Rapid Sequence

Intubation Regional

Guidelines

OLD DOMINION

Emergency Medical Services

ALLIANCE

Current January 2006

Regional Guidelines and Related Information

For Agencies Planning RSI Programs

In Planning Districts 13, 14, 15 and 19,

Old Dominion EMS Alliance Inc.

1463 Johnston-Willis Drive

Richmond, Virginia23235-4730

Phone: 804-560-3300

Fax: 804-560-0909

Preface

TheseRegional Rapid Sequence Intubation Guidelines were approved by the Old Dominion EMS Alliance (ODEMSA) Medical Control Committee,and were implemented in November 2005. They are intended to provide guidance to those advanced life support (ALS) agencies in the ODEMSA region that are considering initiating a rapid sequent intubation airway management program under the direction of its operational medical director (OMD). In publishing these guidelines, the Medical Control Committee recognizes the need for alternate modes of airway management and the fact that ALS agencies must adapt some procedures to meet unique local needs and requirements.

Therefore, these are minimal guidelines. The guidelines and related documents are designed to provide a template by which agencies in the ODEMSA region will be able to meet a regional standard of care while meeting those local needs and requirements. The agency OMD is welcome to enhance a rapid sequence intubation (RSI) program. Please note, however, that whatever RSI program the agency and its OMD develop must contain at a minimum all of the elements in these guidelines in order to meet the regional standard of care as established by the ODEMSA Medical Control Committee.

Arthur C. Ernst, M.D., FACEP

ODEMSA Medical Director

Appreciation

These guidelines are the result of the combined efforts of three major EMS agencies and a major teaching college in the Old Dominion EMS Alliance region. The primary document has been modified from the RSI protocol created by the Henrico County Division of Fire at the direction of the Old Dominion EMS Alliance Medical Control Committee. The Regional RSI Training Guidelines are based on those developed by Hanover County Fire and EMS. Other elements and templates have come from those developed by Chesterfield County Fire and EMS and several hospital emergency physicians. ODEMSA and its member EMS agencies are indebted to these agencies, their chiefs, and individuals who have contributed their time and expertise to developing and/or reviewing this document. These include:

Henrico County Division of Fire:

Chief Ronald Mastin, Chief of the Division

Robert G. Powell, M.D., FACEP, Operational Medical Director

R.D. McClure, NREMT-P, Assistant Chief

Kelly P. Schaaf, R.N. Quality Assurance Coordinator

Hanover County Fire and EMS:

Chief Fred G. Crosby, NREMT-P, Chief of Department

Randy P. Abernathy, NREMT-P, Deputy Chief

Jethro Piland, NREMT-P, Division Chief

Michael Watkins, NREMT-P, Training Officer

Chesterfield County Fire and EMS:

Chief Paul Mauger, Chief of Department Allen Yee, M.D., FACEP, Operational Medical Director

John M. Kirtley Jr. NREMT-P, EMS/ALS Training Officer

John C. Greene, NREMT-P, EMS Med-Flight 1

VCU MedicalCenter:

Joseph P. Ornato, M.D., FACEP, Chair,

Emergency Medicine Department.

S. Rutherfoord Rose, Pharm.D., Director, VirginiaPoisonCenter

Harinda Dhindsa, M.D., Medical Director, VCU LifeEvac

James H. Gould Jr., R.N., NREMT-P, Director, CT&CCE

Regional Rapid Sequence Intubation Guidelines

Current January 2006

Contents

Section 1

RSI Regional Program Guidelines

Section 2

RegionalRSI Training Guidelines

Section 3

A.Suggested RSI Program Elements

B.Recommended Medication-Facilitated Intubation Protocol

Section 4

Regional RSI Drug Box Contents

Section 5

A.Regional QA/QI Guidelines for RSI

  1. Recommended RSI Evaluation Form

C.Glossary/Definitions

Rapid Sequence Intubation (RSI)

Section 1

Regional Program Guidelines

Planning Districts 13, 14, 15 and 19

Current January 2006

Scope:

These guidelines are intended for use only in circumstances/situations approved by an EMS agency operational medical director (OMD) in a program endorsed by the Old Dominion EMS Alliance’s (ODEMSA) Medical Control Committee. The guidelines are designed to allow trained and cleared EMS providers the option of managing patient airways with Rapid Sequence Intubation (RSI) in the ODEMSA region. This document and related information will provide clear guidelines to trained EMS providers about patient care requiring RSI, proper documentation, and the essential quality assurance/quality improvement (QA/QI) review.

