Yu, Mazet and Shimeld
The Fox gene complement of Branchiostoma floridae
Supplementary information
Alignments used in phylogenetic analyses.
Please see main text, Table 1 and Figures for full gene models and accession numbers.
1. Full Fox set for the molecular phylogenetic analysis shown in Figure 1. See main text and Figure 1 for gene models and accession numbers.
....|....| ....|....| ....|....| ....|....| ....|....| ....|....| ....|....| ....|....|
10 20 30 40 50 60 70 80
BfFoxAa_fg AYRRSYTHAK PPYSYISLIT MSIQSSPNKM VTLAEIYQFI MDLFPYYR-- ---QNQQRWQ NSIRHSLSFN DCFVKVPRT-
BfFoxAb_es QYRRSYTHAK PPYSYIALIT MAVQSSPNKM VTLSEIYQFI MDLFPFYR-- ---QNQQRWQ NSIRHSLSFN DCFVKVQRT-
BfFoxB CAD PGKDSYGNEK PPYSYISLTA MAIQSSGEKM LPLSDIYKFI MDRFPFYR-- ---QNTQRWQ NSLRHNL-FN DCFIKIPRR-
BfFoxAB-cD EEKGEDADTK PPYSYIALIV MALRSSPLGA LPLTGIYEFI ERTFPYFR-- ---RNKRRWQ NSIRHNLSLN DCFVKIPRS-
BfFoxC-CAH HTS--KDMVK PPYSYIALIA MAIQNAPDKK VTLNGIYQFI MDRFPYYR-- ---ENKQGWQ NSIRHNLSLN ECFIKVPRD-
BfFoxD_est VRKKS-NLVK PPYSYIALIT MSILQSPQKK LTLSQICEFI MNRFPYYR-- ---ERFPVWQ NSIRHNLSLN DCFVKIPRE-
BfFoxEa_es RRKRPVQKGK PPYSYIALIS MAIANSPERK LTLGGIYKFI MDRFPYYR-- ---DRDKKWQ NSIRHNLTLN DCFVKIPRE-
BfFoxEb_es RRRKQRPAGK PPYSYVALIT MAIVNSPERK TTLAGIYKFI MDHFPYYR-- ---EADKKWQ NSIRHNLTLN DCFVKLARH-
BfFoxEc_es RRRKQRPAGK PPYSYVALIT MAIVNSPERK TTLAGIYKFI MDHFPYYR-- ---EADKKWQ NSIRHNLTLN DCFVKLARH-
BfFoxEd_e- RRRKQRPAGK PPYSYVALIT MAIVNSPERK TTLAGIYKFI MDHFPYYR-- ---EADKKWQ NSIRHNLTLN DCFVKLARH-
BfFoxEe_e- RRRKQRPAGK PPYSYVALIT MAIVNSPERK TTLAGIYKFI MDHFPYYR-- ---EADKKWQ NSIRHNLTLN DCFVKLARH-
BfFoxEf_e- RRRKQRPAGK PPYSYVALIT MAIVNSPERK TTLAGIYKFI MDHFPYYR-- ---EADKKWQ NSIRHNLTLN DCFVKLARH-
BfFoxEg_e- RRRKQRPAGK PPYSYVALIT MAIVNSPERK TTLAGIYKFI MDHFPYYR-- ---EADKKWQ NSIRHNLTLN DCFVKLARH-
BfFoxEh_e- RRRKQRPAGK PPYSYVALIT MAIVNSPERK TTLAGIYKFI MDHFPYYR-- ---EADKKWQ NSIRHNLTLN DCFVKLARH-
BfFoxEi_e- RRRKQRPAGK PPYSYVALIT MAIVNSPERK TTLAGIYKFI MDHFPYYR-- ---EADRKWQ NSIRHNLTLN DCFVKLARH-
BfFoxF_fge TNVGVRRHEK PPYSYIALIV MAIQSSATKR LTLSEIYQFL QQRFPFFR-- ---GPYQGWK NSVRHNLSLN ECFIKLPK--
BfFoxG_est ------KHEK PPFSYNALIM MAIRQSPEKR LTLNGIYEFI MKNFPYYR-- ---ENKQGWQ NSIRHNLSLN KCFVKVPRHY
BfFoxH-cDN GKRKYQRYPK PPYSYLALVV MAIQNAPEKK LPLKEIHEAL KKMYPFFR-- ---GDYTGWK DSVRHNLSTY KCFYKVPKDP
BfFoxI_fge ----LFKLVR PPYSYSALIA MAIQAAPEKK LTLSGIYQYV ADNFPFYK-- ---KSKAGWQ NSIRHNLSLN DCFKKVPRDE
BfFoxJ1_es IDYKTNPYVK PPYSYATLIC MAMKETKKSK ITLSDIYKWI KTNFKYYE-- ---MAEPSWQ NSIRHNLSLN KCFTKVPRSK
BfFoxJ23 f DGGAGGRDGK PPYSYANLIT FAINSSPKKK MTLSEIYQWI CDNFPYYR-- ---DAGNGWK NSIRHNLSLN KCFLKVPRSK
BfFoxK-cDN ----QQDNSK PPYSYAQLIV QAITSANDKQ LTLSGIYAHI TKNYPYYR-- ---TADKGWQ NSIRHNLSLN RYFIKVPRSQ
BfFoxL1_fg DVERPERHQK PPYSYIALIA MAIRSSPDQK ITLNGIYQWI MDRFPYYH-- ---DNKQGWQ NSIRHNLSLN DCFVK-----
BfFoxL2_fg EKTSSDPHQK PPYSYVALIA MAIKESQEKR LTLSQIYNYI IQKFPYYE-- ---KNKKGWQ NSIRHNLSLN ECFIKVPR--
BfFoxM-cDN RKSHD--SNR PPYSYMALIQ FAINSSPARR MTLKEIYTWI EGRFPYFK-- ---TAKQGWK NSIRHNLSLH DIFIRETTKC
BfFoxN14b_ NTETEKVYPK PAYSYSCLIA MALKNSKTGC LPVSEIYNFM CDNFPYFK-- ---TAPDGWK NSVRHNLSLN KCFEKVEK-S
BfFoxN14a- ED--DEVFSK PPYSYSCLIA LAMMKSRTGN MPVTEIYSFI REHYPYFK-- ---TAPDGWK NSVRHNLSLN KCFLKIEPSQ
BfFoxN23-c YDAHQHRNSK PPYSFSCLIF MAIEDSPSKR LPVKEIYNWI LEHFPYFV-- ---NAPTGWK NSVRHNLSLN KCFKKVEKEK
BfFoxO-cDN PKKSSRRNAW GNLSYADLIT KAIQSSPEGR LTLSQIYDWM VRCVPYFRDK GDSNSSAGWK NSIRHNLSLH SRFIRVQN--
BfFoxP_gw. ------R PPFTYASLIR QAIIESPEKQ LTLNEIYNWF TRTFAYFR-- ---RNAATWK NAVRHNLSLH KCFVRVE---
BfFoxQ1_es KP-TYHRRPK PPFSYIALIA MAIRDSPNNR LTLAEINDYL MKKFEFFR-- ---GPYTGWR NSVRHNLSLN ECFTKVLRDP
BfFoxQ2a ----PSELEK PRHSYIALIA MAIMSSKDKR LLLGDIYQWI MDNFPFYR-- ---NNERSWR NSIRHNLSLN DCFIKAGR--
