Table 4: Differentially Expressed Genes in Leiomyoma of African Americans and Caucasians

Table 4: Differentially expressed genes in leiomyoma of African Americans and Caucasians.

Gene BankSymbol F. Change P value Function
NM_005803FLOT10.0008 4.7signal transduction
NM_003930SCAP20.00134.4signal transduction
O14632HIPK30.00023.2signal transduction
P43115PTGER30.00763.1signal transduction
SOS10.00063.0signal transduction
NM_006449CDC42EP30.00642.7signal transduction
NM_006549CAMKK20.00042.7signal transduction
P17964RAP2B0.00062.6signal transduction
Q92844TANK0.00002.6signal transduction
NM_000267NF10.00042.6signal transduction
L35253MAPK140.00112.5signal transduction
Q16825PTPN210.00472.5signal transduction
MAP4K50.00002.4signal transduction
P04156PRNP0.00002.3signal transduction
NM_006420ARFGEF20.00262.3signal transduction
P27986PIK3R10.00452.2signal transduction
NM_002835PTPN120.00012.2signal transduction
Q15382RHEB0.00042.2signal transduction
Q9ULC3RAB230.00002.2signal transduction
P39687ANP32A0.00242.1signal transduction
M37712CDC2L20.00222.1signal transduction
P26442AMFR0.01002.1signal transduction
M33336PRKAR1A0.00012.1signal transduction
CALM10.00052.1signal transduction
NM_001387DPYSL30.00772.0signal transduction
P04901GNB10.00022.0signal transduction
Q9UPA1G3BP20.00012.0signal transduction
NM_004253PLAA0.00692.0signal transduction
Q13614MTMR20.00092.0signal transduction
NM_006861RAB350.00552.0signal transduction
KIAA1053 proteinSAMD40.00822.0signal transduction
O95704APBB30.00070.5signal transduction
NM_005456MAPK8IP10.00630.5signal transduction
P17612PRKACA0.00380.5signal transduction
Q9Y6J0CABIN10.00420.5signal transduction
FLJ392490.00040.5signal transduction
NM_012395PFTK10.00040.5signal transduction
NM_003331TYK20.00140.5signal transduction
L13738ACK10.00070.5signal transduction
NM_005160ADRBK20.00790.5signal transduction
P20336RAB3A0.00520.4signal transduction
NM_004723ARHGEF20.00100.4signal transduction
Q15486SMA30.00220.3signal transduction
P17010ZFX0.00003.7transcription
TCF80.00003.3transcription
CDC5L0.00102.8transcription
O43311MBNL10.00002.6transcription
O00712NFIB0.00002.6transcription
NM_002040GABPA0.00462.4transcription
NM_003670BHLHB20.00452.3transcription
U18671STAT20.00102.2transcription
NM_006625FUSIP10.00002.2transcription
CREB10.00012.2transcription
Q9Y2S3TAF9L0.00002.1transcription
AF040963MXD40.00020.5transcription
NM_012384GMEB20.00820.5transcription
Q9UEG5CIC0.00350.5transcription
Q9Y6K9IKBKG0.00420.5transcription
Q15737SUPT6H0.00190.5transcription
L41066NFATC40.00950.5transcription
O95503CBX60.00020.5transcription
Q14656CXorf120.00120.4transcription
NM_006532ELL0.00190.4transcription
NM_000937POLR2A0.00470.3transcription
MBNL20.00004.4RNA processing
Q13243SFRS50.00034.4RNA processing
NM_005885TEB40.00033.3RNA processing
P34096RNASE40.00942.3RNA processing
O43809CPSF50.00032.1RNA processing
HNRPH10.00822.1RNA processing
Q15428SF3A20.00060.5RNA processing
NM_006711RNPS10.00200.5RNA processing
P26196DDX60.00820.5RNA processing
Q9Y388CGI-790.00040.5RNA processing
HIP140.00522.2tumor suppressors
Q07157TJP10.00292.1tumor suppressors
O95997PTTG10.00960.4tumor suppressors
NM_012141DDX260.00100.3tumor suppressors
P36406ARFD10.00643.0translation
EIF4EBP20.00052.9translation
P10159EIF5A0.00002.6translation
P26438ARF60.00002.6translation
15E1.20.00102.4translation
NM_005907MAN1A10.00012.2translation
P23411RPL380.00832.2translation
NM_001969EIF50.00012.1translation
P06396GSN0.00792.0translation
