Supplemental Table 2Alignment of sequences used in analysis of Sox transcription factors ______
Alignment: C:\Users\Oscar\Documents\MiteTranscriptome454\Muscle\bilaterianaligment6.fasta
Seaview [blocks=10 fontsize=10 A4] on Sun Mar 13 13:54:40 2011
1
Xenopus_Sox13 MDTIQGELVY CPANEQECRI SAKIPISPSE DTGGPCLKVE EDYEEVSLQT
Xenopus_Sox7 ------
Xenopus_Sox9A ------
Xenopus_Sox11A ------
Xenopus_Sox2 ------
Xenopus_Sox14 ------
Strongylocentrotus_XM_781716.2 ------
Strongylocentrotus_NM_214473.1 ------
Strongylocentrotus_NM_214474.1 ------
Strongylocentrotus_XM_001176459.1 ------
Strongylocentrotus_XM_786890.2 ------
Strongylocentrotus_NM_214472.1 ------
Drosophila_Sox102F ------
MITE_454Assem.5595.C1 ------
Mus_musculus_SOX-13 ------
NvSOXD ------
AgSOXD ------
AgSOXC ------
NvSOXF ------
AmSOXF ------
DmSox14 ------
DmSox15 ------
MmSox7 ------
MmSox9 ------
AmSOXE2 ------
NvSOXE2 ------
GQ6VMKX01CVUP8 ------
TcSOXC ------
NvSOXC ------
AmSOXC ------
MmSox11 ------
Dm100B ------
AgSOXE ------
AgSOXdichaete ------
DmSoxDichaete ------
MmSox2 ------
DmSoxNeuro ------
AgSOXneuro ------
GQ6VMKX01ATTSG ------
AmSOXB1 ------
TcSOXB1 ------
MITE_454Assem.6107.C1 ------
DmSox21a ------
AmSOX21 ------
MmSox14 ------
AmSOXB2 ------
MITE_454Assem.sd.9120.C1 ------
NvSOX21b ------
NvSOXB2 ------
AmSOX21b ------
DmSox21b ------
AgSOX21b ------
TcSOXB2 ------
MITE_454Assem.9481.C1 ------
AgSOX21a ------
AgSOXF ------
Ixodes_XM_002405835.1 ------
Ixodes_XM_002415496.1 ------
Ixodes_XM_002404083.1 ------
Ixodes_XM_002404066.1 ------
Ixodes_XM_002434573.1 ------
Ixodes_XM_002409732.1 ------
Ixodes_XM_002416402.1 ------
Ixodes_XM_002415871.1 ------
51
Xenopus_Sox13 GIVPVFIKQD YESSSQDAND LCKPQGDAPA SDRKEENLKL SKTVSDAMPA
Xenopus_Sox7 ------
Xenopus_Sox9A ------
Xenopus_Sox11A ------
Xenopus_Sox2 ------
Xenopus_Sox14 ------
Strongylocentrotus_XM_781716.2 ------
Strongylocentrotus_NM_214473.1 ------
Strongylocentrotus_NM_214474.1 ------
Strongylocentrotus_XM_001176459.1 ------
Strongylocentrotus_XM_786890.2 ------
Strongylocentrotus_NM_214472.1 ------
Drosophila_Sox102F ------
MITE_454Assem.5595.C1 ------
Mus_musculus_SOX-13 ------
NvSOXD ------
AgSOXD ------
AgSOXC ------
NvSOXF ------
AmSOXF ------
DmSox14 ------
DmSox15 ------
MmSox7 ------
MmSox9 ------
AmSOXE2 ------
NvSOXE2 ------
GQ6VMKX01CVUP8 ------
TcSOXC ------
NvSOXC ------
AmSOXC ------
MmSox11 ------
Dm100B ------
AgSOXE ------
AgSOXdichaete ------
DmSoxDichaete ------
MmSox2 ------
DmSoxNeuro ------
AgSOXneuro ------
GQ6VMKX01ATTSG ------
AmSOXB1 ------
TcSOXB1 ------
MITE_454Assem.6107.C1 ------
DmSox21a ------
AmSOX21 ------
MmSox14 ------
AmSOXB2 ------
MITE_454Assem.sd.9120.C1 ------
NvSOX21b ------
NvSOXB2 ------
AmSOX21b ------
DmSox21b ------
AgSOX21b ------
TcSOXB2 ------
MITE_454Assem.9481.C1 ------
AgSOX21a ------
AgSOXF ------
Ixodes_XM_002405835.1 ------
Ixodes_XM_002415496.1 ------
Ixodes_XM_002404083.1 ------
Ixodes_XM_002404066.1 ------
Ixodes_XM_002434573.1 ------
Ixodes_XM_002409732.1 ------
Ixodes_XM_002416402.1 ------
Ixodes_XM_002415871.1 ------
101
Xenopus_Sox13 LEKFLSNDWK EILLGNSTVG SKDFKGTKES LAEKELQLLL MIHQLTGLRD
Xenopus_Sox7 ------
Xenopus_Sox9A ------
Xenopus_Sox11A ------
Xenopus_Sox2 ------
Xenopus_Sox14 ------
Strongylocentrotus_XM_781716.2 ------
Strongylocentrotus_NM_214473.1 ------
Strongylocentrotus_NM_214474.1 ------
Strongylocentrotus_XM_001176459.1 ------
Strongylocentrotus_XM_786890.2 ------
Strongylocentrotus_NM_214472.1 ------
Drosophila_Sox102F ------AAAAVAAA
MITE_454Assem.5595.C1 ------
Mus_musculus_SOX-13 ------V MIHQLSALRD
NvSOXD ------
AgSOXD ------GP AGLFAGCDTD
AgSOXC ------
NvSOXF ------CQRYHHA AGSSVPTPPP
AmSOXF ------
DmSox14 ------
DmSox15 ------MEPSYDH
MmSox7 ------
MmSox9 ------
AmSOXE2 ------
NvSOXE2 ------
GQ6VMKX01CVUP8 ------
TcSOXC ------
NvSOXC ------
AmSOXC ------
MmSox11 ------
Dm100B ------
AgSOXE ------
AgSOXdichaete ------
DmSoxDichaete ------
MmSox2 ------
DmSoxNeuro ------
AgSOXneuro ------
GQ6VMKX01ATTSG ------
AmSOXB1 ------
TcSOXB1 ------
MITE_454Assem.6107.C1 ------
DmSox21a ------
AmSOX21 ------
MmSox14 ------
AmSOXB2 ------
MITE_454Assem.sd.9120.C1 ------
NvSOX21b ------
NvSOXB2 ------
AmSOX21b ------
DmSox21b ------LS
AgSOX21b ------
TcSOXB2 ------
MITE_454Assem.9481.C1 ------
AgSOX21a ------
AgSOXF ------
Ixodes_XM_002405835.1 ------
Ixodes_XM_002415496.1 ------MKN
Ixodes_XM_002404083.1 ------
Ixodes_XM_002404066.1 ------
Ixodes_XM_002434573.1 ------
Ixodes_XM_002409732.1 ------
Ixodes_XM_002416402.1 ------
Ixodes_XM_002415871.1 ------
151
Xenopus_Sox13 QLLSAHSEHR NLAAMLFEKQ QQQMDLARQQ QEQIAKQQQQ LIQQQHKINM
Xenopus_Sox7 ------
Xenopus_Sox9A ------MNL
Xenopus_Sox11A ------
Xenopus_Sox2 ------
Xenopus_Sox14 ------
Strongylocentrotus_XM_781716.2 ------HIL
Strongylocentrotus_NM_214473.1 ------
Strongylocentrotus_NM_214474.1 ------FSSF ISKRLTKMSV
Strongylocentrotus_XM_001176459.1 ------YF DAPVYTTKVN
Strongylocentrotus_XM_786890.2 ------
Strongylocentrotus_NM_214472.1 ------
Drosophila_Sox102F NNNKNSSHFS NNTNIVGLAT RGNELLNTDS DPQMEIGETR RGGNGGSCRS
MITE_454Assem.5595.C1 ------
Mus_musculus_SOX-13 QLLTAHSEQK NMAAMLFEKQ QQQMELARQQ QEQIAKQQQQ LIQQQHKINL