BfFoxQ2b ------K PPLSYIALIA KAILGSPAKR LSLGSIYQYI TDNYPYYQ-- ---NRGQGWR NSVRHNLSLN DCFIKAGR--
BfFox1_fge KKKPYRRHAK PPVSYTAMIA AVIQESPEKK LTLLQIVDEL KKRYSFFN-- ---GDYKGWK NSVRHNLSLN KCFVKVKRQA
BfFoxQ2c-c FGPIPHEEPK PSHSYIGLIA MAIMSSKEKK LVLSDIYKYI LDNYPYFR-- ---NRGPGWR NSIRHNLSLN DCFVKMGR--
MmFoxA1-AA TFKRSYPHAK PPYSYISLIT MAIQQAPSKM LTLSEIYQWI MDLFPYYR-- ---QNQQRWQ NSIRHSLSFN DCFVKVARS-
MmFoxA2-AA TYRRSYTHAK PPYSYISLIT MAIQQSPNKM LTLSEIYQWI MDLFPFYR-- ---QNQQRWQ NSIRHSLSFN DCFLKVPRS-
MmFoxA3-NP GYRRPLAHAK PPYSYISLIT MAIQQAPGKM LTLSEIYQWI MDLFPYYR-- ---ENQQRWQ NSIRHSLSFN DCFVKVARS-
MmFoxB1-NP PGRNTYSDQK PPYSYISLTA MAIQSSPEKM LPLSEIYKFI MDRFPYYR-- ---ENTQRWQ NSLRHNLSFN DCFIKIPRR-
MmFoxB2-ED PGKSSYSDQK PPYSYISLTA MAIQHSAEKM LPLSDIYKFI MERFPYYR-- ---EHTQRWQ NSLRHNLSFN DCFIKIPRR-
MmFoxC1-Q6 QPQ-PKDMVK PPYSYIALIT MAIQNAPDKK ITLNGIYQFI MDRFPFYR-- ---DNKQGWQ NSIRHNLSLN ECFVKVPRD-
MmFoxC2-NP QPAAPKDLVK PPYSYIALIT MAIQNAPEKK ITLNGIYQFI MDRFPFYR-- ---ENKQGWQ NSIRHNLSLN ECFVKVPRD-
MmFoxD1-NP AKN---PLVK PPYSYIALIT MAILQSPKKR LTLSEICEFI SSRFPYYR-- ---EKFPAWQ NSIRHNLSLN DCFVKIPRE-
MmFoxD2-O3 ATRS--PLVK PPYSYIALIT MAILQSPKKR LTLSEICEFI SGRFPYYR-- ---EKFPAWQ NSIRHNLSLN DCFVKIPRE-
MmFoxD3-Q6 PNKPKNSLVK PPYSYIALIT MAILQSPQKK LTLSGICEFI SNRFPYYR-- ---EKFPAWQ NSIRHNLSLN DCFVKIPRE-
MmFoxD4-NP TTADGPQPAK PPYSYIALIT MAILQSPHKR LTLSGICAFI SGRFPYYR-- ---RKFPAWQ NSIRHNLSLN DCFVKIPRE-
MmFoxE1-CA RRKRPLQRGK PPYSYIALIA MAIAHAPERR LTLGGIYKFI TERFPFYR-- ---DNPKKWQ NSIRHNLTLN DCFLKIPRE-
MmFoxE3-Q9 RRRRPLQRGK PPYSYIALIA MALAHAPGRR LTLAAIYRFI TERFAFYR-- ---DSPRKWQ NSIRHNLTLN DCFVKVPRE-
MmFoxF1-NP TNAGVRRPEK PPYSYIALIV MAIQSSPSKR LTLSEIYQFL QARFPFFR-- ---GAYQGWK NSVRHNLSLN ECFIKLPK--
MmFoxF2-NP ATSGLRRPEK PPYSYIALIV MAIQSSPSKR LTLSEIYQFL QARFPFFR-- ---GAYQGWK NSVRHNLSLN ECFIKLPK--
MmFoxG1-AA -----GKYEK PPFSYNALIM MAIRQSPEKR LTLNGIYEFI MKNFPYYR-- ---ENKQGWQ NSIRHNLSLN KCFVKVPRHY
MmFoxH1-O8 --KRYLRHDK PPYTYLAMIA LVIQAAPFRR LKLAQIIRQV QAVFPFFR-- ---DDYEGWK DSIRHNLSSN RCFHKVPKDP
MmFoxI1-CA ----LMKLVR PPYSYSALIA MAIHGAPDQR LTLSQIYQYV ADNFPFYN-- ---KSKAGWQ NSIRHNLSLN DCFKKVPRDE
MmFoxI2-NP ----LLRLVR PPYSYSALIA MAIQSAPLRR LTLSQIYQYV AGNFPFYK-- ---RSKAGWQ NSIRHNLSLN DCFKKVPRDE
MmFoxJ1-NP VDYATNPHVK PPYSYATLIC MAMQASKATK ITLSAIYKWI TDNFCYFR-- ---HADPTWQ NSIRHNLSLN KCFIKVPREK
MmFoxJ2-NP DEAAVHQDGK PRYSYATLIT YAINSSPAKK MTLSEIYRWI CDNFPYYK-- ---NAGIGWK NSIRHNLSLN KCFRKVPRPR
MmFoxJ3-AA EEVQQHKDGK PPYSYASLIT FAINSSPKKK MTLSEIYQWI CDNFPYYR-- ---EAGSGWK NSIRHNLSLN KCFLKVPRSK
MmFoxK2-CA ----PKDDSK PPYSYAQLIV QAITMAPDKQ LTLNGIYTHI TKNYPYYR-- ---TADKGWQ NSIRHNLSLN RYFIKVPRSQ
MmFoxK1-NP ----PKDESK PPYSYAQLIV QAISSAQDRQ LTLSGIYAHI TKHYPYYR-- ---TADKGWQ NSIRHNLSLN RYFIKVPRSQ
MmFoxL1-NP GPGRVEPPQK PPYSYIALIA MAIQDAPEQR VTLNGIYQFI MDRFPFYH-- ---DNRQGWQ NSIRHNLSLN ECFVKVPRE-
MmFoxL2-NP TPEKPDPAQK PPYSYVALIA MAIRESAEKR LTLSGIYQYI IAKFPFYE-- ---KNKKGWQ NSIRHNLSLN ECFIKVPR--
MmFoxM1-O0 TSWQDSVSER PPYSYMAMIQ FAINSTERKR MTLKDIYTWI EDHFPYFKH- ---IAKPGWK NSIRHNLSLH DMFVRETSAN
MmFoxN1-NP AEGHQPLFPK PIYSYSILIF MALKNSKTGS LPVSEIYNFM TEHFPYFK-- ---TAPDGWK NSVRHNLSLN KCFEKVENKS
MmFoxN4-AA QEPHPKHYPK PIYSYSCLIA MALKNSKTGS CPVSEIYSFM KT-LPYFK-- ---TAPDGWK NSVRHNLSLN KCFEKVETKS
MmFoxN2-NP --EKKSATSK PPYSFSLLIY MAIEHSPNKC LPVKEIYSWI LDRFPYFA-- ---TAPTGWK NSVRHNLSLN KCFQKVERSH
MmFoxO1-Q9 KTSSSRRNAW GNLSYADLIT KAIESSAEKR LTLSQIYEWM VKSVPYFKDK GDSNSSAGWK NSIRHNLSLH SKFIRVQN--
MmFoxO3-NP KCSS-RRNAW GNLSYADLIT RAIESSPDKR LTLSQIYEWM VRCVPYFKDK GDSNSSAGWK NSIRHNLSLH SRFMRVQN--
MmFoxO4-NP KGGS-RRNAW GNQSYAELIS QAIESAPEKR LTLAQIYEWM VRTVPYFKDK GDSNSSAGWK NSIRHNLSLH SKFIKVHN--
MmFoxO6-CA KAKSSRRNAW GNLSYADLIT KAIESAPDKR LTLSQIYDWM VRYVPYFKDK GDSNSSAGWK NSIRHNLSLH TRFIRVQN--
MmFoxP1-P5 QEFYKNAEVR PPFTYASLIR QAILESPEKQ LTLNEIYNWF TRMFAYFR-- ---RNAATWK NAVRHNLSLH KCFVRVE---
