Table e-1

Clinical profile of the patients including sex, age at the time of pre-operative functional MRI (fMRI) study, age at onset of epilepsy, antiepileptic drugs (AEDs) used by the patient including those at the time of the pre-operative (i.e. first) fMRI study shown in italics and those at the time of the post-operative fMRI study shown in bold face, MRI findings, pathological findings, and surgical outcome. CA4 FCD, focal cortical dysplasia of the end folium; CBZ, carbamazepine; CLB, clobazam; CNZ, clonazepam; DNET, dysembryoblastic neuroepithelial tumor; F, female; Gliosis NOS, gliosis not otherwise specified; GBP, gabapentin; Gang, ganglioglioma; HS, hippocampal sclerosis; L, Left; LEV, levetiracetam; LTG, lamotrigine; M, male; mos, months; MTS, mesial temporal sclerosis; OXC, oxcarbamazepine; PB, Phenobarbital; PHT, phenytoin; PRM, primidone; R, right; T, temporal lobe; TPM, topirmate; VPA, valproic acid; yrs, years. Patients 1-10 had left temporal lobe epilepsy while patients 11-19 had right temporal lobe epilepsy.

Pt /

Sex

/ Age at 1st fMRI (yrs) / Epilepsy onset(yrs) / AEDs / MRI /

Pathology

/ Follow- up (mos) /

Outcome

(Engel class)
1 / M / 36 / 17 / PHT,CLB / LMTS / L HS / 12 / I
2 / M / 50 / 48 / LEV, LTG, TPM
CNZ / N / L HS / 12 / I
3 / F / 35 / 9 / LEV, CBZ, PRM / L MTS / L HS / 16 / I
4 / F / 19 / 14 / LEV, CBZ, CLB / L MTS / L HS plus
CA4 FCD / 31 / I
5 / M / 34 / 30 / LTG,TPM / L T Gang. / L T Gang. / 24 / I
6 / F / 56 / 4 / TPM,LEV,VPA / L MTS / L HS / 14 / I
7 / M / 29 / 23 / PB,LEV, CLB
VPA, TPM,PHT GBP / N / N / 30 / III
8 / M / 23 / 19 / CBZ,VPA,PHT CLB / N / N / 20 / II
9 / M / 27 / 8 / PB, PHT, CBZ
VPA, GBP, LTG
TPM, PRM, OXC / L MTS / L HS / 12 / II
10 / F / 47 / 28 / VPA, CLB, PHT / N / Gliosis NOS / 18 / I
11 / M / 27 / 10 / PHT, GBP, CBZ
TPM, LEV / N / R HS / 15 / I
12 / F / 30 / 15 / CBZ,CLB,LTG / R MTS / R HS / 30 / I
13 / F / 40 / 20 / VPA, PHT, TPM
CBZ, LEV, LTG / R T DNET / R T DNET / 12 / I
14 / F / 37 / 31 / TPM, CBZ / R MTS / R HS / 24 / I
15 / M / 34 / 14 / PB, TPM, CBZ
LEV / R MTS / R HS / 12 / I
16 / M / 45 / 10 / PRM, TPM, CBZ
VPA, LEV, PB
CLB / N / R HS / 24 / I
17 / F / 35 / 10 / PB,VPA, TPM
CBZ, CLB / R MTS / R HS / 36 / I
18 / F / 46 / 42 / CBZ, CLB, LEV
PHT / R MTS / R HS / 22 / II
19 / F / 24 / 1.5 / PHT,PB, CNZ
VPA, CBZ,TPM / R MTS / R HS / 17 / II

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