NvSOXD ------SS SSSSSSSSRN SPSLPPRRNS SPPACPCPGT TCPVCHTPGC
AgSOXD ELNHRLELMS DKVGLLPPTA VALLEKESDK YFLKSKRDRL ELDPNHLFDY
AgSOXC ------
NvSOXF APSNSSSSSS SNNNASNANN SASTSQQQQQ QQQASSPARE QAQTPGSIVQ
AmSOXF ------MCQ RYHHAVPAAQ NSSPARDPSA AIVQGLSTAT
DmSox14 ------MIAKPNQAT TEPPLSLRPG TVPTVPATTP ARPATITIQR
DmSox15 EHPHHLLTNY NSKKYPHVSR TPEYSHSTGS DYPEHGGYLT DGRLMHESNS
MmSox7 ------
MmSox9 ------MNL
AmSOXE2 ------MESYHHG
NvSOXE2 ------
GQ6VMKX01CVUP8 ------
TcSOXC ------
NvSOXC ------
AmSOXC ------
MmSox11 ------
Dm100B ------MSDSSSSN CSKDRAKPVE
AgSOXE ------
AgSOXdichaete ------MI NHHTMASLGH
DmSoxDichaete ------MATLSTHPNY GFHLGQAQGL
MmSox2 ------
DmSoxNeuro -----MESDM KGSLLHATMP PHHTSAALHG HAASPYSALA PLMNLGQSHL
AgSOXneuro ------
GQ6VMKX01ATTSG ------
AmSOXB1 ------MLTM ETDLKGGSLH GQMPPHQGVS
TcSOXB1 ------MLTME TDLKGGSLHA
MITE_454Assem.6107.C1 ------
DmSox21a ------MTS ISALLHRSHS
AmSOX21 ------
MmSox14 ------
AmSOXB2 ------
MITE_454Assem.sd.9120.C1 ------
NvSOX21b ------
NvSOXB2 ------
AmSOX21b ------
DmSox21b LTGLSLAHPL QTHLGSGGGT HHLGQLAAAV HQQQQQQQQS DQGLGHSHHL
AgSOX21b ------
TcSOXB2 ------
MITE_454Assem.9481.C1 ------
AgSOX21a ------
AgSOXF ------
Ixodes_XM_002405835.1 ------
Ixodes_XM_002415496.1 ESFNEPILGA ERKLFAGSSA FSSDSGGRVR QRRVWGAAEA SLRAGPALRS
Ixodes_XM_002404083.1 ------MPSTPRR GGFPDDSFFP
Ixodes_XM_002404066.1 ------
Ixodes_XM_002434573.1 ------
Ixodes_XM_002409732.1 ------
Ixodes_XM_002416402.1 ------
Ixodes_XM_002415871.1 ------MTQ LEQEGLANQH QQEELRRQQE QLLEQQQKLH DLQARLSGQY
201
Xenopus_Sox13 LQQQIQQVNM PYVMIPAFPS AQTVSAEPQM SLPIQPIPCK PVEYPMPLLH
Xenopus_Sox7 ------MTTLMGSY SWTESLDCSP M------
Xenopus_Sox9A LDPFMKMTEE QDKCMSGAPS PTMSDDSAGS P------
Xenopus_Sox11A ------MVQR ADMDSSQHTE PSTDTEEGEF M------
Xenopus_Sox2 ------MYSMMETELK PPAPQQPSGG N------
Xenopus_Sox14 ------
Strongylocentrotus_XM_781716.2 NNMSSPESLE LHHSLSEGSS PRTPGSDSDD A------
Strongylocentrotus_NM_214473.1 ------KP ASDFMMMDSA M------
Strongylocentrotus_NM_214474.1 PGVHEQPELK HSVNVMASSI PGMAHHVGVT Q------
Strongylocentrotus_XM_001176459.1 ADFKMVPQNL TSNGLITMQS QQIPNGHGSP G------
Strongylocentrotus_XM_786890.2 ------MRT VSELLRNDPK SGYPLATANA L------
Strongylocentrotus_NM_214472.1 YAHQLPIRSF SASDITMGNI SGSDDEDMLS R------
Drosophila_Sox102F RPESPTYENP PYEILSYSHN TPPESPHGRT A------DCSKNF
MITE_454Assem.5595.C1 ------
Mus_musculus_SOX-13 LQQQIQQVNM PYVMIPAFPP SHQPLPVTPD SQLALPIQPI PCKPVEYPLQ
NvSOXD RHTSARCPRL VMGKMPKEEN SGREAGGGSA P------
AgSOXD PGPSPDGLHK HAKLNLYHQS PSPHHGSPDD S------
AgSOXC ------
NvSOXF HIDQPSPSYS HYTMLDSYER GEVTPPPVSS Y------
AmSOXF HIDQASPSYS HYTMLDNYDR GEVTPPPVSS Y------
DmSox14 RHPAPKADST PHTLPPFSPS PSPASSPSPA P------
DmSox15 DAGIYHVRQG SEHSSPSLHS PAIQSSGYEN E------
MmSox7 ------MASLLGAY PWTEGLECPA L------
MmSox9 LDPFMKMTDE QEKGLSGAPS PTMSEDSAGS P------
AmSOXE2 NDVSGTAETE AGPSSAEQCS NEQCANSLDD A------
NvSOXE2 ------METNKAKAA TVREPSSLDD A------
GQ6VMKX01CVUP8 ------VP PVVPRRPSLA A------
TcSOXC ------M VPQQNMDSSR SETPISSAVP K------
NvSOXC ------MVPQQ QDSPSSSGIP L------
AmSOXC ------MVP QQQDSPSRGI F------
MmSox11 ----MVQQAE SSEAESNLPR DALDTEEGEF M------
Dm100B TLVLANYALK AEQKKAQGQG GRKEDERITT A------
AgSOXE ------MKDK WSEPQNILSP S------
AgSOXdichaete PHYGFALSNG MDIPPAADFA PQPHHSPNSP T------
DmSoxDichaete EDYAPQSQLQ LSPGMDMDIK RVLHYSQSLA A------
MmSox2 ------MYNMMETELK PPGPQQASGG G------
DmSoxNeuro THSQLSHHNH HHHHMSAHIA ASQSPNPLSS L------
AgSOXneuro ------
GQ6VMKX01ATTSG ------
AmSOXB1 PMGHHTGVSP YGSLGSIVHS PALSGSPPST G------
TcSOXB1 TMPPHHAIQS YGSLAPMHMG QHPHQMHHQP Q------
MITE_454Assem.6107.C1 ------
DmSox21a HSNGYTSSGS SNHSHSSSLS PQLPGINLGL G------
AmSOX21 ------MLNSHQQH PGYGFLSGMD L------
MmSox14 ------
AmSOXB2 ------MSS K------
MITE_454Assem.sd.9120.C1 ------
NvSOX21b ------MCDGSFQETL RGMQGMSGAS P------
NvSOXB2 ------MSS K------
AmSOX21b ----MRAGGN MCDGSFTETL RGMQGMPGTS P------
DmSox21b HGQQLSLNHQ HHHPHQSPQH QQQHQHHPCS SNSSNGSPNG STGLGLHPHS
AgSOX21b ------ML K------
TcSOXB2 ------MSSPKP I------
MITE_454Assem.9481.C1 ------
AgSOX21a ------MD MTMASKNHSP ------
AgSOXF ------WGGYALTAA GPYQSEFCAS N------
Ixodes_XM_002405835.1 ------MNQQQQGGG R------
Ixodes_XM_002415496.1 EEAASNGGLA SAIGPAGEPL RSSPSDRVNR PASVESAVLV KPRTGVCPSL
Ixodes_XM_002404083.1 KKVIELVTME PSGSRRNRQQ SAVEPGPVFD D------
Ixodes_XM_002404066.1 ------
Ixodes_XM_002434573.1 ------M GWRCPFWTAD QWATWARGRP S------
Ixodes_XM_002409732.1 ------MLL PHQTVIHKGP PALASPPHAE V------
Ixodes_XM_002416402.1 ------MVPHTSSLHP DTMEQKPRGQ Q------
Ixodes_XM_002415871.1 LAAASVSKGF LLMPMLEATL PRVPARPVSS PTAAHTPPTA AMSPLQPWVS
251
Xenopus_Sox13 NSHAGRGSAS AKHQETSQPL NLTAKPKCPD QFPNSSSSPE FRMSPVGSQC
Xenopus_Sox7 ------DGDLS DGLSPHRSPR E------
Xenopus_Sox9A ------CPSGS GSDTENTRPQ ENTFPKGDQE
Xenopus_Sox11A ------ACSP VPLDESDPDW C------
Xenopus_Sox2 ------SNSAS NNQN------
Xenopus_Sox14 ------
Strongylocentrotus_XM_781716.2 ------SSECS REDLAILSSR VDPSSLVVGP
Strongylocentrotus_NM_214473.1 ------
Strongylocentrotus_NM_214474.1 ------ASVMG NGPAGMGGNK NNSNP-----
Strongylocentrotus_XM_001176459.1 ------STGSS EELRQSTLDI AEDICQTNWStrongylocentrotus_
XM_786890.2 ------QSALL ASNGTLIAGT ALSGGMGVWS
Strongylocentrotus_NM_214472.1 ------KGIVI DLTEEDERPK IDIQVDHAGT
