Syed Habib Bokhari
Office: 0512501223
FAX: 0514442805
Email:
DOB: 01-3-1973
EDUCATION
Jan, 1999-Dec, 2002 Univ. of Glasgow Microbiology & Immunology Ph.D.
Jan, 1995-July, 1997 Q.A.U, Pakistan Biotechnology, M. Phil.
RESEARCH SPECIALIZATION
Infectious Diseases, Glycoengineering, Biosensors, Bioinformatics
Professional EXPERIENCE
2010 to date Associate Professor
Department of Biosciences
CIIT, Islamabad
Feb 2003-2010 Assistant Professor,
Department of Biosciences
CIIT, Islamabad
2008-2008 Head,
Department of Biosciences
CIIT, Islamabad
2007-present: Affiliate faculty
Bioinformatics and Computational Biology
College of Science
George Mason University, Manassas, Virginia
2009-2010 Post Doc
Department of Microbial Pathogenesis
London School of Hygiene and Tropical Medicine
2005-2006: Visiting Scientist
Department of Environmental Sciences and Policy
George Mason University, Fairfax, Virginia 22030
2001- 2002: Demonstrator (Microbiology and Molecular Biology)
Institute of Biomedical and Life Sciences
Univ. of Glasgow, Glasgow
Sep, 1996- Jan, 2003: Lecturer
Post Graduate Botany Department
Govt. S. E. College, Bahawalpur
Awards/Scholarships/ Memberships:
1. Recipient of Commonwealth scholarship for Ph.D. (1999-2002)
2. Short-listed for Fulbright scholarship (1998-9: Did not pursue),
3. France scholarship for Ph.D. (1998-99: Did not pursue)
4. Selected for cultural scholarship for Ph.D. (1998-99: Did not pursue)
5. Awarded Roll of Honor for standing first in B.Sc. in Botany, Zoology, Chemistry group
6. President Talent Scholarships at B.Sc. and M.Sc. Levels
7. Infaq Foundation Scholarship (HEC) at M.phil level
8. Member General Council, University of Glasgow
9. Member Zoological Society of Pakistan
10. Member HEC curriculum committee for Bioinformatics
11. Expert Member of HEC Project Reviewer’s committee
12. Editor of the journal of Integrative Computational Biosciences (JICB)
13. Member Society for General Microbiology, UK
14. Member American Nanosociety
15. Member Board of studies Department of Microbiology, QAU, Islamabad
16. Member Board of studies Department of Biochemistry, QAU, Islamabad
Research Articles: (Total Impact Factor 46.386)
1. H. Bokhari,1 F. Said1, M.A. Syed1, A. Hussain,2 Y. F. Kazi, 2 Teemu Kallonenc, Qiushui Hec, Audrey J. Kingd K. Heuvelman3 and F. R. Mooi3 . 2011. Molecular typing of Bordetella parapertussis isolates circulating in Pakistan (Accepted: FEMS Immunology & Medical Microbiology) (IF= 2.35)
2. Bokhari Habib1*, Zafar Sadia1 and Bilal Iram1. 2011. BORDETELLA AUTOTRANSPORTER PROTEIN C IS AN ADHESION FACTOR FOR BORDETELLA PERTUSSIS. (Accepted: Journal of basicMicrobiology ( IF= 1.39)
3. H. Bokhari,F. Said, M.A. Syed, A. Hussain, Y. F. Kazi, K. Heuvelman A. king, He Q and F. R. Mooi. 2011. Whooping cough in Pakistan: Bordetella pertussis vs Bordetella parapertussis in 2005 – 2009 (Available online: Scandinavian journal of infectious diseases ( IF= 1.72)
4. M. A. Syed1*, A. S. Bhatti2, R. Guduru3, C. Z. Li3 and S. H. A. Bokhari . 2011. Use of SPR biosensor for the study of proteolytic action of a serine protease enzyme (Accepted: American Journal of Biomedical Sciences)
5. H. Bokhari, H. Bilal, M. Anwer & Patrick Gillevet. 2011. Evidences of lateral gene transfer between Archaea and pathogenic bacterial genomes (Bioinformation, 6(8): 293-296); ( IF= 1.43)
