45%) / 2e-09 / AAT92215 / 2
EV802491 / cytochrome c oxidase subunit VIIc [Danio rerio] / 55/61 (90%) / 3e-25 / AAH59638 / 1
EV802492 / cytochrome c oxidase subunit Vic [Lama pacos] / 38/70 (54%) / 3e-15 / ABG66313 / 2
EV802493 / cytochrome c oxidase subunit Va
[Ixodes pacificus] / 76/103 (73%) / 2e-40 / AAT92214 / 1
EV802494 / cytochrome c oxidase subunit Via
precursor [Thunnus obesus] / 54/89 (60%) / 3e-26 / AAF04404 / 4
EV802495 / ubiquinol-cytochrome c reductase,
complex III subunit VII [Danio rerio] / 42/83 (50%) / 8e-19 / AAH76310 / 3
EV802496 / ubiquinol-cytochrome c reductase
complex [Xenopus tropicalis] / 32/61 (52%) / 5e-12 / CAJ82412 / 1
EV802497 / ubiquinol-cytochrome c reductase binding protein [Danio rerio] / 84/111 (75%) / 2e-42 / CAK10736 / 1
EV802498 / smallest subunit of ubiquinol- cytochrome c reductase [Gallus gallus] / 24/52 (46%) / 1e-06 / XP_001233456 / 1
EV802992 / cytochrome P450 [Aedes aegypti] / 21/56 (37%) / 0.91 / EAT35039 / 1
EV802499 / NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3 [Gallus gallus] / 34/90 (37%) / 2e-09 / XP_421934 / 1
EV802500 / NADH-ubiquinone oxidoreductase
[Ixodes ricinus] / 76/125 (60%) / 2e-36 / AAQ21387 / 2
EV802501 / NADH:ubiquinone dehydrogenase
[Aedes aegypti] / 38/107 (35%) / 2e-11 / EAT45921 / 3
EV802502 / NADH ubiquinone oxidoreductase subunit [Aedes aegypti] / 51/104 (49%) / 2e-20 / EAT47699 / 2
EV802503 / NADH dehydrogenase subunit 2
[Riftia pachyptila] / 204/289 (70%) / 6e-71 / AAU20750 / 2
EV802504 / NADH dehydrogenase 1 alpha
subcomplex-like [Ixodes scapularis] / 57/96 (59%) / 4e-25 / AAY66914 / 1
EV802505 / NADH dehydrogenase (ubiquinone) Fe-S protein 4 [Mus musculus] / 88/160 (55%) / 8e-44 / AAH04618 / 2
EV802506 / NADH:ubiquinone oxidoreductase b17.2 subunit isoform 1 [Gallus gallus] / 67/141 (47%) / 2e-33 / XP_001231740 / 1
EV802507 / NADH dehydrogenase (ubiquinone) flavoprotein 1 [Rattus norvegicus] / 100/134 (74%) / 4e-56 / AAH83709 / 1
EV802508 / NADH dehydrogenase [Aedes aegypti] / 29/75 (38%) / 5e-07 / EAT37314 / 1
EV802509 / NADH dehydrogenase subunit 3
[Riftia pachyptila] / 34/53 (64%) / 5e-23 / AAU20749 / 1
EV802511 / NADH dehydrogenase (ubiquinone)
[Gallus gallus] / 29/35 (82%) / 2e-10 / XP_001232780 / 1
EV802512 / NADH-ubiquinone oxidoreductase sgdh subunit [Aedes aegypti] / 77/179 (43%) / 1e-33 / EAT39093 / 1
EV802513 / NADH:ubiquinone dehydrogenase
[Aedes aegypti] / 32/90 (35%) / 2e-08 / EAT45921 / 1
EV802514 / ubiquitin [Branchiostoma belcheri] / 101/105 (96%) / 3e-54 / AAK91296 / 1
EV802515 / ubiquitin [Branchiostoma belcheri] / 122/128 (95%) / 1e-65 / AAK91296 / 1
EV802516 / ubiquitin/ribosomal protein S30e fusion protein [Carabus granulatus] / 62/73 (84%) / 1e-20 / CAJ01889 / 1