Drosophila_Sox102F SPSPTDNLSI ASVSEAQDSE MDAPLNLSKP KGSPSSSPNS SSQRDHCENL
MITE_454Assem.5595.C1 ------
Mus_musculus_SOX-13 LLHSPPAPVV KRSGVAAHHP LQEP-PQPLN LTAKPKVPEL PNTSSSPSLK
NvSOXD ------SGSAT AAAVAAVEKH FAMHGIYGMP
AgSOXD ------KQGGG LGGLGESPYP LAQQFFIKAA
AgSOXC ------
NvSOXF ------AGSPGLLA LHSSLYGTPT SRAFDIDSGI
AmSOXF ------GGSPGLLA LHSSLYATPT SRAYDIESNI
DmSox14 --AQTPGAQK TQSQAAITHP AAVASPSAPV AAAAPKTPKT PEPRSTHTHT
DmSox15 ----HLNEAV LAAHSHSHSP MPMVSSAYVG GGTASGSLIN SNIPLLGGGG
MmSox7 ------EAELS DGLSPPAVPR PSGD------
MmSox9 ------CPSGS GSDTENTRPQ ENTFPKGEPD
AmSOXE2 ------VGKLL QGYDWTLLPV TSRAG-----
NvSOXE2 ------VGKLL QGYDWTLLPV TSRAG-----
GQ6VMKX01CVUP8 ------
TcSOXC ------FGSQL IDKNSATPYS DATQTK----
NvSOXC ------FGSLL VDKNSSTPYS DATQTK----
AmSOXC ------FQSVS PFLFQTK------
MmSox11 ------ACSP VALDESDPDW C------
Dm100B ------VMKVL EGYDWNLVQA SAKAPT----
AgSOXE ------
AgSOXdichaete ------DHLGLK RGLTFPASSL ASLQGMGGGG
DmSoxDichaete ------MGGSP NGPAGQGVNG SSGMGHHMSS
MmSox2 ------GGGGN ATAAATGGNQ ------
DmSoxNeuro ------QSSMA NTLNGSQVGQ QQQQQQQQQS
AgSOXneuro ------TGGLL GVNHNNNNTS KAA------
GQ6VMKX01ATTSG ------
AmSOXB1 ------G LGLGLPHHHQ TPQHHYASMQ AAQQQQQQQQ
TcSOXB1 ------PPQPP PQLHHHQPPS TQHQTQNNNN
MITE_454Assem.6107.C1 ------
DmSox21a ------MVGGLG MGMSVGVGSG SGNTTPPPMP
AmSOX21 ------HTVHH VGQDMNVANQ PIA------
MmSox14 ------
AmSOXB2 ------
MITE_454Assem.sd.9120.C1 ------
NvSOX21b ------PGGAA VGPMVGAVGL TSPLGSASAA
NvSOXB2 ------
AmSOX21b ------PGGAG VGPMGVGLGS PLGPSPK---
DmSox21b ALHLAHHHSQ LHQHHPAGQQ QQHSQPPVSS SSTSHHSQSQ ALSHQTHSNG
AgSOX21b ------
TcSOXB2 ------
MITE_454Assem.9481.C1 ------
AgSOX21a ------
AgSOXF ------YGVLH QRQAYGGPHG AGKLGPHGGL
Ixodes_XM_002405835.1 ------
Ixodes_XM_002415496.1 AVASTSTSAW PRAAWQHDAA ELRPSPAACP CQLCSSGADH RQQASPAALA
Ixodes_XM_002404083.1 ------DSCSG DGSDSGTDPL ENNPGIQAAV
Ixodes_XM_002404066.1 ------PACC------
Ixodes_XM_002434573.1 ------PSSPS NGPSSLRPTI SSSS------
Ixodes_XM_002409732.1 ------PVSMS ------
Ixodes_XM_002416402.1 ------FGSLK VDVNSPTPYT DATQC-----
Ixodes_XM_002415871.1 GAGPLLPLSG SPLTPTVRLG PGGPSPASVG SGNRTPTPST APDPAPDSDT
301
Xenopus_Sox13 GGTMDSASSS QKANLPLGFL GEGDAITKAI QEACQLLHGQ NTSPEHCQQN
Xenopus_Sox7 ------
Xenopus_Sox9A LKKETEDEKF P------VCIR EAVSQVLKGY DWTLVPMPVR
Xenopus_Sox11A ------
Xenopus_Sox2 ------
Xenopus_Sox14 ------
Strongylocentrotus_XM_781716.2 EGTAAQFS------PSIR DAVSRVLNGY DWSVVAIPSR
Strongylocentrotus_NM_214473.1 ------
Strongylocentrotus_NM_214474.1 ------
Strongylocentrotus_XM_001176459.1 ------
Strongylocentrotus_XM_786890.2 EAVVGQRVLD NGGGLR------
Strongylocentrotus_NM_214472.1 IARMYRDSRK A------
Drosophila_Sox102F TPVVSSPPLS WHQGQPHYAE IELPLLKSHG RVWNSAVACS GGSRATRVSR
MITE_454Assem.5595.C1 ------
Mus_musculus_SOX-13 MNSCGPRPAS HGAPTRDLQS SPPSLPLGFL GEGDAVTKAI QDARQLLHSH
NvSOXD PPSTGAMPPS PQQQRQIKHS SARDEPPPED DFLSLHVWRD SGYKVTEDIA
AgSOXD DGGPGGPGLS PFNSNAMLDN MNRHLIQRQQ TMAAVSGSGK KDKGLSLGGL
AgSOXC ------
NvSOXF DGNESPMSMD TQIIPIPGML SGPTQQRLED MSWLGSGPSL QDYQQGLGPM
AmSOXF DGNDSSMPID TQIISIPGML SGPAQQRLED MSWLASGPSL EYQQGISPIP
DmSox14 HTHSQHFSPP PRESEMDGER SPSHSGHEMT LSMDGIDSSL VFGSARVPVN
DmSox15 NSVLNKFLSH PHAGMVGGGT GQMEDCTSHS PIEAASMWSY DYKGDLCAPN
MmSox7 ------
MmSox9 LKKESEEDKF P------VCIR EAVSQVLKGY DWTLVPMPVR
AmSOXE2 ------
NvSOXE2 ------
GQ6VMKX01CVUP8 ------
TcSOXC ------
NvSOXC ------
AmSOXC ------
MmSox11 ------
Dm100B ------
AgSOXE ------
AgSOXdichaete GGGVNGQTS------
DmSoxDichaete HMTPHHMHQA VSAQQTLSPN SSIGSAGSLG SQSSLGSNGS GLNSSSGHQS
MmSox2 ------
DmSoxNeuro SPLHSSSELS PTQSSIGSHH MTSPVSHQQH TQQQQHGQQQ HLGAGSALSS
AgSOXneuro ------
GQ6VMKX01ATTSG ------
AmSOXB1 QQTIHSLAQQ NAGQQQQQHQ HHPHQPPQQQ SQTSHHQSAN NNNNTSKNNN
TcSOXB1 NNTK------
MITE_454Assem.6107.C1 ------
DmSox21a PADLAVPPAA PTPVAPKMHQ HTHHHGNSHH NAPTSHSNSN TGSH------
AmSOX21 ------
MmSox14 ------
AmSOXB2 ------
MITE_454Assem.sd.9120.C1 ------
NvSOX21b K------
NvSOXB2 ------
AmSOX21b ------
DmSox21b SSQLGGGSAS GAGSVAGGAA NSHHSAPASS SVMAAAAAAH LHHNSQASPI
AgSOX21b ------
TcSOXB2 ------
MITE_454Assem.9481.C1 ------
AgSOX21a ------
AgSOXF K------
Ixodes_XM_002405835.1 ------
Ixodes_XM_002415496.1 SLEREYAAAF PYGGPPPHQP VEDIKPVVSS SPPQQLGPTS LVGHHGGGPH
Ixodes_XM_002404083.1 SKVLQSYDWS LVAKTTRQGG S------
Ixodes_XM_002404066.1 ------
Ixodes_XM_002434573.1 ------
Ixodes_XM_002409732.1 ------
Ixodes_XM_002416402.1 ------
Ixodes_XM_002415871.1 PLNLSKPRGS SSGSTASSDA MHLHSAARFQ NSAEISVSGA LELIDLYLCS
351
Xenopus_Sox13 YRKELLDTLP EKNIQDVTSL HHTEASLLRC SMDID------
Xenopus_Sox7 ------
Xenopus_Sox9A VNGS------
Xenopus_Sox11A ------
Xenopus_Sox2 ------
Xenopus_Sox14 ------
Strongylocentrotus_XM_781716.2 TGPN------
Strongylocentrotus_NM_214473.1 ------
Strongylocentrotus_NM_214474.1 ------
Strongylocentrotus_XM_001176459.1 ------
Strongylocentrotus_XM_786890.2 ------
Strongylocentrotus_NM_214472.1 ------
Drosophila_Sox102F DSVNSCGTNS ERSAALDPES LNSGQLGPVP ASPSSQPLRQ GNGHGHGGNH
MITE_454Assem.5595.C1 ------
Mus_musculus_SOX-13 SGALENSPNT PFRKDLISLD SSPAKERLEE SCVHPLEEAM LSCDMDGSRH
NvSOXD EKAKMVRQQK RE------
AgSOXD DLGPDLGTGR SRSS------
AgSOXC ------
NvSOXF SAGVKMCHPG SGSAAAR------
AmSOXF AGVKMCHPGS TAQR------
