Supplementary Table 5. Prognostic Relevance of Combinations of Two Mutations

Supplementary Table 5. Prognostic relevance of combinations of two mutations.

0=TET2-/ASXL1-; 1=TET2-/ASXL1+; 2=TET2+/ASXL1-;3=TET2+/ASXL1+
0 vs 1 / 0.493 / 1 vs 0 / 0.493 / 2 vs 0 / 0.109 / 3 vs 0 / 0.11
0 vs 2 / 0.109 / 1 vs 2 / 0.219 / 2 vs 1 / 0.219 / 3 vs 1 / 0.067
0 vs 3 / 0.11 / 1 vs 3 / 0.067 / 2 vs 3 / 0.599 / 3 vs 2 / 0.599
0=ASXL1-/CBL-; 1=ASXL1+/CBL-; 2=ASXL1-/CBL+;3=ASXL1+/CBL+
0 vs 1 / 0.504 / 1 vs 0 / 0.504 / 2 vs 0 / 0.521 / 3 vs 0 / 0.897
0 vs 2 / 0.521 / 1 vs 2 / 0.942 / 2 vs 1 / 0.942 / 3 vs 1 / 0.542
0 vs 3 / 0.897 / 1 vs 3 / 0.542 / 2 vs 3 / 0.517 / 3 vs 2 / 0.517
0=ASXL1-/RAS-; 1=ASXL1+/RAS-; 2=ASXL1-/RAS+;3=ASXL1+/RAS+
0 vs 1 / 0.569 / 1 vs 0 / 0.569 / 2 vs 0 / 0.34 / 3 vs 0 / 0.221
0 vs 2 / 0.34 / 1 vs 2 / 0.765 / 2 vs 1 / 0.765 / 3 vs 1 / 0.743
0 vs 3 / 0.221 / 1 vs 3 / 0.743 / 2 vs 3 / 0.962 / 3 vs 2 / 0.962
0=EZH2-/ASXL1-; 1=EZH2-/ASXL1+; 2=EZH2+/ASXL1-;3=EZH2+/ASXL1+
0 vs 1 / 0.735 / 1 vs 0 / 0.735 / 2 vs 0 / 0.000 / 3 vs 0 / 0.944
0 vs 2 / 0.000 / 1 vs 2 / 0.002 / 2 vs 1 / 0.002 / 3 vs 1 / 0.775
0 vs 3 / 0.944 / 1 vs 3 / 0.775 / 2 vs 3 / 0.062 / 3 vs 2 / 0.062
0=EZH2-/RAS-; 1=EZH2-/RAS+; 2=EZH2+/RAS-;3=EZH2+/RAS+
0 vs 1 / 0.489 / 1 vs 0 / 0.489 / 2 vs 0 / 0.004 / 3 vs 0 / 0.512
0 vs 2 / 0.004 / 1 vs 2 / 0.001 / 2 vs 1 / 0.001 / 3 vs 1 / 0.141
0 vs 3 / 0.512 / 1 vs 3 / 0.141 / 2 vs 3 / 0.367 / 3 vs 2 / 0.367
0=EZH2-/CBL-; 1=EZH2-/CBL+; 2=EZH2+/CBL-;3=EZH2+/CBL+
0 vs 1 / 0.804 / 1 vs 0 / 0.804 / 2 vs 0 / 0.003 / 3 vs 0 / 0.204
0 vs 2 / 0.003 / 1 vs 2 / 0.039 / 2 vs 1 / 0.039 / 3 vs 1 / 0.492
0 vs 3 / 0.204 / 1 vs 3 / 0.492 / 2 vs 3 / 0.771 / 3 vs 2 / 0.771

P-values are given according to the Log Rank test for the respective pairwise comparisons of the four groups.