12Th SCBA International Symposium

12th SCBA International Symposium

Program

Date / Time / Room / Session / Speakers /
6/14 / 15:30-17:30 / 2 / 14A / Genomic medicine: Y chromosome, germ cell & gonad development
Co-charis: Wai-Yee Chan (National Institutes of Health, Bethesda)
Pauline Yen (Academia Sinica, Taipei)
6/14 / 15:30-16:00 / 2 / 14A-1 / Yun-Fai Chris Lau (University of California at San Francisco, San Francisco)
Mammalian sex determination. The conflicts between SRY and R-Spondin 1.
6/14 / 16:00-16:30 / 2 / 14A-2 / Pao-Lin Kuo (National Cheng Kung University College of Medicine, Tainan)
Regulatory single nucleotide polymorphisms of DAZL and BOULE confers susceptibility to spermatogenic defect in Taiwanese men.
6/14 / 16:30-17:00 / 2 / 14A-3 / Yi-Wen Lin (Academia Sinica, Taipei)
USP26 at the tip of mouse sperm head is required for fertilization.
6/14 / 17:00-17:30 / 2 / 14A-4 / Wai-Yee Chan (National Institutes of Health, Bethesda)
Pseudogene-derived antisense transcripts in male germ cells.
6/14 / 15:30-17:30 / CH / 14B / Environmental carcinogenesis and cancer prevention
Co-chairs: Moon-Shong Eric Tang (New York University School of Medicine, Tuxedo)
Tom K. Hei (Columbia University, New York)
6/14 / 15:30-15:50 / CH / 14B-1 / Moon-Shong Eric Tang (New York University School of Medicine, Tuxedo)
Searching for the true villains of lung and liver cancer: finger printing DNA damage in the p53 gene.
6/14 / 15:50:16:10 / CH / 14B-2 / Tom K. Hei (Columbia University, New York)
Environmental radon: the non-targeted effects and cancer risk.
6/14 / 16:10-16:30 / CH / 14B-3 / Chung S. Yang (The State University of New Jersey, Piscataway)
Prevention of environmental carcinogenesis by tocopherols and tea polyphenols.
6/14 / 16:30-16:50 / CH / 14B-4 / Fung-Lung Chung (Georgetown University Medical Center, Washington)
Cancer prevention by cruciferous vegetable-derived isothiocyanates: a mechanism study.
6/14 / 16:50-17:10 / CH / 14B-5 / Burton Yang (Sunnybrook Research Institute, Toronto)
MicroRNA functional analysis and target identification in vitro and in vivo.
6/14 / 17:10-17:30 / CH / 14B-6 / Chien-Jen Chen (Academia Sinica, Taipei)
Multiplicity of cancers induced by ingested arsenic: an environmental pandemic.
6/14 / 15:30-17:30 / 1 / 14C / New drug development and therapeutics
Co-chairs: Richard Zhao (University of Maryland Medical Center, Baltimore)
Jennifer Jing-Shan Hu (Merck & Co., Inc., Whitehouse Station)
6/14 / 15:30-16:00 / 1 / 14C-1 / Jian Ni (Human Antibodomics (SIP) Inc., Suzhou)
Novel antibody drug development challenges in China: how to identify novel antibody target and lead.
6/14 / 16:00-16:30 / 1 / 14C-2 / James Li (Cellex Inc., Rockville)
A real time neuraminidase assay for sensitive influenza diagnosis and drug resistance testing.
6/14 / 16:30-17:00 / 1 / 14C-3 / Patrick Lu ( Sirnaomics, Inc., Gaithersburg)
Multi-targeted siRNA therapeutics: a new paradigm of targeted medicine.
6/14 / 17:00-17:30 / 1 / 14C-4 / Peter M. Qian (Reviva Biopharmaceutics LLC, Gaithersburg)
The opportunity of follow-on biologics (biogenerics) in China.
6/15 / 8:30-9:15 / CH / Opening / Robert Yu (President, SCBA)
Chi-Huey Wong (President, Acedemia Sinica)
Kenneth K. Wu (President, National Health Research Institutes)
Andrew H.-J. Wang (Vice President, Acedemia Sinica)
6/15 / 9:15-10:00 / CH / Keynote / 2009 SCBA Presidential Awardee
Robert Tjian (Howard Hughes Medical Institute)
Switching core transcription machinery: Am unexpected mechanism for maintaining stem cell pluripotency and driving differentiation.
Chair: Andrew H.-J. Wang (Academia Sinica)
6/15 / 10:30-12:30 / CH / 4D / Targeted cancer therapy for personalized cancer care: from bench to bedside
Chair: Dihua Yu (The University of Texas M.D. Anderson Cancer Center, Houston)
6/15 / 10:30-10:54 / CH / 4D-1 / Richard Jove (City of Hope Cancer Center, Duarte) will not be able to come
Targeting JAK-STAT signaling for cancer therapy.