DmSox14 SSTPYSDATR TK------
DmSox15 CGYLERHKPL PADLKYRPGG TQSK------
MmSox7 ------
MmSox9 VNGS------
AmSOXE2 ------
NvSOXE2 ------
GQ6VMKX01CVUP8 ------
TcSOXC ------
NvSOXC ------
AmSOXC ------
MmSox11 ------
Dm100B ------
AgSOXE ------
AgSOXdichaete ------
DmSoxDichaete AGMHSLATS------
MmSox2 ------
DmSoxNeuro LTGGSSNNNN NSATANKN------
AgSOXneuro ------
GQ6VMKX01ATTSG ------
AmSOXB1 IDRSQTSHHL SANNNNNTSK ------
TcSOXB1 ------
MITE_454Assem.6107.C1 ------
DmSox21a ------
AmSOX21 ------
MmSox14 ------
AmSOXB2 ------
MITE_454Assem.sd.9120.C1 ------
NvSOX21b ------
NvSOXB2 ------
AmSOX21b ------
DmSox21b SNLHQNMGSL MNSGSSASDV FFSLMIQNTT K------
AgSOX21b ------
TcSOXB2 ------
MITE_454Assem.9481.C1 ------
AgSOX21a ------
AgSOXF ------
Ixodes_XM_002405835.1 ------
Ixodes_XM_002415496.1 GAQHPGQAGG GHGGHGGGS------
Ixodes_XM_002404083.1 ------
Ixodes_XM_002404066.1 ------
Ixodes_XM_002434573.1 ------
Ixodes_XM_002409732.1 ------
Ixodes_XM_002416402.1 ------
Ixodes_XM_002415871.1 TLVEQEGKVF AQKTEVSIGK IAGAKIIRQT KKD------
401
Xenopus_Sox13 ---GSRGNHI KRPMNAFMVW AKDERRKILQ AFPDMHNSSI SKILGSRWKS
Xenopus_Sox7 ---KGSETRI RRPMNAFMVW AKDERKRLAV QNPDLHNAEL SKMLGKSWKA
Xenopus_Sox9A ---SKNKPHV KRPMNAFMVW AQAARRKLAD QYPHLHNAEL SKTLGKLWRL
Xenopus_Sox11A ---KTATGHI KRPMNAFMVW SKIERRKIME QSPDMHNAEI SKRLGKRWKM
Xenopus_Sox2 ---KNSPDRV KRPMNAFMVW SRGQRRKMAQ ENPKMHNSEI SKRLGAEWKL
Xenopus_Sox14 --MSKPVDHI KRPMNAFMVW SRGQRRKMAQ ENPKMHNSEI SKRLGAEWKL
Strongylocentrotus_XM_781716.2 ---GKRKPHI KRPMNAFMVW AQAARKKLGN QYPQLHNAEL SKTLGKLWRL
Strongylocentrotus_NM_214473.1 ---GKGTDHV KRPMNAFMVW SRGQRRKLAQ ENPKMHNSEI SKRLGAEWKL
Strongylocentrotus_NM_214474.1 ---NNNPDRV KRPMNAFMVW SRGQRRKLSQ ENPKMHNSEI SKRLGAEWKL
Strongylocentrotus_XM_001176459.1 ---KGNNGHI KRPMNAFMVW SQIERRRIME TTPDMHNAEI SKRLGRRWKT
Strongylocentrotus_XM_786890.2 ---GRKEARI RRPMNAFMVW AKDERKRLAD QNPDLHNADL SKLLGKAWRS
Strongylocentrotus_NM_214472.1 ---EASKPHI KRPMNAFMVW AKEERRKILA RHPDMHNSNI SKILGSKWKT
Drosophila_Sox102F GH-VHSKPHI KRPMNAFMVW AKDERRKILK ACPDMHNSNI SKILGARWKA
MITE_454Assem.5595.C1 ------TWRMus_
musculus_SOX-13 FSESRNSSHI KRPMNAFMVW AKDERRKILQ AFPDMHNSSI SKILGSRWKS
NvSOXD ---GENKPHI KRPMNAFMVW AKDERRKILK ACPDMHNSNI SKILGARWKD
AgSOXD ---STEKNHI KRPMNAFMVW AKDERRKILK ACPDMHNSNI SKILGARWKA
AgSOXC ------MNPFMVW SQIERRKICE VTPDMHNAVI SKNLGQRWKQ
NvSOXF ---SLKEQRI RRPMNAFMVW AKVERKKLAD ENPDLHNADL SKMLGKKWRG
AmSOXF ---SLKEQRI RRPMNAFMVW AKVERKKLAD ENPDLHNADL SKMLGKKWRG
DmSox14 ---KHSPGHI KRPMNAFMVW SQMERRKICE RTPDLHNAEI SKELGRRWQL
DmSox15 ---SAKESRI RRPMNAFMVW AKIERKKLAD ENPDLHNADL SKMLGKKWRS
MmSox7 ---KSSESRI RRPMNAFMVW AKDERKRLAV QNPDLHNAEL SKMLGKSWKA
MmSox9 ---SKNKPHV KRPMNAFMVW AQAARRKLAD QYPHLHNAEL SKTLGKLWRL
AmSOXE2 ---GRRSAHV KRPMNAFMVW AQAARRRLAD QYPQLHNAEL SKTLGKLWRI
NvSOXE2 ---GRRSAHV KRPMNAFMVW AQAARRRLAD QYPQLHNAEL SKTLGKLWRI
GQ6VMKX01CVUP8 ---QKKRLHI KRPMNAFMVW AQAARRKLSD HHKNLHNAEL SKTLGKLWKTcSOXC
---KNNPNHI KRPMNAFMVW SQIERRKICE VQPDMHNAEI SKKLGRRWKE
NvSOXC ---KNNPNHI KRPMNAFMVW SQIERRKICS IQPDMHNAEI SKRLGRRWKT
AmSOXC ---KNNPNHI KRPMNAFMVW SQIERRKICE IQPDMHNAEI SKRLGRRWKT
MmSox11 ---KTASGHI KRPMNAFMVW SKIERRKIME QSPDMHNAEI SKRLGKRWKM
Dm100B ---DRKKEHI KRPMNAFMVW AQAARRVMSK QYPHLQNSEL SKSLGKLWKN
AgSOXE ---TKKKQHI KRPMNAFMVW AQAARREMAQ QQPRLQNSEI SKDLGKIWKAgSOXdichaete
---PGQEGHI KRPMNAFMVW SRLQRRQIAK DNPKMHNSEI SKRLGSEWKL
DmSoxDichaete ---PGQEGHI KRPMNAFMVW SRLQRRQIAK DNPKMHNSEI SKRLGAEWKL
MmSox2 ---KNSPDRV KRPMNAFMVW SRGQRRKMAQ ENPKMHNSEI SKRLGAEWKL
DmSoxNeuro ---QQHADRV KRPMNAFMVW SRGQRRKMAS DNPKMHNSEI SKRLGAQWKD
AgSOXneuro ---QQNADRV KRPMNAFMVW SRGQRRKMAS DNPKMHNSEI SKRLGAQWKD
GQ6VMKX01ATTSG ---GLVPS------GRYYSAmSOXB1
---NNNIDRV KRPMNAFMVW SRGQRRKMAQ ENPKMHNSEI SKRLGAEWKL
TcSOXB1 ---SQNMERV KRPMNAFMVW SRGQRRKMAQ ENPKMHNSEI SKRLGAEWKL
MITE_454Assem.6107.C1 ------IAL ENPKMHNSEI SRRLGGEWKA
DmSox21a ---HNSHDHI KRPMNAFMVW SRGQRRKMAQ DNPKMHNSEI SKRLGAEWKL
AmSOX21 ---ASQEQHI KRPMNAFMVW SRIQRKKIAL ENPKMHNSEI SKRLGAEWKL
MmSox14 --MSKPSDHI KRPMNAFMVW SRGQRRKMAQ ENPKMHNSEI SKRLGAEWKL
AmSOXB2 ---TLHNEHI KRPMNAFMVW SRGQRRKMAQ ENPKMHNSEI SKRLGAEWKL
MITE_454Assem.sd.9120.C1 ------
NvSOX21b ---RMQADHI KRPMNAFMVW SRSQRKKIAH DNPKMHNSEI SKRLGAEWKL
NvSOXB2 ---TLHNEHI KRPMNAFMVW SRGQRRKMAQ ENPKMHNSEI SKRLGAEWKL
AmSOX21b ---KAQVEHI KRPMNAFMVW SRLQRRKIAQ ENPKMHNSEI SKRLGAEWKL
DmSox21b ---RQNEEHI KRPMNAFMVW SRLQRRKIAQ DNPKMHNSEI SKRLGAEWKL
AgSOX21b ---KPAEEHI KRPMNAFMVW SRLQRRKIAQ DNPKMHNSEI SKRLGAEWKL
TcSOXB2 ---HHGQEHI KRPMNAFMVW SRGQRRKMAQ ENPKMHNSEI SKRLGAEWKL
MITE_454Assem.9481.C1 ------
AgSOX21a ---ASAGEHI KRPMNAFMVW SRGQRRKMAQ DNPKMHNSEI SKNLGAQWKL
AgSOXF ---SAKEARI RRPMNAFMVW AKVERKKLAD ENPDLHNADL SKMLGKSQ--
Ixodes_XM_002405835.1 ---TPGVEHI KRPMNAFMVW SRAQRRKIAL EHPKMHNSEI SKRLGAEWKQ
Ixodes_XM_002415496.1 ---KKDLDRV KRPMNAFMVW SRGQRRKMAQ ENPKMHNSEI SKRLGAEWKL
Ixodes_XM_002404083.1 ---EKKRLHV KRPMNAFMVW AQAARRKLAD QYPHLHNAEL SKTLGKLWRIxodes_
XM_002404066.1 -----TDSHI KRPLNAFMLW SRLQRRRFVH ANPGMQHPEV SKLLGVMWRQ
Ixodes_XM_002434573.1 ---SPTDSHV KRPMNAFMVW SRAQRRKIAL ENPKMHNSEI SKRLGTEWKH
Ixodes_XM_002409732.1 ---RGSPDHI KRPMNAFMVW SRGQRRKMAV ENPKMHNSEI SKRLGAEWKQ
Ixodes_XM_002416402.1 ---KKVTNHI KRPMNAFMVW SQIERRKICE QQPDMHNAEI SKRLGLRWKM
