Supplement 1. Summary of reasons for exclusion of randomized clinical trials.

First Author
(Year) / Reason for exclusion
Bian (2004)1 / Combined point injection with moxibustion (n=44)
Chen (2002)2 / Which transcutaneous electrical nerve stimulation was the treatment group (n=66)
Dou (2004)3 / Used acupuncture treatment as a control (n=120)
Jin (2003)4 / Used both acupuncture and moxibustion on the treatment group (n=66)
Liu (2010)5 / Acupuncture combined point injection (n=102)
Liu (2008)7 / Acupuncture combined point injection and moxibustion (n=102)
Liu (1996)6 / AT vs. AT (n=70)
Mehling (2007)9 / Combined acupuncture and massage (n=138)
McDonugh (2008)8 / Included cancer pain with other types of pain and did not discuss them separately (n=80)
Xiao (1994)10 / EA vs. AT (n=50)
Zhang (2010)11 / Group I (6 cases received acupuncture first and then western medicine) vs. Group II (5 cases received western medicine first and then acupuncture) (n=11)

References

1. Bian D, Zhang NS, CHeng ZD, CHen YG: Effect of acupoint injection and moxibustion on β-endorphin in peripheral blood of patients with carcinous pain. Liaoning J Tradit Chin Med 31:246-247, 2004

2. Chen LL, Hu HQ, Shen AX, Wang JL: Therapeutic effect of electric stimulation on patients with carcinous pain. Zhejiang J Integr Tradit Chin West Med 12:516, 2002

3. Dou ZP, Lei YM, Zheng GA: Observation on the abirritation of zusanli(st36) point injection on late gastric carcinoma. Zhejiang J Integr Tradit Chin West Med 19:538-539, 2004

4. Jin ZX: Clinical analysis of two-phase acupuncture-moxibustion therapy for large intestine cancer in 27 cases. Shanghai J Tradit Chin Med 37:48-49, 2003

5. Liu H: Efficacy of acupuncture combine with acupoint injection treatment for liver cancer pain. J Hebei Tradit Chin Med Pharmacol 25:37-38, 2010

6. Liu S, Wang L, Niu JQ, Wang GJ: Acupuncture stop cancer pain. Shanghai J of Acup Moxi 15:42-43, 1996

7. Liu XY, Dong RP: 51 cases with liver cancer pain treated with acupuncture and drug injection at points. Shanxi J Tradit Chin Med 29:347-348, 2008

8. McDonough SM, Liddle SD, Hunter R, Walsh DM, Glasgow P, Gormley G, Hurley D, Delitto A, Park J, Bradbury I, Baxter GD: Exercise and manual auricular acupuncture: A pilot assessor-blind randomised controlled trial (the acupuncture and personalised exercise programme (apep) trial). BMC Musculoskelet Disord 6:31, 2008

9. Mehling WE, Jacobs B, Acree M, Wilson L, Bostrom A, West J, Acquah J, Burns B, Chapman J, Hecht FM: Symptom management with massage and acupuncture in postoperative can cerpatients: A randomized controlled trial. J Pain Symptom Manage 33:258-266, 2007

10. Xiao JH, Li LJ: Observation of 50 cases of cancer pain relieved by acupuncture. Zhen Ci Yan Jiu 19:139-140, 1994

11. Zhang X, Fan XN, Ding L, Zhang HT, Wu LZ, Wang HR: Acupuncture treatment of regulating spirit, activating blood and relieving pain for thalamic pain. Zhongguo Zhen Jiu 30:367-370, 2010