Table 2. Supplement.

The genotypefrequency ofSNP´s in the genes XPD, RAI, CD3EAP and ERCC1, located in the sub-region 19q13.3.

Trivial name / systematic name / Gene location / Position / Source of
identification / % Genotyped / MAF / HWE / TTF
p value / OS
p value
XPD-exon23 / *ERCC2 A>C / 18123137 / rs13181 / 96.5 / C:0.388 / 0.02 / 0.003 / 0.05
XPD-exon10 / *ERCC2 G>A / 18135477 / rs1799793 / 89.4 / A:0.367 / 0.78 / 0.58 / 0.66
XPD-exon6 / ERCC2 c.499A>C / CGA-CGC / 18136527 / rs238406 / 67 / T:0.466 / 0.92 / 0.12 / 0.45
XPD-intron5-1 / ERCC2 c.492-62T>A / Intron / 18136696 / rs238407 / 81 / T:0.434 / 0.69 / 0.08 / 0.42
XPD-5´2 / ERCC2 c.35-1958A>G / Near gene3 / 18144005 / rs2097215 / 70 / G:0.402 / 0.74 / 0.25 / 0.52
RAI-3'9 / NT_011109.15:g.18147886T>G / Near PPP1R13L 3´ / 18147886 / rs10422489 / 73 / G:0.387 / 0.81 / 0.57 / 0.82
RAI-3'4 / før PPP1R13L NT_011109.15:g.18150199A>G / Near PPP1R13L 3´ / 18150199 / rs4544343 / 73 / G.0.391 / 1.00 / 0.53 / 0.77
RAI-exon13-1 / PPP1R13L c.*475T>A / UTR-3 / 18151180 / rs6966 / 80 / T:0.151 / 0.30 / 0.15 / 0.65
RAI-intron8-1 / *PPP1R13L c.1882-1425A>G / Intron / 18159091 / rs1970764 / 94.5 / G:0.185 / 0.16 / 0.88 / 0.17
RAI-intron8-12 / PPP1R13L c.1881+756C>T / Intron / 18162599 / rs12986272 / 83 / A:0.253 / 0.68 / 0.39 / 0.69
RAI-intron1-7 / PPP1R13L c.21-1931G>T / Intron / 18171746 / rs10402584 / 73 / T:0.496 / 0.78 / 0.47 / 0.48
RAI-intron1-10 / PPP1R13L c.-21-2062G>A / Intron / 18171815 / rs10402393 / 81 / T:0.004 / 1.00 / 0.268 / 0.21
RAI-intron1-1 / PPP1R13L c.21-2169A>G / Intron / 18171984 / rs4572514 / 85.2 / C: 0.175 / 0.88 / 0.003 / 0.02
RAI-intron1-4 / PPP1R13L c.21-3291G>A / Intron / 18173106 / rs4803816 / 84.6 / T: 0.377 / 0.20 / 0.33 / 0.15
RAI-intron1-3 / PPP1R13L c.22+734A>G / Upstream / 18175739 / rs959457 / 85.5 / C: 0.171 / 0.68 / 0.007 / 0.04
RAI-intron1-11 / PPP1R13L c.-22+397C>G / Upstream / 18176078 / rs928911 / 86.4 / T: 0.052 / 1.00 / 0.05 / 0.30
RAI-intron1-5 / PPP1R13L c.-22+289T>C / Upstream / 18176178 / rs4803817 / 85.2 / G: 0.206 / 0.44 / 0.95 / 0.40
RAI-intron1-12 / NT_011109.15:g.18176179 / 18176179 / Nr106 / 90.2 / G: 0.215 / 0.74 / 0.80 / 0.77
RAI-5'1 / NT_011109.15:g.18176679A>G / Upstream / 18176679 / rs10412761 / 83.9 / G: 0.375 / 0.17 / 0.25 / 0.15
ASE1-exon1 / *CD3EAP c.468-21G>A / Upstream / 18178152 / rs967591 / 96.8 / A:0.177 / 0.27 / 0.002 / 0.004
ASE1-intron1-1 / CD3EAP c.22+29A>C / Intron / 18178221 / rs8113779 / 85.2 / T: 0.167 / 0.83 / 0.007 / 0.02
ASE1-intron-2-1 / CD3EAP / Intron / 18179548 / rs2013521 / 82.6 / T: 0.147 / 0.83 / 0.009 / 0.04
ASE1-exon3-1 / CD3EAP c.1264A>G / K261T / 18180220 / rs735482 / 84.6 / C: 0.143 / 0.86 / 0.03 / 0.03
ASE1-exon3-2 / CD3EAP c.1605A>G / K375E / 18180561 / rs762562 / 85.8 / G: 0.152 / 0.90 / 0.09 / 0.1
ASE1-exon3-3 / CD3EAP c.1668G>A / D396N / 18180624 / rs2336219 / 85.8 / A: 0.115 / 1.00 / 0.03 / 0.05
ASE1-exon3-6 / CD3EAP c.1998C>A / Q506K / 18180954 / rs3212986 / 78.3 / T: 0.254 / 0.69 / 0.02 / 0.03
ASE1-3'-1 / CD3EAP / 3`UTR / 18181304 / rs3212985 / 82.9 / C: 0.205 / 0.10 / 0.77 / 0.45
ASE1-3'-2 / CD3EAP / 3´UTR / 18181311 / rs1007616 / 82.9 / C: 0.379 / 0.11 / 0.78 / 0.66
ERCC1-intron5-1 / ERCC1 / Intron / 18187508 / rs3212969 / 82.6 / T: 0.137 / 0.04 / 0.13 / 0.04
ERCC1-intron4 / ERCC1 / Intron / 18190541 / rs3212961 / 85.2 / A: 0.133 / 0.81 / 0.07 / 0.11
ERCC1-exon4 / *ERCC1 c.500T>C / CD3EAP / 18191871 / rs317770 / 93.3 / G:0.377 / 0.26 / 0.2305 / 0.15
ERCC1-intron1 / ERCC1 c.-8+123G>T / Upstream / 18195134 / rs2298881 / 86.1 / A: 0.103 / 1.00 / 0.35 / 0.68
ERCC1-5'1 / NT_011109.15:g.18199439G>A / Upstream / 18199439 / rs1319052 / 83.2 / A: 0.350 / 0.06 / 0.003 / 0.05

* Previously published results (1). MAF: minor allele frequency

Reference List

(1) Vangsted A, Gimsing P, Klausen TW, Nexo BA, Wallin H, Andersen P, et al. Polymorphisms in the genes ERCC2, XRCC3 and CD3EAP influence treatment outcome in multiple myeloma patients undergoing autologous bone marrow transplantation. Int J Cancer 2007 Mar 1;120(5):1036-45.