MmFoxP2-NP YEFYKNADVR PPFTYATLIR QAIMESSDRQ LTLNEIYSWF TRTFAYFR-- ---RNAATWK NAVRHNLSLH KCFVRVE---
MmFoxP4-NP HEFYKNADVR PPFTYASLIR QAILETPDRQ LTLNEIYNWF TRMFAYFR-- ---RNTATWK NAVRHNLSLH KCFVRVE---
MmFoxP3-Q9 MDYFKYHNMR PPFTYATLIR WAILEAPERQ RTLNEIYHWF TRMFAYFR-- ---NHPATWK NAIRHNLSLH KCFVRVE---
MmFoxQ1-CA RSKPYTRRPK PPYSYIALIA MAIRDSAGGR LTLAEINEYL MGKFPFFR-- ---GSYTGWR NSVRHNLSLN DCFVKVLRDP
MmFoxR1-Q3 ---EGRLWSR PPLHYFHLIA LALRNSPPCG LSVQQIYSFT REHFPFFR-- ---TAPEAWK NTVRHNLSFR DSFEKVPASR
MmFoxR2-Q3 ---EKESWPR PPLNYSHLVA LALKSSPSCG LNVQQIYNFT RQHFPYFR-- ---TAPEGWK NTIRHNLCSL TCFEKVPVDL
MmFoxS1-NP APS--AEPTK PPYSYIALIA MAIQSSPGQR ATLSGIYRYI MGRFAFYR-- ---HNRPGWQ NSIRHNLSLN ECFVKVPRD-
DmSpp1-NP4 -----SDTKK PPYSYNALIM MAIQDSPEQR LTLNGIYQYL INRFPYFK-- ---ANKRGWQ NSIRHNLSLN KCFTKIPRSY
DmSpp2-NP4 -----KGNEK PPYSYNALIM MAIRQSSEKR LTLNGIYEYI MTNHPYYR-- ---DNKQGWQ NSIRHNLSLN KCFVKVPRHY
DmFoxF-AAK KKSGTRRPEK PALSYINMIG HAIKESPTGK LTLSEIYAYL QKSYEFFR-- ---GPYVGWK NSVRHNLSLN ECFKKLPKGM
Dm59A-NP52 SGSSGGPLVK PPYSYIALIT MAILQSPHKK LTLSGICDFI MSRFPYYK-- ---DKFPAWQ NSIRHNLSLN DCFIKVPRE-
DmFoxN14-N LPPVGSPFPK PAYSYSCLIA LALKNSRAGS LPVSEIYSFL CQHFPYFE-- ---NAPSGWK NSVRHNLSLN KCFEKIERPA
DmFoxA-NP5 TYRRSYTHAK PPYSYISLIT MAIQNNPTRM LTLSEIYQFI MDLFPFYR-- ---QNQQRWQ NSIRHSLSFN DCFVKIPRT-
Dm64A-NP52 FLHNSHRPEK PPFSYIALIA MAISSAPNQR LTLSGIYKFI MDKFPYYR-- ---ENKQGWQ NSIRHNLSLN DCFVKIPRDK
DmFoxC-NP5 APHQNKEIVK PPYSYIALIA MAIQNAADKK VTLNGIYQYI MERFPYYR-- ---DNKQGWQ NSIRHNLSLN ECFVKVARD-
Dm96Ca-NP5 PSRESYGEQK PPYSYISLTA MAIWSSPEKM LPLSDIYKFI TDRFPYYR-- ---KNTQRWQ NSLRHNLSFN DCFIKVPRR-
Dm96Cb-NP5 PLKMSYGDQK PPYSYISLTA MAIIHSPQRL LPLSEIYRFI MDQFPFYR-- ---KNTQKWQ NSLRHNLSFN DCFIKVPRN-
DmCG32006- SKYETDVTEK PPFNYSHIIG MAMLQN--GR ITLQQLCSWI EAKFAFFR------VRKKWN NSIRHNLSLH HCFRNRKREE
DmCG11152- R-IFQPEEPK PQHSYIGLIA MAILSSTDMK LVLSDIYQYI LDNYPYFR-- ---SRGPGWR NSIRHNLSLN DCFIKSGR--
DmCG9571-N ------NAK PAFTYSALIV MAIWSSSEKR LTLSGICKWI ADNFPYYR-- ---TRKSVWQ NSIRHNLSLN PFFVRVPRAL
DmCG16899- ------LKEQVLMCN RAIIDSPDKQ LTLNEIYNWF QNTFCYFR-- ---RNAATWK NAVRHNLSLH KCFMRVE---
DmMnf-NP72 STASYNHNEK PPYSYAQLIV QAISAAPDKQ LTLSGIYSFI VKHYPYYRK- ---ETNKGWQ NSIRHNLSLN RYFIKVARSQ
Dm3F-NP570 ------FTYTELIE YALEDKGE-- LTVSGIYQWI SDRFPYYK-- ---SNDDRWK NSVRHNLSIN PHFRKGVK--
DmFoxO-NP9 KKNSSRRNAW GNLSYADLIT HAIGSATDKR LTLSQIYEWM VQNVPYFKDK GDSNSSAGWK NSIRHNLSLH NRFMRVQN--
DmFoxN23-N YDPLVHTNNK PPYSFSSLIF MAIEGSNEKA LPVKEIYAWI VQHFPYFK-- ---TAPNGWK NSVRHNLSLN KSFVKVEKAP
SpFoxAB-AB ------VK PPYSYIALIT MALEGSKDGM MTLNEVYQFI MDKFPYFR-- ---ENQQRWQ NSIRHNLSLN DCFIKVPRAP
DrFoxQ2-AA HVKSEGTDEK PAQSYIALIS MAILDSDEKK LLLCDIYQWI MDHYPYFK-- ---SKDKNWR NSVRHNLSLN ECFIKAGR--
SpFoxY NGKKPSRVDL PGFTYAELIT MAIQSSPSRM MTIVDIQQFF RDRFPCFR-- ---TSYKGWH NSIRHNLSAR ECFYKVPIV-
....|....| ....|....| ....|....| ....|....| ....|....| ....|....| ....|....| ....|....|
90 100 110 120 130 140 150 160
BfFoxAa_fg ------PDRPG KGSYWTLHPE AGNMFE----
BfFoxAb_es ------PDRPG KGSYWTLHPN AHSMFE----
BfFoxB CAD ------PDQPG QGSFWALHPM CGDMFE----
BfFoxAB-cD ------CEQPG KGGLWALHPD CGNMFA----
BfFoxC-CAH ------DKKPG KGSYWSLDPD SYNMFD----
BfFoxD_est ------PGNPG KGNYWTLDPA SEDMFD----
BfFoxEa_es ------PGRPG KGNYWTLDPA AEDMFD----
BfFoxEb_es ------PNRPG KGSLWALDPG AEGMFD----
BfFoxEc_es ------PNRPG KGSLWALDPG AEGMFD----
BfFoxEd_e- ------PNRPG KGSLWALDPG AEGMFD----
BfFoxEe_e- ------PNRPG KGSLWALDPG AEGMFD----
BfFoxEf_e- ------PNRPG KGSLWALDPG AEGMFD----
BfFoxEg_e- ------PNRPG KGSLWALDPG AEGMFD----
BfFoxEh_e- ------PNRPG KGSLWALDPG AEGMFD----
BfFoxEi_e- ------PNRPG KGSLWALDPG AEGMFD----
BfFoxF_fge ------GLGRPG KGHYWTIDPA SEFMFE----
BfFoxG_est ------DDPG KGNYWMLDPS SDDVFI----