NOTE:RSI in the ODEMSA region will be performed only when there are at least two (2) ALS providers cleared for intubation on the scene during the RSI procedure. One of these providers must be an EMT- Paramedic cleared for RSI. The ability to perform RSI in the ODEMSA region will be restricted to the EMT-Paramedic level of certification.

These regional guidelines will apply to any patient that meets the patient profile in Section IV of these guidelines.

  1. Definition:

Rapid Sequence Intubation, or RSI, is the use of pharmacological agents to facilitate endotracheal intubation. Rapid sedation and paralysis using neuromuscular blocking agents allows laryngoscopy and placement of an endotracheal tube in those patients who fulfill the patient profile requirements.

  1. Purpose:

RSI is an organized approach to emergency intubation comprising rapid sedation and muscle paralysis. Pharmacological paralysis facilitates endotracheal intubation and maximizes the probability of successful placement of an endotracheal tube while minimizing hemodynamic responses and complications.

NOTE: Neuromuscular blocking agents will not be given without first giving a sedative agent to the patient!

A general overview of RSI involves: assessment of the patient; pre-oxygenation; preparation of equipment and medications; sedation; cricoid pressure; muscle relaxation; intubation; securing the airway; continuous reassessment; delivery of the patient to the most appropriate medical facility; and completion of the quality assessment/quality improvement (QA/QI) process.

  1. Patient Profile:

The standard of airway control is orotracheal intubation using RSI as indicated for the following patients:

  1. Airway protection from hemorrhage, aspiration, edema, hematoma.
  1. Airway protection for the unresponsive patient who may not be intubated using standard airway management techniques. This altered level of consciousness may be from injury, multiple trauma, burns, ingestion of excessive medications, stroke, or infection.
  1. Impending cardiac arrest due to respiratory fatigue and/or failure. This may be

due to uncontrolled seizure activity, status asthmaticus, overdose, circulatory

shock secondary to trauma or infection, or combative patient.

  1. Failure to appropriately ventilate/oxygenate a patient with other conservative resources.
  1. Any patient who demonstrates a decreasing ability to self-ventilate or self-oxygenate during the initial assessment or subsequent reassessment(s).
  1. Patient Exclusion Criteria:
  1. Any patient under age 14 and/or weighing less than 45 kgs.
  1. Any patient who has spontaneous respirations with adequate ventilation/oxygenation and a protected airway.
  1. Any patient where intubation may not be successful due to airway obstruction or trauma (i.e. epiglottitis, major facial/laryngeal trauma with significant edema or distortion of facial/airway anatomy).
  1. Upper airway obstruction.
  1. Any patient with known hypersensitivity to RSI drugs.

V.Relative Contraindications:

1.Any patient with known hyperkalemia.

  1. Any patient with penetrating eye injuries.
  1. Any patient with a history of malignant hyperthermia.
  1. Any patient with myasthenia gravis.

VI. Recognized Potential RSI Complications:

  1. Inability to secure the airway after paralytic administration.
  1. Dysrhythmias.
  1. Aspiration.
  1. Tachycardia.
  1. Bronchospasm.
  1. Increased intracranial pressure.
  1. Inability to recognize decreased neurological status.
  1. Hypoxia.
  1. Cardiac arrest.
  1. EMS Provider Profile:

Initial:EMS providers who meet the following criteria will be cleared to perform RSI:

  1. EMT-Paramedic certification with documented one (1) year of experience as a cleared advanced life support (ALS) provider.

2.Three (3) documented successful live intubations within the last year, or special clearance by the agency OMD after personal observations of airway management techniques in the lab or OR/ED.

3.Completion of a training program that incorporates all elements of these Regional RSI Guidelines and is endorsed by the ODEMSA Medical Control Committee.

4.A passing score on a regional written test administered during the training program, as well as satisfactory completion of the RSI clinical lab instruction and testing.

  1. A RSI authorization form signed by the provider’s OMD, maintained by the agency’s quality assurance coordinator, and updated every 12 months.

Recertification: Successful completion of a recertification program, which includes both didactic and practical components to the process (approximate four (4) hour course). This program requires special training, extra care in documentation and participation in QA/QI, ongoing training, and the OMD’s specific approval of each EMT-Paramedic participating.

NOTE: Approval to perform RSI may be rescinded by the agency OMD at any time based solely on the judgment of the OMD. This decision will be based upon the provider’s decision-making ability, documentation, quality assurance reports, etc.

