Table S1List of up-regulatedgenes

Categorya / Signal Log Ratiob / ID / Product
AUT1
A / 2.8 / AO090023000965 / Nucleolar protein fibrillarin NOP77 (RRM superfamily)
B / 2.6 / AO090026000794 / Predicted component of NuA3 histone acetyltransferase complex
V / 3.8 / AO090005000498 / Predicted protein
T / 2.2 / AO090011000286 / 1-aminocyclopropane-1-carboxylate synthase, and related proteins
O / 2.4 / AO090003000180 / Cytochrome oxidase assembly factor COX15
O / 2.1 / AO090011000764 / Mitochondrial chaperonin, Cpn60 Hsp60p
O / 4 / AO090012000667 / Predicted protein
O / 3.1 / AO090023000260 / Thioredoxin reductase
O C / 2.1 / AO090023000863 / Holocytochrome c synthase heme-lyase
C / 2.3 / AO090001000555 / Branched chain alpha-keto acid dehydrogenase complex, alpha subunit
C / 3.6 / AO090003000831 / Fumarate reductase, flavoprotein subunit
C / 2 / AO090003001006 / Proteins containing the FAD binding domain
C / 2.4 / AO090003001007 / Glycolate oxidase
C / 2.8 / AO090003001008 / Dihydrolipoamide transacylase (alpha-keto acid dehydrogenase E2 subunit)
C / 5 / AO090005000495 / Predicted acyl-CoA transferases/carnitine dehydratase
C / 3.7 / AO090005000588 / Acetyl-CoA hydrolase
C / 3.9 / AO090005001312 / Predicted acyl-CoA transferases/carnitine dehydratase
C / 3 / AO090009000568 / Citrate synthase
C / 2.9 / AO090010000579 / Glyoxylate/hydroxypyruvate reductase (D-isomer-specific 2-hydroxy acid dehydrogenase superfamily)
C / 2.1 / AO090011000202 / Globins and related hemoproteins
C / 2.7 / AO090023000140 / Sulfide:quinone oxidoreductase/flavo-binding protein
C / 2.2 / AO090102000627 / Citrate synthase
C H / 2.6 / AO090011000149 / NADH-cytochrome b-5 reductase
C R / 2.7 / AO090011000154 / Predicted protein

Table S1 List of up-regulated genes (continued 1)

C R / 2 / AO090023000592 / Zinc-binding oxidoreductase
G / 2.9 / AO090003000211 / Fumarylacetoacetase
G / 2.8 / AO090005000189 / Predicted protein
G / 2.4 / AO090011000153 / Predicted protein
G / 2.2 / AO090011000715 / Endoglucanase
G / 6.1 / AO090103000218 / Chitinase
G / 3.8 / AO090701000639 / Alpha-glucosidases, family 31 of glycosyl hydrolases
G E P R / 2.7 / AO090011000572 / Permeases of the major facilitator superfamily
E / 2.1 / AO090003000208 / 4-hydroxyphenylpyruvate dioxygenase
E / 2 / AO090003000210 / Homogentisate 1,2-dioxygenase
E / 2 / AO090005001081 / Amino acid transporters
E / 2.4 / AO090010000699 / Amino acid transporters
E / 2 / AO090012000899 / Aspartate aminotransferase/Glutamic oxaloacetic transaminase AAT2/GOT1
E / 3.3 / AO090020000444 / Aromatic amino acid aminotransferase and related proteins
E / 3.4 / AO090023000923 / Glutamate/leucine/phenylalanine/valine dehydrogenases
E / 2.4 / AO090102000173 / Glycine/D-amino acid oxidases (deaminating)
E I / 2.3 / AO090020000493 / Isovaleryl-CoA dehydrogenase
E Q / 2.1 / AO090009000580 / N-methylhydantoinase A/acetone carboxylase, beta subunit
E Q / 2.2 / AO090026000066 / N-methylhydantoinase A/acetone carboxylase, beta subunit
F / 2.1 / AO090010000345 / Predicted protein
F / 2.1 / AO090011000062 / Adenine deaminase/adenosine deaminase
F / 2 / AO090012001004 / Adenylate kinase
H / 2.2 / AO090001000559 / Ubiquinone biosynthesis methyltransferase COQ5
H / 2.7 / AO090011000155 / Demethylmenaquinone methyltransferase
H / 2.9 / AO090012000998 / Coproporphyrinogen III oxidase CPO/HEM13
I / 3.2 / AO090001000224 / Fatty acid desaturase
I / 2.3 / AO090001000295 / Carnitine O-acyltransferase CPT2/YAT1

