Onmy-LBA*0101 1 TACGCGAGGCTACATTTTCT

LCAtr

Onmy-LAA*0101 1 GGCGGAACTTCATGGTCGTCTACACCAGCTGTATGGAAACTGAAGTGCTTT

Onmy-LBA*0101 1 TACGCGAGGCTACATTTTCT

Onmy-LCA*0101 1 CCCCCAAAAAGCTACACAACCAACTGTGTAGCATATTGTTATT-CATAGCTAAAAGAAAGGGGAAGTCTGTCAGACACTCTTGAGAGCTTAGAAACTTGCTACGCGAGGCTACATTTTCT

Onmy-LDA*0101 1 TGCAGACGCAGGAATGCCCACGTGCAGCTACGAAGTATATATTATTTTTAGAAGTGAAACAGGAAGTCTGTCAGAAAC--TTGAGA------CATGCTACACAAGGCTACACTT-CA

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Leader Intron 1

M N F Y T L F L I Y L P I V N A

Onmy-LAA*0101 52 GAA--ATGAATTTTTACACGTTATTTCTCATATATCTTCCA------ATTGTTAATGCAGGTAA---GGTCTATTGATTTT-TCACAAGTGGATTGCTGGAATTTAGTCTTGCTGAG

Onmy-LBA*0101 21 AAATCATGGGCAAACTATCTATCTTTTTGTTTGCTCTTTCCTTTTGCACCATTGTCAACTCAGGTAATATGGACTATTTACTTTATCTCAA-CTCATTAAATGA-TTTGTTATGTTATAA

Onmy-LCA*0101 120 AAATCATGGGCAAACTGTCTGTCTTTTTGTTTGTTCTTTCCTTTTGCACCATTGTCAACTCAGGTAATATGGACTATTTACTTTATCTCAA-CTCATTAAATGA-TTTGTTATGTTATAA

Onmy-LDA*0101 109 AAATCATGGGCAAACTGTCAATCTTTTTGTTTGTTCTTTCATTTTACACCATTGTCAACGCAGGTAAGATGGACTACTAACTTTCTCTCAAACTCATTTAATGA-CTT-TTATGTCATAA

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pLAA-L-F1, pLBA-L-F1, pLCA-L-F1, pLDA-L-F1

alpha1

G K S S H S L W G L A T H V L G E T E F P E F C V

Onmy-LAA*0101 157 AATTACTAAT------TGATT----TATCAC----CTCACAGGTAAATCTTCCCACTCTCTGTGGGGGTTAGCAACACACGTACTTGGAGAGACAGAGTTTCCTGAATTCTGTGTTT

Onmy-LBA*0101 139 AATATAAAATGTTCATAACTCATTTTAATATAACTGCTCTCCCAGGTTCAGGATCACATTCTCTGTGGGCACTTGCAACATATATAAGTGGAGAGACGCCTTTCCCTGAGTTTACGGTTG

Onmy-LCA*0101 238 AATATAAAATGTTCATAACTCATTTTAATATAACTGCTCTCCCAGGTTCAGGATCACATTCTCTGTGGGCACTTGCAACATATATAAGTGGAGAGACGCCTTTCCCTGAGTTTACGGTTG

Onmy-LDA*0101 227 AATGTTAACGGTCCACAACGGTGTATAATGTCACTCTTTTCTCAGGTTCAGGATCACATTCTCTGTGGGCACTTGCAACATACATAATCGGAGAGACACCTTTCCCTGAGTTTACAGTTG

*** . .*...... * ...*.* **. ..** *****..*...**.**.**********...*.******.* .**. .******** ...**.*****.**... ***.

pLAA-a1-F1

L W M L D D V Q V G Y Y D S N S W R F I S R T D E N I D E E Y S K T V Q G A S

Onmy-LAA*0101 260 TGTGGATGCTGGATGATGTTCAGGTGGGATACTATGACTCCAATTCCTGGAGATTTATCTCTAGGACCGATGAGAACATAGATGAGGAGTATTCAAAAACAGTTCAGGGTGCGTCTT---

Onmy-LBA*0101 259 TGGTGATGTTGGATGACATTCAAGTGACTTACTATGACTCCAACATGAAACACTTCATCTACAAGGGACATAACACCTCAGACAAAATACATGATGATGAAGCTAAGAACGGAGATTTTG

