Li Treatment and weight gain

The required data concerning the initial weight and drug intake of the different groups of the experiment and the results of the changes that occurred in their weight gain and drug intake are given in Tables I-IX. The observed rates of dosage are compatible with the subjects’ levels of weekly weight changes.

Table 1 Descriptive Statistics for Group I – Standard Drug 10 mg/kg.day
N / Mean / Std. Deviation / Variance / Skewness
Statistic / Statistic / Std. Error / Statistic / Statistic / Statistic / Std. Error
Initiial weight (gr) / 6 / 245.83333 / 5.833333 / 14.288690 / 204.167 / -.173 / .845
Week1 / 6 / 255.83333 / 4.362084 / 10.684880 / 114.167 / -.137 / .845
Week2 / 6 / 260.00000 / 5.916080 / 14.491377 / 210.000 / .591 / .845
Week3 / 6 / 271.66667 / 6.411795 / 15.705625 / 246.667 / .120 / .845
Week4 / 6 / 285.83333 / 7.236098 / 17.724747 / 314.167 / -.165 / .845
Initial Drug intake (mg/kg.day) / 6 / .25117 / .005997 / .014689 / .000 / -.139 / .845
Week1 / 6 / .26150 / .004530 / .011095 / .000 / -.189 / .845
Week2 / 6 / .26550 / .006114 / .014977 / .000 / .563 / .845
Week3 / 6 / .27750 / .006526 / .015984 / .000 / .053 / .845
Week4 / 5 / .29620 / .006288 / .014061 / .000 / .680 / .913
Table 2 Descriptive Statistics for Group II – Standard Drug 20 mg/kg.day
N / Mean / Std. Deviation / Variance / Skewness
Statistic / Statistic / Std. Error / Statistic / Statistic / Statistic / Std. Error
Initial weight (gr) / 6 / 245.00 / 5.164 / 12.649 / 160.000 / .334 / .845
Week1 / 6 / 248.33 / 4.410 / 10.801 / 116.667 / .463 / .845
Week2 / 6 / 265.00 / 2.887 / 7.071 / 50.000 / .000 / .845
Week3 / 6 / 273.33 / 4.216 / 10.328 / 106.667 / .461 / .845
Week4 / 6 / 287.50 / 3.096 / 7.583 / 57.500 / .774 / .845
Initial drug intake (mg/kg.day) / 6 / .50133 / .010522 / .025773 / .001 / .355 / .845
Week1 / 6 / .50800 / .008996 / .022036 / .000 / .480 / .845
Week2 / 6 / .54217 / .005890 / .014428 / .000 / .074 / .845
Week3 / 6 / .55933 / .008605 / .021078 / .000 / .406 / .845
Week4 / 6 / .58817 / .006327 / .015497 / .000 / .834 / .845
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Table 3 Descriptive Statistics for Group III – Standard Drug 30 mg/kg.day
N / Mean / Std. Deviation / Variance / Skewness
Statistic / Statistic / Std. Error / Statistic / Statistic / Statistic / Std. Error
Initial weight (gr) / 6 / 245.83 / 4.167 / 10.206 / 104.167 / -.333 / .845
Week1 / 6 / 256.67 / 3.073 / 7.528 / 56.667 / -.840 / .845
Week2 / 6 / 271.67 / 6.412 / 15.706 / 246.667 / -.228 / .845
Week3 / 6 / 284.17 / 8.507 / 20.837 / 434.167 / -.744 / .845
Week4 / 6 / 291.67 / 9.006 / 22.061 / 486.667 / -.879 / .845
Initial drug intake (mg/kg.day) / 6 / .75450 / .012740 / .031207 / .001 / -.328 / .845
Week1 / 6 / .78783 / .009509 / .023293 / .001 / -.807 / .845
Week2 / 6 / .83400 / .019730 / .048328 / .002 / -.248 / .845
Week3 / 6 / .87217 / .026121 / .063983 / .004 / -.758 / .845
Week4 / 6 / .89533 / .027562 / .067512 / .005 / -.882 / .845
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Table 4 Descriptive Statistics for Group IV – Nanodrug 10 mg/kg.day
N / Mean / Std. Deviation / Variance / Skewness
Statistic / Statistic / Std. Error / Statistic / Statistic / Statistic / Std. Error
Initial weight (gr) / 6 / 260.83 / 3.270 / 8.010 / 64.167 / .041 / .845
Week1 / 6 / 265.83 / 3.962 / 9.704 / 94.167 / 2.116 / .845
Week2 / 6 / 282.50 / 2.814 / 6.892 / 47.500 / -1.375 / .845
Week3 / 6 / 291.67 / 3.801 / 9.309 / 86.667 / -1.281 / .845
Week4 / 6 / 302.50 / 2.500 / 6.124 / 37.500 / -.490 / .845
Initial drug intake (mg/kg.day) / 6 / .46083 / .005718 / .014006 / .000 / .088 / .845
Week1 / 6 / .46950 / .007131 / .017467 / .000 / 2.116 / .845
Week2 / 6 / .50017 / .005134 / .012576 / .000 / -1.228 / .845
Week3 / 6 / .51550 / .006667 / .016331 / .000 / -1.339 / .845
Week4 / 6 / .53450 / .004500 / .011023 / .000 / -.490 / .845
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Table 5 Descriptive Statistics for Group V – Nanodrug 20 mg/kg.day