Ixodes_XM_002415871.1 ---PDGKPHI KRPMNAFMVW AKDERRKILK ACPDMHNSNI SKILGARWKA
451
Xenopus_Sox13 MSNGEKQPYY EEQARLSRQH LERYPDYKYK PRPK------RTCI
Xenopus_Sox7 LSPAQKRPYV EEAERLRVQH MQDYPNYKYR PRRK------KQIXenopus_
Sox9A LNEGEKRPFV EEAERLRVQH KKDHPDYKYQ PRRR------KSVK
Xenopus_Sox11A LNDSEKIPFI REAERLRLKH MADYPDYKYR PRKK------PKVXenopus_
Sox2 LSEAEKRPFI DEAKRLRALH MKEHPDYKYR PRRK------TKTXenopus_
Sox14 LSEAEKRPYI DEAKRLRAQH MKEHPDYKYR PRRK------PKNStrongylocentrotus_
XM_781716.2 LSDKEKQPFI EEAERLRQQH KKDYPDYKYQ PRRR------NKNStrongylocentrotus_
NM_214473.1 LSEDDKRPFI DEAKRLRALH MKEHPDYKYR PRRK------PKSStrongylocentrotus_
NM_214474.1 LSEDEKRPFI DEAKRLRAVH MKEHPDYKYR PRRK------TKTStrongylocentrotus_
XM_001176459.1 LDEVAKSPYV EEAERLRLLH MAQYPDYKYR PRKK------SKPStrongylocentrotus_
XM_786890.2 LTLMQKQPFV EEAERLRLKH MADHPDYKYR PRRR------KGKStrongylocentrotus_
NM_214472.1 MSNAEKQPYY EEQARLDKAH LEKYPDYKYK PRPK------RTCI
Drosophila_Sox102F MSNADKQPYY EEQSRLSKLH MEQHPDYRYR PRPK------RTCI
MITE_454Assem.5595.C1 ------KHPDYRYR PRPK------RTCI
Mus_musculus_SOX-13 MTNQEKQPYY EEQARLSRQH LEKYPDYKYK PRPK------RTCV
NvSOXD MSNSEKQPYY EEQSRLSKLH MEKHPDYRYR PRPK------RTCI
AgSOXD MTNLEKQPYY EEQAKLSKQH MEKHPDYRYR PRPK------RTCI
AgSOXC LSPEERQPFI EEAERLRKLH TQEYPNYKYR PKKK------QIKG
NvSOXF LTPQDRRPFV EEAERLRVIH MQEHPNYKYR PRRR------KHAAmSOXF
LTPQDRRPYV EEAERLRVIH MQEHPNYKYR PRRRKHAKRA PGAPSSPPSA
DmSox14 LSKDDKQPYI IEAEKLRKLH MIEYPNYKYR PQKK------QTRS
DmSox15 LTPQDRRPYV EEAERLRVIH MTEHPNYKYR PRRR------KQSMmSox7
LTLSQKRPYV DEAERLRLQH MQDYPNYKYR PRRK------KQGMmSox9
LNESEKRPFV EEAERLRVQH KKDHPDYKYQ PRRR------KSVK
AmSOXE2 LSDGEKQPFI EEAERLRNAH KKQHPHYKYQ PRRR------KP--
NvSOXE2 LSDGEKQPFI EEAERLRSAH KKQHPHYKYQ PRRR------KA--
GQ6VMKX01CVUP8 ------
TcSOXC LKDDERQPFI EEAERLRQLH QREYPDYKYR PRKK------TTKNvSOXC
LDEAERRPFI EEAERLRQLH MMEYPDYKYR PRKK------TSKAmSOXC
LDEAERRPFI EEAERLRQLH MVEYPDYKYR PRKK------TSKS
MmSox11 LKDSEKIPFI REAERLRLKH MADYPDYKYR PRKK------PKTDm100B
LKDSDKKPFM EFAEKLRMTH KQEHPDYKYQ PRRK------KARV
AgSOXE ------
AgSOXdichaete LTEAQKRPFI DEAKRLRATH MKEHPDYKYR PRRK------PKNDmSoxDichaete
LAESEKRPFI DEAKRLRALH MKEHPDYKYR PRRK------PKNMmSox2
LSETEKRPFI DEAKRLRALH MKEHPDYKYR PRRK------TKTDmSoxNeuro
LSESEKRPFI DEAKRLRAVH MKEHPDYKYR PRRK------TKTAgSOXneuro
LSETEKRPFI DEAKRLRAVH MKEHPDYKYR PRRK------TKTGQ6VMKX01ATTSG
-CKFDKRPFI DEAKRLRAVH MKDHPDYKYR PRRK------TKTAmSOXB1
LSETEKRPFI DEAKRLRAVH MKEHPDYKYR PRRK------TKTL
TcSOXB1 LSEAEKRPFI DEAKRLRAVH MKEHPDYKYR PRRK------TKTMITE_
454Assem.6107.C1 LPNEERKPFI DEAKRLREQH MRDHPEYKYR PRRK------PKPDmSox21a
LTEGQKRPFI DEAKRLRALH MKEHPDYKYR PRRK------PKTAmSOX21
LSDTEKRPFI DEAKRLRAMH MKEHPDYKYR PRRK------PKVP
MmSox14 LSEAEKRPYI DEAKRLRAQH MKEHPDYKYR PRRK------PKNAmSOXB2
LSESEKRPFI DEAKRLRALH MKEHPDYKYR PRRK------PKSMITE_
454Assem.sd.9120.C1 -TEEQKRPFI DEAKRLREQH MRDHPEYKYR PRRK------PKPNvSOX21b
LSEEEKLPFI DEAKRLRALH MKEHPDYKYR PRRK------PKTNvSOXB2
LSEGEKRPFI DEAKRLRALH MKEHPDYKYR PRRK------PKSV
AmSOX21b LTEDEKRPFI DQAKRLRAQH MKEYPDYKYR PRRK------PKTDmSox21b
LTEEEKRPFI DEAKRLRAMH MKEHPDYKYR PRRK------PKAAgSOX21b
LTEDEKRPFI DEAKRLRAMH MKEHPDYKYR PRRK------PKPTcSOXB2
LSESEKRPFI DEAKRLRALH MKEHPDYKYR PRRK------PKPMITE_
454Assem.9481.C1 ------AKRLRSIH MVQHPDYKYR PRRR------PK--
AgSOX21a LTEGEKRPFI DEAKRLR--- --DYGDA------
AgSOXF ------
Ixodes_XM_002405835.1 LSEDAKRPFI DEAKRLREQH MRDHPDYKYR PRRK------PKPIxodes_
XM_002415496.1 LSEAEKRPFI DEAKRLRAVH MKEHPDYKYR PRRK------TKTIxodes_
XM_002404083.1 ------
Ixodes_XM_002404066.1 LPMTAKRPYI VEAGRLSSHH AEQHPTYRYK NRRK------SGCIxodes_
XM_002434573.1 LSETDKRPFI EEAKRLRALH MKEHPDYKYK PRRK------PKSM
Ixodes_XM_002409732.1 LSETDKRPFI DEAKRLRALH MKEHPDYKYR PRRK------PKVIxodes_
XM_002416402.1 LSDLERKPYI EEAERLRLLH MQEYPDYKYR PRKK------AKTIxodes_
XM_002415871.1 MSNSEKQPYY EEQSRLSKLH MEKHPDYRYR PRPK------RTCI
501
Xenopus_Sox13 VEGKRLRVGE YKALMKNRRQ DTRSLGS------
Xenopus_Sox7 --KRICKRVD TGFLLGSLSK DQNSVPDTRG CRTAMEKEEN ------
Xenopus_Sox9A NGQTEQEDGA EQTHISPNAI FKALQADSPH SSSSMSEVHS PGEHSGQSQG
Xenopus_Sox11A ---DPSASSK PPALTQSPEK SPKSRSAGRK CPKLKPSHSG SGSKSLSIKS
Xenopus_Sox2 ----LMKKDK YTLPGGLLAP GANAMTS------
Xenopus_Sox14 ----LLKKDR YVFPLPYFGD HDPLKTGLSM SATDSIL------
Strongylocentrotus_XM_781716.2 ------DNN PKKPCLTGNR PSLVPSPDSS NHVSTKALLS AMVGEEITEA
Strongylocentrotus_NM_214473.1 ----LMKRDK YAFPIPCIPT SSPYQVATSQ ADMMNMASAE KARTYLSSHStrongylocentrotus_
NM_214474.1 ----LLKKDK FTLPGIINPQ TGAPVQRGVG DGMHGY------
Strongylocentrotus_XM_001176459.1 -----TTKPE AAKTTSSKPK ANKPKSSSKL TKMNGIVIDQ MHPHQIVQSStrongylocentrotus_
XM_786890.2 -KRQSRSRDG SSGDASSSST PSTPSPTTPQ TNGLPSSAMP TPEGSPRTSStrongylocentrotus_
NM_214472.1 IDGKKLKIGE YKALMRAKRQ EVRHV------
Drosophila_Sox102F VDGKKMRISE YKVLMRNRRA EMRQLWCRTG ------
MITE_454Assem.5595.C1 VDGKKLRISE YKMLMKQRRE EMRAL------
Mus_musculus_SOX-13 VEGRRLRVGE YKALMRTRRQ GARQSYTIP------
NvSOXD VDGKKMRISE YKSLMRQRRN EMRQLWCRDG ------
AgSOXD IDGKKMRISE YKCLMKNRRQ EIRQFWT------
AgSOXC SGSGGAGPAS SPKNGSSSSS SSSSSTGAGS PALSTSSSTG SPDSVSSRDS
NvSOXF ------
AmSOXF TNTTTNRSNP SGTTIHHSMS KMDSYQGIPQ IPWGGHSPIS SLYHQQQQQG
DmSox14 PGSLKPNQDA DGCEARNDTT NNNNSLTTLA INGTTTAGRK SKRSTSTCQS
