Supplemental Tables1. List of the 500 Most Significant Genes According to Increasing P Value

Supplemental TableS1. List of the 500 most significant genes according to increasing p value

Identifier / Gene name / Description / PC (gene vs. outcome) / Fold Change
NM_001025202 / STAG3L2 / stromal antigen 3-like 2 / 0.97 / 1.73
NM_002730 / PRKACA / protein kinase, cAMP-dependent, catalytic, alpha / -0.98 / 0.68
NM_017759 / INO80D / INO80 complex subunit D / 0.99 / 1.36
NM_182518 / unknown / unknown / 0.96 / 1.48
XM_374260 / unknown / unknown / -0.95 / 0.52
NM_058191 / unknown / unknown / 0.96 / 1.53
NM_005506 / SCARB2 / scavenger receptor class B, member 2 / 0.96 / 1.52
NM_030978 / ARPC5L / actin related protein 2/3 complex, subunit 5-like / -0.99 / 0.79
NM_025267 / AARSD1 / alanyl-tRNA synthetase domain containing 1 / 0.94 / 1.74
NM_001003652 / SMAD2 / SMAD family member 2 / 0.96 / 1.38
NM_016448 / DTL / denticleless homolog (Drosophila) / -0.95 / 0.63
NM_006101 / NDC80 / NDC80 homolog, kinetochore complex component (S. cerevisiae) / -0.95 / 0.65
NM_004950 / EPYC / epiphycan / -0.93 / 0.42
NM_018437 / HEMGN / hemogen / -0.93 / 0.5
NM_176884 / TAS2R43 / taste receptor, type 2, member 43 / 0.93 / 2.02
NM_033625 / RPL34 / ribosomal protein L34 / -0.95 / 0.7
NM_018991 / STAG3L1 / stromal antigen 3-like 1 / 0.93 / 1.7
NM_001039716 / DIO1 / deiodinase, iodothyronine, type I / 0.93 / 1.68
NM_015094 / HIC2 / hypermethylated in cancer 2 / -0.93 / 0.59
NM_001004056 / GRK4 / G protein-coupled receptor kinase 4 / -0.94 / 0.68
NM_004090 / DUSP3 / dual specificity phosphatase 3 / -0.94 / 0.69
NM_001013734 / RFPL4B / ret finger protein-like 4B / -0.93 / 0.68
NM_016185 / HN1 / hematological and neurological expressed 1 / -0.92 / 0.54
NM_017565 / FAM20A / family with sequence similarity 20, member A / 0.97 / 1.26
XM_926697 / unknown / unknown / 0.94 / 1.42
NM_018201 / TBC1D13 / TBC1 domain family, member 13 / -0.94 / 0.73
NM_002442 / MSI1 / musashi homolog 1 (Drosophila) / 0.94 / 1.38
NM_003814 / ADAM20 / ADAM metallopeptidase domain 20 / 0.94 / 1.37
NM_001024938 / SLC2A11 / solute carrier family 2 (facilitated glucose transporter), member 11 / 0.92 / 1.53
NM_018693 / unknown / unknown / 0.94 / 1.38
NM_016417 / GLRX5 / glutaredoxin 5 / -0.94 / 0.74
NM_014967 / FAN1 / FANCD2/FANCI-associated nuclease 1 / 0.92 / 1.49
NM_032260 / RGPD5 / RANBP2-like and GRIP domain containing 5 / 0.93 / 1.42
NM_175888 / ZNF620 / zinc finger protein 620 / 0.92 / 1.48
NM_017572 / MKNK2 / MAP kinase interacting serine/threonine kinase 2 / -0.92 / 0.63
NM_015074 / KIF1B / kinesin family member 1B / -0.92 / 0.65
NM_015059 / TLN2 / talin 2 / -0.92 / 0.63
NM_032195 / SON / SON DNA binding protein / 0.91 / 1.8
NM_032094 / unknown / unknown / 0.96 / 1.26
NM_006487 / FBLN1 / fibulin 1 / 0.91 / 1.67
NM_001004057 / GRK4 / G protein-coupled receptor kinase 4 / -0.93 / 0.73
NM_145308 / unknown / unknown / 0.92 / 1.45
XM_380146 / unknown / unknown / 0.91 / 1.68
NM_001005388 / NFASC / neurofascin / -0.91 / 0.57
NM_173343 / IL1R2 / interleukin 1 receptor, type II / -0.92 / 0.69
XM_925789 / unknown / unknown / 0.91 / 1.8
NM_001013739 / STAG3L3 / stromal antigen 3-like 3 / 0.9 / 1.84
NM_032048 / EMILIN2 / elastin microfibril interfacer 2 / -0.92 / 0.7
NM_006022 / TSC22D1 / TSC22 domain family, member 1 / 0.93 / 1.35
NM_006506 / RASA2 / RAS p21 protein activator 2 / 0.93 / 1.33
NM_016815 / GYPC / glycophorin C (Gerbich blood group) / -0.9 / 0.6
XM_926817 / unknown / unknown / 0.9 / 1.75
NM_005821 / unknown / unknown / 0.95 / 1.27
NM_153369 / KIAA1919 / KIAA1919 / 0.93 / 1.34
NM_022781 / RNF38 / ring finger protein 38 / 0.95 / 1.26
NM_016362 / GHRL / ghrelin/obestatin prepropeptide / 0.92 / 1.38
XM_372108 / unknown / unknown / 0.91 / 1.5
NM_001008394 / EID3 / EP300 interacting inhibitor of differentiation 3 / 0.92 / 1.4
NM_002888 / RARRES1 / retinoic acid receptor responder (tazarotene induced) 1 / 0.91 / 1.45
NM_021804 / ACE2 / angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 / -0.9 / 0.66
NM_001014839 / NCDN / neurochondrin / -0.91 / 0.7
XM_379483 / unknown / unknown / 0.91 / 1.4
