Supplementary Tables S1 - S12 Comparison of CYP1A2 Haplotypes Estimated from Five Different

Supplementary tables S1 - S12 Comparison of CYP1A2 haplotypes estimated from five different haplotype inference methods

Tables (a) are haplotype counts (for the entire CYP1A2 gene) generated from five different approaches: ELB (Excoffier et al., 2003), Expectation-Maximization (EM) (Excoffier and Slatkin, 1995), fastPHASE (FP) (Stephens and Scheet, 2006) and two extensions of the Clark (1990) algorithm, Clark-ancestral and Clark-common. Each table shows counts from different datasets. Many of the tables continue over a number of pages. Tables (b) are pairwise Pearson correlation coefficients from linear regression analyses comparing haplotype counts.

Supplementary table S1a Pooled Ethiopian ascertainment and NIEHS populations dataset (World dataset)

CYP1A2 haplotype / ELB / EM / FP / Clark-ancestral / Clark-common /
AATCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 1 / 0 / 0 / 1 / 1
AATCTCGGAGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 0 / 1 / 1 / 0 / 0
CGGCTCGGAGACGGCTGGGGCCGAGCGGCCAGACCCCCCCTGCCCGCGGAGCCGTGTGAAC / 3 / 3 / 3 / 1 / 0
CGGCTCGGAGACGGCTGGGGCCGAGCGGCCAGATCCCCCCTGCCCGCGGAGCCGTGTCAAC / 0 / 0 / 0 / 2 / 0
CGGCTCGGAGACGGCTGGGGCCGGGCAGCCAGACCCCCCCTGCCCGTGGAGCCGTGTGAAC / 0 / 0 / 0 / 0 / 2
CGGCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTGCCCGCGGCGCCGTGTGAAC / 0 / 0 / 0 / 0 / 1
CGGCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTGCCCGTGGAGCCGTGTGAAC / 0 / 0 / 0 / 0 / 1
CGGCTCGGAGACGGCTGGGGCCGGGCGGCCAGACCCCCCCTGCCCGCCGAGCCGTGTGAAC / 1 / 1 / 1 / 0 / 1
CGGCTCGGAGACGGCTGGGGCCGGGCGGCCAGACCCCCCCTGCCCGCGGAGCCGTGTGAAC / 9 / 9 / 9 / 1 / 6
CGGCTCGGAGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGGAGCCGTGTCAAC / 0 / 0 / 0 / 10 / 0
CGGCTCGGAGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGGAGCCGTGTGAAC / 2 / 1 / 2 / 1 / 0
CGGCTCGGAGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGGCGCCGTGTGAAC / 0 / 1 / 0 / 0 / 0
CGGCTCGGAGACGGCTGGGGCCTGGCGGCCAGACCCCCCCTGCCCGCGAAGCCGTGTCAAC / 0 / 0 / 0 / 2 / 0
CGGCTCGGAGACGGCTGGGGCCTGGCGGCCAGACCCCCCCTGCCCGCGGAGCCGTGTCAAC / 2 / 2 / 2 / 0 / 2
CGGCTCGGAGACGGCTGGGGCCTGGCGGCCAGACCCCCCCTGCCCGCGGAGCCGTGTGAAC / 17 / 17 / 17 / 4 / 8
CGGCTCGGAGACGGCTGGGGCCTGGCGGCCAGACCCCCCCTGCCCGCGGAGCTGTGTGAAC / 1 / 1 / 1 / 0 / 1
CGGCTCGGAGACGGCTGGGGCCTGGCGGCCAGACCCCCCCTGCCCGCGGATCCGGGTGAAC / 0 / 0 / 0 / 0 / 1
CGGCTCGGAGACGGCTGGGGCCTGGCGGCCAGACCCCCCCTGCCCGCGGCGCCGTGTGAAC / 0 / 0 / 0 / 0 / 1