NM_005494DNAJB60.00002.0translation
NM_006048UBE4B0.00372.0translation
NM_004184WARS0.00080.5translation
NM_000345SNCA0.00010.3translation
NM_000141FGFR20.001612.7cell receptors
P36897TGFBR10.00064.8cell receptors
D50683TGFBR20.00613.5cell receptors
NM_005761PLXNC10.00203.5cell receptors
O60462NRP20.00222.4cell receptors
M59964KITLG0.00772.1cell receptors
O94816FZD70.00442.0cell receptors
M26062IL2RB0.00220.5cell receptors
Q13491GPM6B0.00593.1cell surface antigens
M59040CD440.00162.7cell surface antigens
Q04900CD1640.00172.3cell surface antigens
P07585DCN0.00652.0cell surface antigens
P30408TM4SF10.00402.0cell surface antigens
NM_000733CD3E0.00800.5cell surface antigens
NM_002456MUC10.00800.5cell surface antigens
M19154TGFB20.00522.1growth factor
NM_004883NRG20.00690.5growth factor
MT1E0.00112.4protein binding
O75083WDR10.00332.4protein binding
Q9NZ08ARTS-10.00772.2protein binding
PNAS-40.00182.2protein target
NM_018846SBBI260.00002.2protein binding
Q9NUP9LIN7C0.00002.1protein binding
DDX3X0.00002.1protein binding
Q9NVA2FLJ108490.00233.6cell cycle
NM_018310BRF20.00122.8cell proliferation
NM_022731NUCKS0.00202.5cell cycle
O15172PSPHL0.00682.4cell cycle
NM_016250NDRG20.00152.3cell cycle
P54826GAS10.00122.1cell cycle
Q14004CDC2L50.00012.0cell cycle
NM_005255GAK0.00010.5cell cycle
NM_003644GAS70.00460.5cell cycle
O14569101F60.00230.4cell cycle
PTEN0.00883.0apoptosis
Q07820MCL10.00062.9apoptosis
NM_013436NCKAP10.00362.6apoptosis
P29466CASP10.00812.3apoptosis
BCLAF10.00012.1apoptosis
NM_016315GULP10.00002.0apoptosis
NM_006595API50.00002.0apoptosis
BCL2L10.00830.5apoptosis
Q01082SPTBN10.00004.5cytoskeleton/motility proteins
NM_005909MAP1B0.00163.0cytoskeleton/motility proteins
P35749MYH110.00052.9cytoskeleton/motility proteins
Q13642FHL10.00202.6cytoskeleton/motility proteins
Q9NYL9TMOD30.00022.4cytoskeleton/motility proteins
PICALM0.00012.3cytoskeleton/motility proteins
NM_007124UTRN0.00122.1cytoskeleton/motility proteins
HIP1R0.00010.5cytoskeleton/motility proteins
NM_006158NEFL0.00060.1cytoskeleton/motility proteins
ITGA10.00042.7cell adhesion
PLEKHC10.00032.3cell adhesion
P35222CTNNB10.00512.0cell adhesion
NM_003156STIM10.00580.5cell adhesion
Q9Y368PARVB0.00020.3cell adhesion
NM_001219CALU0.00602.0extracellular transport
P55058PLTP0.00440.5extracellular transport
P07988SFTPB0.00210.5extracellular transport
NM_004995MMP140.00334.0protein turnover
NM_013381TRHDE0.00852.3protein turnover
P06870LAMP10.00092.0protein turnover
NRP20.00152.1protein kinase activity
LTBP10.00280.5protein kinase activity
LRRK10.00150.3protein kinase activity
DKFZP564M1820.00150.5protein catabolism
Q9H9C5USP360.00330.5protein catabolism
NM_022350LRAP0.00040.3protein catabolism
NM_000849GSTM30.00028.0metabolism
PTGIS0.00902.6metabolism
NM_001918DBT0.00072.4metabolism
NM_000850GSTM40.00482.4metabolism
NM_016286DCXR0.00442.1metabolism
O15269SPTLC10.00052.1metabolism
P06733ENO10.00452.1metabolism
NM_001921DCTD0.00002.1metabolism
NM_006759UGP20.00562.1metabolism
SCP20.00482.1metabolism
P48449LSS0.00810.5metabolism
P40967SILV0.00410.5metabolism
Q05932FPGS0.00300.5metabolism
NM_000203IDUA0.00030.5metabolism
P05186ALPL0.00910.5metabolism
PLA2G60.00040.4metablism
P08294SOD30.00050.4metabolism
Q9UFW9CLIC40.00203.4trafficking proteins
P54920SNAP230.00013.1trafficking proteins
AF112465OGN0.00283.1trafficking proteins
P14543NID0.00842.9trafficking proteins
P08240SRPR0.00002.8trafficking proteins
CYBRD10.00182.8trafficking proteins
