Cell Biology Course Syllabus (2015-9-10)
Teaching load each week: 2 X 90min lectures + 2 X 90min discussion classes.
There will be two midterm exams and one final exam, 40%, 30%, and 30%.
Textbook will be Lodish “Molecular and Cellular Biology (7th edition)”.
Each week, there will be 2 lectures (90 minutes per lecture) and 2 discussion classes (90 minutes each). The discussion class can cover an original research paper..
WEEK1: Sept14-18 ----- Yue Zhou (Jiao Tong University)
Sept 15Tuesday (10:00-11:40 am)
Introduction to Cell Biology
Chapters 1, 2, 3, 4, 6, 7
Sept 18Friday (10:00-11:40 am)
Membrane structure, cellular compartments and protein sorting
Chapters 10, 13
WEEK2: Sept 21-25 ---- Yue Zhou and Weiliang Xia (Jiao Tong University)
Sept 22Tuesday
Endoplasmic reticulum and protein synthesis
Chapter13
Sept 25Friday
Energy conversion: Mitochondria and chloroplasts
Chapter 12
WEEK3: Sept 28- Oct 2 ----- Yue Zhou(Jiao Tong University)
Sept 29Tuesday (90 min)
Protein trafficking from Endoplasmic Reticulum to Golgi
Chapter 14
WEEK 4: Oct 5 –Oct 10 ----- Weiliang Xia (Jiao Tong University)
Oct 10Saturday (National Day Holiday, move to Oct 10)
Endocytosis and Exocytosis
Chapter 14
WEEK 5: Oct 12-16Yue Zhou and Weiliang Xia (Jiao Tong University)
Oct 13Tuesday
Culturing, Visualization and Perturbing Cells
Chapter 9
Oct15 Thursday
Discussion classI & II: Super-resolution microscopy (90 min each)
Oct 16Friday (90 min)
Manipulating Proteins, DNA and RNA
Chapter 5
WEEK6: Oct 19-23,Le Ma (Thomas Jefferson University)
Oct 20 Tuesday
Cytoskeleton: assembly and dynamics (90 min)
Chapter 17, 18
Oct 22 Thursday
Discussion class I & II: Dynamics of polymer assembly (90 min each)
Oct 23 Friday
Cytoskeleton: regulation (90 min)
Chapter 17, 18
WEEK7: Oct 26-30 ---- Le Ma (Thomas Jefferson University)
Oct 27 Tuesday
Molecular Motors (90 min)
Chapter 17, 18
Oct 29 Thursday
Discussion class I & II: Generation of neuronal cell polarity (90 min each)
Oct 30 Friday
Mitosis, cell shape and movement (90 min)
Chapter 20, 23
Week 8Nov 2- Nov 6 Yue Zhou and Weiliang Xia (Jiao Tong University)
Nov 3Tuesday (90 min) ,First midterm
November 5 Thursday (90min)
Discussion classI & II: Caspases (90 min each)
Nov 6Friday (90 min)
Cell death: apoptosis, necrosis and autophagy
Chapter 21
WEEK 9: Nov 9-Nov 13 Yue Zhou and Weiliang Xia (Jiao Tong University)
November 10 Tuesday (90 min)
Sexual reproduction and stem cells
Chapter 21
WEEK10: Nov 16- Nov 20 ----- Wei Li (USC)
Nov 17, Tuesday
Signal Transduction: Concept and Mechanism
Chapter 15, 16
Nov 19, Thursday
Discussion class I & II: Studies on cell signaling: today and tomorrow(90 min each)
WEEK11: Nov 23- Nov 27, Wei Li (USC)
Nov 23Monday 18:00-19:40
Signal Transduction: New Progress
Chapter 15, 16
Nov 24, Tuesday
Cell Cycle Progression and Control of Cell Proliferation
Chapter 19
Nov 26, Thursday
Discussion class I & II: The challenges in cancer diagnosis and treatment (90 min each)
Nov 27, Friday
Cell Transformation and Cancer;
Oncogenes and Tumor Suppressor Genes
Chapter 24
WEEK12: Nov 30-Dec 4 Yue Zhou and Weiliang Xia (Jiao Tong University)
Dec 1Tuesday (90 min) ,Second midterm
December 4 Friday (90 min) Weiliang Xia
Cell Biology Topics
WEEK13: Dec 7-Dec 11 ----Liming Li (Northwestern University)
Dec 8 Tuesday
Ion channels and transporters (90 min)
Chapter 11
Dec 10 Thursday
Discussion class I & II: Channelrhodopsin and application (90 min each)
Dec 11Friday
Synaptic structure and synapse formation (90 min)
Chapter 22
Week14----- Dec 14-18 Liming Li (Northwestern University)
Dec 15 Tuesday
Cell-cell adhesion and tight junctions (90 min)
Chapter 20
Dec 17 Thursday
Discussion class I & II: Cell degeneration and disease (90 min each)
Dec 18 morning Friday
Gap junctions and extracellular matrix(90 min)
Chapter 20
WEEK15: Dec 21-25--- Yue Zhou and Weiliang Xia (Jiao Tong University)
December 22Tuesday (90 min)
Cellular responses induced by tissue engineering biomaterials
Early January ----- Final Exam