Table 3:Individual Patient Data

Table 3:Individual Patient Data

Patient / Age / GPA / Systemic Disease Diagnosed / CNS Disease Diagnosed / Initial Tx / GKSRS Session Date / Tumors Treated / Radiation / Adjuvant Therapy / Follow-up / Date of Death / Comment
Sarcoma 1 / 58 / 3.5 / 12/1998 / 12/1998 / Surgical Resection / 3/31/1999 / 1 / 15Gy to 50% isodense line / WBRT / No radiographic progression 6/28/1999 / 6/26/2000
Sarcoma 2 / 46 / 4.0 / 04/2002 / 04/2002 / GKSRS / 5/22/2002 / 1 / 18Gy to 53% isodense line / Chemo-therapy / No radiographic progression 8/26/2002 / 11/19/2003
Sarcoma 3 / 32 / 3.0 / 6/28/2005 / 9/30/2008 / GKSRS / 10/8/2008 / 2 / 15Gy to 50% isodense line / None / NA / 12/12/2008 / Initial GKSRS planned in two-stages, no progression between sessions
Sarcoma 3 / 10/15/2008 / 2 / 15Gy to 50% isodense line,
17Gy to 57% isodense line / None / Enlargement of 1 treated tumor on 11/19/2008 MRI
Sarcoma 4 / 57 / 3.5 / 03/2005 / 9/22/2008 / Surgical Resection / 10/20/2008 / 1 / 16Gy to 50% isodense line / Chemo-therapy / No radiographic progression on 5/19/2009 / NA
Prostate 1 / 66 / 2.5 / Unknown / Unknown / WBRT / 7/21/2001 / 1 / 19Gy to 50% isodense line / None / Radiographic progression of non-treated tumor 8/2/2001 / 12/13/2001
Prostate 2 / 67 / 3.0 / 08/2004 / 3/26/2005 / GKSRS / 4/4/2005 / 2 / 20Gy to 50% isodense line,
16Gy to 45% isodense line / Chemo-therapy / Radiographic progression of treated tumor 6/8/2005 / 6/29/2005
Thyroid 1 / 63 / 3.0 / 07/2000 / 04/2003 / Surgical Resection / 4/16/2003 / 2 / 18Gy to 54% isodense line,
20Gy to 60% isodense line / None / No radiographic progression of treated lesions-new tumor on MRI along biopsy tract / 9/8/2005 / Second GKSRS for new tumor
Thyroid 1 / 7/30/2003 / 1 / 17.5Gy to 50% isodense line / None / Radiographic progression of 1 tumor treated in first GKSRS session-3/16/2004
Thyroid 2 / 58 / 3.5 / 11/2006 / 5/2/2008 / GKSRS / 5/27/2008 / 1 / 18Gy to 50% isodense line / None / No radiographic progression on 3/24/2009 / NA
Thyroid 3 / 53 / 3.5 / 6/26/2005 / 8/18/2008 / GKSRS / 9/30/2008 / 1 / 18Gy to 62% isodense line / WBRT-only received 1 fraction / No radiographic progression on 3/24/2009 / 6/24/2010
Endometrial 1 / 55 / 3.5 / 06/1996 / 10/8/1996 / Surgical Resection / 12/4/1996 / 1 / 16Gy to 50% isodense line / None / No radiographic progression / 1/15/1997
Endometrial 2 / 70 / 3.0 / 01/2003 / 2/1/2005 / GKSRS / 2/17/2005 / 1 / 18Gy to 50% isodense line / Chemo-therapy / No radiographic progression on 3/31/2005 / 7/25/2005
Endometrial 3 / 70 / 2.0 / 01/2002 / 6/9/2006 / WBRT / 11/20/2006 / 2 / 17Gy to 52% isodense line
20Gy to 60% isodense line / Chemo-therapy / Radiographic progression of 1 previously treated tumor on 1/30/2007 / 8/24/2007
Endometrial 4 / 58 / 2.5 / 01/2004 / 6/13/2007 / GKSRS / 7/26/2007 / 1 / 16Gy to 49% isodense line / None / No radiographic progression on 8/23/2007 / 8/24/2008
Endometrial 5 / 66 / 1.5 / 10/30/2007 / 10/30/2007 / GKSRS / 11/21/2007 / 2 / 18Gy to 54% isodense line / Chemo-therapy / No radiographic progression on 10/21/2008 / NA
Ovarian 1 / 66 / 2.5 / 11/1999 / 10/2000 / WBRT- 40Gy in 10 fractions / 4/23/2001 / 1 / 20Gy to 52% isodense line / Chemo-therapy / Radiographic progression of treated tumor in 08/2001 / 6/8/2002
Ovarian 1 / 9/5/2001 / 1 / 20Gy to 50% isodense line / None / No radiographic progression 11/15/2001
Ovarian 2 / 67 / 3.0 / 01/1994 / 09/2001 / Surgical Resection / 12/17/2001 / 1 / 20Gy to 50% isodense line / Chemo-therapy / No radiographic progression on 11/26/2002 / 3/5/2003
Ovarian 3 / 42 / 4.0 / 05/2000 / 11/2001 / Surgical Resection / 2/13/2001 / 1 / 16Gy to 50% isodense line / Chemo-therapy / Radiographic progression of treated tumor on 5/13/2002 / 9/17/2003
Ovarian 3 / 11/6/2002 / 1 / 17Gy to 50% isodense line / None / No radiographic progression on 9/3/2003
Ovarian 4 / 56 / 3.5 / 01/1997 / 05/2004 / Surgical Resection / 6/24/2004 / 1 / 16Gy to 46% isodense line / Chemo-therapy / No radiographic progression on 5/7/2009 / NA