BfFoxH-cDN ------SRPFA KGNYWAVYED KVPKDA----
BfFoxI_fge ------DDPG KGNYWTLDPN CEKMFD----
BfFoxJ1_es ------NEPG KGGFWKIDPQ HADMIV----
BfFoxJ23 f ------DDPG KGSYWAIDNN PQEDPIP---
BfFoxK-cDN ------EEPG KGSFWRIDPS CEAKLT----
BfFoxL1_fg ------D CEEMFE----
BfFoxL2_fg ------EGGGER KGNYWTLDPA CEDMFE----
BfFoxM-cDN ESG------R ALSYWTLCHE AKERCLTIDQ
BfFoxN14b_ TGG------TSK KGCLWTLNPA KVAKME----
BfFoxN14a- ADP------NR KGCLWALHPD KVDKMM----
BfFoxN23-c GQ------SIG KGSLWMIDP- AYRPNL----
BfFoxO-cDN ------EGTG KSSWWMLNPD -AKGGKS---
BfFoxP_gw. ------NV KGAVWTVDEI EFQKRR----
BfFoxQ1_es ------SRPWG KDNYWTINPN SEYTFA----
BfFoxQ2a ------SQDG KGNYWAIHPA NMEDFS----
BfFoxQ2b ------CEDG KGNYWAIHPA NIEDFA----
BfFox1_fge PHKTGQYDER CGISQGSRLG LPAVRDATPF LGTTPKQART DPLATGPSYG VPRDADRPFG KDNFWTVDGI ESYLNP----
BfFoxQ2c-c ------SANG KGHFWAVHPA NVDDFA----
MmFoxA1-AA ------PDKPG KGSYWTLHPD SGNMFE----
MmFoxA2-AA ------PDKPG KGSFWTLHPD SGNMFE----
MmFoxA3-NP ------PDKPG KGSYWALHPS SGNMFE----
MmFoxB1-NP ------PDQPG KGSFWALHPS CGDMFE----
MmFoxB2-ED ------PDQPG KGSFWALHPD CGDMFE----
MmFoxC1-Q6 ------DKKPG KGSYWTLDPD SYNMFE----
MmFoxC2-NP ------DKKPG KGSYWTLDPD SYNMFE----
MmFoxD1-NP ------PGNPG KGNYWTLDPE SADMFD----
MmFoxD2-O3 ------PGNPG KGNYWTLDPE SADMFD----
MmFoxD3-Q6 ------PGNPG KGNYWTLDPQ SEDMFD----
MmFoxD4-NP ------PGHPG KGNYWSLDPA SQDMFD----
MmFoxE1-CA ------AGRPG KGNYWALDPN AEDMFE----
MmFoxE3-Q9 ------PGNPG KGNYWTLDPA AADMFD----
MmFoxF1-NP ------GLGRPG KGHYWTIDPA SEFMFE----
MmFoxF2-NP ------GLGRPG KGHYWTIDPA SEFMFE----
MmFoxG1-AA ------DDPG KGNYWMLDPS SDDVFI----
MmFoxH1-O8 ------AKPQA KGNFWAVDVS LIPAEA----
MmFoxI1-CA ------DDPG KGNYWTLDPN CEKMFD----
MmFoxI2-NP ------NDPG KGNYWTLDPN CEKMFD----
MmFoxJ1-NP ------DEPG KGGFWRIDPQ YAERLL----
MmFoxJ2-NP ------DDPG KGSYWTIDTC PDISRKR---
MmFoxJ3-AA ------DDPG KGSYWAIDTN PKEDTLP---
MmFoxK2-CA ------EEPG KGSFWRIDPA SESKLV----
MmFoxK1-NP ------EEPG KGSFWRIDPA SEAKLV----
MmFoxL1-NP ------KGRPG KGSYWTLDPR CLDMFE----
MmFoxL2-NP ------EGGGER KGNYWTLDPA CEDMFE----
MmFoxM1-O0 G------KVSFWTIHPS ANR-HLTLDQ
MmFoxN1-NP GSS------SR KGCLWALNPS KIDKMQ----
MmFoxN4-AA SGS------SR KGCLWALNLA RIDKME----
MmFoxN2-NP GK------VNG KGSLWCVDP- EYKPNL----
MmFoxO1-Q9 ------EGTG KSSWWMLNPE GGKSGKS---
MmFoxO3-NP ------EGTG KSSWWIINPD GGKSGKA---
MmFoxO4-NP ------EATG KSSWWMLNPD GGKGGKA---
MmFoxO6-CA ------EGTG KSSWWMLNPE GGKTGKT---
MmFoxP1-P5 ------NV KGAVWTVDEV EFQKRR----
MmFoxP2-NP ------NV KGAVWTVDEV EYQKRR----
MmFoxP4-NP ------NV KGAVWTVDER EYQKRR----
MmFoxP3-Q9 ------SE KGAVWTVDEF EFRKKR----
MmFoxQ1-CA ------SRPWG KDNYWMLNPN SEYTFA----
MmFoxR1-Q3 QGG------ASTGP RSCLWKLTEE GHRRFS----
MmFoxR2-Q3 EDE------PDGKP RSFLWKLTDE GNRFFQ----
MmFoxS1-NP ------DRKPG KGSYWTLDPD CHDMFQ----
DmSpp1-NP4 ------DDPG KGNYWILDPS AEEVFI----
DmSpp2-NP4 ------DDPG KGNYWMLDPS AEDVFI----
DmFoxF-AAK ------GVGKPG KGNYWTIDEN SAHLFED---
Dm59A-NP52 ------PGNPG KGNFWTLDPL AEDMFD----
DmFoxN14-N TNG------NQR-- KGCRWAMNPD RINKMD----
DmFoxA-NP5 ------PDKPG KGSFWTLHPD SGNMFE----
Dm64A-NP52 NTIED------NDSAG KGSYWMLDSS ASDMFE----
DmFoxC-NP5 ------DKKPG KGSYWTLDPD SYNMFD----
Dm96Ca-NP5 ------PDRPG KGAYWALHPQ AFDMFE----
Dm96Cb-NP5 ------VTKAG KGSYWTLHPM AFDMFE----
DmCG32006- RG------KGGYWELGVD PKK------
DmCG11152- ------SANG KGHYWAIHPA NMEDFR----
DmCG9571-N ------DDPG RGHYWALDPY AEDLSI----
DmCG16899- ------NV KGAVWTVDEI EFYKRR----
DmMnf-NP72 ------DEPG KGSFWRIDPD SGAKLI----
Dm3F-NP570 ------APQG AGHLWAISSG DSAENVL---
DmFoxO-NP9 ------EGTG KSSWWMLNPE -AKPGKS---
DmFoxN23-N N------MG KGSLWRVEP- QQRQNL----
SpFoxAB-AB ------GRPG KGNYWALHP------
DrFoxQ2-AA ------SDNG KGHFWAIHPA NFQDFS----
SpFoxY ------DKRHKC RTHYWMINPS CSHCRD----
....|....| ....|....| ....|....| ....|....| ....|....| ....|.
