Curriculum vitae
PERSONAL INFORMATION
Name: Camilla Sjögren
Nationality: Sweden
Date of birth: 1963-12-17
URL for web site: http://ki.se/en/cmb/camilla-sjogrens-group
· EDUCATION
1997 PhD in Natural Sciences, Department of Cell Biology, Wenner-Gren Institute, Stockholm University, Sweden
1990 Master degree in Natural Sciences, Department of Cell Biology, Wenner-Gren Institute, Stockholm University, Sweden
· CURRENT POSITION(S)
2010 – present Professor in cell and tumour biology, Dept. of Cell and Molecular Biology, Karolinska Institutet, Sweden
2002 – present Group leader and Principal Inv. Dept. of Cell and Molecular Biology, Karolinska Insitutet, Sweden
· PREVIOUS POSITIONS
2001 – 2002 Guest researcher, Södertörn University College, Stockholm, Sweden
1999 – 2001 Post doctor, K. Nasmyth’s group, Research Institute for Molecular Pathology (IMP), Vienna, Austria.
· FELLOWSHIPS AND AWARDS
2014 Nicholson lecturer at Rockefeller University, NY, USA
2008 European Research Council (ERC) Starting Grant
2008 Fernströms prize to young researchers
2007 Royal Swedish Academy of Sciences Research Fellow in Medical sciences
2002 Junior research position grant, Swedish Research Council
1998 Postdoctoral fellowship by The Swedish Foundation for International Cooperation in Research and Higher Education (STINT)
· SUPERVISION OF GRADUATE STUDENTS AND POSTDOCTORAL FELLOWS
2002 – present
Main Supervisor of 5 post doctors and 5 PhD- and 1 Licentiate student
Past PhD students
Ingrid Lilienthal, PhD 2014
Hanna Lindroos, PhD 2009
Charlotte Karlsson, Licentiate 2009
Past Post doctors
Dr Lena Ström, 2002 – 2007, junior PI grant in 2007, senior research position in 2011.
Dr Andreas Kegel, 2006-2011, junior PI grant in 2011.
Dr Maartje Brink, 2009-2011
· TEACHING ACTIVITIES
2002-present
Lecturer in cell biology for undergraduate students at Karolinska Institutet
Invited lecturer to advanced/master courses in Cell Biology at Karolinska Institutet, Stockholm University and Södertörn University College.
Faculty opponent, thesis defence by K Mundbjerg, University of Aarhus, Denmark, 2011
Evaluation committee member at 10 PhD-, and 2 Licentiate defences at Stockholm University and Karolinska Institutet
Supervision of 18 undergraduate students in long term (>3 months) projects
2007-2012 Organiser of biannual PhD course in Genome Integrity at Karolinska Institutet
2001-2002 Main responsible undergraduate 10 week course in Cell Biology at Södertörn University
College
· ORGANISATION OF SCIENTIFIC MEETINGS
2011 and 2013, Organiser of Abcam conferences “Chromatin Replication and Chromosomal stability” in Stockholm and Copenhagen
2003 Coordinator of Nobel conference, “Chromosome segregation and human disease“, Stockholm
· INSTITUTIONAL RESPONSIBILITIES
2012-present Faculty representative at the Karolinska Institutet’s Board of Research
2005-present Vice chairman, Dept. of Cell and Molecular Biology, Karolinska Insitutet
2008-2011 Board member, Swedish society for Biochemistry and Molecular Biology (SFBBM)
· COMMISSIONS OF TRUST
2009-2014 Member of Swedish Cancer Foundation project grant evaluation panel, panel vice chair 2011-2012, chair 2013-2014.
2009-2012 Member of starting grant evaluation panel, European Research Council, panel vice chair 2011-2012.
2008 Member of evaluation panel, Swedish Research Council. Project grant applications.
2002-present Evaluator of candidates for EMBO fellowships, two professorships at University of Copenhagen, and two Wellcome Trust grant applications. Guest Editor for Experimental Cell Research, special issue on DNA repair, http://www.sciencedirect.com/science/article/pii/S0014482714004340, Reviewer of manuscripts submitted to Science, EMBO reports, EMBO Journal, Molecular Cell, Current Biology, Genes and Development, Nucleic Acid Research, Journal of Clinical Investigation, and more
· MEMBERSHIPS OF SCIENTIFIC SOCIETIES
2013 Swedish Royal Academy of Sciences, Class of Medical Sciences
2013-present Adjunct member of the Nobel committee, prize in medicine of physiology
2012 The Nobel Assembly at Karolinska Institutet
2009 National committee for Molecular Bioscience, Swedish Royal Swedish Academy of Sciences
2008 European Molecular Biology Organization (EMBO)
· MAJOR COLLABORATIONS
K. Shirahige, ChIP analysis of chromosome association, Tokyo University, Japan, http://www.iam.u-tokyo.ac.jp/chromosomeinformatics/
A. Göndör, chromosome conformation capture analysis, Karolinska Institutet, Sweden, http://ki.se/en/mtc/anita-gondor-group
H. Schüler, protein structure analysis, Karolinska Institutet, Sweden, http://psf.ki.se/PARP/index.html
CAREER BREAKS: Three children born 1996, 1998 and 2001
TRACK RECORD
TEN REPRESENTATIVE PUBLICATIONS
1. Jeppsson K., Carlborg K., Nakato R., Berta D., Lilienthal I., Kanno T., Lindqvist A., Brink M., Dantuma N., Katou Y., Shirahige K., Sjögren C. The Chromosomal Association of the Smc5/6 Complex Depends on Cohesion and Predicts the Level of Sister Chromatid Entanglement. PLOS Genet Research Article, October 16, 2014.
