ID Epi Class Part 1

Infectious Disease Epidemiologic Methods

-required for all Epi majors-

SPRING 2002

5 weeks (Jan 24 – Feb 21) 1 credit

Thursday evenings 5:30-8:30pm

Faculty: Maureen Miller, Crystal Fuller, Ezra Susser

Requirements:

Principles of Epidemiology (P6400)

Introduction to Biostatistical Methods (P6104)

Purpose:

The purpose of the class is to introduce infectious disease epidemiology history and some of the methods currently used in the conduct of infectious disease epidemiologic studies.

Organization:

The course will be a series of four lectures followed by a guided discussion of the topics presented. The four lectures will consist of a historical review of infectious disease epidemiology, and basic methodological and analytical approaches to the study of infectious disease risk. The final week of the course will be a final exam.

Grading:

100% of the grade will be based on the final exam.

Jan 24 History of Infectious Disease Epidemiology

Ezra Susser

Hamlin C, Sheard S. Revolutions in public health: 1848, and 1998? BMJ 1998;317:587-591.

Susser E, Bresnahan M. Origins of Epidemiology. (in press)

UNAIDS. Report on the global HIV/AIDS epidemic. June 2000.

Susser M. Causal thinking in the health sciences: concepts and strategies of epidemiology. Oxford University Press;New York, NY 1993. Chapters 2 and 3.

Jan 31 Introduction to modeling infectious disease risk

David Vlahov

Sartwell PE. The incubation period and the dynamics of infectious disease. Am J Epidemiol 1966 Mar;83(2):204-6

Armenian HK. Incubation periods of cancer: old and new. J Chronic Dis 1987;40 Suppl 2:9S-15S.

Munoz A, Sabin CA, Phillips AN. The incubation period of AIDS. AIDS 1997;11 Suppl A:S69-76

Vlahov D. The ALIVE Study: HIV seroconversion and progression to AIDS among intravenous drug users in Baltimore. HIV Epidemiology: Models and Methods. Raven Press, Ltd. New York, NY 1994

Feb 7 Multiple levels of infectious disease transmission risk: Environment, social network, and individual risk

Maureen Miller

Day S, Ward H, Ison C, Bell G, & Weber J. (1998). Sexual networks: the integration of social and genetic data. Social Science & Medicine, 47(12), 1981-1992.

Klovdahl AS, Graviss EA, Yaganehdoost A, Ross MC, Wanger A, Adams GJ, & Musser JM. (2001). Networks and tuberculosis: an undetected community outbreak involving public places. Social Science & Medicine, 52, 681-694.

Miller M, & Neaigus A. (2001). Networks, resources and risk among women who use drugs. Social Science & Medicine, 52, 967-978.

Rhodes T, Stimson GV, Crofts N, Ball A, Dehne K, & Khodakevich L. (1999). Drug injecting, rapid HIV spread, and the 'risk environment': implications for assessment and response. AIDS, 13(suppl A), S259-S269.

Susser M, & Susser E. (1996). Choosing a future for epidemiology II. From black box to chinese boxes and eco-epidemiology. American Journal of Public Health, 86(5), 674-677.

Feb 14 Recruitment and sampling methods in community-based infectious disease research

Crystal Fuller

Metzger DS, Woody GE, McLellan AT, et al. Human Immunodeficiency virus seroconversion among intravenous drug users in- and out-of-treatment: An 18-month prospective follow-up. J AIDS 1993;6:1049-56.

Alcabes P, Vlahov D, Anthony JC. Correlates of human immunodeficiency virus infection in intravenous drug users: are treatment program samples misleading? Brit J Addict 1992;87:47-54.

Master TD, Kitayaporn D, Weniger BG et al. Estimating the number of HIV-infected injection drug users in Bangkok: A capture-recapture method. Am J Public Health 1994; 84:1094-1099.

Watters JK, Biernacki P. Targeted sampling: Options for the study of hidden populations. Social Problems 1989; 36: 416-430.

Feb 21 In-class Exam