SUMMER 07/23/08

BMES 212: The Body Synthetic

Class meets T,Th 9:30 – 10:50 CAT 76

Credits: 3.0

Dr. T. , Office: 7-614-1 Tel: 215.895.1650

Dr. Peter Lelkes: ffice: 7-707 Tel: 215.895.2219

Dr. M. Wheatley: ffice: 27-A48Tel: 215-895 2232

TAs:

Crissy McDonald

JingjiaHan

Library Resources help: Jay Bhatt: agerty library

Web support : David Tristano:

Course Description: Body Synthetic introduces underlying biological and engineering principles involved in the design and construction of prosthetic devices used to replace various parts of the human body. Specifically, the course illustrates important advances in tissue engineering, the muskuloskeletal system, and the cavdiovascular system, as illustrative examples.

Goals for the Course: Biomedical engineers of tomorrow need to be familiar with fundamentals of engineering and biology. The course provides an overview of the interface between technology and biological sciences and introduces the student to the problems inherent at any such interface.Upon completion the student should be familiar with general principals of foreign body interactions and blood interactions, gain insight into tissue engineering and specific details of the musculoskeletal and cardiovascular systems as they pertain to the development and use of synthetic body parts. The student will also become familiar with literature searching in peer reviewed journals and good writing practices.

Week/dateInstructorTopicComments

106/24MAWTissue Engineering

106/26MAWTissue Engineering

207/1MAW/DTIntro to WEB: Tissue EngineeringDavid Tristano

207/03MAWTissue Engineering

307/08MAWTissue Engineering`

307/10MAWTissue EngineeringPersonal web page due

407/15TDQuiz 1/BiomechanicsQuiz 1

407/17TDBiomechanics

507/22PLCardiovascular

507/24 PLCardiovascular

607/29PLCardiovascular DECISION ON TOPIC

607/31PLCardiovascularHomework, web pages

708/05PLCardiovascular

708/07TDCardiovascularHomework, web page

808/12TDQ2/BiomechanicsQuiz 2

808/14TDBiomechanicsHomework, web pages

908/19TDBiomechanics

908/21TDBiomechanicsWeb page due midnight Sunday

1008/26Presentations

1008/28Presentations

11EXAM WEEKQuiz 3

Course structure: Lectures will involve instruction on the three core disciplines. One main requirement in this course will be to show proficiency at least in one core discipline by constructing a webpage on a specific topic related to the discipline. You may choose a topic from the three main thrusts of this course, Tissue engineering, Cardiovascular and biomedical mechanics. The selected topic must be approved by instructor. Mr. David Tristano from IRT will give you an introductory lecture on Web Page design during the second session of the course, and continue to advise you if needed. At the end of the course each group will present their webpage to the entire class.

Text: There is no assigned text. Use the peer-reviewed literature Handouts/ readings will be assigned by each instructor, Thefreeware applicationfor the web page is

Home work: Homework will be assigned by each instructor as best fits the section. You will be expected to be working on your web page, so homework will not be assigned on a regular basis

Web Pages: You are expected to use the peer-reviewed literature. This does not mean Google or Wikipedia!!

Plagiarism will be dealt with in the strongest terms, with an F assigned to the course.

The web page should contain references cited in the form illustrated below

Reference Samples:

Article: Pearson P.J., Schaff H.V. and Vanhoutte P.M. (1990) Longtermimpairment of endothelium-dependent relations to aggregatingplatelets after reperfusion in injury in canine coronary arteries. Circulation,81, 1921-1927.

Chapter in Edited Book: Griffith T.M., Edwards D.H. and RandalM.D. (1990) Blood flow and optimal vascular topography: Role of theendothelium. In Endothelial Mechanisms of Vasomotor Control (eds.H. Drexler, A.M Zeiher, E. Bassenge and H. Just), Steinkopff VerlagDarmstadt, pp. 89-96.

Book:Rubanyi G.M. (1991) Cardiovascular Significance of Endothelium-Derived Vasoactive Factors. Futura Publishing Company, Inc., NewYork.

We have asked Mr. Jay Bhatt from the Hagerty Library to give you an introductory presentation in the second session of the first week of the course. Mr. Bhatt has been extremely helpful to faculty and students and if you need help with library/information issues, please do not hesitate to contact him (Bhatt, Jay J Mr215.895.1873 ).

Quizes:There will be three quizzes; one on each thrust area according to the schedule

Presentations: Students in their assigned groups of ±4 students, and will jointly present a 20 minute presentation on their web cite. The individual responsible for a given section will walk the audience through that section. Grades will be assigned as a group grade for the presentation equal to 35% and individual grade based on group student self evaluation (forms will be sent out) of each other member of the group.

Presentations: Students in their assigned groups of 4/5students, will jointly present a 20 minute presentation on their web site. The individual responsible for a given section will walk the audience through that section. Grades will be assigned per group for the presentation equal to 25% individual grade based on group self evaluation 15% (forms will be sent out) of each othergroup member.

Attendance will be taken at all classes and at all the presentations; every student is expected to attend. every class and every presentation Your grade will drop for each presentation day you miss.

Overall Grading Policy

Quizes: 3x3x15%

Homework15%

Web pageGroup evaluation25%

Individual (Peer evaluation)15%

Total100%