170 180 190 200 210
BfFoxAa_fg ------NGCYLR RQKRFKCEKK LAMKMA
BfFoxAb_es ------NGCYLR RQKRFKCERK AALKAE
BfFoxB CAD ------NGSFLR RRKRFKSMPR QQ----
BfFoxAB-cD ------KGSYLR RTARFRSSKT EESQDG
BfFoxC-CAH ------NGSYLR RRRRFKKADA VKERED
BfFoxD_est ------NGSFLR RRKRFKRQAP DVLR--
BfFoxEa_es ------NGSFLR RRKRFKRADS STYM--
BfFoxEb_es ------NGSYLR RRSRYKRSHQ TNNN--
BfFoxEc_es ------NGSYLR RRSRYRRSHQ TNNN--
BfFoxEd_e- ------NGSYLR RRSRLE------
BfFoxEe_e- ------NGSYLR RRSRLETFV------
BfFoxEf_e- ------NGSYLR RRSRLEKFV------
BfFoxEg_e- ------NGSYLR RRSRLETFV------
BfFoxEh_e- ------NGSYLR RRSRLETFV------
BfFoxEi_e- ------NGSYLR RRSR------
BfFoxF_fge ------EGSFRR RPRGFRRKCQ ALKPY-
BfFoxG_est ------GGTTGK LRRRSTAAAR SRLAFR
BfFoxH-cDN ------LKKQDS SSEREGEADY ETPGSV
BfFoxI_fge ------NGNFRR KRKRRDQSGG AGGQQN
BfFoxJ1_es ------NGTLKK RRPSSTLESY PPAKKI
BfFoxJ23 f ------ARQKPR KR--RSSDRP YSPEE-
BfFoxK-cDN ------EQAWRR RRQRGVPCFR TPFGGG
BfFoxL1_fg ------NGNYRR RKRKPKTPYK PAEGPD
BfFoxL2_fg ------KGNYRR R----RRMKR PYRPP-
BfFoxM-cDN MER------REARLR CTTNTQIYPS GPPPLLPCPP KPSAYT
BfFoxN14b_ ------EEVQKI TRKDPQAIRR CMANPE
BfFoxN14a- ------SEIRKW KKKDPEAIRR SMAYPV
BfFoxN23-c ------LQALKK TPIHPYHHIF TTPPPS
BfFoxO-cDN ------PRRRAS SMDTNNSKYE KKRGRA
BfFoxP_gw. ------QQK------
BfFoxQ1_es ------DGVFRR RRKRINRKSS RKAAAA
BfFoxQ2a ------RGDFHR RRARRNVRRY TAMAQH
BfFoxQ2b ------RGDFRQ R---RRSRRR RGAKKD
BfFox1_fge ------DGTFRQ RRKRAQPGTA TTRKAV
BfFoxQ2c-c ------QGDFRR RRAQRKVRKH MGLLPE
MmFoxA1-AA ------NGCYLR RQKRFKCEKQ PGAGGG
MmFoxA2-AA ------NGCYLR RQKRFKCEKQ LALKEA
MmFoxA3-NP ------NGCYLR RQKRFKLEEK -AKKGN
MmFoxB1-NP ------NGSFLR RRKRFKVLKS D-----
MmFoxB2-ED ------NGSFLR RRKRFKVLRA DHAHLH
MmFoxC1-Q6 ------NGSFLR RRRRFKKKDA VKDKEE
MmFoxC2-NP ------NGSFLR RRRRFKKKDV PKDKEE
MmFoxD1-NP ------NGSFLR RRKRFKRQPL LAPH--
MmFoxD2-O3 ------NGSFLR RRKRFKRQPL PPPHPH
MmFoxD3-Q6 ------NGSFLR RRKRFKRHQQ EHLR--
MmFoxD4-NP ------NGSFLR RRKRFKRHHP PSGG--
MmFoxE1-CA ------SGSFLR RRKRFKRSDL STYPAY
MmFoxE3-Q9 ------NGSFLR RRKRFKRAEL P-----
MmFoxF1-NP ------EGSFRR RPRGFRRKCQ ALKP--
MmFoxF2-NP ------EGSFRR RPRGFRRKCQ ALKP--
MmFoxG1-AA ------GGTTGK LRRRSTTS-R AKLAFK
MmFoxH1-O8 ------LRLQNT ALCRR----W QNRGTH
MmFoxI1-CA ------NGNFRR KRKRKSDSSS STSSLA
MmFoxI2-NP ------NGNFRR KRRRRGETSE AAVPGA
MmFoxJ1-NP ------SGAFKK RRLPPVHIHP AFARQA
MmFoxJ2-NP ------RHPPDD DLSQDSPEQE ASKSP-
MmFoxJ3-AA ------TRPKKR ARSVERASTP YSIDSD
MmFoxK2-CA ------EQAFRK RRPRGVPCFR TPLG-P
MmFoxK1-NP ------EQAFRK RRQRGVSCFR TPFG-P
MmFoxL1-NP ------NGNYRR RKRKPKP------
MmFoxL2-NP ------KGNYRR R----RRMKR PFRPP-
MmFoxM1-O0 VFKPLEPGSP QSPEHLESQQ KRPNPELHRN VTIKTEIPLG ARRKMKPLLP RVSSY-
MmFoxN1-NP ------EELQKW KRKDPIAVRK SMAKPE
MmFoxN4-AA ------EEMHKW KRKDLASIHR SMANPE
MmFoxN2-NP ------MQALKK QPFS------S
MmFoxO1-Q9 ------PRRRAA SMD-NNSKFA KSRGRA
MmFoxO3-NP ------PRRRAV SMD-NSNKYT KSRGRA
MmFoxO4-NP ------PRRRAA SMD-SSSKLL RGRSKG
MmFoxO6-CA ------PRRRAV SMD-NGAKFL RIKGKA
MmFoxP1-P5 ------PQKISG NPSLIKNMQS SHAYCT
MmFoxP2-NP ------SQKITG SPTLVKNIPT SLGYGA
MmFoxP4-NP ------PPKMTG SPTLVKNMIS GLSYG-
MmFoxP3-Q9 ------SQRPNK CSNPCP------
MmFoxQ1-CA ------DGVFRR RRKRLSHRTT VSASGL
MmFoxR1-Q3 ------KEARTL ASTQLQSIQQ CMSQPG
MmFoxR2-Q3 ------EDTRVL AYARRESIKQ SMRQPE
MmFoxS1-NP ------HGSFLR RRRRFTKRTG AQGTKG
DmSpp1-NP4 ------GETTGK LRR------
DmSpp2-NP4 ------GGSTGK LRRRTTAASR SRLAAF
DmFoxF-AAK ------EGSLRR RPRGYRSKIK VKPYAG
Dm59A-NP52 ------NGSFLR RRKRYKRAPT MQRF--
DmFoxN14-N ------EEVQKW SRKDPAAIRG AMVYPQ
DmFoxA-NP5 ------NGCYLR RQKRFKDEKK EAIRQL
Dm64A-NP52 ------QGNYRR RRTRRQRHCG HPNRYE
DmFoxC-NP5 ------NGSFLR RRRRFKKKDV MREKEE
Dm96Ca-NP5 ------NGSLLR RRKRFKLHKN DK----
Dm96Cb-NP5 ------NGSLLR RRKRFRVKQL EK----
DmCG32006- ------CDRKRIR NRKIFHPTQN QTAKLQ
DmCG11152- ------KGDFRR RKAQRKVRKH MGLSVD
DmCG9571-N ------GETTGR LRR------
DmCG16899- ------PQRTAG ----IGNNLT GATNSP
DmMnf-NP72 ------DHSYKK RRQRSSQGFR PPYG--
Dm3F-NP570 ------AWEHKK QRL---DLFF KMESIN
DmFoxO-NP9 ------VRRRAA SME--TSRYE KRRGRA
DmFoxN23-N ------IQALNR SPFFPNSAVD KISPSL
SpFoxAB-AB ------
DrFoxQ2-AA ------NGDYHR RRARRRIRRV TGQLPY
SpFoxY ------GNG LLQEARQWRT RRMMAKNVIR KKRRGSKKNG SSTTT.
