THE LESSON PLANNER (SHORT FORM)

Teacher: __Lauren Ferris______Grade: __9-12__ Content Area: __Biology______Unit: __Genetics___

PLANNING FOR THE LESSON

Key Content Standard(s):

2. Mutation and sexual reproduction lead to genetic variation in a population.

e. Students know why approximately half of an individual’s DNA sequence comes from each parent.

f. Students know the role of chromosomes in determining an individual’s sex.

g. Students know how to predict possible combinations of alleles in a zygote from the genetic makeup of the parents.

3. A multicellular organism develops from a single zygote, and its phenotype depends on its genotype, which is established at fertilization.

a. Students know how to predict the probable outcome of phenotypes in a genetic cross from the genotypes of the parents and mode of inheritance (autosomal or X-linked, dominant or recessive).

c.* Students know how to predict the probable mode of inheritance from a pedigree diagram showing phenotypes.

Lesson Objective:

Students will research a genetic disorder of their choosing and create a visual presentation that demonstrates understanding of genetic/chromosomal disorders, inheritance, and effects of genotype on phenotype.

Understanding or Skill Students Will Enhance:

Students will enhance their understanding of genetics by exploring the specific effects of genotype on phenotype through human genetic disorders.

Assessment:

Rubric assessment of student created research project (poster, powerpoint, explaineverything, xtranorml, etc)

Academic Language Demands:

Students must understand scientific language regarding general genetic concepts as well as language specific to the chosen genetic disorder.

Resources/Materials:

Internet, Computer, Poster Board (optional)

Genetic Disorder Research Project

Introduction

Some disorders come from the environment. For example, diseases like the flu or AIDS are caused by viruses that a person may become infected with.

Other disorders are due to mistakes in the genes. A person is born with such disorders. Such disorders are usually inherited from the parents.

Assignment Guidelines

For this project you will research a genetic disorder from the list of possible topics below. There are many genetic disorders to choose from and you will only need to research one type. You may do this assignment alone or in a group of two students. Only one person or group may research a specific disorder. Students who do not choose a topic will be assigned one. If you would like to choose a genetic disorder not found in the list, be sure to ask your teacher before you begin your research.

Genetic/Chromosomal Disorders

Albinism

Alzheimer’s disease

Amyotrophic Lateral Sclerosis

Angelman Syndrome/ Prader-Willi Syndrome

Brachycactyly

Celiac Disease

Cri du chat Syndrome (Cat’s Cry Syndrome, Monosomy 5p)

Cystic Fibrosis

Diabetes, type 1 (Juvenile Diabetes) and Type 2

Down syndrome (Trisomy 21)

Duchenne Muscular Dystrophy

Edward’s Syndrome

Ehler Danlos Syndrome

Fragile X Syndrome

Hemophilia A or B

Huntington Disease

Ichthyosis

Klinefelter Syndrome (XXY Syndrome)

Lesch Nyhan Syndrome

Maple Syrup Urine Disease

Marfan syndrome

Multiple Sclerosis

Parkinson’s disease

Patau Syndrome

Phenylketonuria (PKU)

Polycystic Kidney Disease

Polydactyly

Sickle Cell Anemia

Tay - Sachs disease

Triple-X Syndrome (Trisomy X)

Turner’s syndrome

XYY Syndrome

Presentation Requirements

When you have researched your disorder type, you will produce a Poster, Powerpoint or Publisher presentation, ExplainEverything, or Xtranormal with the information you have collected. The presentation must include the following information:

Introduction

Name the disorder

Introduce team members

Definition of the disorder

What happens to the body?

What part of the body does it generally affect?

Description of the symptoms

List all of the possible effects on the body

Cause of the disorder

What happens in the body to cause the disease?

Is it a mutation? A genetic tendency triggered by other factors?

How the disorder is inherited

Is it sex-linked?

Is there a particular chromosome it is located on?

Is it recessive or dominant?

Make a drawing of how the disorder is inherited (Either a Punnette square or pedigree)

How the disorder is treated

Medications? Gene therapy?

How the disorder is diagnosed

What tests are done? Is genetic counseling an option?

How many and what type of people are likely to have the disorder

Is it more common in a certain group of people?

How common is it?

Application of research article

What new information did you learn from your research?

Useful Resources

The Genetic Science Learning Center is a useful source to obtain information on genetic disorders.

A comprehensive library of human diseases.

National Human Genome Research Institute (NHGRI)

This site from a National Institutes of Health affiliate provides information on genetics, inherited disease research, genetics and rare diseases, online resources, and the ethical, legal, and social issues related to genetic research.

Grading Rubric

A / B / C / D
Introduction / Title can be read from 6 ft. away and is quite creative. Includes group members. / Title can be read from 6 ft. away and describes content well. Includes group members. / Title can be read from 4 ft. away and describes the content. Includes group members. / The title is too small and/or does not describe the content of the poster well.
Definition / Answers each topic in-depth with details and examples. Subject knowledge is excellent. / Answers essential information about topic. Subject knowledge appears to be good. / Includes essential information about the topic but there are some factual errors. / Content is minimal OR there are several factual errors.
Symptoms / Answers each topic in-depth with details and examples. Subject knowledge is excellent. / Answers essential information about topic. Subject knowledge appears to be good. / Includes essential information about the topic but there are some factual errors. / Content is minimal OR there are several factual errors.
Cause / Answers each topic in-depth with details and examples. Subject knowledge is excellent. / Answers essential information about topic. Subject knowledge appears to be good. / Includes essential information about the topic but there are some factual errors. / Content is minimal OR there are several factual errors.
Inheritance / Answers each topic in-depth with details and examples. Subject knowledge is excellent. / Answers essential information about topic. Subject knowledge appears to be good. / Includes essential information about the topic but there are some factual errors. / Content is minimal OR there are several factual errors.
Treatment / Answers each topic in-depth with details and examples. Subject knowledge is excellent. / Answers essential information about topic. Subject knowledge appears to be good. / Includes essential information about the topic but there are some factual errors. / Content is minimal OR there are several factual errors.
Diagnosis / Answers each topic in-depth with details and examples. Subject knowledge is excellent. / Answers essential information about topic. Subject knowledge appears to be good. / Includes essential information about the topic but there are some factual errors. / Content is minimal OR there are several factual errors.
How many and what type of people are likely to have the disorder / Answers each topic in-depth with details and examples. Subject knowledge is excellent. / Answers essential information about topic. Subject knowledge appears to be good. / Includes essential information about the topic but there are some factual errors. / Content is minimal OR there are several factual errors.
Application of research article / Covers topic in-depth with details and examples. Subject knowledge is excellent. / Includes essential knowledge about the topic. Subject knowledge appears to be good. / Includes essential information about the topic but there are 1-2 factual errors. / Content is minimal OR there are several factual errors.
Attractiveness/ Presentation / The presentation is exceptionally attractive in terms of design, layout, and neatness. / The presentation is attractive in terms of design, layout and neatness / The presentation is acceptably attractive though it may be a bit messy. / The presentation is distractingly messy or very poorly designed. It is not attractive.

Due Date: ______Genetic Disorder: ______

Presentation Requirements / Earned Points / Possible Points
Introduction / 5
Definition of the disorder / 10
Description of the symptoms / 5
Cause of the disorder / 10
How the disorder is inherited / 20
How the disorder is treated / 5
How the disorder is diagnosed / 5
How many and what type of people are likely to have the disorder / 10
Application of research article / 5
Attractiveness/Presentation
Makes excellent use of font, color, graphics, effects, etc. to enhance the presentation. / 5
Total Points Earned / 80