6. Asif Raza, Hira Shareef, Hira Salim, Rashid Khushal, Habib Bokhari 2011. Selection of predicted siRNA as potential antiviral therapeutic agent against influenza virus ( Bioinformation, 6(9): 340-343; ( IF= 1.43)
7. Sadia Zafar, Arshan Nasir, Habib Bokhari. 2011. Computational analysis reveals abundance of potential glycoproteins in Archaea, Bacteria and Eukarya. Bioinformation, 6(9): 352-355; ( IF= 1.43) INDIA
8. Mojtaba Noofeli, Habib Bokhari, Paul Blackburn, Mark Roberts, John Coote & Roger Parton. 2011. BapC autotransporter protein is a virulence determinant of Bordetella pertussis. Microbial Pathogenesis: 51(3):169-77. ( IF= 2.34)
9. Syed Tabish, Abbas Raza, Arshan Nasir, Sadia Zafar and Habib Bokhari. 2011. Analysis of glycosylation patterns and glycosyltransferases in Bacteria and Archaea (Bioinformation, 6(5): 191-195; (IF= 1.43)
10. Idrees, M., Mussarat, U., Badshah, Y., Qadir, M and Bokhari, H*. 2011. Prevalence of antimicrobial resistance and integrons in uropathogenic Escherichia coli, from Punjab, Pakistan : Brazilian Journal of Microbiology 42: 462-466 ( IF= 0.62)
11. Maleeha Azam, Rob W.J.Collin,Ayesha Malik, Muhammad I. Khan, Syed Tahir A. Shah1 Aftab A. Shah, Alamdar Hussain, Ahmed Sadeque, Kentar Arimadyo Muhammad Ajmal, Ayesha Azam Nadeem Qureshi, Habib Bokhari, Tim M. Strom, Frans P. M. Cremers, Raheel Qamar, Anneke I. den Hollander. 2011. Identification of novel mutations in Pakistani families with autosomal recessive retinitis pigmentosa (In Press/Accepted. Archives of Ophthalmology (IF= 3.86)
12. Syed M. A and Bukhari S. H. A*. 2011. Gold nanoparticle based microbial detection and identification. J. Biomed. Nanotechnol. Vol. 7, 1–9, 2011 (IF=2.626)
13. Muhammad Idrees1, Muhammad Ali Shah1 Raheel Qamar1 and Habib Bokhari1*. 2011. Antimicrobial Resistant Escherichia coli Strains Isolated from Food Animals in Pakistan. Pakistan Journal of Zoology. 43(2), 303-310, (IF= 0.15)
14. H. Bokhari*, C. Smith, K. Veerendra, J. Sivaraman, M. Sikaroodi, P. Gillevet. 2010. Novel Fluorescent Proteins From Hydnophora Rigida Possess Cyano emission. Biochemical and Biophysical Research Communications 396(3):631-636. (IF= 2.59)
15. Amna Salman, Atefeh Taherian Fard Arshan Nasir & Habib Bokhari. 2010. Comparative analysis of organophosphate degrading enzymes from diverse species. Bioinformation 5(2): 67-72 ( IF= 1.43)
16. Muhammad Ali Syed, Umair Manzoor, Ismat Shah and Habib Ali Bukhari*. 2010. .Antibacterial effects of Tungsten nanoparticles on the Escherichia coli strains isolated from catheterized urinary tract infection (UTI) cases and Staphylococcus aureus. New Microbiologica., 33(4):329-35. ( IF= 0.96)
17. Idrees, M., Mussarat, U., M., Badshah, Y., Qamar, R. and Bokhari, H*. 2010. Virulence factors profile of drug resistant Escherichia coli isolated from urinary tract infections, in Punjab, Pakistan (European Journal of Clinical Microbiology & Infectious Diseases, 29(12):1533-7. IF= 2.65)
18. Muhammad Ali Syed, Syed Habib Ali Bukhari*. 2010. Adult and adolescent pertussis should not be underestimated!. Pak J Med Sci. Vol. 26 No. 1, 44-45. ( IF= 0.2)
19. Taimoor Hashmi1, Shakil Khan1, Valeed1, Habib Bokhari*1 2010. In silico identification of vaccine candidates against enteric pathogens by comparative genome sequence. (Asian Pacific Journal of Molecular Biology and Biotechnology, 18(3): 327-331