NM_006264 / PTPN13 / protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) / -0.9 / 0.64
NM_173647 / RNF149 / ring finger protein 149 / 0.9 / 1.48
NM_001004340 / FCGR1B / Fc fragment of IgG, high affinity Ib, receptor (CD64) / 0.91 / 1.47
NM_144982 / ZFC3H1 / zinc finger, C3H1-type containing / 0.91 / 1.41
NM_018988 / GFOD1 / glucose-fructose oxidoreductase domain containing 1 / -0.9 / 0.66
XM_497711 / unknown / unknown / 0.89 / 2.26
NM_003212 / unknown / unknown / 0.9 / 1.51
NM_015327 / SMG5 / Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) / -0.91 / 0.7
NM_002083 / GPX2 / glutathione peroxidase 2 (gastrointestinal) / 0.9 / 1.5
NM_006985 / NPIP / nuclear pore complex interacting protein / 0.9 / 1.5
NM_014051 / TMEM14A / transmembrane protein 14A / -0.9 / 0.66
NM_012455 / PSD4 / pleckstrin and Sec7 domain containing 4 / -0.9 / 0.66
NM_001024216 / FBLIM1 / filamin binding LIM protein 1 / -0.89 / 0.59
NM_002101 / GYPC / glycophorin C (Gerbich blood group) / -0.89 / 0.62
NM_178121 / unknown / unknown / -0.91 / 0.74
NM_014959 / CARD8 / caspase recruitment domain family, member 8 / 0.91 / 1.41
NM_001039567 / RPS4Y2 / ribosomal protein S4, Y-linked 2 / 0.89 / 2.28
NM_207035 / unknown / unknown / 0.9 / 1.41
NM_017619 / RNPC3 / RNA-binding region (RNP1, RRM) containing 3 / 0.9 / 1.43
NM_138288 / C14orf147 / chromosome 14 open reading frame 147 / -0.92 / 0.77
NM_000995 / RPL34 / ribosomal protein L34 / -0.9 / 0.69
NM_032305 / POLR3GL / polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like / -0.91 / 0.75
XM_293293 / unknown / unknown / 0.88 / 1.95
NM_023928 / AACS / acetoacetyl-CoA synthetase / -0.91 / 0.73
NM_004168 / SDHA / succinate dehydrogenase complex, subunit A, flavoprotein (Fp) / 0.91 / 1.34
NM_001018088 / VPS13C / vacuolar protein sorting 13 homolog C (S. cerevisiae) / 0.92 / 1.3
NM_019063 / EML4 / echinoderm microtubule associated protein like 4 / 0.91 / 1.32
NM_001039382 / unknown / unknown / 0.88 / 2
NM_003635 / NDST2 / N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 / -0.9 / 0.71
NM_006145 / DNAJB1 / DnaJ (Hsp40) homolog, subfamily B, member 1 / -0.89 / 0.66
NM_015090 / NFASC / neurofascin / -0.88 / 0.58
NM_032737 / LMNB2 / lamin B2 / -0.89 / 0.68
NM_006132 / unknown / unknown / 0.89 / 1.5
NM_203307 / ZNF321 / zinc finger protein 321 / 0.88 / 1.62
NM_017896 / C20orf11 / chromosome 20 open reading frame 11 / -0.89 / 0.71
NM_016022 / APH1A / anterior pharynx defective 1 homolog A (C. elegans) / -0.93 / 0.8
NM_014463 / LSM3 / LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) / -0.96 / 0.83
NM_001018122 / unknown / unknown / 0.88 / 2.15
NM_152689 / unknown / unknown / 0.91 / 1.3
XM_209500 / unknown / unknown / 0.87 / 1.95
NM_020675 / SPC25 / SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) / -0.9 / 0.75
NM_001005472 / unknown / unknown / 0.89 / 1.41
NM_002936 / RNASEH1 / ribonuclease H1 / -0.91 / 0.78
XM_171032 / unknown / unknown / 0.88 / 1.8
NM_004442 / EPHB2 / EPH receptor B2 / -0.88 / 0.55
XM_291016 / unknown / unknown / -0.9 / 0.76
NM_006830 / UQCR11 / ubiquinol-cytochrome c reductase, complex III subunit XI / -0.9 / 0.74
NM_001002840 / STAG3L1 / stromal antigen 3-like 1 / 0.88 / 1.49
NM_018476 / BEX1 / brain expressed, X-linked 1 / 0.87 / 2.22
NM_134422 / unknown / unknown / 0.94 / 1.22
NM_024628 / SLC12A8 / solute carrier family 12 (potassium/chloride transporters), member 8 / -0.88 / 0.67
NM_020854 / KIAA1468 / KIAA1468 / 0.89 / 1.36
NM_022343 / GLIPR2 / GLI pathogenesis-related 2 / -0.88 / 0.61
XM_373814 / unknown / unknown / 0.87 / 1.79
NM_001005172 / OR52K2 / olfactory receptor, family 52, subfamily K, member 2 / 0.92 / 1.25
XM_925793 / unknown / unknown / 0.88 / 1.51
NM_007100 / ATP5I / ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E / -0.9 / 0.77
NM_006037 / HDAC4 / histone deacetylase 4 / -0.88 / 0.68
NM_014622 / VWA5A / von Willebrand factor A domain containing 5A / 0.88 / 1.57
NM_007020 / unknown / unknown / 0.88 / 1.44
NM_005192 / CDKN3 / cyclin-dependent kinase inhibitor 3 / -0.87 / 0.61
NM_014940 / MON1B / MON1 homolog B (yeast) / -0.89 / 0.75
NM_003784 / SERPINB7 / serpin peptidase inhibitor, clade B (ovalbumin), member 7 / -0.89 / 0.74
