1985 Bsc (1St Class Hons) Pharmacy, QUB

4

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PERSONAL INFORMATION Pro-Vice-Chancellor (Education and Students) Queen’s University Belfast (QUB), Vice-Chancellor’s Office, 1 University Road, Belfast BT7 1NN; Tel, (028)90975132; Email,

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EDUCATION

1985 BSc (1st Class Hons) Pharmacy, QUB

1988 PhD (Pharmaceutics)

2006 DSc (Biomaterials)

2014 BA (1st Class Hons) Mathematics and Statistics, Open University;

EMPLOYMENT

1988-92 Lecturer Pharmaceutical Technology, University of Otago, NZ

1992-94 Head of Formulations, Norbrook Laboratories, Newry, Northern Ireland

1994-97 Lecturer in Pharmaceutics, School of Pharmacy, QUB

1997-1999 Senior Lecturer in Pharmaceutics, QUB

1999-present Professor of Biomaterials Sciences, QUB

2010-2014 Director of Education, School of Pharmacy, (35 Full-time Academic Staff) QUB

2009-2013 Royal Society Industrial Fellow

2011-2012 Acting Head of School of Pharmacy, QUB

2014-present Pro-Vice-Chancellor (Education and Students), QUB

AWARDS

1985 QUB Foundation Award

1997 Eli Lilly Award for Pharmaceutical Excellence

1997 British Pharmaceutical Conference Science Medal Award;

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ADMINISTRATION (QUB)

2003-present Director of the Medical Devices Research Group

2010-present Member of Academic Council of QUB

Member of Academic Board of QUB

Member of the Honorary Degrees Committee of QUB

Member of the Planning and Finance Group of QUB

Member of the Health and Safety Management Group of QUB

2012-present Member of Senate, QUB

2013-present Member of the Membership Committee for Senate of QUB

2014-present Pro-Vice-Chancellor (Education and Students)

2014-present Member of the Council of Legal Education QUB

2014-present Member of the Board of Governors, St. Mary’s College, QUB;

ADMINISTRATION (EX-QUB)

2010-present Member of the Statistics Advisory Committee for Northern Ireland

2008-2010 Chair Pharmacy category Undergraduate Awards for Ireland

2010-2011 Chair Medical Sciences category Undergraduate Awards of Ireland

2007-present Member of the Board of Governors for Belfast Royal Academy

2008-present Member of the Board of Governors of the Royal School Dungannon

2012-present Council Member of the Pharmaceutical Society of Northern Ireland

2013-present Vice-Chairman of the Board of Governors of the Royal School Dungannon

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TEACHING/INSTRUCTION

Undergraduate courses: Pharmaceutical Engineering, Statistics

Postgraduate courses: Medical Statistics

Postgraduate students: 36 PhDs completed; 12 current PhDs; 6 PDRAs completed; 2 current PDRAs

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RESEARCH GRANTS

Through the duration of my research career, >£11M has been attracted from a range of sources (Government, EPSRC, BBSRC, Pharmaceutical and Medical Device Industries).

Exemplar grants include:

2012 – 2015 Department of Trade and Industry/Invest NI Enhanced solubility of BCS Class 2 drugs using Hot Melt Extrusion (£315,155)

2011–2013 Rovi Pharmaceuticals Development of Multilayered Urinary Catheters with improved resistance to infection (£274,373)

2011-2014 CIBA Vision Sensitizer-incorporated contact lenses (£132,790)

2010-2011 Blue Highway Antimicrobial polymers (£57,971)

2010-2013 Engineering and Physical Sciences Research Council Microneedle-mediated enhanced Raman therapeutic drug monitoring (£327,441)

2010-2013 Engineering and Physical Sciences Research Council Light-triggered precision drug dosing from PVC endotracheal tube biomaterials (£371,378)

2010-2011 CIBA Vision Lens care products incorporating sensitizers (£186,919)

2009-2013 Royal Society Industrial Fellowship Enhanced solubility of BCS Class 2 drugs using hot melt extrusion (£156,018)

2008-2009 Invest Northern Ireland Proof of Concept Infection-resistantcontact lenses and intraocular lenses (£80,000)

2008-2009 Invest Northern Ireland Proof of Concept Photodynamic protection of surfaces: Control of healthcare-associated infection (£76,460)

2008–2011 Department of Trade and Industry/Invest Northern Ireland/ Biology and Biological Sciences Research Council. Novel antimicrobial polymeric implants (£124,497)

2007-2010 Engineering and Physical Sciences Research Council Surface-active gels as next generation chemical sensors (£218,890)

2005-2008 Gates Foundation £564k, Wellcome Trust £656k Grand Challenges in Global Health' Programme: vaginal HIV vaccines (£1.22M)

2005-2008 Department of Trade and Industry/Engineering and Physical Sciences Research Council Design, development and characterisation of novel biomaterials for use as high performance ocular medical devices (£302,000)

2004-2006 Invest Northern Ireland Proof of Concept Bioactive Composite Biomaterials (£121,000)

2003-2006 Engineering and Physical Sciences Research Council Synthesis, characterisation and performance of novel porphyrin-incorporated intraocular lens biomaterials (£241, 676)

2002-2005 EU Programme Peace and Reconciliation RTD Centre of Excellence, Medical Polymer Research Institute (£2.26M)

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CONFERENCE Session Chair/WORKSHOP COORDINATOR/CONFERENCE ORGANISER:

Chair, Silicone Elastomers (2005), British Pharmaceutical Conference Materials Science Section (2004-2008), Academy of Pharmaceutical Sciences (2009, 2010), Amorphous Materials (Amsterdam 2009), Amorphous III (Nottingham 2010)

Conference Organiser, Medical Polymers (Dublin 2004); Poorly Soluble Drug Compounds: Formulating Solid solutions (Chicheley Hall, Bucks 2013)

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EXEMPLAR INVITED PRESENTATIONS

2014:

(1) Understanding and Controlling/Optimising Drug-Polymer Interactions for Drug Delivery and Medical Device Applications Keynote address at the Polymers in Drug Delivery, Philadelphia, US.

