Supplementary Table 1. Multivariate Analysis of PTPN2 Gene Expression and Other Patient

Supplementary Table 1. Multivariate analysis of PTPN2 gene expression and other patient characteristics for major molecular response outcome within 24 months.

Variable / HR (95% CI) / p-value
PTPN2 gene expression (high vs low) / 0.216 (0.073-0.637) / 0.005
Age (continuous) / 1.008 (0.988-1.028) / 0.458
Gender (Male vs Female) / 0.602 (0.331-1.097) / 0.098
WCC (continuous) / 0.997 (0.991-1.003) / 0.3
Sokal risk score (overall) / 0.923
- low vs high / 0.981 (0.454-2.12) / 0.962
- intermediate vs high / 0.865 (0.384-1.948) / 0.726
A hazard ratio greater than 1 (less than 1) corresponds to a higher (lower) probability of achieving MMR by 24 months.
Abbreviations: CI, confidence interval; WCC, white cell counts; HR, hazard ratio; MMR, major molecular response
1-MMR by 24 months; 0-No MMR by 24 months