NM_015456 / COBRA1 / cofactor of BRCA1 / -0.89 / 0.75
NM_175932 / PSMD13 / proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 / 0.87 / 1.73
NM_176095 / unknown / unknown / 0.93 / 1.22
NM_024671 / ZNF768 / zinc finger protein 768 / -0.88 / 0.69
NM_001017995 / SH3PXD2B / SH3 and PX domains 2B / -0.87 / 0.62
NM_001002033 / HN1 / hematological and neurological expressed 1 / -0.87 / 0.59
NM_007010 / DDX52 / DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 / -0.93 / 0.82
NM_001039756 / unknown / unknown / 0.86 / 2.02
NM_005178 / BCL3 / B-cell CLL/lymphoma 3 / -0.9 / 0.76
NM_016002 / SCCPDH / saccharopine dehydrogenase (putative) / 0.87 / 1.65
XM_373985 / unknown / unknown / -0.87 / 0.66
XM_376043 / unknown / unknown / -0.89 / 0.77
NM_001002032 / HN1 / hematological and neurological expressed 1 / -0.87 / 0.58
NM_024735 / FBXO31 / F-box protein 31 / -0.88 / 0.72
NM_181305 / MRPL52 / mitochondrial ribosomal protein L52 / -0.94 / 0.83
NM_183422 / TSC22D1 / TSC22 domain family, member 1 / 0.91 / 1.24
NM_178581 / HM13 / histocompatibility (minor) 13 / 0.9 / 1.28
NM_033389 / SSH2 / slingshot homolog 2 (Drosophila) / -0.98 / 0.85
NM_014911 / AAK1 / AP2 associated kinase 1 / 0.87 / 1.46
XM_927271 / unknown / unknown / 0.88 / 1.42
NM_017709 / FAM46C / family with sequence similarity 46, member C / -0.87 / 0.64
NM_001010910 / unknown / unknown / -0.87 / 0.68
NM_001545 / ICT1 / immature colon carcinoma transcript 1 / -0.89 / 0.75
NM_004607 / TBCA / tubulin folding cofactor A / -0.94 / 0.83
NM_016265 / ZNF12 / zinc finger protein 12 / 0.93 / 1.21
NM_033343 / LHX4 / LIM homeobox 4 / 0.87 / 1.42
NM_001069 / TUBB2A / tubulin, beta 2A / -0.86 / 0.56
NM_002337 / LRPAP1 / low density lipoprotein receptor-related protein associated protein 1 / -0.89 / 0.75
NM_014919 / unknown / unknown / -0.88 / 0.73
NM_004107 / FCGRT / Fc fragment of IgG, receptor, transporter, alpha / -0.88 / 0.71
NM_006144 / GZMA / granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) / -0.86 / 0.51
NM_018434 / RNF130 / ring finger protein 130 / -0.89 / 0.77
NM_006990 / WASF2 / WAS protein family, member 2 / -0.87 / 0.66
NM_130847 / AMOTL1 / angiomotin like 1 / -0.88 / 0.72
XM_372816 / unknown / unknown / 0.86 / 2.16
NM_005650 / TCF20 / transcription factor 20 (AR1) / -0.88 / 0.73
NM_147166 / unknown / unknown / 0.86 / 1.56
NM_001145 / ANG / angiogenin, ribonuclease, RNase A family, 5 / -0.87 / 0.71
NM_003902 / FUBP1 / far upstream element (FUSE) binding protein 1 / 0.87 / 1.51
NM_014656 / unknown / unknown / -0.86 / 0.63
NM_025029 / MZT2B / mitotic spindle organizing protein 2B / -0.88 / 0.74
NM_018354 / C20orf46 / chromosome 20 open reading frame 46 / 0.86 / 2.12
NM_024873 / TNIP3 / TNFAIP3 interacting protein 3 / -0.92 / 0.82
NM_007353 / GNA12 / guanine nucleotide binding protein (G protein) alpha 12 / -0.9 / 0.8
NM_013308 / GPR171 / G protein-coupled receptor 171 / 0.86 / 2.06
NM_144571 / CNOT6L / CCR4-NOT transcription complex, subunit 6-like / 0.88 / 1.35
NM_148956 / NSUN5 / NOP2/Sun domain family, member 5 / 0.88 / 1.33
NM_022370 / ROBO3 / roundabout, axon guidance receptor, homolog 3 (Drosophila) / 0.9 / 1.25
NM_181469 / unknown / unknown / -0.88 / 0.76
XM_496129 / unknown / unknown / 0.86 / 1.77
NM_044472 / CDC42 / cell division cycle 42 (GTP binding protein, 25kDa) / 0.86 / 1.89
NM_005742 / PDIA6 / protein disulfide isomerase family A, member 6 / 0.9 / 1.26
NM_015949 / GET4 / golgi to ER traffic protein 4 homolog (S. cerevisiae) / -0.87 / 0.72
NM_006285 / TESK1 / testis-specific kinase 1 / -0.9 / 0.8
NM_002113 / CFHR1 / complement factor H-related 1 / -0.85 / 0.41
NM_015387 / MOBKL3 / MOB1, Mps One Binder kinase activator-like 3 (yeast) / 0.9 / 1.25
XM_211040 / unknown / unknown / 0.88 / 1.32
NM_152547 / BTNL9 / butyrophilin-like 9 / -0.85 / 0.31
NM_015677 / SH3YL1 / SH3 domain containing, Ysc84-like 1 (S. cerevisiae) / 0.86 / 1.5
NM_181704 / MLL3 / myeloid/lymphoid or mixed-lineage leukemia 3 / 0.88 / 1.33
NM_020829 / KIAA1432 / KIAA1432 / 0.89 / 1.29
NM_003809 / TNFSF12 / tumor necrosis factor (ligand) superfamily, member 12 / 0.88 / 1.32