CGGCTCGGAGACGGCTGGGGCCTGGCGGCCAGACCCCCCCTGCCCGTGGAGCCGTGTGAAC / 0 / 0 / 0 / 0 / 5
CGGCTCGGAGACGGCTGGGGCCTGGCGGCCAGATCCCCCCTGCCCGCGGAGCCGTGTCAAC / 0 / 0 / 0 / 13 / 0
CGGTTCGGAGACGGCTGGGGCCGGGCGGCCAGACCCCCCCTGCCCGCGGAGCCGTGTGAAC / 2 / 2 / 2 / 0 / 0
CGGTTCGGAGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 0 / 0 / 0 / 0 / 2
CGGTTCGGAGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGGAGCCGTGTCAAC / 0 / 0 / 0 / 2 / 0
CGTCTCAGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTGCCCGTGAAGCCGTGTCAAC / 1 / 1 / 1 / 0 / 0
CGTCTCAGCGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTGCCCGTGAAGCCGTGTCAAC / 0 / 0 / 0 / 1 / 1
CGTCTCGAAGACGGCTGGGGCAGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 0 / 2 / 0 / 0 / 0
CGTCTCGAAGACGGCTGGGGCCGGGCGGCCAGACCCCCCCTGCCCGCGGAGCCGTGTGAAC / 0 / 1 / 0 / 0 / 0
CGTCTCGAAGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGACGCC-TGTCAAC / 0 / 2 / 0 / 0 / 0
CGTCTCGACGACGGCTGGGGCAGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 0 / 0 / 0 / 0 / 2
CGTCTCGACGACGGCTGGGGCCGGGCGGCCAGACCCCCCCTGCCCGCGAAGCCGTGTGAAC / 0 / 0 / 0 / 1 / 0
CGTCTCGACGACGGCTGGGGCCGGGCGGCCAGACCCCCCCTGCCCGCGGAGCCGTGTGAAC / 0 / 0 / 0 / 0 / 1
CGTCTCGACGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 13 / 8 / 13 / 12 / 7
CGTCTCGACGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGACGCCGTGTCAAC / 0 / 0 / 0 / 0 / 1
CGTCTCGGAGACAGCGGGGGCAGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 1 / 1 / 1 / 1 / 1
CGTCTCGGAGACGGCTCGGGCCGGGCAGCCAGATCCCCCCTGCCCGTGAAGCCGTGTGAAC / 0 / 0 / 0 / 1 / 0
CGTCTCGGAGACGGCTCGGGCCGGGCAGCCAGATCCCCCCTGCCCGTGGAGCCGTGTGAAC / 0 / 0 / 0 / 0 / 1
CGTCTCGGAGACGGCTCGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGGAGCCGTGTGAAC / 1 / 1 / 1 / 0 / 0
CGTCTCGGAGACGGCTGAGGCCGGGCGCCCAGATCTCCCCTGCCCGCGGAGCCGTGTGAAC / 1 / 1 / 1 / 0 / 1
CGTCTCGGAGACGGCTGAGGCCGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 0 / 1 / 1 / 0 / 1
CGTCTCGGAGACGGCTGAGGCCGGGCGGCCAGATCCCCCCTGCCCGCGACGCCGTGTCAAC / 0 / 1 / 1 / 0 / 1
CGTCTCGGAGACGGCTGGGGCAGGGCAGCCAGATCCCCCCTGCCCGTGAAGCCGTGTCAAC / 0 / 0 / 0 / 0 / 3
CGTCTCGGAGACGGCTGGGGCAGGGCAGCCAGATCCCCCCTGCCCGTGAATCCGGGTCAAC / 0 / 0 / 0 / 0 / 1
CGTCTCGGAGACGGCTGGGGCAGGGCAGCCAGATCCCCCCTGCCCGTGAATCCGTGTCAAC / 0 / 0 / 0 / 0 / 3
CGTCTCGGAGACGGCTGGGGCAGGGCAGCCAGATCCCCCCTGCCCGTGACGCCGTGTCAAC / 0 / 0 / 0 / 0 / 1
CGTCTCGGAGACGGCTGGGGCAGGGCGGCCAGATCCCCCCTGCCAGCGAAGCCGTGTCAAC / 3 / 3 / 3 / 3 / 3
CGTCTCGGAGACGGCTGGGGCAGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTATCAAC / 1 / 1 / 1 / 1 / 1