20. Hasan Bilal Mirza, Maryam Anwar & Habib Bokhari. 2010. In silico identification of potential horizontal gene transfer events between Archaea and pathogenic Bacteria. Journal of Bioinformatics and Sequence Analysis (JBSA). 2(3), 36-41, 2010
21. MuhammadAjmal, WaqasAhmed, AhmedSadeque, SyedaHafizaBenishAli, SyedHabibBokhari, NuzhatAhmed and RaheelQamar. 2010. Identification of a recurrent insertion mutation in the LDLR gene in a Pakistani family with autosomal dominant hypercholesterolemia. Molecular Biology Reports. 37(8); 3869-3875. (IF= 2.038)
22. Muhammad Ali Syed1, Shaista Babar2, A. S. Bhatti2, & Habib A. Bokhari*. 2009. Antibacterial effects of silver nanoparticles on the bacterial strains isolated from catheterized urinary tract infection cases. Journal of Biomedical Nanotechnology., 5: 209-214 ( IF= 2.626).
23. Muhammad Ali Syed, Fahad Said, S. Habib Ali Bukhari*. 2009. Seroepidemiology of Bordetella pertussis infections in the twin cities of Pakistan.
North Am J Med Sci. 1: 353-355.
24. Atefeh Taherian Fard 1, Amna Salman1, Bahram Kazemi 2 and Habib Bokhar*. 2009. In silico comparative genome analysis of malaria parasite Plasmodium falciparum and Plasmodium vivax chromosome 4. Parasitology Research., 104 (6): 1361 (IF= 1.81)
25. Maleeha Azam1,2, Muhammad Imran Khan1, Alamdar Hussain1, Syed Tahir Abbas Shah1, Muhammad Shakil Khan1,3, Ahmed Sadeque1, Habib Bokhari1, Rob W.J. Collin2,4, Maria M. van Genderen5, A.I. den Hollander2,4, Frans P. M. Cremers2,4, Raheel Qamar1, 3. 2009. A homozygous p.Glu150Lys mutation in the opsin gene of two Pakistani families with autosomal recessive retinitis pigmentosa: Molecular Vision, 3;15:2526-34. ( IF= 2.33).
26. Siddiqa, A., Niazi, M., Mustafa, F., Bokhari, H., Hussain, A., Akram, N., Shaheen, S., Ahmed, F. and Iqbal, S. 2009. A new hybrid agent-based modeling & simulation decision support system for breast cancer data analysis. In: Proc Information and Communication Technologies, pp. 134-139. ICICT '09 International Conference on Aug. 15-16. (ISI-Indexed, Non-IF).
27. S. HABIB BOKHARI* & P. BLACKBURN. 2008. Purification and protective efficacy of re-natured C-terminal domain (P.30) of pertactin autotransporter protein of B. pertussis. Pak. J. Bot., 40(2):825-832 ( IF= 0.947)
28. S. HABIB BOKHARI* & P. BLACKBURN. 2008. Pertactin processing and secretion in protease(s) deficient strains of Escherichia coli suggestive of the possible role of proteases in folding of autotransporter proteins. Pak. J. Bot., 40(2):815-824( IF= 0.947)
29. Shahid Mahmood Baig, Ayesha Azhar, Hammad Hassan, Jamshaid Mahmood Baig, Ayesha Kiyani, Uzma Hameed, Fazli Rabbi, Habib Bokhari, Muhammad Aslam, Mohammad Amin Ud Din, Shehla Anjum Baig, Khalid Hassan, Javed Anwar Qureshi and Tariq Zaman. 2006. Spectrum of beta-thalassemia mutations in various regions of Punjab and Islamabad, Pakistan: establishment of prenatal diagnosis. Haematologica/The hematology journal. 91(1), 3-5. (IF=6.532)
30. S. M. Baig, F. Rabbi, U. Hameed, J. A. Qureshi, Z. Mahmood, S.H. Bokhari, A. Kiani, H, Hassan, J.M. Baig, A. Azhar, T. Zaman. 2005. Molecular characterization of mutations causing β-thalassemia in Faisalabad Pakistan using the amplification refractory mutation system (ARMS-PCR). Ind. J. Hum. Gen.11(2), 80-83 (Pubmed Indexed).