NM_002254 / KIF3C / kinesin family member 3C / -0.86 / 0.64
NM_003813 / ADAM21 / ADAM metallopeptidase domain 21 / 0.88 / 1.31
NM_015043 / TBC1D9B / TBC1 domain family, member 9B (with GRAM domain) / -0.87 / 0.73
NM_004640 / BAT1 / HLA-B associated transcript 1 / 0.87 / 1.34
NM_012477 / WBP1 / WW domain binding protein 1 / 0.87 / 1.38
NM_007202 / AKAP10 / A kinase (PRKA) anchor protein 10 / 0.88 / 1.31
NM_033421 / SNX21 / sorting nexin family member 21 / -0.87 / 0.73
NM_021956 / GRIK2 / glutamate receptor, ionotropic, kainate 2 / 0.87 / 1.36
NM_022037 / TIA1 / TIA1 cytotoxic granule-associated RNA binding protein / 0.86 / 1.46
NM_001032372 / ZNF226 / zinc finger protein 226 / 0.91 / 1.22
NM_002957 / RXRA / retinoid X receptor, alpha / -0.86 / 0.66
NM_001315 / MAPK14 / mitogen-activated protein kinase 14 / -0.88 / 0.78
NM_014268 / MAPRE2 / microtubule-associated protein, RP/EB family, member 2 / -0.86 / 0.65
NM_000398 / CYB5R3 / cytochrome b5 reductase 3 / -0.85 / 0.61
NM_003939 / BTRC / beta-transducin repeat containing / -0.93 / 0.84
NM_018639 / WSB2 / WD repeat and SOCS box-containing 2 / -0.87 / 0.73
NM_012304 / FBXL7 / F-box and leucine-rich repeat protein 7 / -0.85 / 0.63
XM_927481 / unknown / unknown / 0.86 / 1.5
NM_001012761 / RGMB / RGM domain family, member B / -0.86 / 0.67
XM_927048 / unknown / unknown / 0.85 / 1.81
XM_373338 / unknown / unknown / 0.86 / 1.54
NM_080626 / BRI3BP / BRI3 binding protein / -0.88 / 0.77
NM_033514 / LIMS3 / LIM and senescent cell antigen-like domains 3 / 0.85 / 1.77
NM_033201 / C16orf45 / chromosome 16 open reading frame 45 / -0.85 / 0.62
NM_002963 / S100A7 / S100 calcium binding protein A7 / -0.93 / 0.84
NM_001999 / FBN2 / fibrillin 2 / 0.95 / 1.17
XM_926355 / unknown / unknown / 0.85 / 1.75
NM_024665 / TBL1XR1 / transducin (beta)-like 1 X-linked receptor 1 / 0.87 / 1.31
NM_006051 / APBB3 / amyloid beta (A4) precursor protein-binding, family B, member 3 / 0.91 / 1.21
NM_002334 / LRP4 / low density lipoprotein receptor-related protein 4 / -0.88 / 0.78
NM_024718 / C9orf86 / chromosome 9 open reading frame 86 / -0.86 / 0.72
NM_001013714 / unknown / unknown / 0.84 / 2.15
XM_927253 / unknown / unknown / 0.85 / 1.53
XM_496214 / unknown / unknown / 0.85 / 1.68
NM_001012753 / ZNF763 / zinc finger protein 763 / 0.85 / 1.49
NM_024805 / RBFA / ribosome binding factor A (putative) / 0.85 / 1.44
NM_025196 / GRPEL1 / GrpE-like 1, mitochondrial (E. coli) / -0.88 / 0.79
NM_013400 / REPIN1 / replication initiator 1 / -0.86 / 0.71
NM_020633 / VN1R1 / vomeronasal 1 receptor 1 / 0.86 / 1.41
XM_166966 / unknown / unknown / 0.85 / 1.49
NM_145080 / NSMCE1 / non-SMC element 1 homolog (S. cerevisiae) / -0.87 / 0.76
NM_005741 / ZNF263 / zinc finger protein 263 / -0.88 / 0.8
XM_055481 / unknown / unknown / 0.85 / 1.4
NM_002024 / FMR1 / fragile X mental retardation 1 / 0.94 / 1.17
NM_005570 / LMAN1 / lectin, mannose-binding, 1 / 0.85 / 1.42
XM_928114 / unknown / unknown / 0.86 / 1.38
NM_080822 / OVCA2 / ovarian tumor suppressor candidate 2 / -0.87 / 0.76
NM_005525 / HSD11B1 / hydroxysteroid (11-beta) dehydrogenase 1 / -0.87 / 0.78
NM_001039499 / unknown / unknown / 0.84 / 1.88
NM_004219 / PTTG1 / pituitary tumor-transforming 1 / -0.85 / 0.7
NM_021806 / FAM3A / family with sequence similarity 3, member A / 0.85 / 1.51
XM_039676 / unknown / unknown / 0.84 / 1.63
XM_926361 / unknown / unknown / 0.84 / 1.81
XM_925780 / unknown / unknown / 0.85 / 1.47
NM_021219 / JAM2 / junctional adhesion molecule 2 / -0.85 / 0.66
NM_176885 / TAS2R43 / taste receptor, type 2, member 43 / 0.84 / 1.88
XM_925816 / unknown / unknown / 0.86 / 1.31
NM_001010896 / C10orf113 / chromosome 10 open reading frame 113 / 0.84 / 2.07
NM_170681 / GFM2 / G elongation factor, mitochondrial 2 / 0.85 / 1.5
NM_020310 / MNT / MAX binding protein / -0.85 / 0.7
XM_926594 / unknown / unknown / 0.85 / 1.46
NM_005299 / GPR31 / G protein-coupled receptor 31 / 0.85 / 1.43
NM_032604 / ABHD1 / abhydrolase domain containing 1 / -0.86 / 0.75
NM_022825 / PORCN / porcupine homolog (Drosophila) / -0.85 / 0.67
XM_212326 / unknown / unknown / 0.83 / 3.3
NM_206996 / SPAG17 / sperm associated antigen 17 / 0.87 / 1.27
