1

SM:Additional file1 LysRS2 - gene tree

The order of presentation of the data matches the order in Figure 3and its legend in the article

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Phylum Class Species Source LysRS2

Accession Nr.

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Crenarchaeota ThermoproteiSulfolobus solfataricus NCBIP95970

Crenarchaeota ThermoproteiSulfolobus tokodaii NCBI BAB67182

Crenarchaeota ThermoproteiPyrobaculum aerophilumSwiss-ProtQ8ZWD4

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Clamidiae ClamidiaeChlamydia muridarum NCBIAAF39039 (6)

Clamidiae ClamidiaeChlamydia trachomatis NCBIO84786

Clamidiae ClamidiaeChlamydophila caviae NCBIAAP05580

Clamidiae ClamidiaeChlamydophila abortus NCBICAH64249

Clamidiae ClamidiaeChlamydophila pneumoniae NCBIAAD19069

Clamidiae ClamidiaeParachlamydia sp NCBICAF23952

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Proteobacteria d-proteobacteriaBdellovibriobacteriovorusSwiss-ProtQ6MKP9

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Dein. -thermus DeinococciThermus thermophilus NCBIP41255

Dein. -thermus DeinococciDeinococcus radioduransSwiss-ProtQ9RXE1

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Aquificae AquificaeAquifex aeolicus NCBIO67258

Euryarchaeota MethanomicrobiaMethanosarcina acetivoransSwiss-ProtQ8TSN5

Euryarchaeota MethanomicrobiaMethanosarcina mazeiSwiss-ProtQ8PVP6

Euryarchaeota MethanomicrobiaMethanosarcina barkeriSwiss-ProtQ9C4B9

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Thermotogae ThermotogaeThermotoga maritimaSwiss-ProtQ9X231

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Firmicutes Clostridia Clostridium acetobutylicumSwiss-ProtQ97EB7 (55)