Manuscripts Submitted & in Preparation:
1 Syed M. A. and Bukhari S. H. A. 2011. Serosurveillance of Pertussis toxin IgG in infants and children of the twin cities of Pakistan (Islamabad and Rawalpindi). (Minor Revision: J. col. Phy. Surg). ( IF= 0.55)
2
3 Ashfaq Mahmood1, Muhammad Ismail, Muhammad Athar, Rashid Khushal, Mehmood Qadir2, Riaz Ahmed, Muhammad Idrees1, Muhammad Rauf, Habib Bokhari1* .Antimicrobial efficacy of metal-barbiturate conjugates against pathogenic strains of Escherichia coli and Staphylococcus aureus. (Revision Submitted: Letters in Drug Design & Discovery); (IF=0.805).
4 Bokhari H, Shah MA, Asad S, Fariha S and Wren BW. Analysis of Diarrheagenic Escherichia coli and V. cholerae subsequent to the 2010 Floods in Pakistan. (Submitted FEMS Microbiology Ecology (IF= 3.9)
5 Sadaf Afzal, Shams ul Islam, Bilal Ghori, M. Saleet Jafri, Habib Bokhari*. Mathematical model for disinfection of drinking water from Local pathotypes of Escherichia coli (Submitted International journal of Biomathematics (IF= 1.61)
6 Mughal. A. A, Kazi Y., Bokhari S. H. and Syed M. A. Pertussis resurgence in Khairpur Pakistan among vaccinated children. (Submitted: J. Public Health). (IF= 1.23)
7 Muhammad Ali Syed1, Fahad Said1, Amjad Mughal2, Yasmeen Kazi2 and Habib Bokhari1*. Analysis of Quinolone and Sulfonamide resistance in Bordetella parapertussis isolates in Pakistan (Submitted: J. Medical Microbiology.) (IF= 2.65)
8 Pervez S., Syed M. A, Azam A., Nawaz E., Akhter S., Bukhari S. H. A and Ali Q. Isolation and characterization of Mycobacterium tuberculosis and Mycobacterium bovis in clinical isolates from patients of pulmonary tuberculosis in Rawalpindi and Islamabad. (Submitted: Pakistan Journal of Zoology);(IF= 0.15)
9 A. Rauf1* H. McNab2 H. Bokahari & A. M. Qureshi3. SYNTHESIS AND UREASE INHIBITION OF N-ARYL SUBSTITUTED 3-AMINOMETHYLENECHROMAN-2,4-DIONES AND THIER ANTI-INFLAMMATORY BURST ACTIVITY STUDIES ON HUMAN RESPIRATORY NEUTROPHILS (Submitted: Journal of Medicinal Chemistry);( IF=1.03)
10 Sadia Zafar, Syed Tarique Moin, Zaheer Ul-Haq & Habib Bokhari. In silico template-based structural modeling and molecular dynamics simulation of two bacterial Oligosaccharyl Transferases (Submitted: Molecular graphics and Modeling);(IF=2.033)
11 Fariha S,.Saba A, Akram M, Naila Batool, Mehwish I, Shah MA, Wren BW & Bokhari H. Analysis of Diarrhea associated Escherichia coli pathotypes following the 2010 Floods in Pakistan (Submitted: European Journal of Clinical Microbiology & Infectious Diseases, (IF= 2.65)
12 Habib Bokhari, Rebecca Langdon, Dennis Linton and Brendan Wren. Oligosaccharyly transferase PglB of Campylobacter jejuni is a glycoprotein. (In preparation)
13 Ahmed F, Iqbal S, Shaheen S, Siddiqa A, Akram N, Shan M.K.N, Niazi M, Mustafa F and Bokhari H. Epidemiological Study of Breast Cancer in Pakistan (In preparation)
14 Bokhari H*, Akram M, Ehsan S, Ali S Detection of non-tuberculous mycobacteria and members of mycobacterium tuberculosis complex by culture and molecular methods (In preparation).
