Table 1. Possible Ser and Thr phosphorylation sites in human eEF-1A

Predicted Ser/Thr / Score / Context / Secondary Structure / Average Solvent Accessibility
S18 * / 0.992 / GHVDSGKST / s s - - -° - h h h / (1.1, 4.0, 38.3, 22.7, 10.9°, 0.0, 13.6, 4.8, 6.5), 11.3
S21 / 0.653 / DSGKSTTTG / - - - h h h h h / (22.7, 10.9, 0.0, 13.6, 4.8, 6.5, 5.6, 2.5, 0.0), 7.4
S107 / 0.854 / ITGTSQADC / h h - - - - - s s / (0.0, 20.7, 18.5, 39.2, 2.9, 33.6, 10.9 4.6, 0.5) 14.5
S157 * / 0.978 / NKMDSTEPP / s s - - - - - - - / (0.4, 23.8, 0.0, 11.5, 22.8, 2.1, 33.7, 34.1, 38.8) 18.6
S163 / 0.997 / EPPYSQKRY / - - - - - h h h h / (33.7, 34.1, 38.8, 27.6, 6.7, 34.7, 39.9, 18.6, 8.0) 26.9
S175 / 0.692 / VKEVSTYIK / h h h h h h h h h / (11.4, 42.9, 29.3, 2.6, 11.4, 35.3, 14.3, 0.4, 39.2) 20.8
S291 / 0.996 / TEVKSVEMH / s s s s s s s s s s / (9.1, 24.9, 1.3, 28.2, 27.1, 3.1, 24.5, 12.4, 35.7) 18.5
S316 * / 0.997 / VKNVSVKDV / s ------/ (0.0, 31.5, 44.6, 3.5, 21.9, 26.9, 48.4, 25.4, 2.7) 22.8
S329 / 0.975 / VAGDSKNDP / s s s s s - - - - / (0.0, 0.0, 0.0, 6.1, 20.9, 51.6, 43.4, 15.0, 25.7) 18.1
S383 * / 0.998 / IDRRSGKKL / s s - - - - s s s / (8.2, 14.2, 28.5, 29.1, 17.1, 11.8, 36.6, 38.5, 40.1) 24.9
S414 / 0.955 / MCVESFSDY / ------/ (2.7, 0.0, 3.5, 6.2, 9.0, 6.9, 16.7, 19.2, 5.6) 7.8
T72 / 0.552 / ERGITIDIS / ------/ (28.2, 8.7, 15.7, 23.2, 47.0, 53.3, 8.8, 28.6, 17.7) 25.7
T82 / 0.571 / WKFETSKYY / - - s s s s s s s / (13.6, 2.9, 2.7, 20.1, 9.4, 33.3, 34.1, 1.0, 20.6) 15.3
T217 / 0.662 / GWKVTRKDG / ------/ (36.0, 31.6, 18.3, 22.5, 31.0, 38.1, 27.5, 28.8, 8.4) 26.9
T227 / 0.567 / ASGTTLLEA / - - - h h h h h - / (4.7, 14.8, 6.2, 25.0, 23.3, 8.5, 8.5, 21.2, 13.5) 13.9
T242 * / 0.947 / PTRPTDKPL / ------/ (27.1, 52.2, 34.1, 1.4, 29.7, 38.1, 22.7, 12.1, 0.8) 24.2
T269 / 0.768 / GRVETGVLK / s s s s - - - - - / (0.0, 27.6, 0.9, 17.6, 0.9, 1.1, 17.2, 0.0, 30.4) 10.6
T287 / 0.547 / VNVTTEVKS / - - s s s s s s s / (13.2, 43.4, 10.1, 28.4, 9.1, 24.9, 1.3, 28.2, 27.1) 20.6
T432 * / 0.951 / DMRQTVAVG / s s - - s s s s s / (13.4, 42.1, 52.6, 25.7, 24.6, 0.4, 0.0, 8.8, 0.0) 18.6

° The position in the secondary structure of Ser and Thr residues and the corresponding solvent accessibility within the consensus sequence is in shadow.

* Residues showing the highest score.