Ovarian 5 / 62 / 3.0 / 01/2004 / 11/2005 / IMRT / 2/13/2006 / 1 / 10Gy to 48% isodense line / None / No radiographic progression on 7/23/2006 / 8/6/2006
Ovarian 6 / 46 / 4.0 / 02/2006 / 11/17/2006 / GKSRS / 12/5/2006 / 1 / 18Gy to 52% isodense line / Chemo-therapy / Radiographic progression of treated tumor on 11/21/2007 / 1/29/2008
Ovarian 7 / 78 / 3.0 / Unknown / 9/11/2007 / Surgical Resection / 10/9/2007 / 1 / 15Gy to 46% isodense line / Chemo-therapy / New lesion on 9/19/2008 MRI / NA
Ovarian 7 / 9/30/2008 / 1 / 20Gy to 50% isodense line / None / No radiographic progression on 4/14/2009
Cervical 1 / 41 / 3.0 / Unknown / 4/15/2002 / GKSRS / 4/24/2002 / 1 / 17Gy to 50% isodense line / Chemo-therapy / No radiographic progression on 7/31/2002 / 12/16/2002
Cervical 2 / 43 / 3.0 / 6/23/2005 / 10/1/2007 / Surgical Resection / 10/23/2007 / 1 / 16Gy to 50% isodense line / None / No radiographic progression on 11/23/2007 / 1/26/2008
Esophageal 1 / 74 / 1.5 / 10/6/1998 / 10/6/1998 / GKSRS / 10/21/1998 / 2 / 18Gy to 50% isodense line / Chemo-therapy / Radiographic progression of treated tumor on 10/29/1999 / 4/20/2000
Esophageal 2 / 72 / 3.0 / 4/25/2000 / 4/25/2000 / Surgical Resection / 5/17/2000 / 2 / 18Gy to 45% isodense line for tumor bed
20Gy to 50% isodense line for second tumor / Chemo-therapy / New lesion on 9/19/2000, stable treated lesions / 3/7/2001
Esophageal 2 / 9/27/2000 / 1 / 18Gy to 48% isodense line / None / No radiographic progression on 10/20/2000
Esophageal 3 / 60 / 2.5 / 07/2001 / 9/1/2002 / WBRT / 12/18/2002 / 2 / 18Gy to 50% isodense line / Chemo-therapy / No radiographic progression on 10/11/2005 / 10/2/2006
Esophageal 4 / 60 / 3.0 / 02/2006 / 2/21/2007 / GKSRS / 3/6/2007 / 1 / 18Gy to 49% isodense line / WBRT / Radiographic progression of treated tumor on 10/25/2007 / 12/17/2007
Esophageal 5 / 69 / 2.0 / 3/11/2004 / 3/1/2008 / Surgical Resection / 4/22/2008 / 1 / 15Gy to 44% isodense line / Chemo-therapy / Radiographic progression of treated tumor on 10/2/2008 / NA
Esophageal 6 / 45 / 3.0 / 5/15/2003 / 5/15/2003 / GKSRS / 6/9/2003 / 2 / 20Gy to 50% isodense line
18Gy to 51% isodense line / Chemo-therapy / Radiographic progression of one treated tumor on 2/18/2004 / 4/18/2004
Bladder 1 / 81 / 2.0 / 6/24/2005 / 11/1/2006 / WBRT / 5/1/2007 / 4 / 20Gy to 60% isodense line / Chemo-therapy / Enlargment of two untreated lesions on 5/15/2007, stable appearance of treated lesions / 6/28/2007
Bladder 1 / 5/23/2007 / 2 / 14Gy to 50% isodense line / None / No radiographic followup
Bladder 2 / 78 / 1.5 / 01/2006 / 01/2006 / WBRT / 4/23/2007 / 2 / 15Gy to 50% isodense line / Chemo-therapy / Radiographic progression of one treated tumor on 7/23/2008 / 7/29/2008
Hepato-cellular 1 / 20 / 2.5 / Unknown / 7/26/2001 / GKSRS / 8/14/2001 / 2 / 20Gy to 50% isodense line / Chemo-therapy / Enlargement of untreated lesions on 9/13/2001, no radiographic progression of treated tumors / 7/19/2002 / Pt had 3rd GKSRS on 1/31/2002, treating 2 additional tumors, no radiographic progression on 4/8/2002
Hepato-cellular 1 / 10/4/2001 / 3 / 20Gy to 50% isodense line / None / Enlargement of untreated lesions on 12/20/2001, no radiographic progression of treated tumors
Hepato-cellular 1 / 1/31/2002 / 2 / Unknown / None / No radiographic progression on 4/8/2002
Pancreatic 1 / 65 / 1.0 / 6/27/1997 / 01/2004 / GKSRS / 2/4/2002 / 5 / 20Gy to 50% isodense line / Chemo-therapy / No radiographic progression one month post GKSRS / 3/11/2002
Testicular 1 / 17 / 3.0 / 02/2004 / 6/7/2004 / Surgical Resection / 7/7/2004 / 1 / 18Gy to 50% isodense line / WBRT, Chemo-therapy / No radiographic progression on 2/24/2009 / NA
Testicular 2 / 37 / 2.0 / 12/2002 / 11/2003 / Surgical Resection / 12/22/2004 / 5 / 16Gy to 50% isodense line / Gliasite Brachy-therapy, WBRT, Chemo-therapy / No radiographic progression on 1/25/2005 / 3/9/2005
Testicular 3 / 34 / 3.0 / 6/27/2005 / 11/2007 / GKSRS / 12/5/2007 / 1 / 15Gy to 50% isodense line / Chemo-therapy / Enlargement of treated lesion and new lesion on 2/27/2008 / 12/16/2008
Testicular 3 / 3/5/2008 / 2 / 15Gy to 50% isodense line / None / No radiographic followup