Lab Report Format for Separating the Components of “Panacetin” (2) and Recrystallization and Melting Point Measurement: Identifying the Components of “Panacetin” (3).
1. Title Page
a. A descriptive title with between 15-25 words.
b. Dates the experiment was performed.
c. Course and section numbers.
d. Your name
e. Tape your TLC plate to the bottom of the page. Clearly label each column of spots on the page so I know what it is.
2. Body of the report (start a new page)
a. Panacetin sample number.
b. Weight of initial panacetin sample.
c. Weight of sucrose collected.
d. Weight of aspirin collected.
e. Melting point range of aspirin.
f. Weight of unknown compound isolated in Expt. 2.
g. Weight of recrystallized unknown compound in Expt. 3.
h. Melting point range of recrystallized unknown compound.
i. Mixture melting point ranges of the unknown compound with acetanilide and with phenacetin.
j. Show your calculations of the percent recoveries of sucrose, aspirin and your unknown (divide the weight of each solid by answer in b., ´ 100%).
k. What was the identity of your unknown? Explain in detail how you determined it, comparing the data you obtained with known values. Explain any discrepancies.
3. Questions
a. Where in the separation procedure could you lose one or more of the Panacetin components? Explain which component could be lost in which step. Ignore trace amounts left in containers, or blatant spills.
b. In the separation scheme, the dichloromethane solution is extracted with sodium hydroxide. What would happen if the dichloromethane solution was extracted with hydrochloric acid instead (which has actually happened)? Would the separation scheme still work? Explain your reasoning.
c. Acetaminophen (the active ingredient in Tylenol) is insoluble in water, soluble in sodium hydroxide solution, insoluble in hydrochloric acid, and insoluble in dichloromethane. If your Panacetin sample contained acetaminophen, where would it be separated in the separation scheme? Explain your reasoning.