VIII. Regional RSI Medications

Medications approved by the ODEMSA Medical Control Committee for use in Rapid Sequence Intubation procedures within the ODEMSA region are: etomidate, lidocaine, succinylcholine, vecuronium and versed.

NOTE: Rocuronium will be used in a pilot program conducted by the three air medical services in the ODEMSA region. It will not be stocked at this time in the Regional RSI Drug Box.

A standard marked Regional RSI Drug Box (Pelican #1150) will be available at cost to agencies whose providers are approved to perform RSI. Requests for these drug boxes will follow the procedure listed in Section 6 of the region’s ALS Drug Box Policies and Procedures. Regional RSI Drug Boxes must be maintained, checked and stored in compliance with the rules and regulations of the Virginia Board of Pharmacy and the Virginia Department of Health’s Office of Emergency Medical Services, and the region’s ALS Drug Box Policies and Procedures.

Agencies are encouraged to use the standard Regional RSI Drug Box. Agencies that chose to maintain their own boxes must include in those boxes all of the medications and support items in the same concentrations and measures as listed in the Regional RSI Drug Box Contents (see Section 4 of this document).

  1. Regional RSI training program:

The Regional RSI training program will consist of, but will not limited to:

1.Enhanced Airway Management

  1. Airway anatomy and physiology.
  2. Basic airway procedures.
  3. Advanced airway procedures.
  4. Scenario training.
  5. Difficult airway management.
  1. Rapid Sequence Intubation Training
  1. Advanced anatomy and physiology.
  2. Difficult airway predictors.
  3. Pediatric airway problems.
  4. Basic airway review.
  5. Advanced airway review.
  6. RSI procedure.
  7. Difficult airway management.
  8. RSI Pharmacology.
  9. Special RSI considerations.
  10. RSI skills training with scenarios.
  11. Written RSI assessment.

Note: Training will include appropriate elements for pediatric RSI. At this time, these regional Guidelines restrict RSI to patients who are over 14 years of age and who weigh more than 45 kgs.

  1. Additional Elements:

a.Practice scenarios with demonstration of adequate skill with intubation in a variety of circumstances.

  1. Written test and practical examination.
  2. Patient profile discussion for successful RSI and contraindications.
  3. A discussion of the circumstances as to when not to attempt RSI on a patient (patient exclusion criteria).
  4. Alternative methods to secure an airway (Combitube, oral and nasal intubation, etc.), with emphasis on the provider defining alternative airway management modalities for specific patients prior to the RSI attempt, and having those modalities ready in the event of RSI failure.
  5. Agency policy and regional protocol review.
  6. Mandatory quality assurance/quality improvement (QA/QI.
  1. General Guidelines:

The following are an overview of General Policy Guidelines – see attached regional protocols for performance of RSI.

1.Preparation

a.Take into consideration the indications, risks and alternatives to RSI.

  1. Obtain AMPLE history.

c.Perform a brief anatomic assessment.A thorough evaluation of the anatomy of the hypopharynx is essential in airway management. Perform an anatomic assessment to determine those patients who are to be considered as RSI candidates, and those airway alternatives that may be required with failed RSI.

d.Perform a brief neurological assessment.

Document neurological status and GCS Score. This must precedethe administration of sedatives and paralytic agents.

d.Essential equipment.

1)Suction (working with Yankauers attached)

2)Oxygen (connected to a BVM)

3)Airway (laryngoscope, ET tube, stylet, BVM – failed RSI back up alternate airway adjuncts, Combitube and surgical cric equipment, etc.)

4)Pharmacology - have all required drugs that are expected to be used in an easily accessible and premixed condition. These agents must be readily available upon demand when attempting RSI.

5)Monitoring equipment (cardiac monitor, pulse ox, ETCO2 monitor, and BP monitor).

  1. Establish an open airway and pre-oxygenate

Pre-oxygenation is required before proceeding with sedation and paralysis. If at all possible, allow the patient to pre-oxygenate on his or her own. Patients should be given 100 percent oxygen via non-rebreather facemask while assembling equipment (approximately four to five (4-5) minutes), or assist the patient’s own effort with a BVM and 100 percent oxygen for one to two (1-2) minutes to maximize oxygen saturation.

Note: BVM assist increases potential for gastric distention with air, which increases the possibility of vomiting and aspiration.