Onmy-LCA*0101 358 TGGTGATGTTGGATGATGTTCAAGTGACTTACTATGACTCCAACATGAAACACTTCATCTACAAGGGACATAACACCTCAGACAAAATACATGATGATGAAGCTAAGAACGGAGATTTTG

Onmy-LDA*0101 347 TGTTGATGTTGGATGATGTTCAAATAGGTTACTATGACTCCAACATTAAACTGTCTGTCTACAGGGGTTACCATATTACAGACAAAATA---AATGACGAAGCTCAGGATGGAAGTGATG

Onmy-LEA*0101 1 AAAATGCATGATAACAAAGCTCAGGACGGAGCTTATG

** .****.*******..****..*. .**************...... *. .***..* *.. *. * * . .***..*...... * ..**.*.**...*... *. ..

alpha2

W D V Y L S M R K R S S L L Q H R F N S T T G I F V H Q R L I G C E L E D N

Onmy-LAA*0101 377 ------GGGACGTGTACCTCAGTATGAGGAAGCGGTCGTCCCTCTTACAGCACCGCTTTAACTCCACAACAGGAATATTTGTTCATCAGAGACTTATTGGTTGTGAATTGGAGGACAATG

Onmy-LBA*0101 379 TATTTGGAGTTATGTACCACCACATGAAGGAGAGATACTTTCACCTAAAGCACCACTTTAATCTCACGGAAGGTGTTCAAGTTCAGCAAAAATTAACTGGCTGTGAGATGTTTGACAATG

Onmy-LCA*0101 478 TATTTGGAGTTATGTACCACCACATGAAGGAGAGATACTTTCACCTAAAGCACCACTTGAATCTCACGGAAGGTGTTCAAGTTCAGCAAAGAATGGCTGGCTGTGAGATGTTTGACAATG

Onmy-LDA*0101 464 TACTTGGAACTATGTACCACCACATGAAAGAGAGATCATTTCGCCTAAAGCACCACTTAAATCTCACGGAAGGTGTTCACGTTCAGCAAAGAATTGGTGGCTGTGAGATATTGCACAATG

Onmy-LEA*0101 38 TATTTGGAATGATGTTCAACAACATGAAAGAGAGATCATTTAACCTAAAGCACCACTTCAACCTCACGGAAGGTGTTCAAGTTCAGCAAAGAATGTCTGGCTGTGAGATGTTGGACAATG

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pLAA-a1-R1

E K Q G Q L M I K E A F N G I D G G V L N F N K L Q Y N Y H P K W P E L E

Onmy-LAA*0101 491 AAAAGCAAGGCCAACTCATGATAAAGGAAGCGTTCAATGGAATTGATGGAGGT---GTTCTGAACTTCAACA------AACTGCAGTACAATTACCATCCTAAGTGGCCAGAACTTGAGT

Onmy-LBA*0101 499 GTGAACCAGCCTTGGTCATGTTTAAGGATGCGTTCAATGCCATTTATACAGATCGAACATTATATTACAACATGACACATTTTACGTACGATGCTGGGAAACTACTACTAGGA------T

Onmy-LCA*0101 598 GTGAACCAGCCCTGATCATGACAAAGAATACTTTCAATGCAGTTTTTGTAGATCATGCAATATATTACAACATGACACATTTTACATATGATGCTGGTAAACTACTGCAAGGA------T

Onmy-LDA*0101 584 GTGAACCGGCCCTGATCATGACAAAGAACTCTTTTAATGGAATTTTTGCAGATTATGCGGTATATTACAACATGACACATTTTACATATGATTCTGGGCAACTCCTACTAGGA------T

Onmy-LEA*0101 158 GTGAACCGGTCATGTTCGTGGTAAAGGACACTTTCAATGCCATTTATACAGATCAAATGGTATGTTACAACATGACACATTTTATATATGATGCTGGGAAACTTCTACGAGGA------T

...*.*..*.*... **.**...***.* *.**.****...**..*..**.*.. .. *....*.*****...... *..*....**..**...... * **.* *

pLAA-a2-R1

F N Q Q R T Q Y I Q M G L D K V Y L P I C I K S L K D Y L K K E E K L V M R K V

Onmy-LAA*0101 602 TTAATCAACAAAGGACACAGTACATTCAAATGGGTCTTGACAAGGTTTATCTCCCTATTTGCATTAAATCATTAAAGGACTACCTGAAGAAAGAAGAGAAACTGGTCATGAGAAAAGTGC