EV802517 / ubiquitin/ribosomal protein S27a fusion protein
[Branchiostoma belcheri tsingtaunese] / 46/52 (88%) / 1e-23 / AAL55470 / 1
EV802518 / ATPase F0 subunit 6 [Riftia pachyptila] / 143/172 (83%) / 8e-62 / AAU20757 / 5
EV802519 / mitochondrial ATP synthase alpha subunit precursor [Strongylocentrotus purpuratus] / 77/109 (70%) / 1e-37 / NP_999743 / 2
EV802520 / mitochondrial ATP synthase lipid binding protein precursor [Aedes aegypti] / 93/151 (61%) / 2e-24 / ABF18033 / 2
EV802521 / mitochondrial ATP synthase gamma- subunit [Graphocephala atropunctata] / 58/72 (80%) / 3e-25 / ABD98774 / 1
EV802522 / ATP synthase mitochondrial F1 complex assembly factor 1 [Gallus gallus] / 53/165 (32%) / 8e-22 / XP_422453 / 1
EV802523 / ATPase, H+ transporting, lysosomal, V0 subunit c [Homo sapiens] / 35/36 (97%) / 5e-10 / EAW85501 / 1
EV802524 / mitochondrial carrier protein
[Trypanosoma brucei] / 187/270 (69%) / 6e-102 / EAN78850 / 1
EV802525 / translocase of outer mitochondrial membrane 70 homolog A isoform 3 [Pan troglodytes] / 110/184 (59%) / 1e-61 / XP_526255 / 1
EV802530 / peroxiredoxin 6 [Arenicola marina] / 155/222 (69%) / 4e-88 / AAY96294 / 1
EV802531 / succinate dehydrogenase cytochrome B small subunit precursor
[Branchiostoma belcheri tsingtaunese] / 57/157 (36%) / 1e-14 / AAQ18144 / 2
EV802532 / succinate dehydrogenase complex,
subunit C precursor [Danio rerio] / 63/165 (38%) / 4e-26 / XP_685575 / 3
EV802533 / phospholipid hydroperoxide glutathione peroxidase A [Danio rerio] / 136/163 (83%) / 1e-77 / AAO86704 / 1
EV802534 / aldolase A isoform 1 [Macaca mulatta] / 250/251 (99%) / 2e-130 / XP_001107644 / 1
EV802535 / dopa decarboxylase protein
[Platynereis dumerilii] / 75/152 (49%) / 6e-37 / CAJ38793 / 1
EV802536 / sterol-C4-methyl oxidase-like protein
[Strongylocentrotus purpuratus] / 76/103 (73%) / 4e-43 / XP_787442 / 1
EV802537 / carbonic anhydrase [Anthopleura elegantissima] / 78/149 (52%) / 4e-34 / AAD32675 / 1
EV802538 / xylose isomerase [Oryza sativa] / 188/320 (58%) / 2e-109 / BAC83596 / 1
EV802539 / Acyl-CoA Synthetase [Sinorhizobium meliloti] / 32/67 (47%) / 6e-13 / NP_387435 / 1
EV802540 / ATP synthase [Ixodes scapularis] / 72/152 (47%) / 2e-33 / AAY66907 / 1
EV802541 / lysophosphatidylglycerol acyltransferase
[Danio rerio] / 148/332 (44%) / 1e-74 / AAH98616 / 1
EV802542 / glycine N-methyltransferase [Danio rerio] / 92/222 (41%) / 1e-35 / AAH62527 / 1
EV802543 / N-acylethanolamine-hydrolyzing acid amidase
[Gallus gallus] / 64/112 (57%) / 8e-23 / XP_420596 / 1
EV802544 / S-adenosylhomocysteine hydrolase
[Gallus gallus] / 208/258 (80%) / 6e-128 / XP_417331 / 1
EV802545 / pancreatic secretory proteinase inhibitor (PSTI type) / 40/61 (65%) / 4e-17 / P11706 / 1