3.Place patient on continuous cardiac monitor, pulse oximeter, and continuous blood pressure monitoring.

4.Verify that functioning IV line is securely in place.

5.Premedication if indicated.

Lidocaine– Use for any patient with suspected head injury to manage increased intracranial pressure. Lidocaine has been shown to blunt the cardiovascular response to the stimulation of the airway. Lidocaine decreases the likelihood of tachycardia and hypertension. Lidocaine decreases intracranial and intraocular pressure that can be associated with RSI.

Usual Dose: 1.0 – 2.0 mg/kg IV 2-5 minutes prior to laryngoscopy

(Maximum dose 150mg. Maximum efficiency is 3-5 minutes after dosing).

Contraindications: Heart block, severe hypovolemia, bradycardia and CHF.

Atropine (not carried in Regional RSI Drug Box) – Consider Atropine for any patient with bradycardia prior to intubation.

Usual Dose: 0.01 mg/kg IV.

Contraindications: Third (3rd) degree heart block. Atropine may exacerbate ischemia or induce VT or VF when used to treat bradycardia associated with AMI.

  1. Sedation

NOTE: Sedatives must be administered prior to administration of a neuromuscular blocking agent, to eliminate the sensation of paralysis.

Etomidate:An anxiolytic sedative and hypnotic agent with an onset of action of 30 seconds and a duration of action of from five (5) to 10 minutes. It is well suited as an induction agent for RSI because its pharmacokinetic profile closely matches that of succinylcholine and it has minimal cardiovascular side effects. The transient suppression of cortisol synthesis is of no clinical significance with a single dose.

Usual Dose: 0.3 mg/kg. Consider dose reduction in the elderly because of age-related differences in kinetic parameters and increased risk for cardiac depression in older hypertensive patients.

Contraindications: Adrenal insufficiency, hypersensitivity to entomidate.

Side Effects: Clinically significant adrenal dysfunction has been seen with long-term use of etomidate.

Versed: A safe, short-acting benzodiazepine with a slightly longer duration (30-60 minutes). Re-dosing is therefore less likely. There is also a remarkable amnesic quality to Versed that is of great importance with the successful completion of this skill and patient satisfaction.

Usual Dose: 2-5 mgs IV push. (based on dosing of .05mg/kg). Versed should be administered two (2) full minutes before intubation is attempted.

Re-dosing: 2-5 mgs IV push may be repeated in 6-10 minutes after initial dose. Additional sedation may be needed to control tube placement, intracranial pressure and vital signs. Re-dosing may be administered to patients who are agitated, arouseable and aware of their surroundings to reduce the fear and stress related to the intubation.

NOTE: A significant number of patients may be intubated with the use of sedation without paralytic agents.

NOTE: PARALYTICS ARE NOT INDICATED IF A PATIENT MAY BE ADEQUATELY AND SAFELY INTUBATED AFTER THE SOLE ADMINISTRATION OF VERSED.

Hypotension related to versed administration may be reversed with IV fluid bolus.

  1. Cricoid Pressure (Sellick Maneuver)

While cricoid pressure may help with visualization, the procedure is not intended for facilitating visualization of the cords. The purpose of cricoid pressure during intubation is to decrease the chance of regurgitation with subsequent aspiration by pressing the cricoid cartilage firmly against the esophagus. Cricoid pressure is applied after sedation and is not released until after intubation, cuff inflation and verification of ET tube placement. If pressure is released prior to inflation of the balloon, the esophagus opens and exposes the patient to possible aspiration.

Attempting Sellick’s on a person with intact airway reflexes (i.e. not sedated or obtunded) may precipitate coughing or vomiting. If the patient begins to vomit, release cricoid pressure while turning patient onto side to protect the airway from aspiration. Suction as needed. Continued cricoid pressure during an episode of vomiting can result in iatrogenic rupture of the esophagus.

NOTE: The Sellick Maneuver has also been reported to cause airway obstruction because of excessive force occluding the trachea.

8.Administration of a Neuromuscular Blocking Agent

Succinylcholine:An ultra-short-acting depolarizing –type skeletal muscle relaxant. It is well-suited for RSI but does have some potentially life-threatening side effects in certain patient populations. Succinylcholine has an onset of action of 45 seconds with an initial dose. It has a duration of action of from five (5) to 10 minutes.

Usual Dose:1.5 mg/kg, may repeat in two (2) to three (3) minutes to achieve paralysis (2 mg/kg in children, 3 mg/kg in infants).