Scientific Research and Advocacy on Adherence to Medical Plan: a consortium to ground evidence-based insights into clinical practice

Elísio Costa1, Anna Giardini2, Quilici Sibilia3, Enrica Menditto4, Iris Marr5, AntonioGimeno6, Salvatore Riegler4, Maria Luisa Brandi7,Luisella Cianferotti7, Alexandra Prados Torres6, Alessandra Marengoni8, Sergio Pecorelli9, Alessandro Monaco10

1-UCIBIO, Faculty of Pharmacy of University of Porto and porto4ageing, Portugal; 2- Psychology Unit of the S. Maugeri Foundation, IRCCS, Scientific Institute of Montescano, Italy; 3-Sanofi Pasteur MSD, France; 4-CIRFF, Center of Pharmacoeconomics University of Naples Federico II, Italy; 5- Daiichi Sankyo Europe, Germany; 6- Spanish National Health System, Aragon Health Sciences Institute (IACS) and Department of Preventive Medicine, Zaragoza University, Spain; 7- University of Florence, Italy; 8- Department of Clinical and Experimental Sciences, University of Brescia, Italy; 9- University of Brescia, Italy; 10- Italian Medicines Agency - AIFA, Italy.

Scientific Research and Advocacy on Adherence (SRAA) Group is created in the context of Action Group A1 of European Innovation Partnership on Active and Healthy Ageing (EIP-AHA)focused onincreasing the appropriateness of treatments and adherence to medical plans.

Adherence to healthy nutrition, active lifestyle, vaccines and medication, are the cornerstones of wellbeing in every age group. SRAA aims to drive structural changes on adherence issues far beyond the scope any one organization could achieve on its own and to innovate and experiment in real world settings, by bridging scientific activity into clinical practice through multidisciplinary approaches at European level.SRAA consortium brings together 37organisations from 11 European countries (Belgium,Croatia, France,Germany,Ireland, Italy, Netherlands,Poland, Portugal, Spain and Sweden). Consortium involves different stakeholders, namely regional governments and health and care providers, academia and research, industryand civil society. SRAA also includes two EIP-AHA reference sites (COLLAGE and porto4ageing). SRAAconsortiumshares a converging vision and common targets, where each organisation contributes actively to overall goal of responding more efficiently to societal/clinicalneeds, specifically in matters related to adherence to medical planin a European perspective. Consortium identified five priority areas to be addressed through holistic approaches: new consensus on adherence; impact and determinants of non-adherence; improve the appropriateness and adherence in multimorbidpolimedicatedpopulation; and tools and methodologies to improve adherence.

SRAA is also involved in advocacy activities finalized to sensitize opinion leaders and decision-makers to the negative impact ofnon-adherence in a public health/health economy perspective. SRAA is committed to promoting local, national and European convergence and improving the health innovation ecosystem. TransnationalSprint projects and collaborative works have been proved to be valid tools Europe-wide tofill the gap between public and private actions and, ultimately, facilitating knowledge exchanges and solutions’ scaling up.