Assignment 18.3 Front Sheet

Learner name / Target / Assessor name
Mrs Turner-Smith
Date issued / Completion date / Submitted on
16/11/2015 / 17/12/2015
Unit number and title
Unit 18: Genetics and genetic engineering
Assignment title / Mendelian Genetics
In this assessment you will have opportunities to provide evidence against the following criteria.
Criteria reference / To achieve the criteria the evidence must show that the learner is able to: / Task No. / Evidence
Pass P5 / Explain monohybrid and dihybrid inheritance ratios
Reebops / 1
Key terms in inheritance / 2
Investigating inheritance in drosophila / 3
Merit M3 / Apply principles of modern Mendelian genetics to predict patterns of monohybrid, dihybrid inheritance and variation.
Key terms in inheritance / 2
Investigating inheritance in drosophila / 3
Genetics workbook / 4
Distinction D2 / Analyse the correlation between observed pattern of dihybrid inheritance pattern and the expected pattern.
Investigating inheritance in drosophila / 3
Worksheet on Chi-Squared Analysis / 5
Learner declaration
I certify that the work submitted for this assignment is my own and research sources are fully acknowledged.
Learner signature: / Date:

Assignment 18.3 Brief

Qualification / BTEC Level 3 Subsidiary Diploma in Applied Science (Applied Biology)
Unit number and title / Unit 18: Genetics and genetic engineering
Start date / 16/11/2015
Deadline / 17/12/2015
Assessor name / Mrs Turner-Smith
Assignment title / Mendelian Genetics
The purpose of the assignment is to understand the principles of classical genetics and
Mendel’s laws of inheritance and modern genetics.
Scenario
You are about to start work in a molecular biology lab and have been asked to demonstrate your understanding of classical genetics.
Task 1 / P5: Explain monohybrid and dihybrid inheritance ratios
Reebops are imagined animals. They have 16 chromosomes (in 8 homologous pairs) in their body cells.
Have a look at the parents – Mum and Dad Reebop. Note their characteristics, such as number of body segments, antennae etc. Both parents have the same features, but one is male and one is female. Follow the instructions to show an understanding of what happens when organisms breed and how it leads to variation.
Due date: This provides evidence for P5
Task 2 / P5: Explain monohybrid and dihybrid inheritance ratios / M3: Apply principles of modern Mendelian genetics to predict patterns of monohybrid, dihybrid inheritance and variation.
On the worksheet that you have been given give the meanings of the key inheritance terminology including:
√Homologous Chromosome
√Locus
√Allele
√Carrier
√Genotype
√Phenotype
√Homozygous
√Heterozygous
√Dominant allele
√Recessive allele
√Monohybrid inheritance
√Di-hybrid inheritance
√F1 Generation
√F2 Generation
√Sex-linked
√Co-dominance
√Multiple alleles
Due date: This provides evidence for P5 + M3
Task 3 / P5: Explain monohybrid and dihybrid inheritance ratios / M3: Apply principles of modern Mendelian genetics to predict patterns of monohybrid, dihybrid inheritance and variation. / D2: Analyse the correlation between observed pattern of dihybrid inheritance pattern and the expected pattern.
Using the computer simulation you are going to complete an investigation looking at dihybrid inheritance in the fruit fly drosophilia melongaster. You are going to focus on two mutations and use your knowledge of inheritance to complete the workbook on inheritance and a carry out statistical analysis to inform your conclusion.
Remember to reference any of your information that you have used.
Due date: This provides evidence for P5, M3, D2
Task 4 / M3: Apply principles of modern Mendelian genetics to predict patterns of monohybrid, dihybrid inheritance and variation.
Complete the workbook on genetic problems. The workbook requires you to demonstrate an understanding of the following:
√Monohybrid inheritance
√Di-hybrid inheritance
√Co-dominance
√Lethal alleles
√Sex-linkage
Due date: This provides evidence for M3
Task 5 / D2: Analyse the correlation between observed pattern of dihybrid inheritance pattern and the expected pattern.
Complete the worksheet to demonstrate your understanding of monohybrid and dihybrid inheritance and calculate the difference between the observed and expected value for each example.
Due date: This provides evidence for D2
Evidence checklist
[Summarise evidence required, e.g. ‘leaflet’, ‘presentation notes’ etc.] / [tick boxes]
Reebops
Key terms in inheritance
Investigating inheritance in drosophila
Genetics workbook
Worksheet on Chi-Squared Analysis
Sources of information
Adds J, Larkcom E and Miller R – Genetics, Evolution and Biodiversity (Nelson Advanced Science: Biology Series) (Nelson Thornes Ltd, 2004) ISBN 9780748774920
Adds J, Larkcom E and Miller R – Molecules and Cells (Nelson Advanced Science: Biology Series)
(Nelson Thornes Ltd, 2003) ISBN 9780748774845
Giddings G, Jones N and Karp A – The Essentials of Genetics (Hodder Murray, 2001) ISBN 9780719586118
Association of the British Pharmaceutical Industry
Biology simulations and exercises
DNA interactive
Gene Almanac DNA animations
National Centre for Biotechnology Education
Method for extraction of DNA from onions
Beginner’s guide to molecular biology
DNA interactive
This brief has been verified as being fit for purpose
Assessor / Mrs N Turner-Smith
Signature / Date / 06/07/2015
Internal verifier / Ms Fensome
Signature / Date / 06/07/2015
Assessor's comments
Qualification / BTEC Level 3 Subsidiary Diploma in Applied Science / Assessor name / Mrs Turner-Smith
Unit number and title / Unit 18: Genetics and Genetic Engineering / Learner name
Criteria reference / To achieve the criteria the evidence must show that the learner is able to: / Achieved?
P5 / Explain monohybrid and dihybrid inheritance ratios
M3 / Apply principles of modern Mendelian genetics to predict patterns of monohybrid, dihybrid inheritance and variation.
D2 / Analyse the correlation between observed pattern of dihybrid inheritance pattern and the expected pattern
Learner feedback
Assessorfeedback
Assessor signature / Date
Learner signature / Date