Firmicutes Clostridia Clostridium perfringens NCBIBAB82171

Firmicutes Clostridia ThermoanaerobactertengcongensisSwiss-ProtQ8R7N1

Firmicutes BacilliBacillus licheniformis NCBIAAU21730

Firmicutes BacilliBacillus subtilis NCBIBAA05316

Firmicutes BacilliBacillus cereusSwiss-ProtQ63HC2

Firmicutes BacilliBacillus anthracis NCBIAAP24131

Firmicutes BacilliGeobacillus kaustophilusSwiss-ProtQ5L440

Firmicutes BacilliGeobacillus stearothermophilus NCBIBAA88691

Firmicutes BacilliBacillus haloduransSwiss-ProtQ9KGG4

Firmicutes BacilliBacillus clausii NCBIBAD62660

Firmicutes BacilliStaphylococcus haemolyticus NCBIBAE05802

Firmicutes BacilliStaphylococcus epidermidis NCBIAAO05908

Firmicutes BacilliStaphylococcus aureusSwiss-ProtQ5HIF7

Firmicutes BacilliOceanobacillus iheyensisSwiss-ProtQ8EU10

Firmicutes BacilliExiguobacterium sp NCBIEAM86789

Firmicutes BacilliListeria monocytogenesSwiss-ProtQ724I4

Firmicutes BacilliListeria innocuaSwiss-ProtQ92F47

Firmicutes MolicutesMycoplasma pneumoniae NCBIAAB96206

Firmicutes MolicutesMycoplasma genitalium NCBIP47382

Firmicutes MolicutesMycoplasma gallisepticum NCBIAAP56425

Firmicutes MolicutesUreaplasma urealyticum NCBIAAF30467

Firmicutes MolicutesMycoplasma mycoides NCBICAE76722

Firmicutes MolicutesMesoplasma florumSwiss-Prot Q6F287

Firmicutes MolicutesMycoplasma synoviae NCBIAAZ44018

Firmicutes MolicutesMycoplasma fermentans NCBIAAC43988

Firmicutes MolicutesMycoplasmapulmonis NCBICAC13563

Firmicutes MolicutesMycoplasmahominis NCBIS69892

Firmicutes MolicutesMycoplasmamobile NCBIAAT27530

Firmicutes MolicutesMycoplasmahyopneumoniae NCBIAAZ44294

Firmicutes MolicutesOnion.yellowsphytoplasma NCBIBAD04674

Firmicutes Bacilli Streptococcus thermophilus NCBIZP_00388129

Firmicutes BacilliStreptococcus pneumoniaeSwiss-ProtQ97RS9

Firmicutes BacilliStreptococcus agalactiae NCBIAAM99637

Firmicutes BacilliStreptococcus mutans NCBIAAN58493

Firmicutes BacilliLactococcus lactisSwiss-ProtQ9CII7

Firmicutes BacilliEnterococcus faecalisSwiss-ProtQ839A8

Firmicutes BacilliLactobacillus plantarumSwiss-ProtQ88Z28

Firmicutes BacilliPediococcus pentosaceus NCBIZP_00323784

Firmicutes BacilliLactobacillus casei NCBIZP_00384083

Firmicutes BacilliLeuconostoc mesenteroides NCBIZP_00064363

Firmicutes BacilliOenococcus oeni NCBIZP_00319903

Fusobacteria FusobacteriaFusobacterium nucleatumSwiss-ProtQ8RG52

Firmicutes Clostridia Desulfitobacterium hafniense NCBIEAM94676

Firmicutes Clostridia Syntrophomonas wolfei NCBIEAO22861

Bacteroidetes BacteroidetesBacteroides thetaiotaomicron NCBIAAO77229

Bacteroidetes BacteroidetesBacteroidesfragilis NCBICAH09283

Bacteroidetes BacteroidetesCytophaga hutchinsonii NCBIZP_00310321

Chlorobi Chlorobia Chlorobiumlimicola NCBIEAM42982

Chlorobi ChlorobiaChlorobiumphaeobacteroides NCBIEAM34364

Chlorobi ChlorobiaProsthecochloris vibrioformis NCBIEAO14908

Chlorobi ChlorobiaPelodictyon phaeoclathratiforme NCBIEAN25096

Chlorobi ChlorobiaProsthecochlorisaestuarii NCBIEAN21753

Chlorobi ChlorobiaChlorobium tepidum NCBIAAM72616

Spirochaetes SpirochaetesLeptospirainterrogansSwiss-ProtQ8F4P5

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Planctomycetes PlanctomycetaciaRhodopirellula baltica NCBICAD77044

Proteobacteria a-proteobacteriaAgrobacterium tumefaciens NCBINP_534951

Proteobacteria a-proteobacteriaSinorhizobium meliloti NCBICAC47483

Chloroflexi DehalococcoidetesDehalococcoidesethenogenes NCBIAAW40144

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Acidobacteria AcidobacteriaSolibacter usitatus NCBIEAM57887 (3)

Proteobacteria d-proteobacteriaAnaeromyxobacterdehalogenans NCBIEAL80760

Actinobacteria ActinobacteriaSymbiobacteriumthermophilumSwiss-ProtQ67S33

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Cyanobacteria NostocalesAnabaena variabilis NCBIZP_00161636 (9)

Cyanobacteria NostocalesNostoc sp NCBIBAB75770

Cyanobacteria ChroococcalesSynechococcus elongates NCBIZP_00164084

Cyanobacteria ChroococcalesSynechocystis sp NCBIP73443

Cyanobacteria ChroococcalesThermosynechococcuslongatus NCBIBAC07765

Cyanobacteria ProchloralesProchlorococcus marinusSwiss-ProtQ7UZP0

Cyanobacteria ChroococcalesSynechococcus spSwiss-ProtQ5N1D9

Cyanobacteria GloeobacteriaGloeobacter violaceusSwiss-ProtQ7NG18

Cyanobacteria OscillatorialesTrichodesmium erythraeum NCBIEAO28784

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Actinobacteria ActinobacteriaLeifsonia xyli NCBIAAT89834 (15)