6/15 / 10:54-11:18 / CH / 4D-2 / Jin Q. Cheng (H. Lee Moffitt Cancer Center & Research Institute, Tampa)
Targeting the PI3K-AKT-mTOR pathway as a novel therapeutic approach in human cancer.
6/15 / 11:18-11:42 / CH / 4D-3 / Guangbiao Zhou (Chinese Academy of Sciences, Guangzhou)
Targeted therapy for cancer: from protein modification and degradation to medication.
6/15 / 11:42-12:06 / CH / 4D-4 / Dihua Yu (The University of Texas M.D. Anderson Cancer Center, Houston)
Combinational targeted therapies for HER2-overexpressing and PTEN-deficient breast cancer.
6/15 / 12:06-12:30 / CH / 4D-5 / Wen-Hwa Lee (University of California at Irvine, Irvine)
Development of small molecule compounds targeting tumor suppressor networks.
6/15 / 10:30-12:30 / 1 / 5C / Chromatin epigenetic modification and cancer
Co-chairs: Chuxia Deng (National Institutes of Health, Bethesda)
Keji Zhao (National Institutes of Health, Bethesda)
6/15 / 10:30-10:50 / 1 / 5C-1 / Keji Zhao (National Institutes of Health, Bethesda)
Dynamic changes in histone modifications during differentiation.
6/15 / 10:50-11:10 / 1 / 5C-2 / Yang Shi (Harvard Medical School, Boston)
Histone methylation regulation and X-linked mental retardation.
6/15 / 11:10-11:30 / 1 / 5C-3 / Yue Xiong (University of North Carolina at Chapel Hill, Chapel Hill)
Control of stem and progenitor cell cycle by INK4 genes.
6/15 / 11:30-11:50 / 1 / 5C-4 / Chuxia Deng (National Institutes of Health, Bethesda)
BRCA1 and its downstream gene, SIRT1, in genetic instability, and cancer.
6/15 / 11:50-12:10 / 1 / 5C-5 / Paul Liu (National Institutes of Health, Bethesda)
Transcriptional regulation in normal and leukemia stem cells.
6/15 / 12:10-12:30 / 1 / 5C-6 / Ying E. Zhang (National Institutes of Health, Bethesda)
TGF-beta signaling and cancer.
6/15 / 10:30-12:30 / 2 / 8A / Mechanism and regulation
Chair: Linheng Li (Stowers Institute for Medical Research, Kansas)
6/15 / 10:30-10:54 / 2 / 8A-1 / Ting Xie (Stowers Institute for Medical Research, Kansas City)
Stem cells: Niche, competition, aging and applications.
6/15 / 10:54-11:18 / 2 / 8A-2 / Cheng-Ming Chuong (University of Southern California, Los Angeles)
Regulating skin stem cells: evolution, alopecia, and hair regeneration after wounding.
6/15 / 11:18-11:42 / 2 / 8A-3 / Weimin Zhong (Yale University, New Haven)
Asymmetric cell division and stem-cell homeostasis.
6/15 / 11:42-12:06 / 2 / 8A-4 / Chang-Zheng Chen (Stanford University School of Medicine, Stanford)
Stem cell microRNAs and their functions in self-renewal.
6/15 / 12:06-12:30 / 2 / 8A-5 / Hong Wu (University of California, Los Angeles)
PTEN and leukemic stem cells.
6/15 / 10:30-12:30 / 3 / 1C / Biofuel
Co-chairs: Jason C.H. Shih (North Carolina State University, Raleigh)
Tuan-Hua David Ho (Academia Sinica, Taipei)
6/15 / 10:30-11:00 / 3 / 1C-1 / Ming-Che Shih (Academia Sinica, Taipei)
Functional genomics of biomass conversion.
6/15 / 11:00-11:30 / 3 / 1C-2 / Tuan-Hua David Ho (Academia Sinica, Taipei)
Discovery and improvement of enzymes and microbes for lignocellulosic ethanol production.
6/15 / 11:30-12:00 / 3 / 1C-3 / Jason C. H. Shih (North Carolina State University, Raleigh)
Bio-methane and beyond.
6/15 / 12:00-12:30 / 3 / 1C-4 / Xu Cheng (China Agricultural Uiversity, Beijing)
Explore enterprise biogas industry, a case study of deriving biogas from high-concentrated organic wastewater.
