BIOL 4753, Human Molecular Genetics, Spring2014

Class: 215 Williams Hall, 3:00PM-6:00PM (Tuesdays)

Textbook: Strachan & Read, Human Molecular Genetics, 4th ed. (2010)

Course Director: Prof. Mark Batzer, 643 LSA, x8-7102, ,

UTA: Catherine Fontenot, 653 LSA, x8-7104,

DATE:LECTURE TOPICS:

January 21, 2014Lecture 1: DNA Structure and chromosomes

January 28, 2014Lecture 2: Genes in pedigrees, cloning

February 4, 2014Lecture 3: Cloning cont., hybridization assays

February 11, 2014Lecture 4: PCR, sequencing

February 18, 2014Lecture 5: Human genome organization, exam review

February 25, 2014Exam 1 (40%)

March 4, 2014Mardi Gras Holiday (No class)

March 11, 2014Lecture 6: Exam feedback

March 18, 2014Lecture 7: Human gene expression

March 25, 2014Lecture 8: Instability of the human genome

April 1, 2014Lecture 9: Physical and genetic mapping, complex diseases

April 8, 2014Lecture 10: Mobile elements, genome projects, evolution

April 15, 2014Spring Break (No class)

April 22, 2014Lecture 11: Identifying human genes, forensics

April 29, 2014Lecture 12: Research literature discussion, exam review

May 5, 2014Exam 2 (40%) Monday 3:00 – 5:00PM

Exams:Exams 1 and 2 will each count for 40% of the final grade (80% total). The second exam (Final) will be cumulative. The remaining 20% of the grade will come from the preparation and discussion of original research literature article outlines. The research outlines are due at the beginning of class on March 25th, 2014. The final/revised versions of the research outlines are due on April 22nd. Graduate credit will be earned through the completion of additional essay examination questions. A single comprehensive make-up exam will be given May 6th to those students with excused absences from the exam during the semester. During the examination all electronic devices (including cell phones and smart phones) must be put away. Students with an electronic device out may be referred to the Dean of Students. Having the device out during the examination is a violation of the test conditions.

Expectations: This is a 3-hour credit course. You will need to spend at least 6 hours out of class each week reading assignments, writing a research paper, studying lecture notes, and preparing for examinations to do well in the course.

Grading: A, 100-90%; B, 89-80%; C, 79-70%; D, 69-60%; F 59% and lower.