Actinobacteria ActinobacteriaBrevibacterium linens NCBIZP_00378892

Actinobacteria ActinobacteriaCorynebacterium efficiens NCBIBAC19343

Actinobacteria ActinobacteriaCorynebacterium glutamicum NCBINP_601883

Actinobacteria ActinobacteriaCorynebacterium jeikeiumSwiss-ProtQ4JXL1

Actinobacteria ActinobacteriaMycobacterium avium NCBIAAS02776

Actinobacteria ActinobacteriaMycobacterium tuberculosis NCBIO06284

Actinobacteria ActinobacteriaMycobacterium leprae NCBIP46861

Actinobacteria ActinobacteriaNocardia farcinica NCBIBAD55253

Actinobacteria ActinobacteriaBifidobacterium longum NCBIAAN25440

Actinobacteria ActinobacteriaArthrobacter sp NCBIEAL97549

Actinobacteria ActinobacteriaPropionibacterium acnes NCBIAAT81939

Actinobacteria ActinobacteriaNocardioides sp NCBIEAO06074

Actinobacteria ActinobacteriaThermobifida fusca NCBIZP_00293151

Actinobacteria ActinobacteriaFrankia sp NCBIEAN14067

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Proteobacteria d-proteobacteriaDesulfovibrio desulfuricans NCBIZP_00131094 (80)

