Jordan University of Science and Technology

Faculty of Pharmacy

Department of Medicinal Chemistry and Pharmacognosy

First Semester 2008/2009

Course Syllabus

Course Information
Course Title / Pharmaceutical Organic Chemistry 1
Course Code / Phar 221
Prerequisites / General Chemistry (Chem 103)
Instructor / Prof. Mohammad Hassan
Office Location / P1 Level 1
Office Phone / 72010 00 Ext. 23539
Office Hours / 9:15 – 10:15 S T Th, 10:15-11:15 M
E-mail /
Text Book
Title / Organic Chemistry
Author(s) / John McMurry
Publisher / Thomson-Brooks/Cole
Year / 2008
Edition / 7th
References / Advanced Organic Chemistry by Michael Smith and Jerry March, 5th Edition , Wiley 2000.
Assessment
Assessment Type / Expected Due Date / Weight
First Exam / 25/10/2008 / 30%
Second Exam / 29/11/2008 / 30%
Final Exam / TBA / 40%
Teaching & Learning Methods
1. Class lectures and lecture notes are designed to achieve the course objectives.
2. You should read the assigned chapters before class and participate in class and do whatever it takes for you to grasp this material. Ask questions. Ask lots of questions.
3. You are responsible for all material covered in the class.
Learning Outcomes: Upon successful completion of this course, students will be able to
1. Learn the fundamentals of organic chemistry
2. Be able to assign proper names and / or stereochemistry to organic molecules
3. Learn the chemistry aliphatic, alicyclic and olefinic hydrocarbons
4. Learn the mechanisms and applications of SN1, SN2, E1 and E2 reactions.
Course Content
Week / Topics / Chapter in Text
1 / 1. Structure and Bonding of Organic Compounds / 1-2
a. Atoms and Molecules
b. Bonding forces
2 / c. Hybridization
d. Structures and Formulas of Organic Compounds
3-5 / 2. Alkanes and Cycloalkane / 3,4
a. Properties
b. Nomenclature
c. Reactions
d. Stereochemistry (Conformational Isomers)
6 / 3. Overview of Organic Reactions / 5
7-10 / 4. Alkenes / 6-7
a. Properties
b. Nomenclature
c. Preparation and Reactions
11 / 5. Alkynes / 8
a. Properties
b. Nomenclature
c. Preparation and Reactions
12-13 / 6. Stereochemistry
a. Enantiomers and Chirality / 9
b. Specifying configuration (R&S)
c. Diastereomers and meso compounds
d. Stereochemistry of Reactions
14 / 7. Alkyl halides / 10
a. Properties
b. Nomenclature
c. Preparation
d. Reactions
Additional Notes
Exams / ·  The format for the exams is generally (but NOT always) as follows: Multiple-choice and short essay questions.
Cheating / The commitment of the acts of cheating and deceit such as copying during examinations, altering examinations for re-grade, plagiarism of homework assignments, and in any way representing the work of others as your own is dishonest and will not be tolerated. Standard JUST policy will be applied
المادة 7: إذا ضُبط الطالب أثناء الامتحان أو الاختبار متلبساً بالغش فتوقع عليه العقوبات التالية مجتمعة:
أ- اعتباره راسباً في ذلك الامتحان أو الاختبار.
ب- الغاء تسجيله في بقية المساقات المسجل لها في ذلك الفصل.
جـ- فصله من الجامعة لمدة فصل دراسي واحد، و هو الفصل التالي للفصل الذي ضبط فيه.
Attendance / ·  JUST policy requires the faculty member to assign ZERO grade (35) if a student misses 10% of the classes that are not excused.
Graded Exams / ·  Instructor should return exam papers graded to students not after the week after the exam date.