The Evolution of the Cell

The Cells That Changed the Earth

Some of the oldest cells on Earth are single-cell organisms called bacteria. Fossil records indicate that mounds of bacteria once covered young Earth. Some began making their own food using carbon dioxide in the atmosphere and energy they harvested from the sun. This process (called photosynthesis) produced enough oxygen to change Earth's atmosphere. Soon afterward, new oxygen-breathing life forms came onto the scene. With a population of increasingly diverse bacterial life, the stage was set for some amazing things to happen.

Bacteria are single-celled organisms with a circular DNA molecule and no organelles.

The Endosymbiotic Theory

There is compelling evidence that mitochondria and chloroplasts were once primitive bacterial cells. This evidence is described later in the article. How did this theory get its name? Symbiosis occurs when two different species benefit from living and working together. When one organism actually lives inside the other it's called endosymbiosis.

We think that around 2 billion years ago,the only living organisms on Earth were prokaryotes, single-celled organisms lacking membrane-bound organelles. Let's look closely at three single-celled organisms living at the time. One was a big, simple blob-like cell with the ability to absorb things by wrapping its cell membrane around them. Another was a bacterial cell that converted solar energy into sugar molecules through photosynthesis. A third used oxygen gas to break down materials like sugar and release its energy into a form useful for life activities. The blob cells would occasionally absorb the little photosynthetic bacteria. These bacteria then lived inside the blob and divided like they always had, but their existence became linked. If you stumbled upon this living arrangement, you might just think that the whole thing was one organism, that the green photosynthetic bacteria were just a part of the blob that performed one of its life functions, just like your heart is a part of you that performs the function of pumping your blood. This process of cells living together is called endosymbiosis, one organism living inside another. But the endosymbiosis didn't stop there. What would happen if the other bacteria moved in, too? Now the cells of this species started becoming highly complex.They were big and full of intricate structures that we call chloroplasts and mitochondria.These structures work together to harness sunlight, make sugar, and break down that sugar using the oxygen that right around this time started to appear in the Earth's atmosphere.Organisms absorbing other organisms was one way species adapted to the changing environmental conditions of their surroundings. This little story highlights what biologists call the endosymbiotic theory, the current best explanation of how complex cells evolved.

Evidence of the Endosymbiotic Theory

There’s a lot of evidence that supports this theory, but let’s look at three main pieces. First, the chloroplasts and mitochondria in our cells multiply the very same way as those ancient bacteria. If you destroy these structures in a cell, no new ones will appear. The cell can’t make them, they can only make more of themselves. Mitochondria and chloroplasts therefore can replicate their own DNA and direct their own division. This means that within a eukaryotic cell, mitochondria and chloroplasts can make additional copies of themselves if necessary.

The second piece of evidence… Chloroplasts and mitochondria both contain their own DNA and ribosomes. There DNA has a circular structure that is strikingly similar to the DNA of the ancient bacteria and it also contains many similar genes. The ribosomes also look and function the same way as those found in ancient bacteria.

Lastly, think about the membranes involved in the engulfing process. Chloroplasts and mitochondria both have two membranes surrounding them, an inner and outer membrane. Their inner membrane contains some particular lipids and proteins that are not present in the outer membrane. Why is that significant? Because their outer membrane used to belong to the original bacterial cell. When they were engulfed in the endosymbiosis process, they got wrapped in that membrane and kept their own membrane as their inner one. Surely enough, those same lipids and proteins are found on the membranes of the ancient bacteria.

Biologists now use this theory to explain the origin of the vast variety of eukaryotic organisms.

The Evolution of the Cell Questions

1.  What is the Endosymbiotic theory?

2.  Draw a cartoon about the theory.

3.  How did this theory get its name?

4.  How do mitochondria and chloroplasts have striking similarities to bacterial cells? Give at least 3 reasons.

5.  Do you believe that modern day mitochondria and chloroplast really did evolve from free-living bacteria? Explain why or why not.