CGTCTCGGAGACGGCTGGGGCAGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 14 / 11 / 13 / 12 / 8
CGTCTCGGAGACGGCTGGGGCAGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTGAAC / 0 / 1 / 1 / 3 / 1
CGTCTCGGAGACGGCTGGGGCAGGGCGGCCAGATCCCCCCTGCCCGCGAATCCGGGTCAAC / 2 / 2 / 2 / 0 / 0
CGTCTCGGAGACGGCTGGGGCAGGGCGGCCAGATCCCCCCTGCCCGCGAATCCGTGTCAAC / 5 / 5 / 5 / 5 / 2
CGTCTCGGAGACGGCTGGGGCAGGGCGGCCAGATCCCCCCTGCCCGCGAATCCGTGTCAAT / 1 / 0 / 1 / 0 / 0
CGTCTCGGAGACGGCTGGGGCAGGGCGGCCAGATCCCCCCTGCCCGCGACGCCGTGTCAAC / 1 / 1 / 1 / 1 / 0
CGTCTCGGAGACGGCTGGGGCAGGGCGGCCAGATCCCCCCTGCCCGCGACTCCGTGTCAAT / 0 / 1 / 0 / 1 / 1
CGTCTCGGAGACGGCTGGGGCAGGGCGGCCAGATCCCCCCTGCCCGCGGAGCCGTGTGAAC / 0 / 0 / 0 / 0 / 1
CGTCTCGGAGACGGCTGGGGCAGGGCGGCCAGATCCCCCCTGCCCGTGAATCCGGGTCAAC / 0 / 0 / 0 / 1 / 0
CGTCTCGGAGACGGCTGGGGCAGGGCGGCCAGATCCCCCCTGCGCGCGAATCCGTGTCAAC / 1 / 1 / 1 / 1 / 1
CGTCTCGGAGACGGCTGGGGCAGGGCGGTCAGATCCCCCCTGCCAGCGAAGCCGTGTCAAC / 1 / 1 / 1 / 1 / 0
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGACCCCCCCTGCCCGCGAAGCCGTGTGAAC / 0 / 0 / 0 / 2 / 0
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGACCCCCCCTGCCCGTGAAGCCGTGTGAAC / 0 / 0 / 0 / 8 / 0
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCCGCCCGTGAAGCCGTGTCAAC / 1 / 1 / 1 / 1 / 1
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTACCCGCGAAGCCGTGTCAAC / 0 / 2 / 0 / 1 / 2
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTACCCGCGACGCCGTGTCAAC / 0 / 1 / 0 / 0 / 1
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTACCCGTGAAGCCGTGTCAAC / 0 / 0 / 0 / 0 / 2
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTGCCCATGAAGCCGTGTCAAC / 0 / 2 / 2 / 0 / 2
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 38 / 38 / 40 / 35 / 35
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCATC / 1 / 1 / 1 / 1 / 1
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTGCCCGCGAAGCCGTGTGAAC / 0 / 0 / 0 / 1 / 0
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTGCCCGCGACGCCGTGTCAAC / 3 / 1 / 2 / 2 / 2
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTGCCCGCGACGCC-TGTCAAC / 0 / 0 / 0 / 1 / 0
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTGCCCGCGGAGCCGTGTCAAC / 0 / 0 / 0 / 1 / 0
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTGCCCGCGGAGCCGTGTGAAC / 0 / 0 / 0 / 0 / 1
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTGCCCGTGAAGCCGTGTCAAC / 148 / 142 / 146 / 133 / 98
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTGCCCGTGAAGCCGTGTCGAC / 0 / 3 / 0 / 0 / 3
