Second Annual Canvasc Scientific Meeting

Second Annual CanVasc Scientific Meeting

Montreal, Centre Mont-Royal

Thursday, November 22nd 2012

8h30-16h45

Organizing Committee

Drs. Michelle Goulet, Christian Pagnoux, Simon Carette, Nader Khalidi, Christian Pineau

8h30 - Introduction. Drs. Michelle Goulet and Simon Carette

Part 1 – Moderation, Dr. Christian Pagnoux

8h40 - 9h20 Large vessel vasculitides

Clinical updates in LVV - Dr. Nader Khalidi

Objectives:

- Review diagnostic and classification of LVV
- Review the clinical presentation of LVV
- Review role of investigations and biopsy

Updates on LVV treatment – Dr. Patrick Liang

Objectives:

- Review the current guidelines for the treatment of LVV

- Review the recent and potentially future therapeutic developments for LVV

9h20 - 9h50 ANCA testing – how do we know the result is reliable - Dr. Donglai Ma (Euroimmun)

Objectives:

- Basic understanding about ANCA testing

- Most sensitive and specific assays for ANCA testing

- ANCA reporting

9h50 - 10h45 ANCA associated vasculitides

Clinical updates and gold-standard therapy - Dr. Simon Carette

Objectives :

- Summarize current evidence-based management principles for ANCA-related vasculitides

Rituximab and biologics - Dr. Michelle Goulet

Objectives :

- Review the current place and indications of rituximab in the treatment of ANCA-associated vasculitides
- List some of the other biologics with a potential place and/or under investigations in ANCA-associated vasculitides

PLEX and duration of corticosteroids - Dr. Michael Walsh

Objectives :

- Review evidence on PLEX in ANCA-associated vasculitis

- Review the current status of the PEXIVAS trial

- Review current evidence on the optimal corticosteroid therapy duration in ANCA-associated vasculitis

10h45Break

Part 2 – Moderation, Dr. Christian Pineau

11h05 - 12h05 Vasculitis studies in Canada and CanVasc projects

Ongoing CanVasc activities and studies - Dr. Christian Pagnoux

Objectives :

- Review the ongoing CanVasc activities and studies on vasculitis

Opportunities for vasculitis studies in Canada – Dr. Susan Benseler

Objectives :

- Review the ongoing network, activities and studies in Canada in children

- Review how CanVasc activities and studies on adult vasculitis could benefit from collaborations with the pediatric experience and network

Ongoing non-CanVasc studies in Canada - Dr. Christian Pagnoux

Objectives :

- Review the non-CanVasc studies presently ongoing in Canada on vasculitis

12h05 – 13h15 Lunch

Part 3 – Moderation Dr. Nader Khalidi

13h15 - 13h25CanVasc Website - Dr. Christian Pagnoux

Objectives :

- Review the objectives and content of the CanVasc website which may help physicians treating vasculitis patients in their daily practice

13h25 - 13h55Imaging in vasculitides (LVV): PET et MRI - Dr. Ryan Rebello

Objectives :

- To discuss the advantages and disadvantages of various imaging modalities with regards to large vessel vasculitis
- To demonstrate potential implications of MRI in imaging the scalp arteries in suspected GCA
- To discuss the role of imaging in detection and follow-up of aortitis Rebello

Part 4 – Guest Speaker

13h55 - 14h40ANCA- Associated Vasculitis : The Cambridge (U.K.) experience – Dr. Rachel Jones

Objectives :

- Overview of the UK, Cambridge and EUVAS experiences in ANCA-associated vasculitis (from routine daily practice to international studies)

- To review the current evidence on rituximab for ANCA-associated vasculitis based on the Cambridge and UK experience and studies

14h40Break

Part 5 - Moderation Dr. Simon Carette

15h - 15h45 CNS vasculitis

- Pediatric CNS vasculitis and BrainWorks – Dr. Susan Benseler

Objectives :

- Review the principles of the ongoing BrainWorks network and studies in Canada in children with CNS vasculitis and inflammatory brain diseases

- Review how CanVasc activities and studies on adult CNS vasculitis could benefit from collaborations with the pediatric BrainWorks experience

- Adult CNS vasculitis and InterSpace – Dr. Sylvain Lanthier

Objectives :

- Review the aims and principles of the ongoing InterSpace study on CNS vasculitis

- Review how CanVasc and BrainWorks studies could cooperate and benefit from collaborations with the InterSpace study

Part 6 – Moderation Dr. S. Brachemi

15h45-16h45 Meet the Expert : difficult vasculitis cases. Panel of CANCAS core members

Objectives :

- Discuss about several difficult vasculitis cases and identify the different therapeutic options

16h45 Conclusion Drs. Michelle Goulet and Christian Pagnoux

The meeting is held with unrestricted educational funding supports from the following pharmaceutical companies

Platinum funding support

Silver funding support