DmSox15 -KLRAMQPGG KEQSESSPNP GTGGSKSNPK LATPPLATAS SSYTTPTDES
MmSox7 --KRLCKRVD PGFLLSSLSR DQNTLPEKNG IGRGEKEDRG EYSPG-----
MmSox9 NGQAEAEEAT EQTHISPNAI FKALQADSPH SSSGMSEVHS PGEHSGQSQG
AmSOXE2 ------KSE EQMGIVMHRT ALSSPATSLD STNSSECAYP RLYTDAG---
NvSOXE2 ------KSD EQTSTTSSSS SHRSNGSSAS LGNQDIVNPS SDCAYTRLYGQ6VMKX01CVUP8
------
TcSOXC ------PA PKSATSSKKS SKKSPKVQKN DNNNNSSNNS NAIVKERLYNvSOXC
----PAAQGQ PSQLLDYTPT PPIATAKVPS SPSCDT------
AmSOXC ATCIGQKTKE GGGGKKLRKS GLSSMGGGGG GGGGSMSSKN H------
MmSox11 ------DPAA KPSAGQSPDK SAAGAKAAKG PGKKCAKLKA PAGKA-----
Dm100B LPSQQSGEGG SPGPEMTLSA TMGSSGKPRS SNSNGQRRAG KGNAAADL--
AgSOXE ------
AgSOXdichaete ------PLASAAN GLGALGAMQQ SGKAGSLGSS ------
DmSoxDichaete ---PLTAGPQ GGLQMQAGGM GQQKLGAGPG AGAGGY------
MmSox2 ----LMKKDK YTLPGGLLAP GGNSMASGV------
DmSoxNeuro -----LTKTK EKYPMGGLMP GQTVGGGAPG EPVTPTRVQG QPGQNQSLNAgSOXneuro
-----LTKAK EKYPLGV--- GSLLGAGQTN EGSGMRGSGS STTLAAQQAGQ6VMKX01ATTSG
-----LMKKD KPYSLASGLD PLTAD------
AmSOXB1 ------LKK DKFPLGGGVA GVGGMLGVDQ RQVGGNGGPQ QTQLS-----
TcSOXB1 ----LLKKDK YPLGASSLIP TSDPTRTAPS AVQQVSS------
MITE_454Assem.6107.C1 ------ASPAMSPVA PPTTM------
DmSox21a ------LNK SPVPGGGGGG GGGGANGGVN AGGAGNSGPS GP------
AmSOX21 VSVVPGSKTT SMSPGGFPSF PLPPYFAAPA APVSHHHHHP HP------
MmSox14 ----LLKKDR YVFPLPYLGD TDPLKAAGLP VGA------
AmSOXB2 ---LVKKENK FGFSISPLMS SGESLGN------
MITE_454Assem.sd.9120.C1 ------ATPVMSSAV AGDLINNNNN ------
NvSOX21b -----HRKEG YPYSIPYPSV PMDALRASMP GGIGQASM------
NvSOXB2 IKK----ENK FGFALSPLTM PGSGGTGEHH -----HHHGP LGSISRGLLAmSOX21b
-----LRKEG YPYSIPYPSV PMDAFRTGMA GSMGQAGM------
DmSox21b -----LRRDG YPYPMPYPSV PVEALRAGIT PGYFAPGPTA AAYHLGSHLAgSOX21b
-----IRRDG YPYPMTYPSV PVDALRA------
TcSOXB2 ---LLKKEPK FGFSISPLIS PPMDGQSIPR SMVPPISVAT SLPSLLS---
MITE_454Assem.9481.C1 ------PNQTSAN GGQPA------
AgSOX21a ------KSD LQFIVTV------
AgSOXF ------
Ixodes_XM_002405835.1 ---PAPKKPD APYPFAMPAY MPGGIEHCRA YLQQHQQHMM ------
Ixodes_XM_002415496.1 ----LLKKDK YPLAGGLLSG DATRPNSAPQ VARDMY------
Ixodes_XM_002404083.1 ------
Ixodes_XM_002404066.1 ------
Ixodes_XM_002434573.1 LKKE---GHR FPFALPYIPS PSDYLGLPRS LF------
Ixodes_XM_002409732.1 ----TLGTSS SPQTLQKQKT ATGGLSAQDN PFFSFESVSR F------
Ixodes_XM_002416402.1 --C----VKT PERPAPVAKA SHHHAAVTPH TSSSSNSSSG SSKHSSHHHIxodes_
XM_002415871.1 VDGKKLRISE YKSLMRARRQ EMRNLWYREG SL------
551
Xenopus_Sox13 ------LQC PPS------PSGFS------
Xenopus_Sox7 ------GGY PGA------ALSDIR------
Xenopus_Sox9A P------PTP PTT------PKTDIQPG KPDLKREGRP
Xenopus_Sox11A E------YSG GSD------EYVFGSPK ASGKAAAAAV
Xenopus_Sox2 ------GVG GSL------GAGVNQ------
Xenopus_Sox14 ------GAS EKA------RAFFPP------
Strongylocentrotus_XM_781716.2 NLKERTEKLG MMMGGAGGQG PPT------PPTTPKND LECTRPNKRQ
Strongylocentrotus_NM_214473.1 ------QHH AAA------AAAAAS------
Strongylocentrotus_NM_214474.1 ------QHL NGY------MNGYPS------
Strongylocentrotus_XM_001176459.1 ------GRI EKI------PKLKLT------
Strongylocentrotus_XM_786890.2 ------PTP MDN------LNGNMPGG LIDNCKYKLP
Strongylocentrotus_NM_214472.1 ------
Drosophila_Sox102F ------GVS GGS------GSLCAD------
MITE_454Assem.5595.C1 ------
Mus_musculus_SOX-13 ------PQA GQA------QVSSDI------
NvSOXD ------
AgSOXD ------
AgSOXC CGSSSSSSSS SSSSSS-AKS PAA------PTGKRSRT ASGKVSKGGA
NvSOXF ------KRA PGA------PSS------
AmSOXF IQEYKSESNS LYGSPYTPII HSPDISPVAS PEPDGDGTHL PSNQNPDPER
DmSox14 GSASKRLRND SGDTSSKPKY EVK------MESAEQLN SADIILPSAD
DmSox15 TCNSTNQNHG QSTPGGLYEQ PLK------PTYSPSSV DCYSNADSTE
MmSox7 ------ATL PGL------HSCYREGA AAAPGSVDTY
MmSox9 ------PPT PPT------TPKTDVQA GKVDLKREGR
AmSOXE2 ------IKM YER------PTYHDN------
NvSOXE2 ------PES PVN------KPMPVN------
GQ6VMKX01CVUP8 ------
TcSOXC ------ARR SAL------PESTSS------
NvSOXC ------PDS PES------ASFYDD------
AmSOXC ------SRN HDN------NNNNNSNN NSETSGTGNS
MmSox11 ------GAG KAA------QPGDCA------
Dm100B ------GSC AST------ISHANVGS NSSDVFSNEA
AgSOXE ------
AgSOXdichaete ------YPF PQL------PPYFAP------
DmSoxDichaete ------NPF HQL------PPYFAP------
MmSox2 ------GVG AGL------GAGVNQ------
DmSoxNeuro ------GSG GSA------AAAAAA------
AgSOXneuro ------AAA AAA------AAAAAA------
GQ6VMKX01ATTSG ------PSR SSA------GPTSAA------
AmSOXB1 ------RDV YQM------PNGYMP------
TcSOXB1 ------RDM YQM------PNGYMP------
MITE_454Assem.6107.C1 ------GQS FAS------SLNYPQ------
DmSox21a ------GSV GSP------KDMQPQ------
AmSOX21 ------LDY PPL------PSYFGS------
MmSox14 ------SDG LLS------APEKAR------
AmSOXB2 ------ISR SLL------PPLAPP------
MITE_454Assem.sd.9120.C1 ------
NvSOX21b ------SSY YGP------AAAYGSLS AASMAAAAAA
NvSOXB2 ------PPL GPP------GMNHPL------
AmSOX21b ------GSY YGP------AAAYGSLS AASMAAAAAA
DmSox21b ------GQT STP------TTTQAT------
AgSOX21b ------
TcSOXB2 ------HHH PDQ------DPLKIPRS L------
MITE_454Assem.9481.C1 ------HNA ASX------PPAXTP------
AgSOX21a ------
AgSOXF ------
Ixodes_XM_002405835.1 ------MNV PSP------PLYQED------
Ixodes_XM_002415496.1 ------PMN GYM------PNGYPP------
Ixodes_XM_002404083.1 ------
Ixodes_XM_002404066.1 ------
Ixodes_XM_002434573.1 ------PHH PRL------AIPFPQ------
Ixodes_XM_002409732.1 ------GRL DSQ------KPATTR------
Ixodes_XM_002416402.1 ------GTH HKS------HHHHHHHH HHHHHHKSSK