N / Mean / Std. Deviation / Variance / Skewness
Statistic / Statistic / Std. Error / Statistic / Statistic / Statistic / Std. Error
Initial weight (gr) / 6 / 252.50 / 4.610 / 11.292 / 127.500 / -2.188 / .845
Week1 / 6 / 266.67 / 6.412 / 15.706 / 246.667 / .120 / .845
Week2 / 5 / 275.00 / 9.874 / 22.079 / 487.500 / .029 / .913
Week3 / 5 / 281.00 / 9.670 / 21.622 / 467.500 / .330 / .913
Week4 / 5 / 292.00 / 11.136 / 24.900 / 620.000 / .454 / .913
Initialdrugintake (mg/kg.day) / 6 / .89283 / .016325 / .039987 / .002 / -2.208 / .845
Week1 / 6 / .94350 / .022643 / .055464 / .003 / .085 / .845
Week2 / 5 / .97460 / .035041 / .078354 / .006 / .023 / .913
Week3 / 5 / .99160 / .033134 / .074090 / .005 / .272 / .913
Week4 / 5 / 1.02960 / .039162 / .087569 / .008 / .566 / .913
Table 6 Descriptive Statistics for Group VI – Nanodrug 30 mg/kg.day
N / Mean / Std. Deviation / Variance / Skewness
Statistic / Statistic / Std. Error / Statistic / Statistic / Statistic / Std. Error
Initialweight (gr) / 6 / 260.83 / 3.270 / 8.010 / 64.167 / .041 / .845
Week1 / 6 / 259.17 / 4.167 / 10.206 / 104.167 / -1.572 / .845
Week2 / 6 / 265.83 / 3.270 / 8.010 / 64.167 / -2.148 / .845
Week3 / 5 / 268.00 / 4.637 / 10.368 / 107.500 / -1.918 / .913
Week4 / 5 / 284.00 / 3.674 / 8.216 / 67.500 / -1.736 / .913
Initial drug intake (mg/kg.day) / 6 / 1.38350 / .017303 / .042383 / .002 / .037 / .845
Week1 / 6 / 1.37783 / .022194 / .054363 / .003 / -1.547 / .845
Week2 / 6 / 1.41350 / .017659 / .043256 / .002 / -2.148 / .845
Week3 / 5 / 1.42160 / .024651 / .055121 / .003 / -1.908 / .913
Week4 / 5 / 1.50280 / .018640 / .041680 / .002 / -1.980 / .913
Table 7 Descriptive Statistics for Group VII – Nanoblank 10 mg/kg.day
N / Mean / Std. Deviation / Variance / Skewness
Statistic / Statistic / Std. Error / Statistic / Statistic / Statistic / Std. Error
Initial weight (gr) / 2 / 190.00 / .000 / .000 / .000 / . / .
Week1 / 2 / 242.50 / 7.500 / 10.607 / 112.500 / . / .
Week2 / 2 / 255.00 / 10.000 / 14.142 / 200.000 / . / .
Week3 / 2 / 255.00 / 10.000 / 14.142 / 200.000 / . / .
Week4 / 2 / 272.50 / 12.500 / 17.678 / 312.500 / . / .
Initial drug intake (mg/kg.day) / 2 / .33600 / .000000 / .000000 / .000 / . / .
Week1 / 2 / .42850 / .013500 / .019092 / .000 / . / .
Week2 / 2 / .45150 / .017500 / .024749 / .001 / . / .
Week3 / 2 / .45050 / .017500 / .024749 / .001 / . / .
Week4 / 2 / .48150 / .022500 / .031820 / .001 / . / .
Table 8 Descriptive Statistics for Group VIII – Nanoblank 20 mg/kg.day
N / Mean / Std. Deviation / Variance / Skewness
Statistic / Statistic / Std. Error / Statistic / Statistic / Statistic / Std. Error
Initialweight (gr) / 2 / 227.50 / 32.500 / 45.962 / 2112.500 / . / .
Week1 / 2 / 255.00 / 5.000 / 7.071 / 50.000 / . / .
Week2 / 2 / 267.50 / 7.500 / 10.607 / 112.500 / . / .
Week3 / 2 / 265.00 / .000 / .000 / .000 / . / .
Week4 / 2 / 277.50 / 2.500 / 3.536 / 12.500 / . / .
Initialdrugintake (mg/kg.day) / 2 / .80400 / .115000 / .162635 / .026 / . / .
Week1 / 2 / .90150 / .017500 / .024749 / .001 / . / .
Week2 / 2 / .94800 / .027000 / .038184 / .001 / . / .
Week3 / 2 / .93700 / .000000 / .000000 / .000 / . / .
Week4 / 2 / .98100 / .009000 / .012728 / .000 / . / .
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Table 9 Descriptive Statistics for Group IX – Nanoblank 30 mg/kg.day
N / Mean / Std. Deviation / Variance / Skewness
Statistic / Statistic / Std. Error / Statistic / Statistic / Statistic / Std. Error
Initial weight (gr) / 2 / 280.00 / 10.000 / 14.142 / 200.000 / . / .
Week1 / 1 / 260.00 / . / . / . / . / .
Week2 / 1 / 290.00 / . / . / . / . / .
Week3 / 1 / 260.00 / . / . / . / . / .
Week4 / 1 / 300.00 / . / . / . / . / .
Initial drug intake (mg/kg.day) / 2 / 1.48550 / .053500 / .075660 / .006 / . / .
Week1d / 1 / 1.40200 / . / . / . / . / .
Week2d / 1 / 1.54200 / . / . / . / . / .
Week3d / 1 / 1.37900 / . / . / . / . / .
Week4d / 1 / 1.59200 / . / . / . / . / .
Valid N (listwise) / 1

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