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTGCCCGTGAAGCCGTGTGAAC / 0 / 0 / 0 / 4 / 0
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTGCCCGTGAAGTCGTGTCAAC / 1 / 1 / 1 / 1 / 1
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTGCCCGTGACGCCGTGTCAAC / 0 / 0 / 0 / 0 / 7
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTGCCCGTGGAGCCGTGTGAAC / 0 / 0 / 0 / 0 / 3
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCGTGCCCGCGAAGCCGTGTGAAC / 0 / 0 / 0 / 1 / 0
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCGTGCCCGCGGAGCCGTGTGAAC / 0 / 0 / 0 / 0 / 1
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCGCTGCCCGTGAAGCCGTGTCAAC / 1 / 1 / 1 / 1 / 1
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGATCCCTCCTGCCCGTGAAGCCGTGTCAAC / 2 / 2 / 2 / 2 / 2
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGGTCCCCCCTGCCCGTGAAGCCGTGTGAAC / 0 / 0 / 0 / 1 / 0
CGTCTCGGAGACGGCTGGGGCCGGGCAGCCAGGTCCCCCCTGCCCGTGGAGCCGTGTGAAC / 0 / 0 / 0 / 0 / 1
CGTCTCGGAGACGGCTGGGGCCGGGCAGCTAGACCCCCCCTGCCCGCGAAGCCGTGTGAAC / 0 / 0 / 0 / 1 / 0
CGTCTCGGAGACGGCTGGGGCCGGGCAGCTAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 7 / 7 / 7 / 6 / 5
CGTCTCGGAGACGGCTGGGGCCGGGCGCCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 0 / 0 / 0 / 0 / 3
CGTCTCGGAGACGGCTGGGGCCGGGCGCCCAGATCCCCCCTGCCCGCGAAGCCGTGTGAAC / 0 / 0 / 1 / 0 / 0
CGTCTCGGAGACGGCTGGGGCCGGGCGCCCAGATCCCCCCTGCCCGCGACGCCGTGTGAAC / 1 / 1 / 0 / 0 / 1
CGTCTCGGAGACGGCTGGGGCCGGGCGCCCAGATCCCCCCTGCCCGCGGAGCCGTGTCAAC / 0 / 0 / 0 / 5 / 0
CGTCTCGGAGACGGCTGGGGCCGGGCGCCCAGATCCCCCCTGCCCGCGGAGCCGTGTGAAC / 6 / 6 / 6 / 1 / 2
CGTCTCGGAGACGGCTGGGGCCGGGCGCCCAGATCCCCCCTGCCCGTGGAGCCGTGAGAAC / 1 / 1 / 1 / 1 / 1
CGTCTCGGAGACGGCTGGGGCCGGGCGGCCAGACCCCCCCTGCCCGCGAAGCCGTGTGAAC / 0 / 0 / 0 / 1 / 0
CGTCTCGGAGACGGCTGGGGCCGGGCGGCCAGACCCCCCCTGCCCGCGGAGCCGTGTGAAC / 2 / 1 / 2 / 0 / 1
CGTCTCGGAGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTACCCGCGAAGCCGTGTCAAC / 0 / 0 / 0 / 0 / 1
CGTCTCGGAGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCACGAAGCCGTGTGAAC / 0 / 0 / 0 / 1 / 0
CGTCTCGGAGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCACGACGCCGTGTGAAC / 0 / 1 / 1 / 0 / 1
CGTCTCGGAGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 36 / 33 / 32 / 33 / 54
CGTCTCGGAGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTGAAC / 1 / 1 / 1 / 3 / 0
CGTCTCGGAGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGAAGCC-TGTCAAC / 2 / 2 / 2 / 2 / 2
CGTCTCGGAGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGACGCCGTGTCAAC / 3 / 1 / 2 / 3 / 2
CGTCTCGGAGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGACGCCGTGTGAAC / 1 / 0 / 0 / 0 / 0
CGTCTCGGAGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGACGCC-TGTCAAC / 18 / 15 / 17 / 17 / 0
CGTCTCGGAGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGACGCC-TGTCGAC / 0 / 1 / 1 / 0 / 0
CGTCTCGGAGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGGAGCCGTGTCAAC / 0 / 0 / 0 / 17 / 0
CGTCTCGGAGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGGAGCCGTGTGAAC / 15 / 14 / 14 / 4 / 10
CGTCTCGGAGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGGCGCCGTGTGAAC / 0 / 0 / 0 / 0 / 1
CGTCTCGGAGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGTGAAGCCGTGTCAAC / 1 / 1 / 1 / 1 / 0
CGTCTCGGAGACGGCTGGGGCCGGGCGGCCAGATCCCCCGTGCCCGCGGAGCCGTGTGAAC / 1 / 1 / 1 / 0 / 0
CGTCTCGGAGACGGCTGGGGCCGGGCGGCCAGATGCCCCCTGCCCGCGAAGCCGTGTCAAC / 0 / 1 / 1 / 1 / 1
CGTCTCGGAGACGGCTGGGGCCGGGCGGCCAGATGCCCCCTGCCCGCGGAGCCGTGTGAAC / 0 / 1 / 1 / 0 / 1
CGTCTCGGAGACGGCTGGGGCCGGGCGGCCAGGTCCCCCCTGCCCGCGGAGCCGTGTGAAC / 1 / 1 / 1 / 0 / 0
CGTCTCGGAGACGGTTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 0 / 1 / 1 / 0 / 0
CGTCTCGGAGAGGGCTGGGGCAGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 2 / 1 / 2 / 2 / 0
CGTCTCGGAGAGGGCTGGGGCAGGGCGGCCAGATCCCCCCTGCCCGCGACGCCGTGTCAAC / 0 / 1 / 0 / 0 / 0
CGTCTCGGAGGCGGCTGGGGCCGGGCAGCCAGATCCCCCCTGCCCGTGAAGCCGTGTCAAC / 1 / 1 / 1 / 0 / 0
CGTCTCGGATACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 0 / 0 / 0 / 0 / 2
CGTCTCGGATACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGACGCCGTGTCAAC / 4 / 4 / 4 / 4 / 2
CGTCTCGGCGACGGCTGAGGCCGGGCGGCCAGATCCCCCCTACCCGCGAAGCCGTGTCAAC / 0 / 1 / 1 / 0 / 1
CGTCTCGGCGACGGCTGAGGCCGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 4 / 1 / 1 / 4 / 1
CGTCTCGGCGACGGCTGAGGCCGGGCGGCCAGATCTCCCCTGCCCGCGAAGCCGTGTGAAC / 0 / 0 / 0 / 1 / 0
CGTCTCGGCGACGGCTGGGACCGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 1 / 1 / 1 / 1 / 1
CGTCTCGGCGACGGCTGGGGCCGGGCGGCCAGACCCCCCCTGCCCGCCAAGCCGTGTGAAC / 0 / 0 / 0 / 1 / 0
CGTCTCGGCGACGGCTGGGGCCGGGCGGCCAGACCCCCCCTGCCCGCGAAGCCGTGTGAAC / 0 / 0 / 0 / 13 / 0
CGTCTCGGCGACGGCTGGGGCCGGGCGGCCAGACCCCCCCTGCCCGCGAAGCTGTGTGAAC / 0 / 0 / 0 / 1 / 0
CGTCTCGGCGACGGCTGGGGCCGGGCGGCCAGACCCCCCCTGCCCGCGGAGCCGTGTGAAC / 0 / 0 / 0 / 0 / 2
CGTCTCGGCGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTACCCGCGAAGCCGTGTCAAC / 11 / 6 / 7 / 10 / 2
CGTCTCGGCGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTACCCGCGAAGCCGTGTCGAC / 0 / 1 / 1 / 0 / 1
CGTCTCGGCGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTACCCGCGACGCCGTGTCAAC / 0 / 0 / 2 / 0 / 1
CGTCTCGGCGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCACGAAGCCGTGTCAAC / 3 / 0 / 0 / 2 / 0
CGTCTCGGCGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTATCAAC / 3 / 3 / 3 / 3 / 3
CGTCTCGGCGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 254 / 280 / 267 / 230 / 255
CGTCTCGGCGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCGAC / 6 / 1 / 4 / 6 / 1
CGTCTCGGCGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTGAAC / 2 / 1 / 1 / 9 / 1
CGTCTCGGCGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGACGCCGTGTCAAC / 30 / 28 / 29 / 31 / 15
CGTCTCGGCGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGGAGCCGTGTCAAC / 0 / 0 / 0 / 1 / 0
CGTCTCGGCGACGGCTGGGGCCGGGCGGCCAGATGCCCCCTGCCCGCGAAGCCGTGTCAAC / 2 / 0 / 0 / 0 / 0
CGTCTCGGCGACGGCTGGGGCCGGGCGGCCAGATGCCCCCTGCCCGCGAAGCCGTGTGAAC / 0 / 0 / 0 / 1 / 0
CGTCTCGGCGACGGCTGGGGCCGGGCGGCCATATCCCCCCTACCCGCGAAGCCGTGTCAAC / 1 / 0 / 0 / 0 / 0
CGTCTCGGCGACGGCTGGGGCCGGGCGGCCATATCCCCCCTACCCGCGACGCCGTGTCAAC / 0 / 1 / 1 / 1 / 1
CGTCTCGGCGACGGCTGGGGCCGGGCGGCCCGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 2 / 2 / 2 / 2 / 2
CGTCTCGGCGACGGCTGGGGCCGGGCGGCTAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 0 / 0 / 0 / 0 / 2
CGTCTCGGCGACGGCTGGGGCCGGGCGGTCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 0 / 0 / 0 / 0 / 1
CGTCTCGGCGACGGCTGGGGCCGGTCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 1 / 1 / 1 / 1 / 1
CGTCTCGGCGACGGTTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 1 / 0 / 0 / 1 / 1
CGTCTCGGCGAGGGCTGGGGCAGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 0 / 0 / 0 / 0 / 2
CGTCTCGGCGGCGGCTGGGGCCGGGCAGCCAGATCCCCCCTGCCCGTGAAGCCGTGTCAAC / 0 / 0 / 0 / 1 / 0
CGTCTCGGCGGCGGCTGGGGCCGGGCGGCCAGATCCCCCCTGCCCGCGAAGCCGTGTCAAC / 0 / 0 / 0 / 0 / 1
CGTCTTGGAGACGGCTGGGGCCGGGCAGCCAGATCCCCCCTACCCGTGAAGCCGTGTCAAC / 0 / 1 / 0 / 0 / 0
CGTCTTGGCGACGGCTGGGGCCGGGCGGCCAGATCCCCCCTACCCGCGAAGCCGTGTCAAC / 1 / 0 / 1 / 1 / 0
Orphan allele / 0 / 0 / 0 / 2 / 80
Grand Total / 704 / 704 / 704 / 704 / 704

Supplementary table S1b Pooled Ethiopian ascertainment and NIEHS populations dataset (World dataset)

ELB / EM / FP / Clark-ancestral
EM / 0.997
FP / 0.999 / 0.999
Clark-ancestral / 0.991 / 0.989 / 0.991
Clark-common / 0.940 / 0.948 / 0.944 / 0.936

Supplementary table S2a Pooled Ethiopian ascertainment samples dataset