EV802546 / transmembrane protease, serine 11B
[Homo sapiens] / 26/35 (74%) / 8e-10 / AAI26196 / 1
Cytoskeleton and Membrane Proteins
EV802547 / alpha-tubulin I [Bos taurus] / 66/66 (100%) / 9e-33 / XP_001251078 / 1
EV802548 / alpha-tubulin 3 [Ciona intestinalis] / 132/136 (97%) / 7e-74 / AAM73993 / 1
EV802549 / beta tubulin [Patella vulgata] / 94/96 (97%) / 4e-49 / CAA55979 / 1
EV802551 / tubulin cofactor a [Tribolium castaneum] / 39/62 (62%) / 2e-15 / XP_969241 / 1
EV802552 / nonmuscle myosin essential light chain
[Ixodes scapularis] / 102/147 (69%) / 3e-53 / AAY66877 / 1
EV802553 / Myosin regulatory light chain 2, smooth muscle isoform [Rattus norvegicus] / 144/171 (84%) / 5e-73 / XP_215905 / 1
EV802554 / tectorin alpha [Pan troglodytes] / 85/182 (46%) / 1e-35 / XP_508823 / 1
EV802555 / fascin [Aedes aegypti] / 54/124 (43%) / 6e-23 / EAT33922 / 1
EV802556 / Dnl2 protein [Danio rerio] / 85/92 (92%) / 5e-45 / AAI22095 / 1
EV802557 / Dynactin subunit 6 [Bos taurus] / 106/170 (62%) / 2e-54 / AAI18352 / 1
EV802558 / ankyrin repeat domain 5 [Danio rerio] / 96/203 (47%) / 3e-43 / CAH69033 / 1
EV802559 / exosomal core protein CSL4 [Bos taurus] / 108/188 (57%) / 4e-56 / AAX08988 / 1
EV802560 / Taxilin alpha [Strongylocentrotus purpuratus] / 199/336 (59%) / 1e-77 / XP_780699 / 1
EV802561 / Exocyst complex component 1 [Danio rerio] / 103/110 (93%) / 5e-54 / AAH54625 / 1
Replication, Transcription and Translation
EV802616 / translin-associated factor X [Xenopus tropicalis] / 116/260 (44%) / 1e-57 / AAH75580 / 1
EV802617 / Histone H2AV [Strongylocentrotuspurpuratus] / 103/103 (100%) / 1e-50 / XP_791430 / 1
EV802618 / H3 histone, family 3B [Mus musculus] / 136/136 (100%) / 4e-69 / XP_900402 / 1
EV802619 / branched chain aminotransferase 1, cytosolic [Xenopus tropicalis] / 45/69 (65%) / 9e-21 / AAH75501 / 1
EV802620 / lysyl-tRNA synthetase [Danio rerio] / 128/161 (79%) / 6e-71 / AAT68104 / 1
EV802621 / eukaryotic translation initiation factor 3, subunit 9 eta [Xenopus tropicalis] / 120/215 (55%) / 3e-69 / NP_001016724 / 2
EV802622 / elongation factor-1 alpha [Escarpia sp.] / 236/254 (92%) / 6e-134 / BAA25746 / 1
EV802624 / elongation factor 1 beta [Oryzias latipes] / 60/76 (78%) / 1e-28 / CAB40840 / 1
EV802625 / eukaryotic translation elongation factor 1 beta 2 [Xenopus tropicalis] / 112/188 (59%) / 2e-41 / AAH77005 / 1
EV802626 / elongation factor-1 gamma [Diguetia canites] / 59/72 (81%) / 3e-30 / ABG88953 / 3
EV802592 / SKIV2L2 [Strongylocentrotus purpuratus] / 65/78 (83%) / 2e-55 / XP_001197942 / 1
Ribosomal Proteins
EV802627 / ribosomal protein L21 [Argopecten irradians] / 20/35 (57%) / 4e-04 / AAN05604 / 1