Unit 6 Review

1. Which of the following cannot alter a gene’s frequency in a

population?

a. inbreeding. d. migration.

b. mutation. e. a bottleneck.

c. random mating.

2. The frequency of the allele that causes sickle cell disease is

higher in some populations than in others because:

a. only black people can get sickle cell disease.

b. genetic testing is better now.

c. the incidence of malaria differs in different parts of the world.

d. the gene mutates at different frequencies in different parts

of the world.

e. heterozygotes are resistant to cholera.

3. Genetic engineering manipulates gene products at the level

of:

a. the protein. d. the polypeptide chain.

b. DNA. e. RNA.

c. amino acids.

4. Proteins isolated from bacteria that cut specific DNA

sequences are:

a. bacteriophage enzymes. d. restriction enzymes

b. telomerases. e. plasmids.

c. methylating enzymes.

5. A plasmid inside a bacterium makes the cell resistant to the

antibiotic drugs ampicillin and tetracycline. The plasmid DNA

is removed from bacteria and cut with a restriction enzyme,

which splits the tetracycline resistance gene and opens the

circle. A piece of foreign DNA is inserted into the now-open

restriction site. When the recombinant plasmid is inserted

into the bacterial cells, they will grow in the presence of:

a. neither drug. d. both drugs.

b. tetracycline only. e. ampicillin only.

c. More than one answer is correct.

6. A multicellular organism that carries a specific genetic change

in each cell, because of an intervention at the fertilized egg

stage, is a:

a. transformant. d. transition.

b. transgenic. e. transliterate.

c. transversion.

7. The enzyme used to “glue” each replication fragment in DNA

together is called:

a. a ligase enzyme. d. a replicon enzyme.

b. an endonuclease enzyme. e. an Ozaki enzyme.

c. a polymerase enzyme.

8. A mirror image found at certain sites in DNA are:

a. ligases. d. SNPs.

b. pyrimidines. e. nucleotides.

c. palindromes.

9. The process of running an electric current through agarose

in order to spread chromosome fragments is/are:

a. STRs d. electrophoresis.

b. RFLPs e. DNA electroplating.

c. VNTRs

10. When a recombined plasmid is inserted into the “host”

bacterial cell, this represents a(n):

a. vectorization. d. mutation.

b. recombination. e. replication.

c. transformation.

Answers

1. C 4. D 7. A 10. C

2. C 5. E 8. C

3. B 6. B 9. D