2015 Inter-CFAR HIV/TB Symposium
November 4, 2015
Seattle Grand Hyatt Hotel – Princessa Ballroom Section 1
7:30-8:00 Breakfast / Poster set-up
8:00 -8:15 am:Welcome remarks – Goalsof the meeting - Ron Collman(Penn CFAR) and Tom Hawn (Univ. Washington CFAR)
8:15-9:00 am:Keynote Lecture - Willem Hanekom – Deputy Director, TB Unit – Bill & Melinda Gates Foundation “Update on TB Vaccines – the Global Landscape and Research Priorities”
9:00-9:30am:Speaker–Jerrold Ellner(Boston University / Lifespan-Tufts-BrownCFAR):“TB Biomarkers”
9:30– 10:15 am:Oral Abstracts in TB Biomarkers: Three 10 min/speaker segments & 5 min for questions: Session moderator: TBN
Toidi Adekembi – Emory CFAR
T Cell Biomarkers during Treatment of HIV/TB
Christina Yoon – UCSF-GIVI CFAR
C-reactive Protein-based TB Screening to Improve the Efficiency and Reduce the Cost of Intensified Case-finding Among People Living with HIV
George Makedonas –Baylor-UT CFAR
Correlates of TB Disease Progression in People Living with HIV
10:15–10:30 am:Break and Networking
10:30– 11:00 am: Speaker –Tom Hawn(Univ. Washington / UW CFAR):“TB Susceptibility”
11:00 – 11:30am: Speaker - Anne Goldfeld (Harvard CFAR):“TB/HIV Immune Pathogenesis”
11:30– 12:15 pm:Oral Abstracts in Immunology: Three 10 min/speaker segments & 5 min for questions:Session moderator: TBD
Cheryl Day –Emory CFAR
Distinct Subsets of Mycobacterium tuberculosis-specific CD4 T Cells are Depleted in HIV co-Infected Individuals with Latent TB Infection
Carina Marquez – UCSF-GIVI CFAR
TB Infection in Early Childhood in Uganda and the Influence of HIV Exposure
Elisa Nemes – Univ. of Cape Town / Miami CFAR
Host Correlates of Risk of BCG Immune Reconstitution Inflammatory Syndrome (IRIS) in HIV+ Children Starting ART
12:15–1:45 pm:Poster Session and Lunch
1:45 – 2:15 pm:Speaker Richard Chaisson (Johns Hopkins CFAR): “Latent TB in HIV”
2:15–2:45 pm:Speaker David Tobin (Duke CFAR): “TB Host-Directed Therapy (HDT)”
2:45– 3:15 pm:Oral Abstracts in HDT: Two 10 min/speaker segments & 5 min for questions: Session moderators: TBN
Stefan Oehlers –Duke CFAR
The Role of Vascular Dysfunction during Mycobacterial Infection
Jim Sun –Univ. of Alabama CFAR
Altered PPM1A Phosphatase Expression Directly Links Mycobacterium tuberculosis Infection to Increased HIV-1 Susceptibility in Macrophages
3:15– 3:30 pm:Break and Networking
3:30– 4:00 pm:Speaker –David Horne(Univ. Washington CFAR) –Diagnosis of TBin HIV
4:00– 4:30 pm:Speaker – Gregory Bisson(Penn CFAR) – Empiric TB treatment in HIV
4:30– 5:15 pm:Oral abstracts in Diagnosis/Treatment: Three 10 min/speaker segments & 5 min for questions: Session moderators: TBN
Daniel Meressa – Global Health Committee, Addis Ababa / Harvard CFAR
Achieving High Treatment Success for Multidrug-Resistant Tuberculosis with HIV co-infection in Africa: Initiation and Scale-up of MDR-TB Care in Ethiopia
Sumona Chaudhury – Harvard CFAR
Predictors of Mortality Among Children co-Infected with HIV and TB in Tanzania
Lydia Nakiyingi – Makerere University, Kampala / Lifespan-Tufts-BrownCFAR)
Predictors of Outcomes of Mycobacteremia among HIV-infected Smear-Negative Presumptive TB Patients in Uganda
5:15 – 5:45 pm:Discussion & Wrap-up: Inter-CFAR Collaborations & Opportunities - Ron Collmanand Tom Hawn
5:45– 6:15 pm:Break and Networking / Remove Posters
6:15- 8:30 pm:Dinner
6:45- 8:15 pmDinner Program Presentations:
Peter Kim, NIH/NIAID – Funding Priorities & Initiatives at NIH/NIAID (10 minutes)
Robert Mahon, NIH/NIAID- Integrating Immunometabolism and Immuno-oncology Advances into the Development of MTB HDT (20 minutes)
Lakshmi Jayashankar, NIH/NIAID–HIV/TB: Biomarkers and TB vaccines (20 minutes)
15 minutes open discussion
Willem Hanekom, Gates Foundation–Funding Priorities & Initiatives at the Gates Foundation(15 minutes followed by 10 minutes discussion)