Supplementary File 9

Table 4S. List of the UniESTs that reveal homology to secondary metabolism genes. The putative genes identified are grouped into the four main secondary metabolic pathways, as well as a group of P450s that might participate in the biosynthesis of the metabolites. The terpenoid pathway is separated in MEP (mono- and diterpenes) and MVA (sesquiterpenes) pathways according to the class of terpenes generated.

Cluster ID / No of ESTs / Description from nr hit (BlastX) / % identity / E-value
Terpenes (MEP pathway)
Contig 118 / 9 / 1-deoxyxylulose-5-phosphate synthase [Mentha x piperita] / 96 / 2E-51
Contig 175 / 3 / 1-deoxy-d-xylulose 5-phosphate reductoisomerase [Salvia miltiorrhiza] / 97 / 5E-49
Salviafruticosa_01_K20_T7 / 1 / 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase [Nicotiana langsdorffii x Nicotiana sanderae] / 69 / 6E-93
Salviafruticosa_06_A18_T7 / 1 / 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplast precursor (CMK) [Mentha x piperita] / 84 / 5E-17
Contig 1 / 2 / 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [Nicotiana langsdorffii x Nicotiana sanderae] / 89 / 3E-31
Contig 104 / 4 / 1-hydroxy-2-methyl-butenyl 4-diphosphate reductase [Catharanthus roseus] / 84 / 3E-90
Salviafruticosa_05_B01_T7 / 1 / Isopentenyl pyrophosphate isomerase IDI2 [Melaleuca alternifolia] / 87 / 2E-103
Salviafruticosa_01_J07_T7 / 1 / Geranyl diphosphate synthase small subunit [Mentha haplocalyx var. piperascens] / 71 / 4E-16
Contig 61 / 12 / Cineole synthase [Salvia fruticosa] / 99 / 0.0
Contig 60 / 2 / 4S-limonene synthase [Mentha spicata] / 73 / 2E-128
Salviafruticosa_02_M01_T7 / 1 / Limonene synthase [Rosmarinus officinalis] / 87 / 1E-62
Contig 92 / 4 / (+)-bornyl diphosphate synthase, chloroplast precursor (SBS) [Salvia officinalis] / 97 / 1E-114
Salviafruticosa_06_L11_T7 / 1 / (+)-bornyl diphosphate synthase, chloroplast precursor (SBS) [Salvia officinalis] / 73 / 4E-94
Contig 88 / 3 / Putative GGPP synthase [Eucommia ulmoides] / 82 / 9E-22
Contig 195 / 4 / Copalyldiphosphate synthase No1 [Lactuca sativa] / 38 / 2E-20
Contig 66 / 2 / ent-kaurene synthase-like protein 2 [Hordeum vulgare subsp. vulgare] / 31 / 6E-17
Terpenes (MVA pathway)
Salviafruticosa_01_G21_T7 / 1 / Acetoacetyl-CoA thiolase [Picrorhiza kurrooa] / 87 / 2E-139
Contig 189 / 2 / 3-hydroxy-3-methylglutaryl-CoA synthase [Nicotiana langsdorffii x Nicotiana sanderae] / 82 / 3E-28
Salviafruticosa_03_P13_T7 / 1 / 3-hydroxy-3-methylglutaryl-CoA reductase [Salvia miltiorrhiza] / 97 / 9E-107
Contig 40 / 3 / Farnesyl diphosphate synthase [Mentha x piperita] / 96 / 1E-157
Salviafruticosa_01_H10_T7 / 1 / Farnesyl diphosphate synthase [Mentha x piperita] / 67 / 7E-21
Contig 173 / 3 / Germacrene D synthase [Ocimum basilicum] / 59 / 2E-93
Contig 53 / 13 / Germacrene D synthase [Ocimum basilicum] / 53 / 1E-163