2. Jeppsson K., Kanno T., Shirahige K., and Sjögren C. The maintenance of chromosome structure: positioning and function of SMC complexes. Invited review, Nat. Rev. Mol. Cell Biol. 2014; 15; 601-14
3. Lilienthal I, Kanno T, Sjögren C. Inhibition of the Smc5/6 complex during meiosis perturbs joint molecule formation and resolution without significantly changing crossover or non-crossover levels. PLOS Genet. 2013; 9(11): e1003898. doi: 10.1371/journal.pgen.1003898.
4. Carter Dewey S. and Sjögren C. The SMC complexes, DNA and chromosome topology –right or knot? Invited review. Crit. Rev. Biochem. Mol. Biol. 2012; 47;1-16
5. Kegel A., Betts-Lindroos H., Kanno K., Jeppsson K., Ström L.,Katou Y., Itoh T., Shirahige S., Sjögren C. Chromosome length influences replication-induced topological stress. Nature, 2011; 471; 392-396.
Comments on the investigation: Comment: Branzei D., “The three SMC sisters”, Nat. Rev. Mol. Cell Biol. 2011; 6;
6. Kegel A. and Sjögren C. The Smc5/6 complex – more than repair? Cold Spring Harb Symp Quant Biol. 2010;75:179-87. Invited contribution
7. Ström L., Karlsson C., Betts Lindroos H., Wedahl S., Katou Y., Shirahige K., Sjögren C. Post-replicative formation of cohesion is required for repair and induced by a single DNA break. Science, 2007; 317; 242-245.
Comments on the investigation:
Perspective: Watrin E and Peters J-M, “How and when the genome sticks together”, Science, 2007; 317; 209-210.
Research highlights: “Stuck back together”, Nature, 2007; 448; 229. “Damage takes control”, Nature Review Genetics, 2007; 08; 652-653.
Faculty of 1000 Biology: evaluations for Ström L et al Science 2007 Jul 13317 (5835):242-5 http://www.f1000biology.com/article/id/1090513/evaluation
Dispatch: Ball A., and Yokomori K., “Damage-induced reactivation of cohesin in postreplicative DNA repair”. Bioessays, 2008; 01; 5-9.
8. Ström L. and Sjögren C. Chromosome segregation and DSB repair – a Complex Connection. Invited Review. Curr. Op. Cell Biol. 2007; 19; 344-349.
9. Betts Lindroos H., Ström. L., Itoh T., Katou, Y., Shirahige K., and Sjögren C. Chromosomal association of the Smc5/6 complex reveals that it functions in differently regulated pathways. Mol. Cell, 2006; 22; 755- 767.
10. Ström L., Betts Lindroos H., Shirahige K., Sjögren, C., Postreplicative recruitment of Cohesin to double-strand breaks is required for DNA repair. Mol. Cell, 2004; 16; 1003-1015.
Comments on the investigation:
News and views; Hirano T., “Holding sisters for repair”. Nature 2005; 433, 467 – 468.
Dispatch; Lowndes N., and Toh G., “DNA repair: the importance of phosphorylating histone H2AX”, Current Biology 2005; 15, R99-R102.
Faculty of 1000 Biology: evaluations for Ström L et al Mol Cell 2004 Dec 22 16 (6):1003-15 http://www.f1000biology.com/article/id/1023044/evaluation
INVITED SPEAKER TO INTERNATIONAL CONFERENCES (since 2007)
31 international conferences, e.g. EMBO-, FASEB-, Keystone-, Gordon- , replication Repcombination repair, FEBS-, EMBO and Cold Spring Harbour-conferences
Session chair at FEBS, EMBO and Gordon meetings.
EMBO supported keynote lecturer twice:
FASEB meeting "Yeast Chromosome Structure, Replication & Segregation”, Steamboat Springs, USA 2012
International University of Andalusia meeting “RNA meets DNA”, Baeza, Spain, 2014
INVITED RESEARCH SEMINARS (since 2007)
31 research lectures, e.g. Spanish National Cancer Research centre (Madrid), Clare Hall Laboratories (twice), Imperial College and London Research Institute (London), Grey Institute (Oxford, twice), Rockefeller University, Sloan-Kettering Cancer Center (New York), Max-Planck Institute (Martinsried), Curie Institute and Institute Jacques Monod (Paris), Tokyo and Kyoto Universities, Umeå-, Lunds-, Uppsala- and Göteborg- Universities.
ORGANISATION OF INTERNATIONAL CONFERENCES
2011 and 2013, Organiser of Abcam conferences “Chromatin Replication and Chromosomal stability” in Stockholm and Copenhagen
2003 Coordinator of Nobel conference, “Chromosome segregation and human disease“, Stockholm
INTERNATIONAL PRIZES/AWARDS/ACADEMY MEMBERSHIPS
2013, 2014 Adjunct member of The Nobel committee, prize in medicine of physiology
2014 Nicholson lecturer at Rockefeller University, NY, USA
2013 Member of Swedish Royal Academy of Sciences, Class of Medical Sciences
2012 Member of The Nobel Assembly at Karolinska Institutet
2008 European Molecular Biology Organization (EMBO)
2008 European Research Council (ERC) Starting Grant