Table S1 List of up-regulated genes (continued 2)

I / 2.6 / AO090003000250 / Soluble epoxide hydrolase
I / 3.2 / AO090005000456 / Fatty acid desaturase
I / 3.5 / AO090005000494 / Acyl-CoA dehydrogenases
I / 3.3 / AO090005001107 / Sterol C5 desaturase
I / 2.6 / AO090005001117 / Sphingolipid fatty acid hydroxylase
I / 4.2 / AO090010000667 / C-4 sterol methyl oxidase
I / 2 / AO090026000404 / Carnitine O-acyltransferase CRAT
I / 4 / AO090102000339 / Fatty acid desaturase
I / 2.5 / AO090701000359 / Myo-inositol-1-phosphate synthase
I Q R / 3.1 / AO090010000522 / Predicted protein
P / 2.3 / AO090012000034 / Predicted flavoprotein involved in K+ transport
P / 2.6 / AO090012000725 / Alkaline phosphatase
P / 3.4 / AO090012000901 / Na+/Pi symporter
P / 2.9 / AO090103000329 / Catalase (peroxidase I)
Q / 5 / AO090003000205 / Cytochrome P450
Q / 2.2 / AO090011000015 / Polyketide synthase modules and related proteins
Q / 2.8 / AO090011000017 / Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily
Q / 4.3 / AO090011000415 / Cytochrome P450
Q / 2.9 / AO090011000926 / Lysine/ornithine N-monooxygenase
Q / 5.7 / AO090020000380 / Non-ribosomal peptide synthetase modules and related proteins
Q / 2.7 / AO090166000070 / Cytochrome P450
Q / 3.3 / AO090701000490 / Copper amine oxidase
Q / 2.6 / AO090701000508 / Alcohol dehydrogenase, class III
AUT2
J F / 2.1 / AO090102000054 / Cytosine/adenosine deaminases
A / 2 / AO090103000144 / Predicted protein

Table S1 List of up-regulated genes (continued 3)

K L / 3.1 / AO090005000258 / Helicase-like transcription factor HLTF/DNA helicase RAD5, DEAD-box superfamily
T / 2.2 / AO090038000122 / Acetylcholinesterase/Butyrylcholinesterase
M / 3.4 / AO090011000042 / Predicted protein
O / 2.1 / AO090038000288 / Chaperone HSP104 and related ATP-dependent Clp proteases
G / 4.5 / AO090001000282 / Monocarboxylate transporter
G E P R / 4.5 / AO090023000399 / Permeases of the major facilitator superfamily
F / 2.3 / AO090011000504 / Dihydroorotase and related enzymes
Q / 3.3 / AO090701000831 / Polyketide synthase modules and related proteins
AUT3
J / 2 / AO090005000706 / Seryl-tRNA synthetase
K / 2.1 / AO090020000119 / RNA polymerase II transcription mediator
B / 2.2 / AO090005000416 / chromatin remodeling factor subunit and related transcription factors
B / 3.1 / AO090026000794 / Predicted component of NuA3 histone acetyltransferase complex
D / 2.2 / AO090012000714 / Protein involved in sister chromatid separation and/or segregation
D R / 4.7 / AO090003001276 / Predicted protein
T / 4.4 / AO090138000024 / Signal transduction histidine kinase
T I / 2.1 / AO090023000728 / Sterol reductase/lamin B receptor
M / 2.4 / AO090005001490 / UDP-glucose 4-epimerase
M / 2.3 / AO090010000463 / UDP-glucose 4-epimerase/UDP-sulfoquinovose synthase
M G / 3.9 / AO090001000164 / Predicted protein
U O / 2.5 / AO090005000630 / Endoplasmic reticulum membrane-associated oxidoreductin involved in disulfide bond formation
O / 2.8 / AO090003000180 / Cytochrome oxidase assembly factor COX15
O / 2.1 / AO090005001209 / Chaperone HSP104 and related ATP-dependent Clp proteases
O / 2 / AO090011000638 / Molecular chaperones mortalin/PBP74/GRP75, HSP70 superfamily
O / 2.4 / AO090011000764 / Mitochondrial chaperonin, Cpn60/Hsp60p
O / 5.3 / AO090012000667 / Predicted protein