6/15 / 13:30-15:30 / CH / 6D / Cognitive neuroscience
Chair: Nancy Ip (The Hong Kong University Science & Technology, Kowloon)
6/15 / 13:30-13:50 / CH / 6D-1 / Ann-Shyn Chiang (National Tsing Hua Unviersity, Hsinchu)
Three-dimensional reconstruction of wiring diagrams in the Drosophila brain.
6/15 / 13:50-14:10 / CH / 6D-2 / Jing W. Wang (University of California at San Diego, La Jolla)
The rules of attraction: neural circuit for olfactory behaviors in Drosophila.
6/15 / 14:10-14:30 / CH / 6D-3 / Joe Zhuo Tsien (Medical College of Georgia, Augusta)
The organizing principles of real-time memory encoding.
6/15 / 14:30-14:50 / CH / 6D-4 / Yu Tian Wang (University of British Columbia, Vancouver)
Hippocampal long-term depression and its role in learning and memory.
6/15 / 14:50-15:10 / CH / 6D-5 / Lin Chen (Chinese Academy of Sciences, Beijing)
The global-first topological definition of perceptual objects and the neural correlation of object representation in anterior temporal lobe and amygdale.
6/15 / 15:10-15:30 / CH / 6D-6 / Guosong Liu (TsingHua University School of Medicine, Beijing)
Reconfiguration of synaptic network and enhancement of memory by magnesium Ion.
6/15 / 13:30-15:30 / 1 / 5A / Environmental epigenetics and cancer susceptibility
Co-chairs: Juliann G. Kiang (Uniformed Services University of the Health Sciences, Bethesda)
Yu-Sun Chang (Chang Gung University, Taoyuan)
6/15 / 13:30-13:54 / 1 / 5A-1 / Juliann G. Kiang (Uniformed Services University of the Health Sciences, Bethesda)
Wound trauma enhances radiation-induced mortality: increases in iNOS, cytokines, and bacterial incidences.
6/15 / 13:54-14:18 / 1 / 5A-2 / Yu-Sun Chang (Chang Gung University, Taoyuan)
Epigenetic alterations of novel tumor suppressor genes in gaastric cancer and liver cancer.
6/15 / 14:18-14:42 / 1 / 5A-3 / Yi-Ching Wang (National Cheng Kung University, Tainan)
Tobacco carcinogen induces stabilization and accumulation of DNA methyltransferases 1 through AKT/hnRNP/bTrCP pathway in lung cancer.
6/15 / 14:42-15:06 / 1 / 5A-4 / Hsin-Pai Li (Chang Gung University, Taoyuan)
Hypermethylated genes in NPC.
6/15 / 15:06-15:30 / 1 / 5A-5 / Yu-Wei Leu (National Chung Cheng University, Chia-Yi)
Targeted DNA methylation in cell fate determination.
6/15 / 13:30-15:30 / 2 / 12A / Viral pathogenesis, anti-viral and anti-cancer therapies
Co-Chairs: Tzyy-Choou Wu (The Johns Hopkins University, Baltimore)
Richard Y. Zhao (University of Maryland Medical Center, Baltimore)
6/15 / 13:30-13:54 / 2 / 12A-1 / Tzyy Choou Wu (The Johns Hopkins University, Baltimore)
Innovative mechanisms for cancer immune evasion.
6/15 / 13:54-14:18 / 2 / 12A-2 / Richard Y. Zhao (University of Maryland Medical Center, Baltimore)
HIV-1 viral protein R as a novel agent for anticancer therapies.
6/15 / 14:18-14:42 / 2 / 12A-3 / Rongfu Wang (Baylor College of Medicine, Houston)
Regulatory T cells and innate signaling regulation in antiviral and cancer immunity.
6/15 / 14:42-15:06 / 2 / 12A-4 / Pei-Jer Chen (National Taiwan University, Taipei)
A novel mouse model for hepatitis B virus persistence.
6/15 / 15:06-15:30 / 2 / 12A-5 / Kuan-Teh Jeang (National Institutes of Health, Bethesda)
HTLV-1 and adult T-cell leukemia: mechanisitic insights into cellular transformation.
6/15 / 13:30-15:30 / 3 / 2A / Changing career leaderships between academia and industry
Chair: Tse-Wen Chang (Academia Sinica, Taipei)
6/15 / 13:30-13:50 / 3 / 2A-1 / Tse-Wen Chang (Academia Sinica, Taipei)
Anti-IgE for severe asthma and allergy: from concept to clinics to commercialization.
6/15 / 13:50-14:10 / 3 / 2A-2 / Jerome Shen (CX Ventures, Taipei)
The improving environment for professors to start companies.
6/15 / 14:10-14:30 / 3 / 2A-3 / Stanley Chang (Medigen Biotechnology Corp., Taipei)
Adventurous tour: the change of career track from surgeon to biotech CEO.
