Coronary Heart Disease (CHD) s1

Suppl. Table 3. Stepwise logistic regression analysis. Dependent variable: treatment with statins, including the association with ezetimibe

Variable / B / SE / Odds
Ratio / Lower
95%CI / Upper
95% CI / p-value
Step 1
(a) / Polypharmacy % (≥ 5 drugs) / 1.395 / .130 / 4.034 / 3.125 / 5.207 / <0.001
Constant / -2.239 / .115 / .107 / <0.001
Step 2
(b) / Polypharmacy % (≥ 5 drugs) / 1.383 / .132 / 3.986 / 3.077 / 5.162 / <0.001
Dyslipidemia / 1.261 / .161 / 3.531 / 2.578 / 4.836 / <0.001
Constant / -2.383 / .119 / .092 / <0.001
Step 3
(c) / Polypharmacy % (≥ 5 drugs) / 1.241 / .135 / 3.459 / 2.654 / 4.508 / <0.001
Dyslipidemia / 1.214 / .162 / 3.368 / 2.451 / 4.629 / <0.001
Previous CHD event / .633 / .120 / 1.884 / 1.488 / 2.385 / <0.001
Constant / -2.462 / .121 / .085 / <0.001
Step 4
(d) / Polypharmacy % (≥ 5 drugs) / 1.219 / .135 / 3.384 / 2.595 / 4.414 / <0.001
Dyslipidemia / 1.211 / .163 / 3.356 / 2.438 / 4.618 / <0.001
Previous CHD event / .590 / .122 / 1.803 / 1.421 / 2.289 / <0.001
Peripheral vascular disease / .490 / .148 / 1.633 / 1.221 / 2.182 / 0.001
Constant / -2.511 / .122 / .081 / <0.001
Step 5
(e) / Total cholesterol / -.004 / .001 / .996 / .994 / .999 / 0.006
Polypharmacy % (≥ 5 drugs) / 1.177 / .136 / 3.245 / 2.484 / 4.239 / <0.001
Dyslipidemia / 1.285 / .166 / 3.616 / 2.611 / 5.009 / <0.001
Previous CHD event / .568 / .122 / 1.765 / 1.389 / 2.242 / <0.001
Peripheral vascular disease / .474 / .149 / 1.606 / 1.200 / 2.150 / 0.001
Constant / -1.903 / .250 / .149 / <0.001
Step 6
(f) / Total cholesterol / -.004 / .001 / .996 / .994 / .999 / 0.004
Polypharmacy % (≥ 5 drugs) / 1.123 / .138 / 3.074 / 2.346 / 4.029 / <0.001
Dyslipidemia / 1.265 / .166 / 3.544 / 2.558 / 4.910 / <0.001
Hypertension / .374 / .157 / 1.454 / 1.070 / 1.976 / 0.017
Previous CHD event / .549 / .123 / 1.731 / 1.362 / 2.201 / <0.001
Peripheral vascular disease / .456 / .149 / 1.578 / 1.178 / 2.113 / 0.002
Constant / -2.132 / .270 / .119 / <0.001
Step 7
(g) / Age / -.020 / .008 / .980 / .965 / .995 / 0.011
Total cholesterol / -.004 / .001 / .996 / .994 / .999 / 0.005
Polypharmacy % (≥ 5 drugs) / 1.137 / .138 / 3.118 / 2.377 / 4.090 / <0.001
Dyslipidemia / 1.229 / .167 / 3.416 / 2.461 / 4.742 / <0.001
Hypertension / .402 / .157 / 1.496 / 1.099 / 2.034 / 0.010
Previous CHD event / .573 / .123 / 1.773 / 1.392 / 2.259 / <0.001
Peripheral vascular disease / .466 / .150 / 1.593 / 1.188 / 2.136 / 0.002
Constant / -.578 / .667 / .561 / 0.386

Coronary Heart Disease (CHD)

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