2. Alignment used for FoxF/Q/H molecular phylogenetic analysis
....|....| ....|....| ....|....| ....|....| ....|....| ....|....| ....|....| ....|....| ....|....|
10 20 30 40 50 60 70 80 90
MmFoxH2-AA KRYLRHDKPP YTYLAMIALV IQAAPFRRLK LAQIIRQVQA VFPFFRDD-Y EGWKDSIRHN LSSNRCFHKV PKDP------
HsFoxH1-O7 KRYLRHDKPP YTYLAMIALV IQAAPSRRLK LAQIIRQVQA VFPFFRED-Y EGWKDSIRHN LSSNRCFRKV PKDP------
MmFoxH1-O8 KRYLRHDKPP YTYLAMIALV IQAAPFRRLK LAQIIRQVQA VFPFFRDD-Y EGWKDSIRHN LSSNRCFHKV PKDP------
XlFAST3-CA KNYQRYAKPP YSYLAMISLV IQNSPEKRLK LSQILQDISS LFPFFKGN-Y QGWKDSIRHN LSSNDCFRKV LKDP------
DrFoxH1-AA KNYQRYPKPP YSYLAMIAMV IQNSPEKKLT LSEILKEIST LFPFFKGN-Y KGWRDSVRHN LSSYDCFVKV LKDP------
CiFoxHa-BA KKYRRYEKPP YSYVGLIALA IQNSTTKMLK LSDILLRIST MFPFFKGE-Y QGWRDSVRHN LSQNKCFKKV LPDP------
CiFoxHb-BA KRYKRYAKPP YSYVSLITLS ILSSPEKKLR LSQILKRISE MFPFFNGS-Y QGWRDSVRHN LSQNECFVKV LKNP------
XtFoxH1-CA KNYHRYAKPP YSYLAMIALV IQNSPEKRLK LSQILKEVST LFPFFKGD-Y MGWKDSIRHN LSSNDCFKKV LKDP------
BfFoxH RKYQRYPKPP YSYLALVVMA IQNAPEKKLP LKEIHEALKK MYPFFRGD-Y TGWKDSVRHN LSTYKCFYKV PKDP------
BfFoxQ2a ------KPR HSYIALIAMA IMSSKDKRLL LGDIYQWIMD NFPFYRNN-E RSWRNSIRHN LSLNDCFIKA GRS------
BfFoxQ2c -MPHEEPKPS HSYIGLIAMA IMSSKEKKLV LSDIYKYILD NYPYFRNR-G PGWRNSIRHN LSLNDCFVKM GRS------
BfFoxQ2b ------KPP LSYIALIAKA ILGSPAKRLS LGSIYQYITD NYPYYQNR-G QGWRNSVRHN LSLNDCFIKA GRC------
BfFox1 KPYRRHAKPP VSYTAMIAAV IQESPEKKLT LLQIVDELKK RYSFFNGD-Y KGWKNSVRHN LSLNKCFVKV KRQAPHKTGQ YDERCGISQG
BfFoxQ1 PTYHRRPKPP FSYIALIAMA IRDSPNNRLT LAEINDYLMK KFEFFRGP-Y TGWRNSVRHN LSLNECFTKV LRDP------
BfFoxF VGVRRHEKPP YSYIALIVMA IQSSATKRLT LSEIYQFLQQ RFPFFRGP-Y QGWKNSVRHN LSLNECFIKL PKGL------
DmCG11152- IFQPEEPKPQ HSYIGLIAMA ILSSTDMKLV LSDIYQYILD NYPYFRSR-G PGWRNSIRHN LSLNDCFIKS GRS------
SpFoxQ2-AB ---PSTKKPP HSYIALIAMA IINSQDKHLL LCDIYEYIMK RFPFFKDN-E RSWRNSIRHN LSLNECFIKA GRS------
TcFoxQ2-XP ALQPEEPKPQ HSYIGLIAMA ILSSPEGKLV LSDIYQHILD HYPYFRTR-G PGWRNSIRHN LSLNDCFIKA GRS------
ChFoxQ2a-A QGKKEDVKPT QSYIALIATA ILKSKDKRLV LSDIYKYILD NYSYFQSQ-D KSWRNSIRHN LSLNECFIKV GRS------
ChFoxQ2b-A DEGTTDGKPN HSYISLIANA ILSSKEKRLV LSDIYQFVLD TQPYFRNKAG QGWRNSIRHN LSLNECFVKA GRS------
OaFoxQ2-XP -GQASLRKPG QSYVALISTA ILASPKRKLL LSDIYQWIMD TYPYFKNQ-E KSWRNSIRHN LSLNECFVKA GRS------
DrFoxQ2-AA KSEGTDEKPA QSYIALISMA ILDSDEKKLL LCDIYQWIMD HYPYFKSK-D KNWRNSVRHN LSLNECFIKA GRS------
CeFoxQ2-CA PTECQQPKPQ HSYIGLIAMA ILSSPQKKMV LAEVYEWIMN EYPYFRSR-G AGWRNSIRHN LSLNDCFVKA GRA------
SpFoxF-XP7 AGIRRHEKPP YSYIALIVMA IQSSPAKRLT LSEIYQFLMQ RFPFFRGP-Y QGWKNSVRHN LSLNECFIKL PKGL------
XlFoxF2-NP SGLRRPEKPP YSYIALIVMA IQSSPTKRLT LSEIYQFLQA RFPFFRGS-Y QGWKNSVRHN LSLNECFIKL PKGL------
XlFoxF1-Q9 AGIRRPEKPP YSYIALIVMA IQSSPTKRLT LSEIYQFLQS RFPFFRGS-Y QGWKNSVRHN LSLNECFIKL PKGL------
SpFoxQ1-AB PTYHRHPKPP FSYIALIAMA IRDSGHGKLT LAEINEYLMK KFPFFRGS-Y TGWRNSVRHN LSLNECFRKI LRDP------
XtFoxQ1-AB KTYTRRPKPP YSYIALIAMA IKDSASGRLT LAEINDYLMK KFPFFRGS-Y TGWRNSVRHN LSLNDCFVKV LRDP------