6/15 / 14:30-14:50 / 3 / 2A-4 / Dajun Yang (Morningside, Rockville)
From professor to entrepreneur: the landscape of investing in Chinese biotech companies.
6/15 / 14:50-15:10 / 3 / 2A-5 / Mei-Ling Chen (US FDA, Silver Spring) – Sponsored by Center for Drug Evaluation , Taiwan
Challenges and opportunities in the development of biosimilars or follow-on protein products.
6/15 / 15:10-15:30 / 3 / 2A-6 / Jennifer Jing-Shan Hu (Merck & Co., Inc., Whitehouse Station)
Partnering for success: the strategy for healthcare innovation by Merck & Co, Inc.
6/15 / 16:00-17:30 / CH / 8C / Disease and tissue regeneration
Chair: John Yu (Academia Sinica, Taipei)
6/15 / 16:00-16:30 / CH / 8C-1 / Yibin Wang (University of California at Los Angeles, Los Angeles)
Stress-signaling pathway in cardiac remodeling and regeneration.
6/15 / 16:30-17:00 / CH / 8C-2 / Zhigang He (Harvard Medical School, Boston)
mTOR and axon regeneration.
6/15 / 17:00-17:30 / CH / 8C-3 / Kenneth K. Wu (National Health Research Institutes, Miaoli County)
Prostaglandin biosynthesis and function in embryonic stem cells.
6/15 / 16:00-17:30 / 1 / 1B / Plant biology
Chair: Jen Sheen (Harvard Medical School, Boston)
6/15 / 16:00-16:22 / 1 / 1B-1 / Jen Sheen (Harvard Medical School, Boston)
Dual control of nuclear EIN3 by bifurcate MAPK cascades in C2H4 signaling.
6/15 / 16:22-16:44 / 1 / 1B-2 / Su-May Yu (Academia Sinica, Taipei)
Sugar cross-signalingnetwork in cereals.
6/15 / 16:44-17:06 / 1 / 1B-3 / Na-Sheng Lin (Academia Sinica, Taipei)
Trilateral interactions among virus, satellite RNA and host plants.
6/15 / 17:06-17:30 / 1 / 1B-4 / Tzyy-Jen Chiou (Academia Sinica, Taipei)
Phosphate homeostasis: role of miRNAs in long-distance signaling.
6/15 / 16:00-17:30 / 2 / 9A / Structural and mechanistic analysis of channel proteins and viruses
Chair: Wah Chiu (Baylor College of Medicine, Houston)
6/15 / 16:00-16:22 / 2 / 9A-1 / Ming-Ming Zhou (Mount Sinai School of Medicine, New York)
Modulating the modulator: epigenetic gene regulation beyond the histone code.
6/15 / 16:22-16:44 / 2 / 9A-2 / Wah Chiu (Baylor College of Medicine, Houston)
Seeing protein backbone and side-chains in molecular machines by single particle Cryo-EM.
6/15 / 16:44-17:06 / 2 / 9A-3 / Youxing Jiang (University of Texas Southwestern Medical Center, Dallas)
Structural analysis of a non-selective cation channel, NaK.
6/15 / 17:06-17:30 / 2 / 9A-4 / Yingfang Liu (Chinese Academy of Sciences, Beijing)
Crystal structure of avian influenza virus RNA polymerase proteins.
6/16 / 8:30–9:15 / CH / Keynote / Chi-Huey Wong (Academia Sinica, Taipei)
Post-translational glycosylation: Challenges and opportunities.
Chair: Robert Yu (SCBA President)
6/16 / 9:15-10:00 / CH / Keynote / 2009 SCBA Life-time Achievement Awardee
Jean Shih (University of Southern California, Los Angeles)
Understanding anxiety and impulsivity.
Chair: Ing Kang Ho (NHRI)
6/16 / 10:30-12:30 / CH / 4A / Prognostic and predictive biomarkers for Cancer
Chair: Pan-Chyr Yang (National Taiwan University College of Medicine, Taipei)
6/16 / 10:30-10:54 / CH / 4A-1 / Pan-Chyr Yang (National Taiwan University College of Medicine, Taipei)
Biomarker and personalized therapy for lung cancer.
6/16 / 10:54-11:18 / CH / 4A-2 / William Pao (Vanderbilt-Ingram Cancer Center, Nashville)
Targeting EGFR for cancer therapy: mechanisms of action and drug resistance.
6/16 / 11:18-11:42 / CH / 4A-3 / James Chih-Hsin Yang (National Taiwan University College of Medicine, Taipei)
Pharmacogenomics of EGFR as a predictive biomarker for lung cancer: what we have learned from clinical trials.
6/16 / 11:42-12:06 / CH / 4A-4 / Bangyan Li Stiles (University of Southern California, Los Angeles)