Proteobacteria d-proteobacteriaDesulfovibrio vulgaris NCBIAAS96849

Proteobacteria d-proteobacteriaSyntrophobacter fumaroxidans NCBI EAO20646

Proteobacteria d-proteobacteriaDesulfotalea psychrophila NCBICAG36358

Proteobacteria d-proteobacteriaGeobacter sulfurreducensSwiss-ProtQ74AT0

Proteobacteria d-proteobacteriaGeobacter metallireducens NCBIEAM78203

Proteobacteria d-proteobacteriaPelobacter propionicus NCBIEAO35297

Proteobacteria d-proteobacteriaDesulfuromonas acetoxidans NCBIEAM69994

Proteobacteria e-proteobacteriaHelicobacter hepaticus NCBIAAP78263

Proteobacteria e-proteobacteriaHelicobacter pylori NCBIAAD07251

Proteobacteria e-proteobacteriaWolinella succinogenesSwiss-ProtQ7MAR1

Proteobacteria e-proteobacteriaCampylobacter coli NCBIEAL56722

Proteobacteria e-proteobacteriaCampylobacter jejuniSwiss-ProtQ5HW66

Proteobacteria e-proteobacteriaCampylobacter upsaliensis NCBIEAL52475

Proteobacteria e-proteobacteriaCampylobacter lari NCBIEAL54226

Proteobacteria e-proteobacteriaThiomicrospira denitrificans NCBIEAO04113

Proteobacteria unclassifiedUncultured Magnetococcus sp NCBIEAN28803

Proteobacteria g-proteobacteriaXanthomonas oryzae NCBIAAW76126

Proteobacteria g-proteobacteriaXanthomonas axonopodis NCBIAAM36738

Proteobacteria g-proteobacteriaXylella fastidiosaSwiss-ProtQ87EB3

Environmental sampleUncultured bacterium 580 NCBIAAS07872

Proteobacteria b-proteobacteriaNeisseria gonorrhoeae NCBIAAW90095

Proteobacteria b-proteobacteriaNeisseria meningitidesSwiss-ProtQ9JTT7

Proteobacteria b-proteobacteriaChromobacterium violaceumSwiss-ProtQ7NZ62

Proteobacteria b-proteobacteriaAzoarcus sp NCBICAI10033

Proteobacteria b-proteobacteriaDechloromonas aromatica NCBIZP_00151178

Proteobacteria b-proteobacteriaBurkholderia cepacia NCBIZP_00212730

Proteobacteria b-proteobacteriaBurkholderia cenocepacia NCBI EAM12821

Proteobacteria b-proteobacteriaBurkholderia vietnamiensis NCBIEAM29872

Proteobacteria b-proteobacteriaBurkholderia mallei NCBIAAU47811

Proteobacteria b-proteobacteriaBurkholderia fungorum NCBIZP_00283787

Proteobacteria b-proteobacteriaRalstonia eutropha NCBIZP_00170910

Proteobacteria b-proteobacteriaRalstonia metallidurans NCBIEAN53144

Proteobacteria b-proteobacteriaRalstonia solanacearum NCBICAD14730

Proteobacteria b-proteobacteriaPolaromonas sp NCBIEAM41395

Proteobacteria b-proteobacteriaBordetella pertussis NCBICAE41400

Proteobacteria b-proteobacteriaBordetella bronchiseptica NCBICAE32789

Proteobacteria b-proteobacteriaBordetella parapertussis NCBICAE37345

Proteobacteria b-proteobacteriaMethylobacillus flagellatus NCBIEAN03032

Proteobacteria b-proteobacteriaNitrosomonas eutropha NCBIEAO17616

Proteobacteria b-proteobacteriaNitrosomonas europaeaSwiss-ProtQ82SH1

Environmental sampleUncultured bacterium 577 NCBIAAR38056

Proteobacteria b-proteobacteriaThiobacillus denitrificans NCBIZP_00335928

Proteobacteria g-proteobacteriaMethylococcus capsulatus NCBIAAU90453

Proteobacteria g-proteobacteriaIdiomarina loihiensisSwiss-ProtQ5QYV9

Proteobacteria g-proteobacteriaCoxiella burnetii NCBIAAO89981

Proteobacteria g-proteobacteriaLegionella pneumophilaSwiss-ProtQ5WVS0

Proteobacteria g-proteobacteriaFrancisella tularensisSwiss-ProtQ5NI89

Proteobacteria g-proteobacteriaWigglesworthia glossinidia NCBIBAC24587

Proteobacteria g-proteobacteriaBuchnera aphidicola NCBIBAB13135

Proteobacteria g-proteobacteriaCandidatus Blochmannia pennsyl. NCBIAAZ40901

Proteobacteria g-proteobacteriaEscherichia coli NCBICAD66193

Proteobacteria g-proteobacteriaCitrobacter freundii NCBIAAP40013

Proteobacteria g-proteobacteriaShigella flexneriSwiss-ProtQ83JU6

Proteobacteria g-proteobacteriaSalmonella typhiSwiss-ProtQ8Z3X8

Proteobacteria g-proteobacteria E.coli heat/inducedSwiss-ProtQ8FAT5

Proteobacteria g-proteobacteriaYersinia pestisSwiss-ProtQ8ZHK5

Proteobacteria g-proteobacteriaPhotorhabdus luminescensSwiss-ProtQ7N1C8f

Proteobacteria g-proteobacteriaErwinia carotovoraSwiss-ProtQ6D945

Proteobacteria g-proteobacteriaPasteurella multocida NCBIP57822

Proteobacteria g-proteobacteriaHaemophilus somnus NCBIZP_00131887

Proteobacteria g-proteobacteriaHaemophilus influenzae NCBIP43825

Proteobacteria g-proteobacteriaPseudomonas putida NCBIAAN67117

Proteobacteria g-proteobacteriaPseudomonas aeruginosa NCBIZP_00137095

Proteobacteria g-proteobacteriaPseudomonas siringae NCBI AAZ33422

Proteobacteria g-proteobacteriaAzotobacter vinelandii NCBIEAM05680

Proteobacteria g-proteobacteriaPsychrobacter cryohalolentis NCBIEAO10955

Proteobacteria g-proteobacteriaPsychrobacter arcticum NCBIAAZ18906

Proteobacteria g-proteobacteriaAcinetobacter sp NCBICAA86924

Proteobacteria g-proteobacteriaChromohalobacter salexigens NCBIEAM22372

Proteobacteria g-proteobacteriaMicrobulbifer degradans NCBIZP_00315209

Proteobacteria g-proteobacteriaShewanella oneidensis NCBIAAN54065

Proteobacteria g-proteobacteriaShewanella baltica NCBIEAN44386

Proteobacteria g-proteobacteriaShewanella denitrificans NCBIEAN72165

Proteobacteria g-proteobacteriaShewanella frigidimarina NCBIEAN75347

Proteobacteria g-proteobacteriaShewanella amazonensis NCBIEAM57887

Proteobacteria g-proteobacteriaVibrio vulnificus NCBIBAC93433

Proteobacteria g-proteobacteriaVibrio cholerae NCBIAAF93829

Proteobacteria g-proteobacteriaVibrio fischeri NCBIAAW84948

Proteobacteria g-proteobacteriaColwellia psychrerythraea NCBIAAZ26689

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