MmFoxF1-NP AGVRRPEKPP YSYIALIVMA IQSSPSKRLT LSEIYQFLQA RFPFFRGA-Y QGWKNSVRHN LSLNECFIKL PKGL------
MmFoxF2-NP SGLRRPEKPP YSYIALIVMA IQSSPSKRLT LSEIYQFLQA RFPFFRGA-Y QGWKNSVRHN LSLNECFIKL PKGL------
MmFoxQ1-CA -PYTRRPKPP YSYIALIAMA IRDSAGGRLT LAEINEYLMG KFPFFRGS-Y TGWRNSVRHN LSLNDCFVKV LRDP------
MmFoxA1-AA KRSYPHAKPP YSYISLITMA IQQAPSKMLT LSEIYQWIMD LFPYYRQN-Q QRWQNSIRHS LSFNDCFVKV ARSP------
MmFoxB1-NP ------KPP YSYISLTAMA IQSSPEKMLP LSEIYKFIMD RFPYYREN-T QRWQNSLRHN LSFNDCFIKI PRRP------
MmFoxC1-Q6 -QPKDMVKPP YSYIALITMA IQNAPDKKIT LNGIYQFIMD RFPFYRDN-K QGWQNSIRHN LSLNECFVKV PRDD------
....|....| ....|....| ....|....| ....|....| ....|....| ....|....| ....|....| ....|....| ....|....|
100 110 120 130 140 150 160 170 180
MmFoxH2-AA ------A KPQAKGNFWA VDVSLIPAEA LRLQNTALCR RWQNRGTHRA FAKDLSPYVL
HsFoxH1-O7 ------A KPQAKGNFWA VDVSLIPAEA LRLQNTALCR RWQNGGARGA FAKDLGPYVL
MmFoxH1-O8 ------A KPQAKGNFWA VDVSLIPAEA LRLQNTALCR RWQNRGTHRA FAKDLSPYVL
XlFAST3-CA ------L KPQAKGNYWT VDVTRIPPDA LKLQNTAVTR ------QDL FPLDLAPYIL
DrFoxH1-AA ------G KPQGKGNFWT VEVNRIPLEL LKRQNTAVSR QD-----ETI FAQDLAPYIF
CiFoxHa-BA ------S RPHSKGNYWT VDIASIPPEK LKRQN------TS VSRNVAP-GF
CiFoxHb-BA ------Y RPTAKGNYWT VNITAIPHEL LLRQN------TL VSRYAQDSGF
XtFoxH1-CA ------G KPQAKGNFWT VDVSRIPLDA MKLQNTALTR GG-----SDY FVQDLAPYIL
BfFoxH ------S RPFAKGNYWA VYEDKVPKDA LKKQDSSSER EG-----EAD YETPGSVCTT
BfFoxQ2a ------QDGKGNYWA IHPANMEDFS RG------D FHRRRARRNV
BfFoxQ2c ------ANGKGHFWA VHPANVDDFA QG------D FRRRR-----
BfFoxQ2b ------EDGKGNYWA IHPANIEDFA RG------D FRQRRRSRRR
BfFox1 SRLGLPAVRD ATPFLGTTPK QARTDPLATG PSYGVPRDAD RPFGKDNFWT VDGIESYLNP DG------T FRQRRKRAQP
BfFoxQ1 ------S RPWGKDNYWT INPNSEYTFA DG------V FRRRRKRINR
BfFoxF ------GRPGKGHYWT IDPASEFMFE EG------S FAGDAR-VRR
DmCG11152- ------ANGKGHYWA IHPANMEDFR KG------D FRRRKAQRKV
SpFoxQ2-AB ------GDGRGHFWA IHPANLEDFA RG------D YRRRQARRRA
TcFoxQ2-XP ------ANGKGHYWA IHPANVDDFR KG------D FRRRKAQRKV
ChFoxQ2a-A ------EQGKGHYWA IHPANYDDFS QG------D FRRRRARRRV
ChFoxQ2b-A ------PNGKGHFWA INPANFDDFS KG------D FRRRRAQRRA
OaFoxQ2-XP ------DSGKGHFWT IHPANLEDFA KG------E YHRQRARSQL
DrFoxQ2-AA ------DNGKGHFWA IHPANFQDFS NG------D YHRRRARRRI
CeFoxQ2-CA ------ANGKGHYWA VHPACVKDFE RG------D FRRRRAQRKV
SpFoxF-XP7 ------GRPGKGHYWT IDPASEFMFE EG------S FRRRPRGFRR
XlFoxF2-NP ------GRPGKGHYWT IDPASEFMFE EG------S FRRRPRGFRR
XlFoxF1-Q9 ------GRPGKGHYWT IDPASEFMFE EG------S FRRRPRGFRR
SpFoxQ1-AB ------S RPWGKDNYWT INESSEYTFA DG------V FRRRRKRISK
XtFoxQ1-AB ------S RPWGKDNYWM LNPNSEYTFA DG------V FRRRRKRLNR
MmFoxF1-NP ------GRPGKGHYWT IDPASEFMFE EG------S FRRRPRGFRR
MmFoxF2-NP ------GRPGKGHYWT IDPASEFMFE EG------S FRRRPRGFRR
MmFoxQ1-CA ------S RPWGKDNYWM LNPNSEYTFA DG------V FRRRRKRLSH
MmFoxA1-AA ------DKPGKGSYWT LHPDSGNMFE NG------C YLRRQKRFKC
MmFoxB1-NP ------DQPGKGSFWA LHPSCGDMFE NG------S FLRRRKRFKV
MmFoxC1-Q6 ------KKPGKGSYWT LDPDSYNMFE NG------S FLRRRRRFKK
..