Table S1 List of up-regulated genes (continued 4)

O / 2.4 / AO090023000570 / Glutathione S-transferase
O / 3.7 / AO090038000288 / Chaperone HSP104 and related ATP-dependent Clp proteases
O / 2.8 / AO090701000063 / Armadillo/beta-catenin-like repeat-containing protein
C / 2.2 / AO090001000358 / NADH-dehydrogenase (ubiquinone)
C / 4.4 / AO090003000831 / Fumarate reductase, flavoprotein subunit
C / 2.7 / AO090003001006 / Proteins containing the FAD binding domain
C / 5.2 / AO090003001007 / Glycolate oxidase
C / 2.7 / AO090003001215 / NADP/FAD dependent oxidoreductase
C / 3.5 / AO090005000588 / Acetyl-CoA hydrolase
C / 2.3 / AO090005000592 / Fumarate reductase, flavoprotein subunit
C / 2 / AO090010000579 / Glyoxylate/hydroxypyruvate reductase (D-isomer-specific 2-hydroxy acid dehydrogenase superfamily)
C / 2.8 / AO090011000202 / Globins and related hemoproteins
C / 4.5 / AO090012000624 / NAD(P)H-nitrite reductase
C / 3.6 / AO090012000675 / NADH:flavin oxidoreductases, Old Yellow Enzyme family
C / 2.6 / AO090023000140 / Sulfide:quinone oxidoreductase flavo-binding protein
C / 3 / AO090023000871 / Glycolate oxidase
C / 2.4 / AO090102000252 / Glycolate oxidase
C / 2.2 / AO090102000627 / Citrate synthase
C H / 2.2 / AO090009000294 / Monooxygenase involved in coenzyme Q (ubiquinone) biosynthesis
C H / 3.3 / AO090011000149 / NADH-cytochrome b-5 reductase
C R / 2.8 / AO090005001535 / NADH:flavin oxidoreductase/12-oxophytodienoate reductase
C R / 2.1 / AO090011000154 / Predicted protein
C R / 2.1 / AO090011000419 / NADPH:quinone reductase and related Zn-dependent oxidoreductases
C R / 2.5 / AO090023000443 / NADH:flavin oxidoreductase/12-oxophytodienoate reductase
C R / 2.9 / AO090023000592 / Zinc-binding oxidoreductase
G / 3.1 / AO090003001514 / Predicted protein
G / 2.4 / AO090005000582 / Predicted protein

Table S1 List of up-regulated genes (continued 5)

