WHNRC Nutritional Metabolomics Research Group
WHNRC Nutritional Metabolomics Research Group
Oxylipin Metabolite Profile
Common Name / Formal name / NotesPHAU / 1-Phenyl 3-Hexadecanoic Acid Urea / Internal stnd
CUDA / 1-Cyclohexyl Urea 3-Dodecanoic Acid / Internal stnd
6-keto PGF1α-d4 / Internal stnd
TXB2-d4 / Internal stnd
PGE2-d4 / Internal stnd
PGD2-d4 / Internal stnd
LTB4-d4 / Internal stnd
12(S)-HETE-d8 / 12(S)-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid / Internal stnd
9(S)-HODE-d4 / 9(S)-hydroxy-10E,12Z-octadecanoic-9,10,12,13-d4 acid / Internal stnd
5(S)-HETE-d8 / 5(S)-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid / Internal stnd
20-HETE-d6 / 20-hydroxy Arachidonic Acid-d6 / Internal stnd
10,11-DHHep / Internal stnd
11(12)-EpETrE-d8 / Internal stnd
PGB2-d4 / Internal stnd
9-12,13-TriHOME / 9(S),12(S),13(S)-Trihydroxy-11E-octadecenoic Acid / LA
9-10-13-TriHOME / LA
(±)12,13-DiHOME / (±)12,13-dihydroxy-9Z-Octadecanoic acid / LA P450 sEH
(±)9,10-DiHOME / (±)-9(10)-dihydroxy-12Z-Octadecanoic acid / LA P450 sEH
EKODE
(±)13-HODE / (±)-13-hydroxy-9Z,11E-Octadecanoic acid / LA
(±)9-HODE / (±)-9-hydroxy-10E,12Z-Octadecanoic acid / LA
13-KODE / 13-oxo-9Z,11E-octadecanoic acid / LA
9-KODE / 9-oxo-10E,12Z-octadecanoic acid / LA
12,13-EpOME / (±)12(13)epoxy-9Z-octadecanoic acid / LA P450
9(10)-EpOME / (±)9(10)epoxy-12Z-octadecanoic acid / LA P450
9,10-DiHODE / ALA
12,13-DiHODE / ALA
15,16-DiHODE / ALA
13-HOTE
9-HOTE
9(10)-EpODE / ALA
12(13)-EpODE / ALA
15(16)-EpODE / ALA
6-keto PGF1α / 6-oxo-9α, 11α,15S-trihydroxy-prost-13-en-1-oic acid / AA COX
TXB2 / 9α, 11,15S-trihydroxythromba-5Z,13E-dien-1-oic acid / AA COX
PGF2α / 9α, 11α,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid / AA COX
PGE1 / 9-oxo-11α,15S-dihydroxy-prost-13E-en-1-oic acid / AA COX
PGE2 / 9-oxo-11α,15S-dihydroxy-prosta-5E,13E-dien-1-oic acid / AA COX
PGE3 / 9-oxo-11α,15S-dihydroxy-prosta-5Z,13E,17Z-trien-1-oic acid / AA COX
PGD2 / Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, (5Z,9α,13E,15S)- / AA COX
PGB2 / 9-oxo-15S-hydroxy-prosta-5Z,8(12),13E-trien-1-oic acid / AA COX
PGJ2 / 11-oxo-15S-hydroxy-prosta-5Z,9,13E-trien-1-oic acid / AA COX
15-deoxy-Δ12,14-PGJ2 / 11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oic acid / AA COX
delta 12-PGJ2 / 11-oxo-15S-hydroxy-prosta-5Z,9,12E-trien-1-oic acid / AA COX
11,12,15-TriHETrE / 11,12,15-Trihydroxytrienoic
20-carboxy LTB4 / 5(S),12(R)-dihydroxy-6Z,8E,10E,14Z-eicosatetraenoic-1,20-dioic acid / AA LOX
20-hydroxy LTB4 / 6,8,10,14-Eicosatetraenoic acid, 5,12,20-trihydroxy-,[S-[R*,S*-(E,Z,E,Z0]]- / AA LOX
LTB5 / EPA > 5-HEPE
6-trans LTB4 / 5(S),12(R)-dihydroxy-6E,8E,10E,14Z-eicosatetraenoic acid / non enz
LTB4 / 5(S),12(R)-dihydroxy-6Z,8E,10E,14Z-eicosatetraenoic acid / AA LOX
LTC4 / AA LOX
LTD4 / AA LOX
LTE4 / AA LOX
LXA4 / 5(S),6(R),15(S)-trihydroxy-7E,9E,11Z,13E-eicosatertraenoic acid
(±)14,15-DiHETrE / (±)14,15-dihydroxy-5Z,8Z,11Z-eicosatrienoic acid / AA P450 sEH
(±)11,12-DiHETrE / (±)11,12-dihydroxy-5Z,8Z,14Z-eicosatrtienoic acid / AA P450 sEH
(±)8,9-DiHETrE / (±)8,9-dihydroxy-5Z,11Z,14Z-eicosatrtienoic acid / AA P450 sEH
(±)5,6-DiHETrE / (±)5,6-dihydroxy-8Z,11Z,14Z-eicosatrtienoic acid / AA P450 sEH
20-HETE / 20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid / AA
(±)15-HETE / 5,8,11,13-eicosatetraenoic acid, 15-hydroxy,(E,Z,Z,Z)-(±)- / AA
(±)12-HETE / 5,8,10,14-eicosatetraenoic acid, 12-hydroxy,(E,Z,Z,Z)-(±)- / AA
(±)11-HETE / AA
(±)9-HETE / AA
(±)8-HETE / AA
(±)5-HETE / AA
15(S)-HETrE / GLA 15-LOX (inh 5-LOX)
15-KETE / AA
5-KETE / AA
(±)14(15)-EpETrE / AA P450
(±)11(12)-EpETrE / AA P450
(±)8(9)-EpETrE / AA P450
(±)5(6)-EpETrE / AA P450
DiHETHF / Tetrahydrafuran (Falck)
(±)14,15-DiHETE / (±)14,15-Dihydroxy-Eicosa-5,8,11,17-Tetraenoic Acid / EPA
(±)17,18-DiHETE / (±)17,18-Dihydroxy-Eicosa-5,8,11,14-Tetraenoic Acid / EPA
5(S),15(S)-DiHETE / 5(S),15(S)-DiHETE / 15-LOX eosin
8(S),15(S)-DiHETE / 8(S),15(S)-DiHETE
(±)15-HEPE
(±)12-HEPE
5(S)-HEPE
RvE1 / EPA
17(R)-HDoHE / DHA
EPA
ALA
DHA
AA
LA