Contig 131 / 2 / cis-muuroladiene synthase [Mentha x piperita] / 68 / 3E-76
Phenylpropanoids
Contig 6 / 6 / Phenylcoumaran benzylic ether reductase homolog Fi1 [Forsythia x intermedia] / 70 / 2E-117
Contig 14 / 24 / Phenylcoumaran benzylic ether reductase homolog Fi1 [Forsythia x intermedia] / 73 / 8E-122
Salviafruticosa_03_G08_T7 / 1 / Caffeoyl-CoA O-methyltransferase [Plantago major] / 74 / 1E-07
Contig 180 / 10 / Caffeic acid 3-O-methyltransferase [Catharanthus roseus] / 64 / 1E-58
Salviafruticosa_04_E11_T7 / 1 / Caffeic acid 3-O-methyltransferase 2 [Ocimum basilicum] / 68 / 7E-49
Salviafruticosa_04_O24_T7 / 1 / Putative sinapyl alcohol dehydrogenase [Populus tremula x Populus tremuloides] / 73 / 6E-53
Flavonoids
Salviafruticosa_03_H05_T7 / 1 / Flavonoid 8-O-methyltransferase [Mentha x piperita] / 75 / 2E-14
Contig 148 / 2 / Flavonoid 4'-O-methyltransferase [Mentha x piperita] / 70 / 4E-08
Salviafruticosa_04_E11_T7 / 1 / Caffeic acid 3-O-methyltransferase 2 [Ocimum basilicum] / 68 / 7E-49
Salviafruticosa_05_K03_T7 / 1 / Anthocyanidin 3-O-glucosyltransferase 4 [Manihot esculenta] / 55 / 1E-13
Contig 144 / 3 / Chalcone-flavanone isomerase familyexpressed [Oryza sativa (japonica cultivar-group)] / 65 / 3E-55
Contig 180 / 10 / Caffeic acid 3-O-methyltransferase [Catharanthus roseus] / 64 / 1E-58
Alkaloids
Contig 105 / 3 / triose phosphate isomerase cytosolic isoform-like [Solanum tuberosum] / 85 / 3E-76
Salviafruticosa_04_N15_T7 / 1 / aspartate aminotransferase [Panicum miliaceum] / 88 / 3E-153
Contig 35 / 2 / GDSL-motif lipase/hydrolase family protein [Arabidopsis thaliana] / 65 / 1E-27
Salviafruticosa_03_H03_T7 / 1 / GDSL-motif lipase/hydrolase family protein [Arabidopsis thaliana] / 68 / 7E-107
Salviafruticosa_03_M01_T7 / 1 / GDSL-like Lipase/Acylhydrolase, putative [Oryza sativa (japonica cultivar-group)] / 63 / 1E-60
Salviafruticosa_04_E03_T7 / 1 / phospholipase/carboxylesterase family protein [Arabidopsis thaliana] / 66 / 7E-51
Salviafruticosa_04_J22_T7 / 1 / GDSL-motif lipase/acylhydrolase precursor [Phillyrea latifolia] / 80 / 2E-33
Cyt. P450
Contig 29 / 2 / NADPH--cytochrome P450 reductase (CPR) [Catharanthus roseus] / 72 / 2E-49
Contig 33 / 2 / Cytochrome P450 [Pyrus communis] / 58 / 1E-69
Contig 69 / 15 / Cytochrome P450 [Verbena x hybrida] / 49 / 5E-67
Contig 98 / 2 / Cytochrome P450 [Solanum tuberosum] / 59 / 7E-23
Salviafruticosa_02_P03_T7 / 1 / Putative cytochrome P450 [Oryza sativa (japonica cultivar-group)] / 61 / 2E-43
Salviafruticosa_03_H02_T7 / 1 / Cytochrome P450 [Ipomoea nil] / 68 / 1E-27
Salviafruticosa_03_H09_T7 / 1 / Cytochrome P450 monooxygenase CYP76E3 [Glycine max] / 54 / 2E-25
Salviafruticosa_05_D17_T7 / 1 / Putative cytochrome P450 monooxygenase CYP92A1[Oryza sativa (japonica cultivar-group)] / 54 / 4E-60
Salviafruticosa_06_A03_T7 / 1 / Putative ripening-related P-450 enzyme [Vitis vinifera] / 33 / 0.001