Onmy-LBA*0101 613 GGGATGGGATGAGGCAAGCATATGAAAGAACACTTTATGAGAATGTTTACCTTCCTATTTGTATAAAATCACTGAAAAAAATCCTGAAGAGAGAGAAGAACGTTGTGATGCGTAAAGTTC

Onmy-LCA*0101 712 GGGATGGGATGAGGCAATTACAGGAAAAAATTCTTTATGAGAATGTTTTACTTACCCTTTGCATCAGAACACTGAAGACAATCCTGAAGAGAGAGAAGAACGTTATGATGCGTAAAGTTC

Onmy-LDA*0101 698 ATAATTGGATGAGGCAAGCAACTGAAAGAACACTTTATGCTAATGTTTGGCTTCCTATTTGCATCAACACACTGAAAAAATGCCTGAACAGAGAGAAGAACTTTGTGATGCGGAGAGTGC

Onmy-LEA*0101 272 GGGATGGGATGAGGCAAGCGTTTGAAAGAGTATTATTTGAGAATGTTCATCTTCCCATTTGCATCAGAACACTGAAGACAATCCTGAAGAGAGAGAAGAACTTTGCGATGCGTAAAGTTC

...**...... ***..*...... *...... **..**.***.. **..*..****.**.*...**.*.**...... ******.*.***..****. *....***.*.*.***.*

pLBA-a2-R1, pLCA-a2-R1, pLDA-a2-R1

alpha3

R P R V R L I S K E S T D T E G A K I T C L A F G F Y P R H I N L T L L R D G Q

Onmy-LAA*0101 722 GTCCTAGAGTAAGACTCATTTCAAAAGAAAGCACAGATACTGAAGGGGCCAAGATCACCTGCCTGGCCTTTGGTTTCTACCCCCGCCACATCAACCTCACCCTGCTGAGAGACGGCCAAC

Onmy-LBA*0101 733 CTCCCAGACTCAGG----TTGATAAAGAAAG--AGGTTTCTGGAGGGTTTCAGGTGAGCTGCCTGGCGTTTGGTTTCTACCCCCGCCACATCAACCTGACCCTGCTGAGAGACGGCCAGC

Onmy-LCA*0101 832 CTCCCAGACTCAGG----TTGATAAAGAAAG--AGGTTTCTGGAGGGTTCCAGGTGAGCTGCCTGGCGTTTGGTTTCTATCCCCGCCACATCAACCTGACCCTGCTGAGAGACGGCCAGC

Onmy-LDA*0101 818 CTCCCAGACTCAGACTC-TTGATAAAGAAAG--AGGTTTCTGGAGACCTCCAGGTGATCTGCCTGGCGTTTGGTTTCTACCCCCGCCACATCAACTTGACCCTGCTGAGAGACGGCCATC

Onmy-LEA*0101 392 CTCCCAGACTCAGG----TTGATAAAGAAAG--AGGTTTCTGGAGGGCTCAAGGTGAGCTGCCTGGCGTTTGGTTTCTACCCCCGCCACATCAACCTGACCCTGCTGAGAGACGGCCAGC

.***.***.*.**. **...******** ....*.***.**.. ...**.*.*.*********.***********.***************.*.********************.*

P V A E H E L K G G Q L L P N G D W T Y Q L R K S L T I T V Q E L R E R P N Y T

Onmy-LAA*0101 842 CTGTGGCAGAGCATGAGCTCAAAGGGGGGCAATTGCTACCGAATGGAGACTGGACGTACCAGCTGAGAAAGAGTCTGACAATCACTGTCCAGGAGCTGAGAGAGAGACCCAACTACACCT

Onmy-LBA*0101 847 CAGTGGCAGAACAGGAGCTGACAGGGGGGGAGGTTCTGCCTAGTGGAGACGGGACCTACCAGTTGAGGAAGAGTCTGGAGGTCAGTACTGAGGAGCTAAAGAAGAGACACAATTACACCT

Onmy-LCA*0101 946 CAGTGGCAGAACAGGAGCTGACAGGGGGGGAGGTTCTGCCTAGTGGAGACAGGACCTACCAGCTGAGGAAGCGTCTGGAGGTCAGTACTGAGGAGCTAAAGAAGAGACATAACTACACCT