NM_001003794 / MGLL / monoglyceride lipase / -0.85 / 0.69
NM_007308 / SNCA / synuclein, alpha (non A4 component of amyloid precursor) / -0.85 / 0.7
NM_152305 / POGLUT1 / protein O-glucosyltransferase 1 / 0.87 / 1.27
NM_001001786 / BLID / BH3-like motif containing, cell death inducer / 0.84 / 1.56
NM_032792 / ZBTB45 / zinc finger and BTB domain containing 45 / -0.86 / 0.77
NM_006256 / PKN2 / protein kinase N2 / 0.87 / 1.29
NM_004255 / COX5A / cytochrome c oxidase subunit Va / -0.88 / 0.8
NM_001031734 / FDX1L / ferredoxin 1-like / -0.84 / 0.66
NM_003810 / TNFSF10 / tumor necrosis factor (ligand) superfamily, member 10 / -0.84 / 0.64
NM_033542 / SYS1 / SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae) / -0.87 / 0.79
NM_013329 / GCFC1 / GC-rich sequence DNA-binding factor 1 / 0.85 / 1.38
XM_370839 / unknown / unknown / 0.84 / 1.56
NM_144570 / HN1L / hematological and neurological expressed 1-like / -0.85 / 0.74
NM_002473 / MYH9 / myosin, heavy chain 9, non-muscle / -0.89 / 0.82
NM_001004685 / OR2F2 / olfactory receptor, family 2, subfamily F, member 2 / 0.85 / 1.35
NM_001187 / unknown / unknown / 0.84 / 1.66
NM_001013655 / unknown / unknown / 0.83 / 1.78
NM_023930 / KCTD14 / potassium channel tetramerisation domain containing 14 / -0.83 / 0.57
NM_002099 / GYPA / glycophorin A (MNS blood group) / -0.83 / 0.51
NM_032971 / PCDH11Y / protocadherin 11 Y-linked / 0.84 / 1.66
NM_052865 / C20orf72 / chromosome 20 open reading frame 72 / -0.86 / 0.76
NM_021870 / FGG / fibrinogen gamma chain / -0.83 / 0.34
NM_176882 / TAS2R40 / taste receptor, type 2, member 40 / 0.84 / 1.52
NM_144490 / unknown / unknown / 0.83 / 1.74
NM_001007260 / unknown / unknown / 0.85 / 1.41
XM_378908 / unknown / unknown / -0.88 / 0.81
NM_001005920 / JMJD8 / jumonji domain containing 8 / -0.87 / 0.79
NM_006880 / unknown / unknown / 0.86 / 1.32
NM_006221 / PIN1 / peptidylprolyl cis/trans isomerase, NIMA-interacting 1 / -0.84 / 0.68
NM_004209 / SYNGR3 / synaptogyrin 3 / -0.86 / 0.76
NM_024845 / NAT15 / N-acetyltransferase 15 (GCN5-related, putative) / -0.84 / 0.7
NM_001271 / CHD2 / chromodomain helicase DNA binding protein 2 / 0.83 / 1.74
XM_927729 / unknown / unknown / 0.84 / 1.5
NM_031407 / HUWE1 / HECT, UBA and WWE domain containing 1 / -0.88 / 0.81
NM_181865 / ACOT7 / acyl-CoA thioesterase 7 / -0.94 / 0.86
NM_024623 / OGFOD2 / 2-oxoglutarate and iron-dependent oxygenase domain containing 2 / -0.89 / 0.83
NM_006467 / POLR3G / polymerase (RNA) III (DNA directed) polypeptide G (32kD) / 0.83 / 1.66
NM_001002017 / HCFC1R1 / host cell factor C1 regulator 1 (XPO1 dependent) / -0.85 / 0.74
NM_178336 / MRPL52 / mitochondrial ribosomal protein L52 / -0.92 / 0.85
NM_006065 / SIRPB1 / signal-regulatory protein beta 1 / 0.86 / 1.3
XM_370958 / unknown / unknown / 0.83 / 1.53
NM_018347 / C20orf29 / chromosome 20 open reading frame 29 / -0.84 / 0.72
NM_173517 / VKORC1L1 / vitamin K epoxide reductase complex, subunit 1-like 1 / -0.85 / 0.76
NM_001199 / BMP1 / bone morphogenetic protein 1 / 0.84 / 1.38
XM_927909 / unknown / unknown / -0.82 / 0.19
NM_016630 / SPG21 / spastic paraplegia 21 (autosomal recessive, Mast syndrome) / 0.91 / 1.18
NM_032802 / unknown / unknown / 0.89 / 1.2
NM_017652 / ZNF586 / zinc finger protein 586 / 0.83 / 1.66
NM_182523 / CMC1 / COX assembly mitochondrial protein homolog (S. cerevisiae) / -0.84 / 0.71
NM_198941 / SERINC3 / serine incorporator 3 / 0.9 / 1.2
NM_001007239 / METTL13 / methyltransferase like 13 / -0.84 / 0.72
XM_927426 / unknown / unknown / 0.82 / 1.99
NM_005067 / SIAH2 / seven in absentia homolog 2 (Drosophila) / -0.85 / 0.74
XM_372109 / unknown / unknown / 0.85 / 1.32
NM_022063 / C10orf84 / chromosome 10 open reading frame 84 / 0.88 / 1.22
NM_025197 / unknown / unknown / 0.85 / 1.34
NM_017979 / unknown / unknown / 0.84 / 1.39
NM_004793 / LONP1 / lon peptidase 1, mitochondrial / -0.86 / 0.79
XM_378914 / unknown / unknown / 0.83 / 1.65
NM_001018109 / PIR / pirin (iron-binding nuclear protein) / -0.84 / 0.7
NM_001007246 / BRWD1 / bromodomain and WD repeat domain containing 1 / 0.83 / 1.43
XM_928191 / unknown / unknown / 0.83 / 1.59
NM_032525 / TUBB6 / tubulin, beta 6 / -0.83 / 0.66