15 Bibi.Z ,Hayat.R and Bokhari. H. EpiCIIT’- a customized tool for visualization and analysis of Epidemiological data. methods (In preparation).
16 Saba A, Shah MA, Wren BW & Bokhari H. Antibiotic resistance profile and detection of qnr genes among Diarrheogenic Bacterial Pathogens in Pakistan. (In preparation)
17 Habib Bokhari , Mojtaba Noofeli , Blackburn P. Cloning, expression and purification of Bap-C antigen of Bordetella pertussis in E. coli and its characterization (In preparation)
18 Muhammad Idrees and Habib Bokhari. Methyl parathion degrading bacteria isolated from agricultural areas of Pakistan (In preparation)
19 Saba Asad 1, Madeeha Hussain1, Ayesha Siddequa1, Habib Bokhari1§. In silico approaches for the identification & differentiation of Mycobacterium species (In preparation)
20 Muhammad Idrees, Muhammad Akram, Muhammad Ajmal, Raheel Qamar and Habib Bokhari. Paraoxonase-1 contribution to familial hypercholesterolemia in Pakistani families (In preparation).
Papers & Posters Presented and Published at Refereed International Conferences:
Bokhari, S. H., Blackburn, P., Coote, J., Roberts, M. and Parton, R. 2006.BapC, a newly identified member of the Bordetella Pertussis autotransporter family & its pathogenic potential. Proceedings of Fifth International Biennial Conference of Pakistan Society for Microbiology, “Molecular Mechanism of Host-Pathogen Interactions”. Karachi, Pakistan
Bokhari, S. H., Blackburn, P., Coote, J., Roberts, M. and Parton, R. 2003. The role of Bordetella pertussis Bap-5 protein in serum resistance and colonization in vitro and in vivo. First international and national symposium on Biotechnology. Jamshoro, Pakistan.
Bokhari, S. H., Blackburn, P., Coote, J., Roberts, M. and Parton, R. 2002. Bap-5, a newly identified member of the Bordetella Pertussis autotransporter family. Poster 11. American Society for Microbiology, Seventh International Symposium on Pertussis. Hinxton, United Kingdom.
Baig, S. M., Zaman, T., Hameed, A., Rabbi, F., Bukhari, S.H. et al. 2004.Molecular characterization of mutations causing β-thalassemia in Pakistan using amplification refractory mutation system (ARMS) and allele specific oligonucleotide (ASO) hybridization. HGVS Scientific and Annual General Meeting. Toronto, Canada.
Habib & Bokhari; Raheel Qamar, Muhammad Idrees, Yasmin Badshah & Uzma Mussarat. 2007. The prevalence of integrons among Escherichia coli isolated from different sources in Pakistan and associated drug resistance patterns. II International onference on Environmental, Industrial and Applied Microbiology; November–1 December, Seville, Spain
Habib & Bokhari; Umair Manzoor, Muhammad Ali, Asad Razzaq & Ismat Shah. 2007. Antibacterial effect of Tungsten nanoparticles on the E. coli strains isolated from catheterized urinary tract infection (UTI) cases and Staphylococcus aureus. II International Conference on Environmental, Industrial and Applied Microbiology. November–1 December, Seville, Spain