Ixodes_XM_002415871.1 ------GLL DTP------PSLVSP------
601
Xenopus_Sox13 ------
Xenopus_Sox7 ------H YRETPSNGNK YDQTYPYG------
Xenopus_Sox9A LQENGRQPPR IDFRDVDIGE LSSEVISTIE IFDVNEFD------
Xenopus_Sox11A KCVFMDEDEE EEEEEEDDEE EEDELQIRIK QEEDDEPL------
Xenopus_Sox2 ------RMDTYAHMN GWTNGGYG------
Xenopus_Sox14 ------TSTPYS------
Strongylocentrotus_XM_781716.2 KYSLKVKTEM PVDFAGVDVR DFGGDIMGME EFSSEELD------
Strongylocentrotus_NM_214473.1 ------QYSVLEHA QKLECPTSLI RDFPHHPA------
Strongylocentrotus_NM_214474.1 ------MM QDQLSHLPSH SYGAHQAA------
Strongylocentrotus_XM_001176459.1 ------ID KKFRENMKAS KIVELVPS------
Strongylocentrotus_XM_786890.2 SFQSIYDPLS SNTLTQYNKS DSGHMVGLPT PEMSPIDH------
Strongylocentrotus_NM_214472.1 ------
Drosophila_Sox102F ------
MITE_454Assem.5595.C1 ------
Mus_musculus_SOX-13 ------
NvSOXD ------
AgSOXD ------
AgSOXC SGGSLKGKKQ LILDELGQPT MAAVATAASM PPLAAQPDCY SLAATKLLPN
NvSOXF ------
AmSOXF DLMEGSSKQH SEISEQTKRY TFMSTDNQLH TGHAGGTS-- ---ISSCQNS
DmSox14 NLISYQSSEY LPLSTLSNAD CDEKLHSELS SGPLESRE------
DmSox15 QIESLAANCP PALLNESSPT GGGYDNSLLL KKLTKPSP------
MmSox7 PYGLPTPPEM SPLDALEPEQ TFFSSSCQEE HGHPHHLP------
MmSox9 PLAEGGRQPP IDFRDVDIGE LSSDVISNIE TFDVNEFD------
AmSOXE2 ------KINYDVSRS SWSNDTSK------
NvSOXE2 ------TYGAELAPRV PYEMAKYT------
GQ6VMKX01CVUP8 ------
TcSOXC ------KLKERL DLSPVMTP------
NvSOXC ------HFIDCNSQFA TAIHQQQQ------
AmSOXC VGGGIAVKRL QTHSVGSKPV SRLKVRLALD KRPPLDYT------
MmSox11 ----AGKAAK CVFLDDDDED DDEDDELQLR PKPDADDD------
Dm100B FMKSLNSACA ASLMEQSLIE TGLDSPCSTA SSMSSLTP------
AgSOXE ------
AgSOXdichaete ------AHPL QQLEQHYP------
DmSoxDichaete ------S HHLDQGYP------
MmSox2 ------RMDSYAHMN GWSNGSYS------
DmSoxNeuro ------AAAAAQQAR QDMYQMNAPN GYMPNGYM------
AgSOXneuro ------N RDMYHQMPPN GYMPNGYT------
GQ6VMKX01ATTSG ------
AmSOXB1 ------NGYMMHDPTA AYQQHVAYGS HMGGAAAA------
TcSOXB1 ------NGYM MHDPGAYQ------
MITE_454Assem.6107.C1 ------
DmSox21a ------
AmSOX21 ------
MmSox14 ------
AmSOXB2 ------SHHTLM SHEDLKIP------
MITE_454Assem.sd.9120.C1 ------
NvSOX21b AAQQSAAAMS AGLTAPAQVV SSMDAMKYSM EADKYRAA------
NvSOXB2 ------IG HADDLKIP------
AmSOX21b AAQQSAAAMS AGLAAPAQVV SSMDAMKYSM EADKYRAA------
DmSox21b ------LSGQMDKF ALERSSYLSN SSQASAYS------
AgSOX21b ------
TcSOXB2 ------
MITE_454Assem.9481.C1 ------
AgSOX21a ------
AgSOXF ------
Ixodes_XM_002405835.1 ------KRN ASSPQSSS------
Ixodes_XM_002415496.1 ------AAAAAMM HDAYQGYG------
Ixodes_XM_002404083.1 ------
Ixodes_XM_002404066.1 ------
Ixodes_XM_002434573.1 ------HPVMG AGLPPLSP------
Ixodes_XM_002409732.1 ------
Ixodes_XM_002416402.1 KSAPMTATLN PRLKLKLTID DKFKKSISRS KHVPLSTG------
Ixodes_XM_002415871.1 ------
651
Xenopus_Sox13 ------
Xenopus_Sox7 ------
Xenopus_Sox9A ------
Xenopus_Sox11A ------
Xenopus_Sox2 ------
Xenopus_Sox14 ------
Strongylocentrotus_XM_781716.2 ------
Strongylocentrotus_NM_214473.1 ------
Strongylocentrotus_NM_214474.1 ------
Strongylocentrotus_XM_001176459.1 ------
Strongylocentrotus_XM_786890.2 ------SDN
Strongylocentrotus_NM_214472.1 ------
Drosophila_Sox102F ------
MITE_454Assem.5595.C1 ------
Mus_musculus_SOX-13 ------
NvSOXD ------
AgSOXD ------
AgSOXC SPESATLYDE RSLISPEPTF GSFTEGTPLF IRTPDHSVFA VDESSHFEHE
NvSOXF ------
AmSOXF GAYTDTLTYK KSVSYLNFER QPSSIAAVGI ANGMMVSCNK LRSGFENVGS
DmSox14 ------NLSEVVN
DmSox15 ------S RAAKSRQEKL AKSEEKNKGS QSQGQSQQGI
MmSox7 ------
MmSox9 ------
AmSOXE2 ------
NvSOXE2 ------
GQ6VMKX01CVUP8 ------
TcSOXC ------
NvSOXC ------
AmSOXC ------
MmSox11 ------
Dm100B ------
AgSOXE ------
AgSOXdichaete ------
DmSoxDichaete ------
MmSox2 ------
DmSoxNeuro ------
AgSOXneuro ------
GQ6VMKX01ATTSG ------
AmSOXB1 ------
TcSOXB1 ------
MITE_454Assem.6107.C1 ------
DmSox21a ------
AmSOX21 ------
MmSox14 ------
AmSOXB2 ------
MITE_454Assem.sd.9120.C1 ------
NvSOX21b ------
NvSOXB2 ------
AmSOX21b ------
DmSox21b ------
AgSOX21b ------
TcSOXB2 ------
MITE_454Assem.9481.C1 ------
AgSOX21a ------
AgSOXF ------
Ixodes_XM_002405835.1 ------
Ixodes_XM_002415496.1 ------
Ixodes_XM_002404083.1 ------
Ixodes_XM_002404066.1 ------
Ixodes_XM_002434573.1 ------
Ixodes_XM_002409732.1 ------
Ixodes_XM_002416402.1 ------
Ixodes_XM_002415871.1 ------
701
Xenopus_Sox13 ------
Xenopus_Sox7 ---LPTPPEM SPLEAIDQDQ SFYSTSCSED CHSHINGAVY PPEYSRSPIL
Xenopus_Sox9A ---QYLPPNG HPGVGSTQAS YTGSYGISST PSATTGAGPA CMSKQQ----
Xenopus_Sox11A ---RQYNVAK VPASPTLSSS SAESVEGASM YEDIR------
Xenopus_Sox2 ---MMQEQLG YPQHPGLNAH NAPQMQPMHR YDVSALQYNS MSSSQTYMNXenopus_
Sox14 ---LLDPSHF SSTTIQKMTE MPHTLATS------
Strongylocentrotus_XM_781716.2 ---QYIVQTI ASVTSSQPMP GQQGMVRQSC AMPPFTTHST YPMSNVNTQS
Strongylocentrotus_NM_214473.1 ---LYPPPHM YPTSAGAVPG SAV------
Strongylocentrotus_NM_214474.1 ---QMANSGL HHRYDMAQLG YPAMSTTHAA SYLSPAAAN------
Strongylocentrotus_XM_001176459.1 ---QLTPPAK VPASPTGSNT DPCNEQSLYE DYANIQHTYE ------
Strongylocentrotus_XM_786890.2 VFTFPPSSSS DTLMQPNLSG VQATSNVFAP IHSPGMVIKS EPGVYEFQQQ
Strongylocentrotus_NM_214472.1 ------
Drosophila_Sox102F ---ACPKGSG GSNSQVAV------
MITE_454Assem.5595.C1 ------
Mus_musculus_SOX-13 ---LFPRAAG LPLARPLVEH Y------
NvSOXD ---GPEMGFL SPVQSDLSGG QQPQ------
AgSOXD ------
AgSOXC AKGFRYAHGA TPDLTGGDSV GSPLGHTNHT TCSTASATNT TSSSPATTVT
NvSOXF ------