Onmy-LDA*0101 935 CAGTGGCAGAACAGGAGCTGACAGGGGGGGAGGTACTGCCTAGTGGAGACGGGACCTACCAGCTGAGGAAGAGTATTTATGTCAGTACTGAGGAGCTAAGGGAGAAACACAACTACACCT

Onmy-LEA*0101 506 CAGTGGCAGAACAGGATCTGACAGGGGGGGAGGTTCTGCCTAGTGGAGACGGGACCTACCAGCTGAGGAAGAGTCTGGAGGTCAGTACTGAGGAGCTAAAGAAGAGACACAACTACACCT

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TM/CY

C T A N H I S M D N K L D V S W V P D T G P D S A S I I P V V L V M A V V L I L

Onmy-LAA*0101 962 GCACTGCCAATCACATCAGTATGGACAACAAGCTGGATGTCAGTTGGGTTCCTGATACTGGCCCAGATAGCGCCTCCATCATTCCAGTCGTTCTGGTAATGGCAGTCGTGTTAATTCTGA

Onmy-LBA*0101 967 GTACTGCCTCTCACCTCAGTCTGGACAACAAGCTGGATGTCAGTTGGGAGTCTGGGGCAGAGAGAGTTCACCTATCCACCCTCTCAGCTCTACTGGTGATGCTGCTGGTTGTTATTCTAT

Onmy-LCA*0101 1066 GTACTGCCTCTCACCTCAGTCTGGACAACAAGCTGGATGTCAGTTGGGAGTCTGGGGCAGAGAGAGTTCACCTATCCACCCTCTCAGCTCTACTGGTGATGCTGCTGGTTGTTATTCTAT

Onmy-LDA*0101 1055 GCACTGCCTCTCACCTCAGTCTGAACAACAAGCTGGATGTCAGTTGGGAGTCTGGGGCAGAGAGAGTTCACCTATTCATCCTCTCAGCTCCACTGGTGATGGCGCTGATTGTTATTCTGT

Onmy-LEA*0101 626 GTACTGCCTCTCACCTCAGTCTGGACAACAAGCTGGATGTCAGTTGGGAGTCTGGGGCAGAGAGAGTTCACCTATCCACCTTCTCAGCTCTACTGGTGATGCTGCTGATTGTTATTCTAT

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I G I L V V I G M W K W K H A G V P T F S G H I Y S A A K D T E T E Q S N S S

Onmy-LAA*0101 1082 TTGGGATCCTTGTTGTTATTGGCATGTGGAAGTGGAAACACGCAGGCGTTCCTACATTTTCTGGACATATATACTCT---GCTGCCAAAGATACTGAGACAGAACAGAGTAACTCCTCTT

Onmy-LBA*0101 1087 TCAGCAT---TTTCATTTGTGTCAAAAGGAGGTGGAGTAACACTGCCTCACAGTCT------AAACTTGCCAACGTTGATGCAACAGTGTCAGAG---GAAATTAACCTTTCTTCA-

Onmy-LCA*0101 1186 TCAGCAT---TTTCATTTGTGTCAAAAGGAGGTGGAGTAACACTGCCTCTCAGTCT------AAACTGGTCAATGTTGATGCAACAGTGTCAGAG---GAAATGAACCTTTCTTCA-

Onmy-LDA*0101 1175 TCTGCAT---TTTAATTTGCCTCGCAAGGAGGATACGC---GCCGCATCGCAGAATTTG------CAACTAGCCAGCGTTGATGCATTAGAGGCAGAT---GAAAGGAACCTGTCATCA-

Onmy-LEA*0101 746 TGGGCAT---TTTCATTTGCGTT---AGGAGGTGGAGATACACTGCCTCACAGTCT------AAAATTGCCAACGTTGATGCAAAAGTGTCAGAG---GAAATGAACCTTTCTTCA-

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L E T E S T D S

Onmy-LAA*0101 1199 TAGAGACAGAATCAACAGATTCTTGATACTACTGTACTCATAACATCTCT

Onmy-LBA*0101 1192 --GATTCTGAGACCTGATACATTTT

Onmy-LCA*0101 1291 --GATTCTGAGAACTAATACATTAT

Onmy-LDA*0101 1280 --GATTCTGAGATCTAA

Onmy-LEA*0101 848 --GATTCTGAGACCTAA

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