MmFoxH2-AA HG
HsFoxH1-O7 HG
MmFoxH1-O8 HG
XlFAST3-CA HG
DrFoxH1-AA QG
CiFoxHa-BA TY
CiFoxHb-BA RY
XtFoxH1-CA HN
BfFoxH TS
BfFoxQ2a RR
BfFoxQ2c --
BfFoxQ2b RG
BfFox1 GT
BfFoxQ1 KS
BfFoxF KC
DmCG11152- RK
SpFoxQ2-AB RS
TcFoxQ2-XP RK
ChFoxQ2a-A RR
ChFoxQ2b-A RR
OaFoxQ2-XP RR
DrFoxQ2-AA RR
CeFoxQ2-CA RR
SpFoxF-XP7 KC
XlFoxF2-NP KC
XlFoxF1-Q9 KC
SpFoxQ1-AB RA
XtFoxQ1-AB VT
MmFoxF1-NP KC
MmFoxF2-NP KC
MmFoxQ1-CA RT
MmFoxA1-AA EK
MmFoxB1-NP LK
MmFoxC1-Q6 KD
3. Alignment used for FoxD/E molecular phylogenetic analysis
....|....| ....|....| ....|....| ....|....| ....|....| ....|....| ....|....| ....|....|
10 20 30 40 50 60 70 80
BfFoxAa_fg EKAYRRSYTH AKPPYSYISL ITMSIQSSPN KMVTLAEIYQ FIMDLFPYYR QNQQRWQNSI RHSLSFNDCF VKVPRTPDRP
BfFoxB CAD PRPGKDSYGN EKPPYSYISL TAMAIQSSGE KMLPLSDIYK FIMDRFPFYR QNTQRWQNSL RHNL-FNDCF IKIPRRPDQP
BfFoxC-CAH SHH-HTSKDM VKPPYSYIAL IAMAIQNAPD KKVTLNGIYQ FIMDRFPYYR ENKQGWQNSI RHNLSLNECF IKVPRDDKKP
BfFoxD_est NQSVRKKSNL VKPPYSYIAL ITMSILQSPQ KKLTLSQICE FIMNRFPYYR ERFPVWQNSI RHNLSLNDCF VKIPREPGNP
BfFoxEa_es GRRRKRPVQK GKPPYSYIAL ISMAIANSPE RKLTLGGIYK FIMDRFPYYR DRDKKWQNSI RHNLTLNDCF VKIPREPGRP
BfFoxEb_es NRRRRKQRPA GKPPYSYVAL ITMAIVNSPE RKTTLAGIYK FIMDHFPYYR EADKKWQNSI RHNLTLNDCF VKLARHPNRP
BfFoxEc_es NRRRRKQRPA GKPPYSYVAL ITMAIVNSPE RKTTLAGIYK FIMDHFPYYR EADKKWQNSI RHNLTLNDCF VKLARHPNRP
BfFoxEd_e- NRRRRKQRPA GKPPYSYVAL ITMAIVNSPE RKTTLAGIYK FIMDHFPYYR EADKKWQNSI RHNLTLNDCF VKLARHPNRP
BfFoxEe_e- NRRRRKQRPA GKPPYSYVAL ITMAIVNSPE RKTTLAGIYK FIMDHFPYYR EADKKWQNSI RHNLTLNDCF VKLARHPNRP
BfFoxEf_e- NRRRRKQRPA GKPPYSYVAL ITMAIVNSPE RKTTLAGIYK FIMDHFPYYR EADKKWQNSI RHNLTLNDCF VKLARHPNRP
BfFoxEg_e- NRRRRKQRPA GKPPYSYVAL ITMAIVNSPE RKTTLAGIYK FIMDHFPYYR EADKKWQNSI RHNLTLNDCF VKLARHPNRP
BfFoxEh_e- NRRRRKQRPA GKPPYSYVAL ITMAIVNSPE RKTTLAGIYK FIMDHFPYYR EADKKWQNSI RHNLTLNDCF VKLARHPNRP
BfFoxEi_e- NRRRRKQRPA GKPPYSYVAL ITMAIVNSPE RKTTLAGIYK FIMDHFPYYR EADRKWQNSI RHNLTLNDCF VKLARHPNRP
MmFoxA1-AA AKTFKRSYPH AKPPYSYISL ITMAIQQAPS KMLTLSEIYQ WIMDLFPYYR QNQQRWQNSI RHSLSFNDCF VKVARSPDKP
MmFoxB1-NP PRPGRNTYSD QKPPYSYISL TAMAIQSSPE KMLPLSEIYK FIMDRFPYYR ENTQRWQNSL RHNLSFNDCF IKIPRRPDQP
MmFoxC1-Q6 PYTPQPQPKD MVKPPYSYIA LITMAIQNAP DKKITLNGIY QFIMDRFPFY RDNKQGWQNS IRHNLSLNEC FVKVPRDDKK
MmFoxD1-NP GTGGGAKNPL VKPPYSYIAL ITMAILQSPK KRLTLSEICE FISSRFPYYR EKFPAWQNSI RHNLSLNDCF VKIPREPGNP
MmFoxD2-O3 SGGAATRSPL VKPPYSYIAL ITMAILQSPK KRLTLSEICE FISGRFPYYR EKFPAWQNSI RHNLSLNDCF VKIPREPGNP
MmFoxD3-Q6 LTPNKPKNSL VKPPYSYIAL ITMAILQSPQ KKLTLSGICE FISNRFPYYR EKFPAWQNSI RHNLSLNDCF VKIPREPGNP
MmFoxD4-NP PTTTADGPQP AKPPYSYIAL ITMAILQSPH KRLTLSGICA FISGRFPYYR RKFPAWQNSI RHNLSLNDCF VKIPREPGHP
MmFoxE1-CA GRRRKRPLQR GKPPYSYIAL IAMAIAHAPE RRLTLGGIYK FITERFPFYR DNPKKWQNSI RHNLTLNDCF LKIPREAGRP
MmFoxE3-Q9 -KRRRRPLQR GKPPYSYIAL IAMALAHAPG RRLTLAAIYR FITERFAFYR DSPRKWQNSI RHNLTLNDCF VKVPREPGNP
DmFoxD59A- DGSGSSGGPL VKPPYSYIAL ITMAILQSPH KKLTLSGICD FIMSRFPYYK DKFPAWQNSI RHNLSLNDCF IKVPREPGNP
NvFoxD1-AB GKKRTHRKCR RRPPYSYIAL IAMAVQNSPE KRLTLDGICK FIRDRFPFYR ETYPSWKICI RNNLSLNDCF IKTGIKSDEP
CsFoxD-BAB EDYSKESKTN VKPPYSYIAL ITMAILQSPD KKLTLSGICD FIMNRFPYYK EKFPAWQNSI RHNLSLNDCF VKIAREPGNP
SpFoxD-ABB TADDKKKAIS VKPPYSYIAL ITMSILQSPQ KRLTLSGICE FIMNRFPYYR EKFPVWQNSI RHNLSLNDCF VKIPREPGNP
XtFoxD3-AA -MQNKPKNSL VKPPYSYIAL ITMAILQSPQ KKLTLSGICE FISNRFPYYR EKFPAWQNSI RHNLSLNDCF VKIPREPGNP
DrFoxD3-NP PMQNKPKSSL VKPPYSYIAL ITMAILQSPQ KKLTLSGICE FISNRFPYYR EKFPAWQNSI RHNLSLNDCF VKIPREPGNP
GgFoxD3-NP AGQSKPKSSL VKPPYSYIAL ITMAILQSPQ KKLTLSGICE FISNRFPYYR EKFPAWQNSI RHNLSLNDCF VKIPREPGNP
DrFoxD1-AA TGDKPGKNAL VKPPYSYIAL ITMAILQSPK KRLTLSEICE FISNRFPYYR EKFPAWQNSI RHNLSLNDCF VKIPREPGNP
XtFoxD1-Q6 TGGGGGRSAL VKPPYSYIAL ITMAILQSPK KRLTLSEICE FISNRFPYYR EKFPAWQNSI RHNLSLNDCF VKIPREPGNP
DrFoxD5-NP STVAPKQSSS VKPPYSYIAL ITMAILQSPM KKLTLSGICD FISNKFPYYK EKFPAWQNSI RHNLSLNDCF IKIPREPGNP
GgFoxD2-NP GGGGGGKNPL VKPPYSYIAL ITMAILQSPK KRLTLSEICE FISGRFPYYR EKFPAWQNSI RHNLSLNDCF VKIPREPGNP