AmSOXF VTGTFYPPVA SPHDQSLQHY TSTQSSKTAN YSMQSSVESN YNPVQC----
DmSox14 RFLPLFLGGN EDSQLGVSSL TQSQHNQSDP TAGLMDNISD ISPINDREEL
DmSox15 YAATYPLAPT SVAVVAARGM YVTCNNRGLL DHGHSVKGTF YPPVSVSEDD
MmSox7 ---HLPGPPY SPEFTPSPLH CSHPLGSLAL ------
MmSox9 ---QYLPPNG HPGVPATHGQ VTYTGSYGIS STAPTPATAG HVWMSKQQ--
AmSOXE2 ---YPADHSI VESKGPYEGG RYGESNVGKS CYV------
NvSOXE2 ---IDQHGLT HGKCLEATPR YADATAHHHH HHHHHSLK------
GQ6VMKX01CVUP8 ------
TcSOXC ---LPLPPVS ILAKVPSSPS CD------
NvSOXC ---QLLSSVR TYTHQDMQNL ARGFHEQQQQ QQQQQRNACH PD------
AmSOXC -PSPPIVTAK IPSSPSCVTP DSPESASFYE DNLLECGGGS TV------
MmSox11 ---DDEPAHS HLLPPPTQQQ PPQLLRRYSV AKVPASPTLS SAA------
Dm100B ---PATPYNV APSNAKASAA NNPSLLLRQL SEPVANAGDG YGVLLEAGRE
AgSOXE ------
AgSOXdichaete ---VPYFGSF DPLTLQKLHQ SQQQS------
DmSoxDichaete ---VPYFGGF DPLALSKLHQ SQAAAAAAVN ------
MmSox2 ---MMQEQLG YPQHPGLNAH GAAQMQPMHR YDVSALQYNS MTSSQTYMNDmSoxNeuro
---MHADPAG AAAYQTSYMG QHYAAQRYDM GHMYNNGYAM YQTVS-----
AgSOXneuro ---MMHDPSS AAAYQSQQHY MSNYHHHHRY EMGQMAAAAA ASGTTAGSLN
GQ6VMKX01ATTSG ------
AmSOXB1 ---AAASAAG YPRYDMGHHM GGGSPSPINS YMNGYGGYGS TTVPG-----
TcSOXB1 ---QQYTGSN YGRYDMSQMQ YMNGYGYGA------
MITE_454Assem.6107.C1 ---LKDKEVN YPSNFRTWDT WEL------
DmSox21a ---LSPLGQS LPHLHGHPHQ SPYQSHPHHP HPHPHHVQLA AAT------
AmSOX21 ---AFDAVHL SKLVAGGGGT GSTSSSAAAA AA------
MmSox14 ---AFLPPAS APYSLLDPAQ FSSSAIQKMG EVPHTLATS------
AmSOXB2 ---RFFPPFP YPLYPIQHKL GEEFNGGKLA ADLALQALYG GGTF------
MITE_454Assem.sd.9120.C1 ------
NvSOX21b ---YMPPSTL AMSMYPDTKY LDSSSKSYLD RSYLDSAKAY LEQSKLYMDH
NvSOXB2 ---RFFPPFP YHLYNPLQHK MGEDMGGGKL AADLAFQAIY GSGGSF----
AmSOX21b ---YMPPSTL TMSMYSDPKY LDSSPKSYLD RSYLDSATKA Y------
DmSox21b ---AYLDPSV LTKAYFDSKM YQDRAANYAF DISKIYGAQQ HAAAHHQQQQ
AgSOX21b ------
TcSOXB2 ---FPPLPYL YPFRHPEESK FAAELALLYS NSHL------
MITE_454Assem.9481.C1 ---PMPPSSF DSKPLGLIPS NG------
AgSOX21a ------
AgSOXF ------
Ixodes_XM_002405835.1 ---SPLPPSA YVSYPADVKP FSADVKPFSA PTYKTAELGH A------
Ixodes_XM_002415496.1 ----SQMHGA YPRYDPQLPY VNGSYASAGH ------
Ixodes_XM_002404083.1 ------
Ixodes_XM_002404066.1 ------
Ixodes_XM_002434573.1 ---VPRPSSR SSCHQDDLNR EAASSDDGRK LSPPSPLATS SPPTSST---
Ixodes_XM_002409732.1 ---NGLGVGG SHMSPASQQH WLNSSLAKLR GEPTPIYFK------
Ixodes_XM_002416402.1 ---QLTPPAK VPCSPSADEP ASPESANLSL YEDMVVDVKP TMVGL-----
Ixodes_XM_002415871.1 ------
751
Xenopus_Sox13 ------SQSLLGNLS QSPQECNIQV
Xenopus_Sox7 CSHLSQVP------IPQPGSSMI PPVPTCPPAY
Xenopus_Sox9A ------QQQPQQHSL STLNSEQSQS
Xenopus_Sox11A ------NGTRLYYNF KNITKQSTIP
Xenopus_Sox2 ------GSPTYSMSY SQQGAPGMSL
Xenopus_Sox14 ------TLPYASTLG YQNGAFGGLS
Strongylocentrotus_XM_781716.2 STGRQWMGRP HP------NGGNTSPLQ TTVLDNVNSK
Strongylocentrotus_NM_214473.1 ------GKLPGGSAA AAAAAAAAGY
Strongylocentrotus_NM_214474.1 ------YSAAYSQAA MMHHAPSGTS
Strongylocentrotus_XM_001176459.1 ------MQRYEFGVP SGATSTTCSS
Strongylocentrotus_XM_786890.2 CV------VDNAELTNQ MNVTATMSAS
Strongylocentrotus_NM_214472.1 ------YY TRDGEHMIRA
Drosophila_Sox102F ------AAAAAVYHL QDMASSAAST
MITE_454Assem.5595.C1 ------CG
Mus_musculus_SOX-13 ------DPQGLDPNM PVIINTCSLR
NvSOXD ------QHPSGAGPS ARPSVSPPAT
AgSOXD ------
AgSOXC VHHGAHVPSC NSPLPQQHHN QHQQHNQQQH NNTNNNNNNN NSLQINNNHL
NvSOXF ------
AmSOXF ------ANRQQSMGI RGAAEGCSGV
DmSox14 TEEVMRYLPY LEVNPSSDGL TLKVESSSLL GKPLNEPVFD SEDNIVNDAN
DmSox15 NSTSMRNSIS ALQQHCNVVT STPSSSGGTM PTSEMSSYTV SMADNCGNLR
MmSox7 ------GQSPGVSMM SSVSGCPPSP
MmSox9 ------APPPPPQQP PQAPQAPQAP
AmSOXE2 ------DAKCYETVK YHHEVSAAVK
NvSOXE2 ------YPELQSKSY DSPIPGTGTR
GQ6VMKX01CVUP8 ------
TcSOXC ------IPDSPESAT IYDDSLAPLH
NvSOXC ------DVFIKQEPQ LHMGNLVVGS
AmSOXC ------GRLMANDNT DRRATIRATP
MmSox11 ------ESPEGASLY DEVRAGGRLY
Dm100B YVAIGEVNYQ GQSAGVQ------SGAEGGGAG QEMDFLENIN
AgSOXE ------
AgSOXdichaete ------VHQAGHSPV GGLGGDSGKQ
DmSoxDichaete ------NQGQQQGQA PPQLPPTSLS
MmSox2 ------GSPTYSMSY SQQGTPGMAL
DmSoxNeuro ------GGQTSPYGS SLQQPGSPSP
AgSOXneuro STVS------GGQTSPYGG SGGGLQQPGS
GQ6VMKX01ATTSG ------
AmSOXB1 ------GSPSPYHQA QPGSQMSSHS
TcSOXB1 ------TVPQSAGSP YGMQQTSSHS
MITE_454Assem.6107.C1 ------RIPRSLFEL PSPHILLAMT
DmSox21a ------LSAKYGFGS PLELSLPRLP
AmSOX21 ------AAAADAANN NAASAAAVVN
MmSox14 ------ALPYASTLG YQNGAFGSLS
AmSOXB2 ------YSSHQTMSW PGLSTATCLQ
MITE_454Assem.sd.9120.C1 ------HHHNNNNNQ PGFPNANEMK
NvSOX21b QQ------QQQHSSYEP NKLYEESSPG
NvSOXB2 ------YSGHQGMAW PGITAPSYLQ
AmSOX21b ------FEQSKLYMD QKPAIADYNR
DmSox21b QQ------QQQQQQQQQ QLLLSGGGGS
AgSOX21b ------
TcSOXB2 ------YPPSINWPI NNLASNVNGP
MITE_454Assem.9481.C1 ------LPPHPLLME MILGKSAFGV
AgSOX21a ------
AgSOXF ------
Ixodes_XM_002405835.1 ------SIYAGLYGA GPGQAGGLMS
Ixodes_XM_002415496.1 ------YASMPQMQL KSSAESSPTP
Ixodes_XM_002404083.1 ------
Ixodes_XM_002404066.1 ------
Ixodes_XM_002434573.1 ------STTPTSDPT PGFKAFVPSH
Ixodes_XM_002409732.1 ------SDIAAPTPL YSTQAPATSP
Ixodes_XM_002416402.1 ------ISAASPSS- STTSSCSSVS
Ixodes_XM_002415871.1 ------TSVASLLGA PSSAPSMSAA
801
Xenopus_Sox13 VTSQCLMSHE LHG------AIH------
Xenopus_Sox7 YSSSYHSIHN YHA------HLG------QLS PPPEHPHYDT
Xenopus_Sox9A QQRTHIKTEQ LSP------SHY- ----SDQQQQ HSPQQLNYSS
Xenopus_Sox11A QATITLAPRP APT------TTS------PAGSHELLFD
Xenopus_Sox2 GSMGSVVKSE SSS------SPP------VVT SSSHSRAPCQ