NM_000379 / XDH / xanthine dehydrogenase / -0.82 / 0.52
NM_014453 / CHMP2A / chromatin modifying protein 2A / -0.89 / 0.83
NM_001004322 / unknown / unknown / 0.83 / 1.55
NM_032167 / RUNDC2A / RUN domain containing 2A / 0.83 / 1.49
XM_496847 / unknown / unknown / 0.83 / 1.43
NM_004633 / IL1R2 / interleukin 1 receptor, type II / -0.82 / 0.59
NM_021932 / RIC8A / resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) / -0.84 / 0.74
NM_006131 / unknown / unknown / 0.83 / 1.54
XM_496150 / unknown / unknown / 0.83 / 1.48
NM_002488 / NDUFA2 / NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa / -0.84 / 0.75
XM_496852 / unknown / unknown / 0.82 / 2.28
NM_005585 / SMAD6 / SMAD family member 6 / -0.84 / 0.75
NM_001002018 / HCFC1R1 / host cell factor C1 regulator 1 (XPO1 dependent) / -0.83 / 0.71
NM_022662 / ANAPC1 / anaphase promoting complex subunit 1 / -0.84 / 0.74
NM_005713 / COL4A3BP / collagen, type IV, alpha 3 (Goodpasture antigen) binding protein / 0.83 / 1.53
NM_001001716 / NFKBIB / nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta / -0.83 / 0.72
NM_001039761 / unknown / unknown / 0.82 / 1.67
NM_015470 / RAB11FIP5 / RAB11 family interacting protein 5 (class I) / -0.83 / 0.7
NM_000268 / NF2 / neurofibromin 2 (merlin) / -0.84 / 0.73
NM_005788 / PRMT3 / protein arginine methyltransferase 3 / 0.86 / 1.24
NM_017668 / NDE1 / nudE nuclear distribution gene E homolog 1 (A. nidulans) / -0.85 / 0.78
NM_013359 / ZNF230 / zinc finger protein 230 / 0.82 / 1.63
NM_001745 / CAMLG / calcium modulating ligand / -0.89 / 0.84
NM_199340 / LRRC37A3 / leucine rich repeat containing 37, member A3 / 0.84 / 1.35
NM_203299 / C9orf131 / chromosome 9 open reading frame 131 / 0.83 / 1.49
NM_012291 / ESPL1 / extra spindle pole bodies homolog 1 (S. cerevisiae) / -0.82 / 0.66
NM_018281 / ECHDC2 / enoyl CoA hydratase domain containing 2 / 0.91 / 1.17
XM_926894 / unknown / unknown / 0.82 / 1.9
XM_086001 / unknown / unknown / 0.82 / 1.57
NM_032307 / C9orf64 / chromosome 9 open reading frame 64 / -0.89 / 0.84
NM_199054 / MKNK2 / MAP kinase interacting serine/threonine kinase 2 / -0.83 / 0.7
NM_182481 / unknown / unknown / 0.85 / 1.27
NM_001013717 / C5orf56 / chromosome 5 open reading frame 56 / 0.84 / 1.34
NM_017640 / LRRC16A / leucine rich repeat containing 16A / -0.85 / 0.79
XM_926505 / unknown / unknown / 0.83 / 1.44
NM_014323 / PATZ1 / POZ (BTB) and AT hook containing zinc finger 1 / -0.88 / 0.84
NM_032174 / TOMM40L / translocase of outer mitochondrial membrane 40 homolog (yeast)-like / -0.84 / 0.75
NM_001003688 / SMAD1 / SMAD family member 1 / -0.83 / 0.73
XM_926998 / unknown / unknown / 0.82 / 1.47
XM_927488 / unknown / unknown / 0.82 / 1.82
NM_007170 / TESK2 / testis-specific kinase 2 / -0.83 / 0.73
NM_153445 / OR5P3 / olfactory receptor, family 5, subfamily P, member 3 / 0.81 / 2.16
NM_001039782 / unknown / unknown / 0.82 / 1.82
XM_926115 / unknown / unknown / 0.82 / 1.72
NM_181814 / ABHD12B / abhydrolase domain containing 12B / 0.85 / 1.28
NM_017885 / HCFC1R1 / host cell factor C1 regulator 1 (XPO1 dependent) / -0.83 / 0.72
NM_024841 / PRR5L / proline rich 5 like / -0.82 / 0.67
NM_017919 / STX17 / syntaxin 17 / 0.89 / 1.19
NM_021213 / PCTP / phosphatidylcholine transfer protein / -0.84 / 0.78
NM_000096 / CP / ceruloplasmin (ferroxidase) / -0.81 / 0.44
NM_152622 / MIER3 / mesoderm induction early response 1, family member 3 / 0.82 / 1.42
NM_018044 / NSUN5 / NOP2/Sun domain family, member 5 / 0.83 / 1.34
NM_031966 / CCNB1 / cyclin B1 / -0.83 / 0.72
NM_174940 / TMEM80 / transmembrane protein 80 / 0.84 / 1.28
NM_020382 / SETD8 / SET domain containing (lysine methyltransferase) 8 / -0.84 / 0.77
NM_001005417 / B4GALT2 / UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 / -0.84 / 0.77
XM_926270 / unknown / unknown / 0.81 / 1.73
NM_001033506 / CSTF3 / cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa / 0.81 / 1.87
NM_198066 / GNPNAT1 / glucosamine-phosphate N-acetyltransferase 1 / -0.83 / 0.74
XM_928130 / unknown / unknown / 0.84 / 1.27
NM_206824 / VKORC1 / vitamin K epoxide reductase complex, subunit 1 / -0.83 / 0.76