O15126SCAMP10.00062.7trafficking proteins
NM_006544SEC10L10.00002.6trafficking proteins
CALD10.00002.6trafficking proteins
Q9Y587AP4S10.00002.5trafficking proteins
TRA10.00252.4trafficking proteins
NM_003763STX160.00022.4trafficking proteins
NM_007047BTN3A20.00252.4trafficking proteins
Q15836VAMP30.00002.4trafficking proteins
NM_006364SEC23A0.00022.1trafficking proteins
NM_006364SEC23A0.00022.1trafficking proteins
NM_002268KPNA40.00012.1trafficking proteins
P53621COPA0.00022.0trafficking proteins
NM_003304TRPC10.00062.0trafficking proteins
RNP240.00212.0trafficking proteins
ATP6V0E0.00052trafficking proteins
NM_000725CACNB30.00130.5trafficking proteins
NM_004177STX3A0.00070.5trafficking proteins
NM_003624RANBP30.00000.5trafficking proteins
O00499BIN10.00300.5trafficking proteins
L22548COL18A10.00230.5trafficking proteins
NM_003045SLC7A10.00730.5trafficking proteins
NM_003488AKAP10.00870.4trafficking proteins
NM_016287HP1-BP740.00003.9DNA packaging
L20298CBFB0.00982.2DNA binding
P49454CENPF0.00840.4DNA binding
GRINL1A0.00452.0maintenance of ER location
NM_019892INPP5E0.00590.5phosphatase activity
KIAA02760.00022.1nucleus
Q9BQQ3GORASP10.00090.4Golgi apparatus
HyalphaNC00 0.00173.4defense response
Q09160HLA-A0.00722.3defense response
P02686MBP0.00132.1defense response
MHC-1A0.00682.1defense response
M11886HLA-C0.00102.9defense response
SSH-30.00096.6not classified
Q9NXB3CDKAL10.00025.8not classified
PALMD0.00523.8not classified
NM_016613DKFZp434L1420.00033.6not classified
NM_001862COX5B0.00053.5not classified
Q9P007HSPC1570.00723.2not classified
MED80.00163.2not classified
Q9NS11C14orf1170.00002.7not classified
C6orf620.00002.7not classified
Q9NVV2FLJ104900.00562.6not classified
MT1K0.00612.6not classified
NEK90.00212.5not classified
MGC154190.00472.5not classified
LAP1B0.00002.3not classified
SP3290.00002.2not classified
O94968KIAA08940.00992.2not classified
NM_017548H410.00012.1not classified
SWAP700.00312.0not classified
SCARB20.00012.0not classified
Q9Y471CMAH0.00582.0not classified
NM_030755TXNDC0.00042.0not classified
O75071KIAA04940.00032.0not classified
NM_019018FLJ111270.00412.0not classified
CYB5-M0.00002.0not classified
MAP3K20.00032.0not classified
FLJ208960.00180.5not classified
TM6SF20.00110.5not classified
NM_024094MGC55280.00940.5not classified
FLJ001330.00280.5not classified
TPSB20.00530.5not classified
O75781PALM0.00140.5not classified
MGC298160.00000.5not classified
EZI0.00950.5not classified
TST0.00070.5not classified
KIAA0365 SFRS140.00110.5not classified
LOC2545310.00080.5not classified
TPSB10.00450.5not classified
FLJ118710.00260.5not classified
TBC1D30.00150.5not classified
Q9P0T5LOC512360.00270.5not classified
NM_017670OTUB10.00020.5not classified
TPSB20.00120.4not classified
NM_019005FLJ203230.00060.4not classified
Q9H008LHPP0.00040.4not classified
KIAA0792 KIAA07920.00530.4not classified
Q15004KIAA01010.00140.4not classified
NM_017814FLJ201740.00290.4not classified
FLJ228430.00890.4not classified
Q9NXC7PQLC20.00940.3not classified
SMA30.00220.3not classified

The list of 266 differentially expressed genes in leiomyoma of African Americans as compare with Caucasians selected at P<0.001 and 2-fold cut-off, in part presented as Table 1. Partial list of genes from several functional categories differentially expressed in leiomyomas of African Americans as compared to Caucasians as illustrated in figure 1, selected based on p≤0.001 and 2-fold cutoff change (F. Change) as described in materials and methods.