2013:

(2) Stimulus Sensitive Biomaterials: Strategies to Enhance Clinical Performance Keynote address at the 15th Formulation and Delivery of Bioactive Conference Dunedin, New Zealand

(3) Polymeric Strategies to Enhance Medical Device Performance Keynote address at the Australasian Pharmaceutical Sciences Conference Dunedin, New Zealand

(4) Engineering the performance of biomaterials through understanding and optimisation of their viscoelastic properties, Keynote address at the Nordic Rheology Conference, Copenhagen

2012:

(5) Light-activated antimicrobial biomaterials, Keynote address to CIMEC 4th International Conference on Smart Materials, Structures and Systems (Milan)

(6) Design and performance of rheological structured bioactive implants, Keynote address to the International Symposium of Pharmaceutical Sciences (Ankara)

2011:

(7) Enhanced solubility of poorly soluble drugs using hot melt extrusion, Innovations in Controlled Release, Berlin

2009:

(8) Engineering the solid state using thermal processing methods. Keynote address to ADMET (Berlin)

2008:

(9) Hot melt processing of pharmaceutical solid dosage forms: Opportunities for engineering the solid state and drug release properties. Keynote address to Amorphous Materials, Amsterdam

(10) Engineering drug delivery using polymer extrusion/injection moulding technologies. Keynote address at the British Pharmaceutical Conference (Manchester)

(11) New strategies for achieving controlled release of bioactive agents Keynote address at the 10th Formulation and Delivery of Bioactive Conference Dunedin, New Zealand

2007:

(12) Engineering drug delivery using polymer extrusion/injection moulding technologies Keynote address at Pharmaceutical Materials Conference, Basle

2006:

(13) Advanced Silicones for Improved Medical Device Performance Keynote address to Silicone Elastomers, Frankfurt

2005:

(14) Advances in medical device polymer performance Keynote address to The Surface Engineering of Polymers Conference, Dublin

(15) Engineered drug delivery from bioactive biomaterials Keynote address to Emerging Technologies in Medical Polymers: Theory and Applications, Belfast

2004:

(16) Optimisation of the clinical performance of medical devices using advanced polymeric biomaterials Keynote address to Medical Polymers Dublin

(17) Tipping the biological balance: Advanced anti-infective biomaterials for medical device applications Keynote address to The 10th International Conference on Polymers in Medicine and Surgery, Cambridge

2003:

(18) Making biomaterials work: Novel biomaterials for enhanced medical device performance Keynote address to The Second International Conference for Bioactive Materials, Cardiff

2002:

(19) How does it feel? Textural analysis of pharmaceutical systems Keynote address to The Making Sense of the Senses Conference, London

2001:

(20) Design, characterisation and clinical performance of bioadhesive drug delivery systems within the oral cavity Key note address to The 3rd Conference on Bioadhesion, Portsmouth

2000:

(21) Ventilator-associated pneumonia: The biological catch 22 Key note address to the Society for General Microbiology, Maynooth

(22) Sticky When Wet: Bioadhesive Drug Delivery Systems for the Treatment of Oral Disorders, Keynote address to the 19th Pharmaceutical Technology Conference, Baveno-Stressa

(23) Active and reactive systems: Addressing clinical needs through biomaterial design, Keynote address to the formulation division of the Royal Society of Chemistry, London

1999:

(24) Engineering clinical performance through biomaterial design Keynote address to the Australasian Formulation and Drug Delivery Conference, Dunedin, New Zealand

1998:

(25) Advanced polymeric biomaterials: clinical panacea or modern dilemma Keynote address to the British Pharmaceutical Conference, Eastbourne

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EDITORIAL BOARDS/AD HOC REVIEWER; REFEREE; EXAMINER

Editor: The Journal of Pharmacy and Pharmacology (2000-present)

Co-Editor: Drug Delivery (2009-present)

Editorial Board Member:

Journal of Pharmaceutical Sciences (2010-present)

Therapeutic Delivery (2010-present)

Open Drug Delivery Journal (2011-present)

Open Biomedical Engineering Journal (2011-present)

Journals for which I am a Reviewer–Pharmaceutical Research, J. Controlled Release, Biomaterials, Eur. J. Pharmaceutics Biopharmaceutics, Eur. J. Pharmaceutical Sciences, Int. J. Pharmaceutics, Acta Biomaterialia, Soft Materials, J. Biomedical Materials Res., J. Materials Science: Materials in Medicine. J. Colloid Interfacial Science

2003-2007 External examiner (BPharm) UCC

2004-2010 External examiner (MSc Industrial Pharmacy), RCSI

2005-2009 External examiner (MPharm), University of Hertford

2006-2010 External examiner (BPharm), RCSI

2012-present External examiner (MPharm), University of Durham

2013-present External examiner (MPharm), University of Brighton

2014-present External examiner (MPharm), Trinity College Dublin

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LEARNED SOCIETY POSITIONS

1989

Member of the Pharmaceutical Society of Northern Ireland

Member of the Pharmaceutical Society of New Zealand

1998

Member of the Royal Society of Chemistry

2000 Fellow of the Royal Statistical Society

2001 Fellow of the Institute of Materials, Minerals and Mining

2007 Member of the Institute of Engineers in Ireland

2013 Elected Fellow of the Pharmaceutical Society of Northern Ireland

Chartered Chemist (1998)

Chartered Engineer (2001)