G / 2 / AO090010000444 / Pyrophosphate-dependent phosphofructo-1-kinase
G / 3.8 / AO090011000203 / Aquaporin (major intrinsic protein family)
G / 3 / AO090011000715 / Endoglucanase
G / 2 / AO090012000711 / Phosphoketolase
G / 2.4 / AO090020000035 / Trehalose-6-phosphate synthase component TPS1 and related subunits
G / 2.5 / AO090103000020 / Glucosamine-6-phosphate isomerase
G / 2.2 / AO090103000023 / N-acetyl-glucosamine-6-phosphate deacetylase
G / 4.9 / AO090103000218 / Chitinase
G / 2 / AO090701000841 / Beta-glucosidase-related glycosidases
G E P R / 2.4 / AO090011000572 / Permeases of the major facilitator superfamily
E / 2 / AO090005001081 / Amino acid transporters
E / 2.3 / AO090010000699 / Amino acid transporters
E / 2 / AO090023000646 / Amino acid transporters
E / 4 / AO090023000923 / Glutamate/leucine/phenylalanine/valine dehydrogenases
E / 3 / AO090102000173 / Gycine/D-amino acid oxidases (deaminating)
E / 3.2 / AO090166000026 / Amino acid transporters
E / 2.1 / AO090701000621 / Amino acid transporters
E H / 2 / AO090023000516 / 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes
E H / 2.9 / AO090166000076 / Thiamine pyrophosphate-requiring enzyme
F / 3.9 / AO090003000332 / Predicted protein
F / 2.1 / AO090010000345 / Predicted protein
H / 3.1 / AO090012000998 / Coproporphyrinogen III oxidase CPO/HEM13
H / 5.3 / AO090020000109 / Protein involved in ubiquinone biosynthesis
I / 3.7 / AO090001000224 / Fatty acid desaturase
I / 2 / AO090003000250 / Soluble epoxide hydrolase
I / 3.4 / AO090005000456 / Fatty acid desaturase
I / 2.3 / AO090005000995 / Sphingolipid hydroxylase

Table S1 List of up-regulated genes (continued 6)

I / 4.1 / AO090005001107 / Sterol C5 desaturase
I / 3 / AO090005001117 / Sphingolipid fatty acid hydroxylase
I / 5.3 / AO090010000667 / C-4 sterol methyl oxidase
I / 2.8 / AO090023000893 / Fatty acid desaturase
I / 2.5 / AO090023000899 / Acyl-CoA synthetase
I / 2.5 / AO090026000404 / Carnitine O-acyltransferase CRAT
I / 5.1 / AO090102000339 / Fatty acid desaturase
I / 2.3 / AO090103000138 / Sterol C5 desaturase
I / 2.3 / AO090206000001 / C-4 sterol methyl oxidase
I / 2.1 / AO090701000359 / Myo-inositol-1-phosphate synthase
I / 2.6 / AO090701000685 / Squalene monooxygenase
I R / 3.7 / AO090023000624 / SAM-dependent methyltransferases
P / 2.4 / AO090003001096 / Predicted carbonic anhydrase involved in protection against oxidative damage
P / 2 / AO090005000227 / Na+/Pi symporter
P / 2.8 / AO090010000641 / Na+/Pi symporter
P / 2.9 / AO090012000725 / Alkaline phosphatase
P / 3.4 / AO090012000901 / Na+/Pi symporter
P / 3.9 / AO090103000329 / Catalase (peroxidase I)
Q / 5.2 / AO090003000205 / Cytochrome P450
Q / 5.3 / AO090011000415 / Cytochrome P450
Q / 2.5 / AO090011000926 / Lysine/ornithine N-monooxygenase
Q / 4.5 / AO090020000380 / Non-ribosomal peptide synthetase modules and related proteins
Q / 2 / AO090026000001 / Polyketide synthase modules and related proteins
Q / 2 / AO090038000303 / Pleiotropic drug resistance proteins (PDR1-15), ABC superfamily
Q / 2 / AO090102000589 / Multicopper oxidases
Q / 3.3 / AO090166000070 / Cytochrome P450
Q / 2.8 / AO090701000490 / Copper amine oxidase

aFunctional categories were designated by cluster of orthologous group (COG) according to gene list of DOGAN ( The genes classified into only R, S, and X are not displayed.

bThe value of log2 (the signal intensity in the AUT strains/ the signal intensity in the control strain) is indicated.