NM_001006938 / TCEAL6 / transcription elongation factor A (SII)-like 6 / -0.84 / 0.77
NM_199242 / UNC13D / unc-13 homolog D (C. elegans) / -0.85 / 0.8
NM_001039671 / YIF1B / Yip1 interacting factor homolog B (S. cerevisiae) / -0.97 / 0.88
NM_138802 / ZFAND2B / zinc finger, AN1-type domain 2B / -0.84 / 0.79
XM_926501 / unknown / unknown / 0.81 / 1.72
NM_199123 / SETD3 / SET domain containing 3 / 0.88 / 1.19
NM_018376 / NIPSNAP3B / nipsnap homolog 3B (C. elegans) / 0.86 / 1.22
NM_001017395 / TMCC1 / transmembrane and coiled-coil domain family 1 / -0.83 / 0.75
NM_005386 / NNAT / neuronatin / -0.81 / 0.56
NM_007185 / CELF3 / CUGBP, Elav-like family member 3 / 0.81 / 1.59
NM_207357 / unknown / unknown / 0.82 / 1.39
NM_014972 / TCF25 / transcription factor 25 (basic helix-loop-helix) / 0.82 / 1.38
NM_001065 / TNFRSF1A / tumor necrosis factor receptor superfamily, member 1A / -0.84 / 0.79
NM_144964 / RG9MTD3 / RNA (guanine-9-) methyltransferase domain containing 3 / 0.82 / 1.5
NM_152509 / unknown / unknown / 0.82 / 1.5
NM_000677 / ADORA3 / adenosine A3 receptor / -0.81 / 0.56
NM_005194 / CEBPB / CCAAT/enhancer binding protein (C/EBP), beta / -0.85 / 0.81
NM_018140 / CEP72 / centrosomal protein 72kDa / -0.82 / 0.71
XM_928022 / unknown / unknown / 0.84 / 1.28
NM_017895 / DDX27 / DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 / -0.87 / 0.84
NM_014431 / KIAA1274 / KIAA1274 / -0.83 / 0.77
NM_015203 / RPRD2 / regulation of nuclear pre-mRNA domain containing 2 / 0.82 / 1.35
NM_145328 / unknown / unknown / 0.82 / 1.35
NM_015116 / LRCH1 / leucine-rich repeats and calponin homology (CH) domain containing 1 / 0.81 / 1.5
NM_018141 / MRPS10 / mitochondrial ribosomal protein S10 / -0.86 / 0.82
NM_030908 / OR2A4 / olfactory receptor, family 2, subfamily A, member 4 / 0.81 / 1.87
NM_173500 / TTBK2 / tau tubulin kinase 2 / 0.82 / 1.35
NM_016612 / SLC25A37 / solute carrier family 25, member 37 / -0.82 / 0.72
NM_054107 / OR1J2 / olfactory receptor, family 1, subfamily J, member 2 / 0.83 / 1.33
NM_006534 / NCOA3 / nuclear receptor coactivator 3 / 0.85 / 1.23
XM_499338 / unknown / unknown / 0.81 / 1.7
NM_005279 / GPR1 / G protein-coupled receptor 1 / -0.8 / 0.51
NM_002440 / MSH4 / mutS homolog 4 (E. coli) / 0.84 / 1.27
NM_001889 / CRYZ / crystallin, zeta (quinone reductase) / 0.81 / 1.49
NM_006835 / CCNI / cyclin I / -0.85 / 0.82
XM_294802 / unknown / unknown / 0.8 / 1.85
NM_013282 / UHRF1 / ubiquitin-like with PHD and ring finger domains 1 / -0.86 / 0.83
NM_181513 / unknown / unknown / -0.83 / 0.75
NM_206912 / unknown / unknown / 0.81 / 1.58
NM_152272 / CHMP7 / CHMP family, member 7 / -0.85 / 0.81
NM_003899 / ARHGEF7 / Rho guanine nucleotide exchange factor (GEF) 7 / -0.87 / 0.84
NM_201626 / USP33 / ubiquitin specific peptidase 33 / 0.82 / 1.37
NM_018410 / HJURP / Holliday junction recognition protein / -0.84 / 0.79
NM_024519 / FAM65A / family with sequence similarity 65, member A / -0.87 / 0.83
NM_130390 / unknown / unknown / 0.81 / 1.48
NM_032478 / MRPL38 / mitochondrial ribosomal protein L38 / -0.82 / 0.74
NM_016565 / CHCHD8 / coiled-coil-helix-coiled-coil-helix domain containing 8 / -0.83 / 0.76
XM_496905 / unknown / unknown / 0.81 / 1.64
XM_928202 / unknown / unknown / 0.87 / 1.2
NM_014444 / TUBGCP4 / tubulin, gamma complex associated protein 4 / 0.86 / 1.2
NM_032322 / RNF135 / ring finger protein 135 / -0.83 / 0.76
XM_926447 / unknown / unknown / 0.8 / 2.06
XM_039218 / unknown / unknown / 0.86 / 1.21
NM_001321 / CSRP2 / cysteine and glycine-rich protein 2 / -0.82 / 0.75
NM_018233 / OGFOD1 / 2-oxoglutarate and iron-dependent oxygenase domain containing 1 / -0.81 / 0.68
NM_017503 / SURF2 / surfeit 2 / -0.81 / 0.72
NM_001130 / AES / amino-terminal enhancer of split / -0.82 / 0.75
NM_004671 / PIAS2 / protein inhibitor of activated STAT, 2 / -0.82 / 0.75
XM_352159 / unknown / unknown / 0.81 / 1.53
NM_001005526 / SF3B1 / splicing factor 3b, subunit 1, 155kDa / 0.81 / 1.4
XM_926614 / unknown / unknown / 0.8 / 1.7
NM_005072 / SLC12A4 / solute carrier family 12 (potassium/chloride transporters), member 4 / -0.82 / 0.74
XM_927717 / unknown / unknown / 0.8 / 1.89
NM_000074 / CD40LG / CD40 ligand / -0.85 / 0.82
