Croup Guidelines – Nsambya Hospital

Croup (larynotracheal bronchitis) is an acute inflammatory condition that causes narrowing of the subglottic region of the larynx. It is usually caused by a viral infection, including (but not exclusively) parainfluenza, influenza, RSV.

Signs:

-Stridor

-Barking cough

-Hoarseness

-Respiratory distress

-+/- fever

- +/- flu like illness

Where appropriate (if severity allows) a HANDS OFF APPROACH is best for initial assessment as patients can become very distressed with examination and symptoms worsen as a result.

Differential diagnosis:

Other causes of upper airway obstruction.

Main causes:

-acute foreign body aspiration

-acute anaphylaxis

-bacterial upper airway infection (epiglottitis, bacterial tracheitis)

Differentiation between croup, tracheitis, epiglottitis

CROUP / TRACHEITIS / EPIGLOTTITIS
Cause / Viral / Staph Aureus
Streptococcus / Haem. Influenza B
Age / 6M- 3yrs / Any age / 2-6yrs
Onset / Gradual / Gradual / Sudden
Pyrexia / Mild / >38 / >38
Abnormal sounds / Barking cough, stridor / Barking cough, stridor / Muffled, guttural cough
Swallowing / Normal / Difficult / Very difficult with drooling
Posture / Recumbent / Sitting / Tripod position
Facies / Normal / Anxious / Anxious, distressed, toxaemic

Bacterial tracheitis: infection of tracheal mucosa leading to copious secretions and mucosual necrosis. Child is usually ‘toxic’ looking, high temp, and requires IV antibiotics (usually cefotaxime and flucloxacillin).

Epiglottis is caused by haemophilus influenza B, and is intense swelling of epiglottis and surrounding tissues leading to airway obstruction. . Cough is usually minimal or absent. Child is toxic with a high fever and often drooling. IV cefotaxime and anaesthetic assessment of airway is needed, avoid unnecessary examination.

ASSESSING SEVERITY/SCORING:

Westley Croup scoring:

0 points / 1 point / 2 points / 3 points / 4 points / 5 points
Inspiratory stridor / Nil / When agitated/active / At rest
Intecostal recessions / Nil / Mild / Moderate / Severe
Air entry / Normal / Mildly decreased / Severely decreased
Cyanosis / None / With agitation/activity / At rest
Level of consciousnes / Normal / Altered

<4 = Mild croup

4-6 = Moderate

>6 = Severe croup

INVESTIGATIONS

CBC may be non specific.

CXR: can exclude other causes if no improvement with initial management, or if suspicious of inhaled foreign body, epiglottitis,

May reveal ‘steeple sign’ – subglottal narrowing of airway. But CXR findings not specific, nor always present.

TREATMENT

Mild

Oral dexamethasone single dose of 0.6mg/kg

Can go home with croup advice (ie red flag signs of deterioration)

Do not need a period of observation

Moderate

Oral dexamethasone single dose of 0.6mg/kg

Observation needed for at least 2 hrs – home with advice if completely settled

If worsening – nebulized adrenaline 2mls of 1:1000 and further observation needed

Can use nebulized budesonide 2mg.

Severe

PO/IV dexamethasone 0.6mg/kg

Oxygen by facemask/nasal cannula if child tolerates

Nebulised adrenaline 2ml of 1:1000 to be repeated as often as every hour if needed but close monitoring required.

Repeated nebulized budesonide if responsive

Admission as inpatient.

Close monitoring

Consider anaesthetic review if deterioration and needing intubation/surgical airway

Antibiotics do not need to be routinely started, unless there is doubt as to diagnosis of croup (e.g. suspecting tracheitis/ epiglottitis) or poor response to initial therapy.

Supportive care:

Need to keep the child calm, avoid disturbance as much as possible.

Encourage breastfeeding and oral fluids.

Avoid IV fluids/cannula if not necessary as this can cause the child more distress and increase symptoms.

Dr Y Zhou Nov 2014.

References:

WHO Hospital care for children 2013 edition

NHS guidelines for management of croup

www.patient.co.uk