Mohsin M. Syed, Ph.D
Department of Neurobiology and Developmental Sciences
University of Arkansas for Medical Sciences College of Medicine
4301 W. Markham, Slot 846 Little Rock, AR 72205
Phone: (501) 526-7885 FAX: (501) 526-6756
Email:
Education:
Ph. D in PhysiologyNagoya University, Japan1993
(Evaluated by World education services, NY, USA as equivalent to PhD in USA)
Bachelor of Science (Honors)Dhaka University1985
Major- Physiology with BiochemistryBangladesh
Minor-Anatomy & Pharmacology
Research Interests:
• Study of the role of proinflamammatory mediators IL-1, TNF- on connexin
expression and the functional importance of Cx43 (Gap junction protein) in
disease pathogenesis in a mouse model of Staphyllococus aureus- induced
experimental brain abscess.
• Gap junction communication in glial cells and effect of bacteria and bacterial cell
wall products in modulating gap junction communication in normal and
genitically manipulated animals.
• Toll Like receptor 2 (TLR2) expression in astrocyte and microglia, effect of
cytokines in TLR2 expression. Signal transduction and various signaling
pathways specially NF-kB pathway
• Activity dependent developmental changes in the mammalian retina, focusing
mainly on the generation, mechanism, dynamics and function of the spontaneous
Ca2+ waves in development and refinement of visual system.
Teaching Experience:
•Currently teaching (2005- till date) Gross anatomy, Microanatomy and
Neuroscience to the Medical School students at The University of Arkansas for
Medical Sciences (UAMS)
• 2 years of teaching (2003-2005) Human Anatomy & Physiology at The
University of Arkansas, Pine Bluff (UAPB).
• 7 years experience (1993-2000) in teaching Human Physiology & to Medical
School students. Which include General Physiology, Blood & Cardiovascular
system, Respiratory system, Gastrointestinal anatomy and physiology, Urinary
system and body fluids, Neurophysiology, Endocrinology and Reproductive
system.
Academic Positions:
February 2007 till date
Instructor, Department of Neurobiology & developmental Sciences, UAMS
August 2004-January 2007
Research associate, Department of Neurobiology & developmental Sciences, UAMS
February 2001-July. 2004
Research Associate, Department of Physiology & Biophysics, UAMS
August 1999-January 2001
Associate Professor of Physiology, Dhaka National Medical College, Dhaka,
Bangladesh.
October 1996-July 1999
Associate Professor of Physiology, The Medical College for Women, Dhaka,
Bangladesh
May 1993-September 1996
Assistant Professor of Physiology, The Medical College for Women, Dhaka,
Bangladesh.
Awards & other professional activities;
2002Travel grant to attend FASEB meeting (Retinal neurobiology) in Saxtons
River, Vermont
2000Awarded scholarship by the Association of International Education Japan
for Post doctoral research.
1997-2000 Education advisor, Embassy of Japan, Dhaka, Bangladesh
1987Scholarship from the Ministry of education (Monbusho), Japan for PhD
program.
Publications:
1. Mohsin Md. Syed, Nirmal K. Phulwani, and Tammy Kielian
Tumor necrosis factor-alpha (TNF-cc) regulates Toll-like receptor 2 (TLR2)
expression in microglia.
Journal of Neurochemistry 2007- In the press.
2. Tammy Kielian, Nilufer Esen, Shuliang Liu, Nirmal K. Phulwani, Mohsin Md. Syed, Koren Nishina, Ambrose L. Cheung, Joseph D. Schwartzman, and Jorg J. Ruhe
Minocycline Modulates Neuroinflammation Independently of Its Antimicrobial Activity in Staphylococcus aureus-Induced Brain Abscess. American Journal of Pathology, 2007-In the press
3.Tammy Kielian, Nirmal K. Phulwani, Nilufer Esen, Mohsin Md. Syed, Haney, A.
C. McCastlain, K.
MyD88-dependent signals are essential for the host immune response in
experimental brain abscess
J. Immunology 2007, 178: 4528-37
4.Nilufer Esen, Debbie Shuffield, Mohsin Md. Syed, and Tammy Kielian
Modulation of connexin expression and gap junction communication in astrocytes
by the gram-positive bacterium S. aureus
Glia 2007, 55: 104-117
5. Sarita Garg, Mohsin Md. Syed and Tammy Kielian
Staphylococcus aureus-derived peptidiglycan induce Cx43 epression and
functional gap junction intercellular communication in microglia.
Journal of Neurochemistry 2005, 95, 475-485
6. Mohsin Md. Syed, Seunghoon Lee, Shigang He and Z. Jimmy Zhou
Spontaneous waves in the ventricular zone of developing mammalian retina.
Journal of Neurophysiology- 91 (2004) pp: 1999-2004
7. Mohsin Md. Syed, Seunghoon Lee, Jijian Zheng and Z. Jimmy Zhou
Stage-dependent dynamics and modulation of spontaneous waves in the
developing rabbit retina.
J. Physiol 560.2 (2004) pp 533-549
8.Mohsin Md. Syed, Anant B. Parekh & Tadao Tomita.
Receptors involved in mechanical responses to catecholamines in the circular muscle of Guinea-Pig stomach treated with meclofenamate. Br. J. Pharmacol, 101, 809-814(1990)
9. Mohsin Md. Syed, Hiroyuki Tokuno and Tadao Tomita. Effects of Cisapride on isolated Guinea-Pig colon. Japan J. Pharmacol. 51, 47-56 (1989)
Book Chapter:
1T. Tomita and Mohsin Md. Syed.
Catecholamine action on pyloric sphincter.
In Sphincter : Normal function and changes in diseases. E. E. Daniel, T. Tomita, S. Tsuchida, M. Watanabe Eds. (CRC press, florida, 1992) pp. 117-129
2Tadao Tomita, Hiroyuki Tokuno, Mitsuaki Ito, Mohsin Md. Syed & Toshiharu
Matsumoto.
Effects of ammonium on vascular smooth muscle.
In Ion channels of vascular smooth muscle cells and endothelial cells.
N. Sperelakis and H. Kuriyama Eds. (Elsevier, New York 1991) pp. 217-223