NM_015274 / MAN2B2 / mannosidase, alpha, class 2B, member 2 / -0.82 / 0.74
NM_177458 / LYNX1 / Ly6/neurotoxin 1 / 0.83 / 1.28
NM_002023 / FMOD / fibromodulin / 0.81 / 1.42
NM_003769 / SRSF9 / serine/arginine-rich splicing factor 9 / -0.83 / 0.79
NM_004237 / TRIP13 / thyroid hormone receptor interactor 13 / -0.81 / 0.68
NM_001033583 / ACOT9 / acyl-CoA thioesterase 9 / -0.81 / 0.72
NM_001008222 / ZDHHC9 / zinc finger, DHHC-type containing 9 / -0.82 / 0.77
NM_017588 / WDR5 / WD repeat domain 5 / -0.82 / 0.74
NM_013398 / ZNF224 / zinc finger protein 224 / 0.82 / 1.32
NM_000142 / FGFR3 / fibroblast growth factor receptor 3 / -0.81 / 0.68
XM_926025 / unknown / unknown / 0.82 / 1.3
NM_032158 / unknown / unknown / 0.84 / 1.23
NM_002355 / M6PR / mannose-6-phosphate receptor (cation dependent) / 0.82 / 1.3
SYNTHESIS_SET16 / unknown / unknown / 0.96 / 1.13
NM_207485 / unknown / unknown / 0.8 / 1.69
NM_014879 / P2RY14 / purinergic receptor P2Y, G-protein coupled, 14 / 0.8 / 1.63
XM_496034 / unknown / unknown / 0.81 / 1.39
NM_015332 / NUDCD3 / NudC domain containing 3 / -0.82 / 0.77
NM_015120 / ALMS1 / Alstrom syndrome 1 / -0.81 / 0.68
XM_926511 / unknown / unknown / 0.81 / 1.46
NM_032926 / TCEAL3 / transcription elongation factor A (SII)-like 3 / -0.81 / 0.7
NM_005380 / NBL1 / neuroblastoma, suppression of tumorigenicity 1 / -0.8 / 0.54
NM_052888 / LRRC37B / leucine rich repeat containing 37B / 0.82 / 1.28
NM_001005862 / ERBB2 / v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) / -0.82 / 0.77
XM_927577 / unknown / unknown / 0.8 / 1.99
NM_173728 / ARHGEF15 / Rho guanine nucleotide exchange factor (GEF) 15 / -0.81 / 0.7
NM_005796 / NUTF2 / nuclear transport factor 2 / -0.84 / 0.82
NM_016633 / AHSP / alpha hemoglobin stabilizing protein / -0.85 / 0.83
NM_014580 / SLC2A8 / solute carrier family 2 (facilitated glucose transporter), member 8 / -0.81 / 0.7
NM_017944 / USP47 / ubiquitin specific peptidase 47 / -0.82 / 0.76
NM_005395 / unknown / unknown / 0.82 / 1.33
XM_925794 / unknown / unknown / 0.8 / 1.86
NM_002436 / MPP1 / membrane protein, palmitoylated 1, 55kDa / -0.82 / 0.76
NM_004045 / ATOX1 / ATX1 antioxidant protein 1 homolog (yeast) / -0.82 / 0.78
NM_013443 / ST6GALNAC6 / ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 / -0.88 / 0.85
NM_178335 / CCDC50 / coiled-coil domain containing 50 / 0.81 / 1.33
XM_370728 / unknown / unknown / 0.81 / 1.34
XM_372143 / unknown / unknown / -0.83 / 0.79
NM_152392 / AHSA2 / AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast) / 0.8 / 1.61
NM_018055 / NODAL / nodal homolog (mouse) / 0.83 / 1.26
NM_001813 / CENPE / centromere protein E, 312kDa / -0.8 / 0.69
XM_926838 / unknown / unknown / 0.81 / 1.4
NM_014851 / KLHL21 / kelch-like 21 (Drosophila) / 0.92 / 1.14
XM_056455 / unknown / unknown / -0.8 / 0.64
NM_012167 / unknown / unknown / 0.81 / 1.39
NM_022102 / unknown / unknown / -0.84 / 0.82
NM_015545 / PTCD1 / pentatricopeptide repeat domain 1 / -0.82 / 0.79
XM_379273 / unknown / unknown / 0.82 / 1.3
NM_001976 / ENO3 / enolase 3 (beta, muscle) / 0.8 / 1.43
NM_002048 / GAS1 / growth arrest-specific 1 / -0.8 / 0.64
NM_021013 / KRT34 / keratin 34 / -0.79 / 0.38
NM_005935 / AFF1 / AF4/FMR2 family, member 1 / 0.83 / 1.25
NM_144781 / PDCD2 / programmed cell death 2 / 0.82 / 1.28
XM_497141 / unknown / unknown / 0.79 / 2.03
NM_001017986 / FCGR1B / Fc fragment of IgG, high affinity Ib, receptor (CD64) / 0.8 / 1.43
NM_012484 / HMMR / hyaluronan-mediated motility receptor (RHAMM) / -0.81 / 0.74
NM_025135 / FHOD3 / formin homology 2 domain containing 3 / -0.81 / 0.74
NM_002032 / FTH1 / ferritin, heavy polypeptide 1 / -0.8 / 0.64
XM_926140 / unknown / unknown / 0.81 / 1.36

PC : Pearson correlation to the outcome attribute

Supplemental Table S2.Primer sequences and PCR amplification conditions

Gene / Forward primer / Reverse primer / Annealing T
SDHA / TACAAGGTGCGGATTGATGA / CAAAGGGCTTCTTCTGTTGC / 55°
TBP / TGCACAGGAGCCAAGAGTGAA / CACATCACAGCTCCCCACCA / 55°
LEP / AAGGTTTGGTGTGTCGAGATG / CTCCTGTCTCTTCTTTCTCTGC / 55°
IGFBP1 / AGTACCTATGATGGCTCGAA / TTGGAAATTTCTTCTCCTGA / 55°
RBP4 / TCCAGAAAGGAAATGATGAC / AAAACACGAAGGAGTAGCTG / 55°