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Hepatic Cancers Checklist
(含hepatocellular carcinoma及intrahepatic cholangiocarcinoma)
Hepatocellular carcinoma
Diagnosis
Gross Description:
- Procedure
Wedge resection/Atypical hepatectomy
Right lobectomy/Left lobectomy/segmentectomy
Total hepatectomy
Other (specify): ______
- Tumor Focality: Solitary/Multiple (number: )
- Tumor Site: Right lob/ Left lobe/ Caudate lobe / Quadrate lobe
- Tumor Size: x x cm
- Satellitosis: Not identified/ Present
- Large vessel involvement: Not identified/ Present
- Non-tumorous part: cirrhotic/ Not cirrhotic
- Gallbladder: size: x x cm.
Gallstone: Not identified/Present
Sections are taken and labeled as:
Microscopic Description:
- Diagnosis: Hepatocellular carcinoma
Fibrolamellar carcinoma
Other histologic type not listed (specify): ______Carcinoma, type cannot be determined
- Histologic Grade: (According to the Edmondson and Steiner System)
G1: Well differentiated
G2: Moderately differentiated
G3: Poorly differentiated
G4: Undifferentiated
- Tumor Extension
Tumor confined to liver
Tumor involves a major branch of the portal vein
Tumor involves hepatic vein(s)
Tumor involves (perforates) visceral peritoneum
Tumor directly invades gallbladder
Tumor directly invades diaphragm
Tumor directly invades other adjacent organs (specify):______
- Parenchymal Margin
Uninvolved by invasive carcinoma
Distance of invasive carcinoma from margin: cm
Involved by invasive carcinoma
- Vascular Invasion
Not identified
Present: Small vessel invasion/Large vessel invasion
- ＊Perineural Invasion: Not identified/Present
- ＊Regional Lymph Nodes
No lymph nodes submitted or found
Number of lymph nodes involved/examined: /
- Pathologic Stage Classification (pTNM, AJCC 8th Edition)
Primary Tumor (pT)
pT1:Solitary tumor <2 cm, or >2 cm without vascular invasion
pT1a:Solitary tumor ≤2 cm
pT1b:Solitary tumor >2 cm without vascular invasion
pT2:Solitary tumor >2 cm with vascular invasion, or multiple tumors, none >5 cm
pT3:Multiple tumors, at least one of which is >5 cm
pT4:Single tumor or multiple tumors of any size involving a major branch of the portal vein or hepatic vein, or tumor(s) with direct invasion of adjacent organs other than the gallbladder or with perforation of visceral peritoneum
Regional Lymph Nodes (pN)
pNX: Regional lymph nodes cannot be assessed
pN0: No regional lymph node metastasis
pN1: Regional lymph node metastasis
Distant Metastasis (pM) (required only if confirmed pathologically in this case)
pM1: Distant metastasis
Specify site(s): ______
- Additional Pathologic Findings
None identified
Low-grade dysplastic nodule
High-grade dysplastic nodule
Steatosis
Steatohepatitis
Chronic hepatitis (specify etiology): ______
Other (specify): ______
- Ishak modified staging of fibrosis
(0) No fibrosis
(1) Fibrous expansion of some portal areas, with or without short fibrous septa
(2) Fibrous expansion of most portal areas, with or without short fibrous septa
(3) Fibrous expansion of most portal areas with occasional portal to portal bridging
(4) Fibrous expansion of portal areas with marked bridging (portal to portal as well as portal to central
(5) Marked bridging with occasional nodules (incomplete cirrhosis)
(6) Cirrhosis (probable or definite)
- Gallbladder: No pathologic change/Chronic cholecystitis/Cholelethiasis
- ＊Ancillary Studies
- ＊Comment(s)
Intrahepatic cholangiocarcinoma
Diagnosis
Gross Description:
1.Procedure
Wedge resection/Atypical hepatectomy
Right lobectomy/Left lobectomy/segmentectomy
Total hepatectomy
Other (specify): ______
2.Tumor Focality: Solitary/Multiple (number: )
3.Tumor Site: Right lob/ Left lobe/ Caudate lobe / Quadrate lobe
4.Tumor Size: x x cm
5.Non-tumorous part: cirrhotic/ Not cirrhotic
6.Gallbladder: size: x x cm.
Gallstone: Not identified/Present
Sections are taken and labeled as:
Microscopic Description:
- Diagnosis:
Intrahepatic cholangiocarcinoma
Combined hepatocellular-cholangiocarcinoma
Intraductal papillary neoplasm with an associated invasive carcinoma
Mucinous cystic neoplasm with an associated invasive carcinoma
- Histologic Grade:
G1: Well differentiated
G2: Moderately differentiated
G3: Poorly differentiated - Tumor Growth Pattern
Mass-formingPeriductal infiltrating
Mixed mass-forming and periductal infiltrating
Cannot be determined - Tumor Extension
Tumor confined to the intrahepatic bile ducts
Tumor confined to hepatic parenchyma
Tumor involves visceral peritoneal surface
Tumor directly invades gallbladder - Parenchymal Margin
Uninvolved by invasive carcinoma
Distance of invasive carcinoma from margin: cm
Involved by invasive carcinoma - Bile duct Margin
Uninvolved by invasive carcinoma
Involved by invasive carcinoma - Lymphovascular Invasion: Not identified/Present
- Perineural Invasion: Not identified/Present
- *Regional Lymph Nodes
No lymph nodes submitted or found
Number of lymph nodes involved/examined: / - Pathologic Stage Classification (pTNM, AJCC 8th Edition)
Primary Tumor (pT)
pTX:Primary tumor cannot be assessed
pT0:No evidence of primary tumor
pTis: Carcinoma in situ (intraductal tumor)
pT1: Solitary tumor without vascular invasion, ≤5 cm or >5 cm
pT1a: Solitary tumor ≤5 cm without vascular invasion
pT1b: Solitary tumor >5 cm without vascular invasion
pT2:Solitary tumor with intrahepatic vascular invasion, or multiple tumors, with or without vascular invasion
pT3:Tumor perforating the visceral peritoneum
pT4: Tumor involving local extrahepatic structures by direct invasion
Regional Lymph Nodes (pN)
pNX:Regional lymph nodes cannot be assessed
pN0:No regional lymph node metastasis
pN1:Regional lymph node metastasis present
Distant Metastasis (pM) (required only if confirmed pathologically in this case)
pM1:Distant metastasis
Specify site(s), if known: ______ - Additional Pathologic Findings
None identified
Chronic hepatitis (specify etiology): ______
Hepatolithiasis
Other (specify): _____ - Gallbladder: No pathologic change/Chronic cholecystitis/Cholelethiasis
- *Ancillary Studies
- *Comment(s)